Experience in the complex therapy of chronic leg ulcers

With patients suffering from chronic ulcers of the legs, it is necessary to meet a practical doctor relatively often both in a hospital setting and in a clinic. At the same time, despite the variety of methods of their treatment, the percentage of failures is still significant.

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Effect of Electrical Stimulation on Chronic Leg Ulcer Size and Appearance

Physical Therapy ◽

10.1093/ptj/83.1.17 ◽

2003 ◽

Vol 83 (1) ◽

pp. 17-28 ◽

Cited By ~ 83

Author(s):

Pamela E Houghton ◽

Cynthia B Kincaid ◽

Marge Lovell ◽

Karen E Campbell ◽

David H Keast ◽

...

Keyword(s):

Surface Area ◽

Electrical Current ◽

Leg Ulcers ◽

Wound Surface ◽

Initial Examination ◽

Sham Treatment ◽

Chronic Ulcers ◽

Arterial Insufficiency ◽

To Receive ◽

Chronic Leg Ulcers

Abstract Background and Purpose. Electrical current has been recommended for use on chronic pressure ulcers; however, the ability of this modality to improve healing of other types of chronic ulcers is less well established. The purpose of this study was to examine the effect of high-voltage pulsed current (HVPC) on healing of chronic leg ulcers. Subjects. Twenty-seven people with 42 chronic leg ulcers participated in the study. Methods. The subjects were separated into subgroups according to primary etiology of the wound (diabetes, arterial insufficiency, venous insufficiency) and then randomly assigned to receive either HVPC (100 microseconds, 150 V, 100 Hz) or a sham treatment for 45 minutes, 3 times weekly, for 4 weeks. Wound surface area and wound appearance assessed during an initial examination, following a 1- to 2-week period during which subjects received only conventional wound therapy, after 4 weeks of sham or HVPC treatment, and at 1 month following treatments. Results The results indicated that HVPC applied to chronic leg ulcers reduced the wound surface area over the 4-week treatment period to approximately one half the initial wound size (mean decrease=44.3%, SD=8.8%, range=2.8%-100%), which was over 2 times greater than that observed in wounds treated with sham units (mean decrease=16.0%, SD=8.9%, range=-30.3%-83.7%). Discussion and Conclusion. The results of the study indicate that HVPC administered 3 times a week should be considered to accelerate wound closure of chronic leg ulcers.

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Efficacy and Safety of Intralesional Platelet Rich Plasma (PRP) Therapy in the Management of Chronic Non-healing Leg Ulcers in our Population

10.53350/pjmhs2115102746 ◽

2021 ◽

Vol 15 (10) ◽

pp. 2746-2748

Author(s):

Muhammad Aslam Javed ◽

Sadaf Amin ◽

Wishal Raza ◽

Imran Yousuf

Keyword(s):

Chronic Wounds ◽

Platelet Rich Plasma ◽

Simple Procedure ◽

Cost Effective ◽

Leg Ulcers ◽

Weekly Basis ◽

Time Period ◽

Percentage Improvement ◽

Chronic Ulcers ◽

Chronic Leg Ulcers

Background: Autologous Platelets Rich Plasma (PRP) therapy not only hastens chronic wounds and ulcers healing but also diminishes the rate of amputations of lower leg caused by non-healing recalcitrant ulcers. In this study we have demonstrated the magical results of intralesional autologous PRP in the healing of resistant to heal chronic leg ulcers. Methods: In this metacentric study 26 patients having 30 chronic leg ulcers of more than 6 weeks duration and various etiologies, were treated with intralesional autologous PRP application on weekly basis for a duration of 8 weeks and the final results were calculated by percentage improvement in the volume and area of the ulcer/wound. Results: In our study 26 patient with 30 chronic recalcitrant leg ulcers/wounds were treated with intralesional autologous PRP therapy on weekly basis. Mean age of the included patients was 34.5 years. 19 were male patients and 7 were female. The mean time period of the healing of chronic ulcers was 5.3 weeks. The final mean percentage improvement outcome in the volume and area of the ulcers was calculated as 86% and 88% respectively. Conclusions: PRP therapy is safe, cost effective office based simple procedure in treating recalcitrant chronic leg ulcer/wounds. Keywords: Non-healing, intralesional, autologous platelet rich plasma, chronic ulcers

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Causes and the way of treatment of patients with chronic leg ulcers

Phlebologie ◽

10.1055/s-0037-1622275 ◽

2009 ◽

Vol 38 (05) ◽

pp. 211-218 ◽

Cited By ~ 2

Author(s):

C. Wax ◽

A. Körber ◽

J. Dissemond ◽

J. Klode

Keyword(s):

Treatment Period ◽

General Practitioners ◽

Peripheral Arterial Occlusive Disease ◽

Mean Value ◽

Arterial Occlusive Disease ◽

Leg Ulcer ◽

Leg Ulcers ◽

Patient Will ◽

Peripheral Arterial ◽

Chronic Leg Ulcers

SummaryChronic leg ulcer may have various causes, which are currently not centrally recorded in Germany. It is also unclear who treats patients with chronic leg ulcers in Germany and how the basic implementation of diagnosis and treatment of these patients looks like. Patients, methods: Therefore, we started a survey of 1000 general practitioners and practising specialists in dermatology, surgery and phlebology in five different regions of Germany. We carried out the genesis of a total of 6275 patients from 62 different practising therapists, 33 specialists in dermatology, surgery or phlebology and 29 general practitioners. Results: In 66.1% of all patients we found a venous leg ulcer, in 9.1% a leg ulcer from peripheral arterial occlusive disease, and in 8.5% a mixture of both. Thus there suffered a total of 83.8% of patients on chronic venous insufficiency or peripheral arterial occlusive disease as a major factor in the genesis of the chronic leg ulcer. However, even the rarely diagnosed entities such as exogenous factors, vasculitis, pyoderma gangrenosum or infectious diseases are occur in summation in 16.2% of all patients and should therefore be known and excluded. In addition, the treatment periods and referral routes of patients with chronic leg ulcer should be identified. The analysis showed that the vast majority (86.8%) of patients with chronic ulcers who were investigated by us is treated by specialists. The treatment duration of general practitioners is 6.3 weeks (mean value) before the patient will be referred to a specialist. This treatment period is significantly shorter compared to the treatment period of the specialists, who treat their patients 14.1 weeks (mean value) before the patient will be referred to another specialist or to a clinic. Conclusion: Our results show the current aspects of aetiology and the way of treatment of patients with chronic leg ulcers in Germany.

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