Relationship of background electroencephalogram with cognitive impairment in patients with alcohol dependence

A significant number of studies have focused on the neurophysiological basis of cognitive dysfunction among individuals with neurological and psychiatric disorders, including alcoholism. However, the neural correlates of cognitive deficits in alcohol dependence are still not clear enough. The purposeof the study: to identify the relationship of background electroencephalogram indicators with cognitive disorders in patients with alcohol dependence. Material and methods.107patients with alcohol dependence aged 30 to 60years after detoxification were examined. The background electroencephalogram was recorded with closed eyes for 2min. The values of the absolute spectral power of theta, alpha and beta rhythms were analyzed. The study of the level of Executive functioning was conducted using the Go/Nogo test. The level of spatially working memory was evaluated using the Corsi Block-Tapping test. Results.Data analysis revealed statistically significant correlations between the spectral power of the alpha rhythm in the occipital cortex and the number of errors per inhibitory signal (Nogo) in the Go/Nogo problem (r=0.287; p=0.025). There were also statistically significant correlations between the values of alpha-rhythm spectral power and working memory in the Corsi test in the parietal cortex (r=0.273; p=0.037), occipital cortex (r=0.316; p=0.015) and temporal cortex (r=0.359; p=0.005). There were no statistically significant correlations of beta and theta rhythms with the results of cognitive tests (p0.05). Conclusion.Thus, all of the above results indicate that the background EEG indicators, in particular the spectral power of alpha activity, can with a certain probability indicate violations of cognitive functioning (inhibitory control and working memory) in patients with alcohol dependence.

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Relationship of cognitive disorders with clinical features of alcohol dependence

Yakut Medical Journal ◽

10.25789/ymj.2020.70.19 ◽

2020 ◽

pp. 62-65

Author(s):

S.A. Galkin ◽

A.G. Peshkovskaya ◽

O.V. Roshchina ◽

N.I. Kisel ◽

S.A. Ivanova ◽

...

Keyword(s):

Alcohol Dependence ◽

Clinical Features ◽

Cognitive Disorders ◽

Relationship Of

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Spontaneous Eye Blink Rate during the Working Memory Delay Period Predicts Task Performance

10.1101/2021.03.15.435433 ◽

2021 ◽

Author(s):

Jefferson Ortega ◽

Chelsea Reichert Plaska ◽

Bernard A Gomes ◽

Timothy M Ellmore

Keyword(s):

Working Memory ◽

Task Performance ◽

Memory Task ◽

Delay Period ◽

Blink Rate ◽

Indirect Measure ◽

Eye Blink ◽

Non Invasive ◽

Relationship Of ◽

The Relationship

Spontaneous eye blink rate (sEBR) has been found to be a non-invasive indirect measure of striatal dopamine activity. Dopamine (DA) neurons project to the prefrontal cortex (PFC) through the mesocortical dopamine pathway and their activity is implicated in a range of cognitive functions, including attention and working memory (WM). The goal of the present study was to understand how fluctuations in sEBR during different phases of a working memory task relate to task performance. Across two experiments, with recordings of sEBR inside and outside of a magnetic resonance imaging bore, we observed sEBR to be positively correlated with WM performance during the WM delay period. Additionally we investigated the non-linear relationship between sEBR and WM performance, and modeled a proposed Inverted-U-shape relationship between DA and WM performance. We also investigated blink duration, which is proposed to be related to sustained attention, and found blink duration to be significantly shorter during the encoding and probe periods of the task. Taken together, these results provide support towards sEBR as an important correlate of working memory task performance. The relationship of sEBR to DA activity and the influence of DA on the PFC during WM maintenance is discussed.

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Complex syntax and working memory in children with specific learning difficulties

First Language ◽

10.1177/0142723719889240 ◽

2019 ◽

Vol 40 (4) ◽

pp. 411-436 ◽

Cited By ~ 3

Author(s):

Emily Stanford ◽

Hélène Delage

Keyword(s):

Working Memory ◽

Processing System ◽

Learning Disorder ◽

Complex Syntax ◽

Specific Learning Disorder ◽

Wh Questions ◽

Digit Recall ◽

Relationship Of ◽

The Relationship ◽

Specific Learning

Working memory (WM) limitations are frequently reported for children with specific learning disorder (SLD). However, WM capacity influences more than literacy and numeracy, as research highlights the contribution of WM to language development, in particular syntax. In this article, the authors study the effect of syntactic intervention, i.e. syntactic elements intervening between filler and gap, on comprehension in children with SLD and evaluate the relationship of this effect to WM capacity. Specifically, they assess how these children comprehend wh-questions and relative clauses. Additionally, they examine how comprehension relates to WM, measured by backward digit recall. The authors report that a subgroup of children with SLD struggle to comprehend structures containing intervention, and that WM capacity influences performance in SLD. Their conclusion is that computing a syntactic relation in which a moved object and an intervening subject share a featural specification taxes the processing system of children with SLD who have WM limitations. Thus, syntactic difficulties, although not typically associated with SLD, may form part of the SLD profile, especially when WM capacity is reduced.

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The Relationship of Anxiety and Stress With Working Memory Performance in a Large Non-depressed Sample

Frontiers in Psychology ◽

10.3389/fpsyg.2019.00004 ◽

2019 ◽

Vol 10 ◽

Cited By ~ 5

Author(s):

Karolina M. Lukasik ◽

Otto Waris ◽

Anna Soveri ◽

Minna Lehtonen ◽

Matti Laine

Keyword(s):

Working Memory ◽

Memory Performance ◽

Relationship Of ◽

The Relationship

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The Relationship Of Age, Igf-1 And Bdnf To Working Memory In Healthy Older Adults

Medicine & Science in Sports & Exercise ◽

10.1249/01.mss.0000385543.36993.f1 ◽

2010 ◽

Vol 42 ◽

pp. 72

Author(s):

David Bellar ◽

John Gunstad ◽

Ellen L. Glickman

Keyword(s):

Older Adults ◽

Working Memory ◽

Healthy Older Adults ◽

Relationship Of ◽

The Relationship

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The Relationship of Executive Functions and Speech Production in Senior Preschool Children: Working Memory and Storytelling

Clinical Psychology and Special Education ◽

10.17759/cpse.2019080304 ◽

2019 ◽

Vol 8 (3) ◽

pp. 56-84 ◽

Cited By ~ 1

Author(s):

A.N. Veraksa ◽

E. Ochepkova ◽

D.A. Bukhalenkova ◽

N. Kartushina

Keyword(s):

Working Memory ◽

Preschool Children ◽

Verbal Working Memory ◽

Speech Development ◽

Memory Development ◽

Semantic Completeness ◽

And Cluster Analysis ◽

Relationship Of ◽

The Relationship ◽

Global Indicators

The article presents the data of the study of working memory and features of oral monologue speech in preschool children. 269 children (133 boys and 136 girls) aged 5-6 years (M=5.6 years; Sd=0.48) attending the senior group of kindergarten in Moscow were examined. Features of oral monologue speech development were studied using methods developed in the Russian neuropsychology: tasks for retelling the text and compiling the story of a series of pictures. General neuropsychological parameters, separate lexical and grammatical (morphology and syntax) indicators, macrostructure of the narrative were analyzed in the evaluation of children's responses. As a result of the correlation and cluster analysis, similar links were obtained: the level of working memory development in preschoolers is correlated with such indicators of the child's speech development as semantic completeness of the text, its adequacy, programming of speech message, the number of words and sentences in the text, the development of macrostructure and the type of narrative. Based on the results, it is concluded that the most general and global indicators of the macrostructure of the text are significantly associated with the development of working memory. At the same time, the development of verbal working memory is more associated with the development of speech in preschool children compared to visual working memory. The authors come to the conclusion that with a well-developed auditory working memory, the child's speech will be more correct lexically and grammatically.

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The relationship of age and DRD2 polymorphisms to frontostriatal brain activity and working memory performance

Neurobiology of Aging ◽

10.1016/j.neurobiolaging.2019.08.022 ◽

2019 ◽

Vol 84 ◽

pp. 189-199

Author(s):

Xin Li ◽

Lars Bäckman ◽

Jonas Persson

Keyword(s):

Working Memory ◽

Brain Activity ◽

Memory Performance ◽

Relationship Of ◽

The Relationship

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Subclinical hypothyroidism: treat or watch?

Bulletin of the Medical Institute "REAVIZ" (REHABILITATION, DOCTOR AND HEALTH) ◽

10.20340/vmi-rvz.2020.6.12 ◽

2021 ◽

pp. 98-108

Author(s):

I. A. Tsanava ◽

S. V. Bulgakova ◽

A. V. Melikova

Keyword(s):

Thyroid Hormones ◽

Subclinical Hypothyroidism ◽

Metabolic Disorders ◽

Reference Range ◽

Cognitive Disorders ◽

The Body ◽

Relationship Of ◽

The Relationship ◽

Serum Tsh ◽

Tsh Levels

Manifest hypothyroidism occurs in more than 5 % of the population, while prevalence of subclinical hypothyroidism is much higher and reaches 15 %. In the practice of an endocrinologist, in most cases, the diagnosis and treatment of manifest hypothyroidism does not raise questions, while subclinical changes in thyroid hormones quite often generate a lot of discussions. The generally accepted reference range for TSH up to 4.50 μIU / ml is in conflict with data showing that more than 95 % of healthy people with euthyroidism have serum TSH levels up to 2.5 μIU / ml. At the same time, a lot of data has been accumulated on the effect of even slightly altered levels of thyroid hormones and TSH on various tissues, organs and systems of the body, especially on the cardiovascular, nervous and reproductive systems. This review analyzes the results of studies aimed at studying the relationship of subclinical hypothyroidism with cardiovascular and metabolic disorders, cognitive disorders, pathology of pregnant women.

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