scholarly journals Prof. Treupel. Further observations on injections of Ehrlich Hata, especially in syphilis of the central nervous system, in tabes dorsalis and paralysisѣ.Weitere Erfarungen mit Ehrlich-Hata Injectionen, insbesondere bei Lues des zentralen Nervensystem bei Tabes und Paralyse.—Münch. med. Woch. 1910, №46

2021 ◽  
Vol XVIII (2) ◽  
pp. 505-507
Author(s):  
Vitaliy N. Likhnitsky
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Tabes Dorsalis ◽  
The Central Nervous System

The author produced injections of Ehrlich Hata for syphilis of the central nervous system, for tabes dorsalis and paralysis progressiva. The most favorable results were obtained by him in syphilis of the central nervous system.

Some Points in the Histology of Lymphogenous and Hæmatogenous Toxic Lesions of the Spinal Cord

1908 ◽  
Vol 54 (226) ◽  
pp. 560-561
Author(s):  
David Orr ◽  
R. G. Rows
Keyword(s):  
Spinal Cord ◽  
Central Nervous System ◽  
Nervous System ◽  
Sciatic Nerve ◽  
Morphological Type ◽  
Broth Culture ◽  
Anatomical Distribution ◽  
Tabes Dorsalis ◽  
The Central Nervous System ◽  
The Brain

At a quarterly meeting of this Association held last year at Nottingham, we showed the results of our experiments with toxins upon the spinal cord and brain of rabbits. Our main conclusion was, that the central nervous system could be infected by toxins passing up along the lymph channels of the perineural sheath. The method we employed in our experiments consisted in placing a celloidin capsule filled with a broth culture of an organism under the sciatic nerve or under the skin of the cheek; and we invariably found a resulting degeneration in the spinal cord or brain, according to the situation of the capsule. These lesions we found to be identical in morphological type and anatomical distribution with those found in the cord of early tabes dorsalis and in the brain and cord of general paralysis of the insane. The conclusion suggested by our work was that these two diseases, if toxic, were most probably infections of lymphogenous origin.

Maceste and its importance in the treatment of diseases of the nervous system

1927 ◽  
Vol 23 (4) ◽  
pp. 464-464
Author(s):  
V. I. Znamensky
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Cardiovascular System ◽  
Peripheral Nervous System ◽  
Tabes Dorsalis ◽  
The Central Nervous System ◽  
The Brain

According to V. I. Znamensky indicated for treatment in Matsesta: 1) diseases of the peripheral nervous system, -neuralgia, neuritis; 2) diseases of the central nervous system connected with disorders of the cardiovascular system, - hemiplegia and hemiparesis due to thrombosis and embolism; (treatment of acute forms of the mentioned diseases, it goes without saying, is contraindicated); 3) Luetic diseases,-vascular syphilis of the brain, lues cerebrospinalis, meningo-myelitis, tabes dorsalis incipiens and Luetic radiculitis (here; baths, giving increase of metabolism and excretions, make possible mercury treatment with impunity); 4) remnants of lethargic encephalitis.

The development and current state of the science on pathological and anatomical changes in dorsal tabes

1901 ◽  
Vol IX (2) ◽  
pp. 1-81
Author(s):  
N. N. Stern
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Clinical Course ◽  
Pathological Changes ◽  
Anatomical Changes ◽  
Current State ◽  
Tabes Dorsalis ◽  
The Central Nervous System ◽  
State Of The Science ◽  
Pathologische Anatomie

In 1882, Strumpell published his famous work: "Die pathologische Anatomie der tabes dorsalis". In the introduction to this work, he says: already the clinical course of a typical dorsal tabes, with a more thorough examination, suggests that pathological changes in this disease, in contrast to many other diseases of the central nervous system, always occupy strictly defined areas of the central nervous system.

A Demonstration of the Lesions, experimentally produced, in the Spinal Cord and Cranial Nerves by the Action of Toxins

1907 ◽  
Vol 53 (221) ◽  
pp. 367-369
Author(s):  
Orr ◽  
Rows
Keyword(s):  
Spinal Cord ◽  
Central Nervous System ◽  
Nervous System ◽  
Cranial Nerves ◽  
General Paralysis ◽  
Tabes Dorsalis ◽  
The Central Nervous System

In a previous paper we described the lesions in the posterior columns of the spinal cord in cases of general paralysis, and pointed out their similarity with those in early tabes dorsalis. We showed that the degeneration always commenced at the point where the posterior roots enter the cord. It is here that the sensory fibres become part of the central nervous system and lose their neurilemma sheath; and in all cases we found that precisely at this point degeneration began.

scholarly journals Canadian Public Health Laboratory Network laboratory Guidelines for the Diagnosis of Neurosyphilis in Canada

2015 ◽  
Vol 26 (supplement a) ◽  
pp. 18A-22A ◽  
Author(s):  
Tom Wong ◽  
Kevin Fonseca ◽  
Max A Chernesky ◽  
Richard Garceau ◽  
Paul N Levett ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Vision Loss ◽  
Direct Detection ◽  
Treponema Pallidum ◽  
Sample Collection ◽  
Clinical Syndromes ◽  
Tabes Dorsalis ◽  
Antibody Assays ◽  
The Central Nervous System

Neurosyphilis refers to infection of the central nervous system byTreponema pallidum, which may occur at any stage. Neurosyphilis has been categorized in many ways including early and late, asymptomatic versus symptomatic and infectious versus non-infectious. Late neurosyphilis primarily affects the central nervous system parenchyma, and occurs beyond early latent syphilis, years to decades after the initial infection. Associated clinical syndromes include general paresis, tabes dorsalis, vision loss, hearing loss and psychiatric manifestations. Unique algorithms are recommended for HIV-infected and HIV-uninfected patients, as immunocompromised patients may present with serologic and cerebrospinal fluid findings that are different from immunocompetent hosts. Antibody assays include a VDRL assay and the FTA-Abs, while polymerase chain reaction forT. pallidumcan be used as direct detection assays for some specimens. This chapter reviews guidelines for specimen types and sample collection, and identifies two possible algorithms for use with immunocompromised and immunocompetent hosts using currently available tests in Canada, along with a review of treatment response and laboratory testing follow-up.

Effects of Hyperoxia on Lung Utrastructure

1970 ◽  
Vol 28 ◽  
pp. 26-27
Author(s):  
Gladys Harrison
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Light Microscopy ◽  
Oxygen Effects ◽  
Age Dependent ◽  
The Central Nervous System ◽  
The Subject ◽  
Space Age ◽  
Alveolar Septa ◽  
Extensive Damage

With the advent of the space age and the need to determine the requirements for a space cabin atmosphere, oxygen effects came into increased importance, even though these effects have been the subject of continuous research for many years. In fact, Priestly initiated oxygen research when in 1775 he published his results of isolating oxygen and described the effects of breathing it on himself and two mice, the only creatures to have had the “privilege” of breathing this “pure air”.Early studies had demonstrated the central nervous system effects at pressures above one atmosphere. Light microscopy revealed extensive damage to the lungs at one atmosphere. These changes which included perivascular and peribronchial edema, focal hemorrhage, rupture of the alveolar septa, and widespread edema, resulted in death of the animal in less than one week. The severity of the symptoms differed between species and was age dependent, with young animals being more resistant.

Emigration of neutrophils in the central nervous system

1983 ◽  
Vol 41 ◽  
pp. 788-789
Author(s):  
John L.Beggs ◽  
John D. Waggener ◽  
Wanda Miller ◽  
Jane Watkins
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Osmium Tetroxide ◽  
White Blood Cells ◽  
Arterial Perfusion ◽  
E Coli ◽  
Intracisternal Injection ◽  
The Central Nervous System ◽  
Brain And Spinal Cord ◽  
Interendothelial Junctions

Studies using mesenteric and ear chamber preparations have shown that interendothelial junctions provide the route for neutrophil emigration during inflammation. The term emigration refers to the passage of white blood cells across the endothelium from the vascular lumen. Although the precise pathway of transendo- thelial emigration in the central nervous system (CNS) has not been resolved, the presence of different physiological and morphological (tight junctions) properties of CNS endothelium may dictate alternate emigration pathways.To study neutrophil emigration in the CNS, we induced meningitis in guinea pigs by intracisternal injection of E. coli bacteria.In this model, leptomeningeal inflammation is well developed by 3 hr. After 3 1/2 hr, animals were sacrificed by arterial perfusion with 3% phosphate buffered glutaraldehyde. Tissues from brain and spinal cord were post-fixed in 1% osmium tetroxide, dehydrated in alcohols and propylene oxide, and embedded in Epon. Thin serial sections were cut with diamond knives and examined in a Philips 300 electron microscope.

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