scholarly journals Combined (citrate and herbal) drug uriklar in extracorporeal shock wave lithotripsy and metaphylaxis of urolithiasis

2018 ◽  
Vol 8 (1) ◽  
pp. 19-25
Author(s):  
Aleksandr Yu Shestaev ◽  
Vladimir V Protoshchak ◽  
Mikhail V Paronnikov ◽  
Artyem O Kiselev

The aim of the study was to study the clinical efficiency and safety of the drug uriklar in extracorporeal shock wave lithotripsy (ESWL) and early metaphylaxis of urolithiasis. Materials and methods. 45 patients were included in the prospective study. The patients were divided into two groups. The main group consisted of 25 patients, they received uriklar 1 capsule three times a day for one month before and three after ESWL. The control group included 20 patients who underwent ESWL only. Uriklar is combined drug with citrate and herbal components. Results. The total efficiency of ESWL was 92% in I group versus 75% in control group. Among the patients of the main group, the frequency of renal colic after ESWL was 24% (6 patients), while in the control group colic occurred in 9 patients (45%). The severity of pain syndrome was of 5.12 ± 2.1 in I group and of 7.48 ± 2.2 and in II group (p < 0.05). Uriklar in the first group of patients increased the pH of urine and the excretion of citrate significantly and decreased excretion of uric acid. After 3 months, the vast majority of patients (n = 24, 96%) of the main group underwent curing of the urinary tract, and daily diuresis remained at 2.3 ± 0.3 l/day. Conclusions. The uriklar taking increases the fragmentation of urinary stones and the elimination of the resulting fragments from the urinary tract, promotes the normalization of metabolic disorders, and effectively eliminates infectious-inflammatory complications of urolithiasis. It is also well-tolerated and has no side effects. (For citation: Shestaev AYu, Protoshchak VV, Paronnikov MV, Kiselev AO. Combined (citrate and herbal) drug uriklar in extracorporeal shock wave lithotripsy and metaphylaxis of urolithiasis. Urologicheskie vedomosti. 2018;8(1):19-25. doi: 10.17816/uroved8119-25).

2018 ◽  
Vol 6 ◽  
pp. 3-9
Author(s):  
Volodymir Vitkovskyy

The study objective was to analyse the effect of the herbal drug Canephron N, namely, its ability to potentiate the efficacy of extracorporeal shock wave lithotripsy (ESWL) in the treatment of patients with urolithiasis (UL) and prevent recurrence of stone formation. Aim. To сheck the hypothesis that treatment with Canephron N can potentiate lithotripsy and reduce the risk of re-stone formation. Methodology. Patients at the age of 18 to 65 years had calcium oxalate urolithiasis with the size of the stone from 0.8 to 1.3 cm in the kidneys and from 0.5 to 0.9 cm. in ureters who underwent ESWL procedure. They were randomized into 2 equal groups of 30 people. The treatment group received general recommendations on the management of the patient with UL following ESWL and the herbal drug Canephron N for 6 months. The control group received only general recommendations. Moreover, according to condition, both groups received painkillers and spasmolytics if pain occurred during elimination of fragments. The following parameters were evaluated: the period of elimination of fragments after stone disintegration by ESWL method; the percentage of complete elimination of fragments; the presence of pain syndrome and leukocyturia in the postoperative period; the rate of recurrence of stone formation during one year after the procedure. Results. More complete and rapid elimination of fragments was observed in the treatment group. Thus, up to day 14 elimination of stone fragments was observed in 96.6 % of patients in the treatment group versus 76.6 % in the control group. Fewer cases of pain syndrome during elimination of stone fragments (23 % in the treatment group and 43 % in the control group) and rare cases of leukocyturia within 14 days (10 % versus 23 %, respectively) were observed in the treatment group. Recurrent stone formation within the year was not observed in patients of the treatment group, in the control group – in 23 % of patients. However, because of the small size of the groups, one may talk about a tendency but not about statistically significant patterns. Conclusion. Canephron N is an effective and safe drug in the treatment of patients with urolithiasis who underwent extracorporeal shock wave lithotripsy. Its use contributes to more rapid and safe elimination of fragments of destructed calculi and reduces risk of recurrent stone formation.


2020 ◽  
Vol 3 (2) ◽  
pp. e16-e19
Author(s):  
Musaab Yassin ◽  
Abigail Cressey ◽  
Louise Goldsmith ◽  
Ben Turney ◽  
John Reynard

Ureteroscopy and extracorporeal shock wave lithotripsy (ESWL) are two widely used methods for the treatment of ureteric and pelviureteric junction (PUJ) stones. ESWL remains the only non-invasive therapy modality for the treatment of urinary stones. Extracorporeal shock wave lithotripsy (ESWL) is a non-invasive, safe and effective treatment for urinary tract lithiasis Ureteroscopy and extracorporeal shock wave lithotripsy (ESWL) are two widely used methods for the treatment of ureteric and pelviureteric junction (PUJ) stones. ESWL remains the only non-invasive therapy modality for the treatment of urinary stones. Extracorporeal shock wave lithotripsy (ESWL) is a non-invasive,safe and effective treatment for urinary tract lithiasis ObjectivesTo evaluate the effectiveness of emergency “hot” shock wave lithotripsy in treating symptomatic ureteric/ PUJ stones. Materials and MethodsA retrospective study looking at the emergency referrals for shock wave lithotripsy to the Churchill Hos-pital between June 2013 to Dec 2017. The Lithotripsy Database and patients’ electronic records were used to complete this project. Emergency referrals triaged by the on-call urology team and go through a renal colic clinic. ResultsIn total, 201 patients underwent emergency shock wave lithotripsy for ureteric/PUJ stones.The mean stone size was 7.7mm (SD 2.9). 12.4% (25) were PUJ, 45.3% (91) proximal and 42.3% (85) distal ureteric stones. 1% (2) were bilateral ureteric stones. 9% (18) had previous lithotripsy treatment before being referred.The number of shocks used was 4000 in 52.7%, >=3000 in 40.3%, >=2000 in 4.5% and >=1000 in 2.5%. The median shock frequency was 2 Hz. The median number of treatments for the targeted stone was 2. Stone fragmentation was visible in 27.4% (55), possible in 30.8% (62) and not visible in 41.8% (84).In terms of follow up, 48.3% (97) were discharged stone-free, while 17.4% (35) were discharged with residual fragments. 21.8% (44) had further clinic follow up while 12.4% (25) had no follow-up information available, possibly because they were referred from different hospitals. 19.9% (40) needed ureteroscopy, while 7% (14) needed further lithotripsy sessions. ConclusionsEmergency extracorporeal lithotripsy can be offered as an effective and safe treatment for patients with symptomatic stones.


2012 ◽  
Vol 94 (1) ◽  
pp. 8-11 ◽  
Author(s):  
A Young ◽  
M Ismail ◽  
AG Papatsoris ◽  
JM Barua ◽  
JG Calleary ◽  
...  

INTRODUCTION Entonox® (50% nitrous oxide and 50% oxygen; BOC Healthcare, Manchester, UK) is an analgesic and anxiolytic agent that is used to successfully reduce pain and anxiety during dental, paediatric and emergency department procedures. In this article we review the application and efficacy of Entonox® in painful local anaesthesia urological procedures by performing a systematic review of the literature. METHODS A MEDLINE® search was performed using the terms ‘nitrous oxide’, ‘Entonox’, ‘prostate biopsy’, ‘flexible cystoscopy’ and ‘extracorporeal shock wave lithotripsy’. English language publications of randomised studies were identified and reviewed. RESULTS The search yielded five randomised studies that investigated the clinical efficacy of Entonox® as an analgesic for day case urological procedures. Three randomised controlled trials (RCTs) investigated Entonox® in transrectal ultrasonography guided prostate biopsy. All three reported significant reductions in pain score in the Entonox® versus control groups. One RCT reported significant reduction in pain during male flexible cystoscopy in the Entonox® group compared with the control group. One RCT, which examined the use of Entonox® during extracorporeal shock wave lithotripsy, found its use significantly decreased the pain score compared with the control group and this was comparable to intravenous pethidine. CONCLUSIONS Evidence from varied adult and paediatric procedures has shown Entonox® to be an effective, safe and patient acceptable form of analgesia. All published studies of its use in urological day case procedures have found it to significantly reduce procedural pain. There is huge potential to use this cheap, safe, effective analgesic in our current practice.


2018 ◽  
Vol 1 (2) ◽  
pp. 102-104
Author(s):  
Dhruba Bahadur Adhikari ◽  
David Shrestha ◽  
Anup Shrestha

Introduction: The aim of the study was to observe the success rate of extracorporeal shock wave lithotripsy (ESWL) in the management of upper urinary tract stones. Materials and Methods: This retroprospective study was conducted in Pokhara Kidney stone Centre, Pokhara, Kaski, Nepal from January 2017 to January 2018. Seventy nine patients were selected in this study with upper urinary tract stone, size less than 20 mm. Results: Seventy four (93.67%) patients were successfully treated in initial use of shock wave and 5 (6.32%) patients required repetition. Conclusion: Overall satisfactory success rate was observed using ESWL for the upper urinary tract stone. Careful selection of patient, stone size and Hounsfield unit (HU) is advisable.


2019 ◽  
Vol 18 (7) ◽  
pp. e2890
Author(s):  
A. Artiles Medina ◽  
I. Laso García ◽  
G. Duque Ruiz ◽  
J. Brasero Burgos ◽  
M. Ruiz Hernández ◽  
...  

QJM ◽  
2020 ◽  
Vol 113 (Supplement_1) ◽  
Author(s):  
A S Hegazy ◽  
D M Abdelfattah ◽  
H N Hassan

Abstract Background Radiopaque stones in the upper urinary tract can often be visualized by both ultrasonography (US) and fluoroscopy (FS) during ESWL treatment. This prospective study was performed to compare the results of ESWL when both US and FS are possible and to evaluate efficacy and safety of ultrasound guided ESWL (SONO ESWL) in patients with radiopaque renal stone. The study was limited to renal calculi, since calculi in lower urinary tract may be difficult to visualize with ultrasonography. Objective To investigate whether the localization modality (u/s or fluoroscopy) affects clinical outcomes of ESWL or not. Patients and Methods Our study was conducted on 100 Patients with renal stones planned to have ESWL sessions attending urology outpatient clinic in Ain shams university hospitals and National Institute of Urology and Nephrology from February 2018 to January 2019 and divided into two equal groups; group A (ultrasound guided ESWL) and group B (fluoroscope guided ESWL). Results Our study revealed that the localization modality on ESWL (ultrasound or fluoroscopy) didn’t affect the clinical outcomes of ESWL. Conclusion Even in patients with radiopaque renal stones, ultrasound can be used to guide extracorporeal shock wave lithotripsy as effectively as fluoroscopy, without any risk of radiation.


2013 ◽  
Vol 9 (3) ◽  
pp. 323-327 ◽  
Author(s):  
Enmar I. Habib ◽  
Hany A. Morsi ◽  
Mohammed S. ElSheemy ◽  
Waseem Aboulela ◽  
Mohamed A. Eissa

1987 ◽  
Vol 3 (3) ◽  
pp. 397-404 ◽  
Author(s):  
Elaine J. Power

AbstractExtracorporeal shock wave lithotripsy (ESWL) for upper urinary stones has been in use in the United States since 1984. It was accepted immediately by hospitals and physicians, and its diffusion has been and continues to be rapid. Government payment and planning policies do not seem to have slowed this diffusion, although they have had some effect on the ownership of lithotripters and the manner in which ESWL is provided. An unintended but foreseeable result of ESWL's popularity with hospitals, physicians, and patients is that ESWL is not only rapidly replacing traditional surgery but is being used on many patients who would not have had surgery. It is likely that many more upper urinary stones are being treated aggressively now than before ESWL was introduced.


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