Reconstruction of a Reference Subsoil Model for the Seismic Microzonation of Gori (Georgia): A Procedure Based on Principal Component Analysis (PCA)

Author(s):  
Silvia Giallini ◽  
Enrico Paolucci ◽  
Pietro Sirianni ◽  
Dario Albarello ◽  
Iolanda Gaudiosi ◽  
...  

ABSTRACT This article focuses on the full exploitation of geological and economically viable geophysical surveys for the seismic characterization of the shallow subsoil in the frame of microzonation studies in urban areas where economic resources for detailed seismic response analyses are scarce. In these conditions, the outcomes of inexpensive geophysical surveys (e.g., based on ambient vibration monitoring or surface-wave prospecting) must be fully exploited. To reduce the uncertainties related to these kinds of procedures, their joint interpretation in the light of geological evidence is mandatory. To this purpose, we propose the application of principal component analysis to combine the results of distributed single-station ambient vibration measurements (horizontal-to-vertical spectral ratio [HVSR] technique) to provide a preliminary zonation of the study area. The zones identified in this way are then characterized by considering the available geognostic boreholes, VS profiles deduced by the joint inversion of HVSR curves, and available Rayleigh-wave dispersion curves deduced from active seismic prospecting (multichannel analysis of surface-waves technique). The final outcome allows the definition of a preliminary seismic model of the study area, which is also constrained by the available geological data deduced from on-purpose surveys. The proposed approach has been applied to the city of Gori (Georgia). The proposed approach allowed a reliable assessment of buried geometries, geological domains, and the distribution of lithofacies, which can control the local seismic response. In detail, the major role of paleovalley infills and interfluve domains has been enlightened by adding in evidence concerning the peculiar stratigraphic relationships and buried morphologies, which may determine 1D and 2D resonance effects.

Author(s):  
Chen Zhongsheng ◽  
Yang Yongmin ◽  
Guo Bin ◽  
Hu Zheng

Damage prognosis of high-speed blades is very important for industrial turbomachinery. Nowadays, vibration monitoring using blade tip-timing methods is becoming promising. However, its main drawback is blade tip-timing signals are subsampled. Very few works have been done on damage prognosis using subsampled blade tip-timing signals. This paper investigates a novel method of blade damage prognosis based on kernel principal component analysis and grey model. Firstly, a nonaliasing reconstruction algorithm of subsampled blade tip-timing signals is proposed based on the Shannon theorem and wavelet packet transform. Secondly, kernel principal component analysis is done on the damage feature space and a damage index is defined by Mahalanobis distance. Then a grey model (1) model is proposed for damage prognosis. In the end, an experimental setup is built and a long time testing is done for collecting samples. The experimental results validate the superiority of the proposed method.


VASA ◽  
2012 ◽  
Vol 41 (5) ◽  
pp. 333-342 ◽  
Author(s):  
Kirchberger ◽  
Finger ◽  
Müller-Bühl

Background: The Intermittent Claudication Questionnaire (ICQ) is a short questionnaire for the assessment of health-related quality of life (HRQOL) in patients with intermittent claudication (IC). The objective of this study was to translate the ICQ into German and to investigate the psychometric properties of the German ICQ version in patients with IC. Patients and methods: The original English version was translated using a forward-backward method. The resulting German version was reviewed by the author of the original version and an experienced clinician. Finally, it was tested for clarity with 5 German patients with IC. A sample of 81 patients were administered the German ICQ. The sample consisted of 58.0 % male patients with a median age of 71 years and a median IC duration of 36 months. Test of feasibility included completeness of questionnaires, completion time, and ratings of clarity, length and relevance. Reliability was assessed through a retest in 13 patients at 14 days, and analysis of Cronbach’s alpha for internal consistency. Construct validity was investigated using principal component analysis. Concurrent validity was assessed by correlating the ICQ scores with the Short Form 36 Health Survey (SF-36) as well as clinical measures. Results: The ICQ was completely filled in by 73 subjects (90.1 %) with an average completion time of 6.3 minutes. Cronbach’s alpha coefficient reached 0.75. Intra-class correlation for test-retest reliability was r = 0.88. Principal component analysis resulted in a 3 factor solution. The first factor explained 51.5 of the total variation and all items had loadings of at least 0.65 on it. The ICQ was significantly associated with the SF-36 and treadmill-walking distances whereas no association was found for resting ABPI. Conclusions: The German version of the ICQ demonstrated good feasibility, satisfactory reliability and good validity. Responsiveness should be investigated in further validation studies.


2020 ◽  
Vol 4 (11) ◽  
pp. 676-681
Author(s):  
V.V. Sapozhnikova ◽  
◽  
A.L. Bondarenko ◽  

Aim: to determine the association between clinical laboratory parameters, the production of cytokines (IL-17A, -23, -33, -35), and specific IgM and IgG in the serum of patients with Lyme borreliosis without erythema migrans. Patients and Methods: complete blood count, the concentrations of IL-17A, -23, -33, -35, and the levels of specific IgM and IgG were measured during acute infection and convalescence (n=30). The control group included age- and sex-matched healthy individuals (n=30). Statistical analysis was performed using the StatSoft Statistica v 10.0 software (parametric and non-parametric methods and multifactorial analysis, i.e., principal component analysis). Results: most (80%) patients with Lyme borreliosis without erythema migrans are the people of working age. In most patients, the combination of the specific antibodies against Borrelia afzelii and Borrelia garinii (76.7%) and severe intoxication and inflammatory process (100%) were detected. Moderate and severe disease associated with meningism was diagnosed in 90% and 10%, respectively. The mean duration of hectic period was 8.3±1.27 days. Abnormal ECG was reported in 40% of patients, i.e., conduction abnormalities in 20%, sinus bradycardia in 16.7%,and sinus tachycardia in 3.3%. The clinical laboratory signs of hepatitis without jaundice were identified in 26.7%. During treatment, the significant reduction in band and segmented neutrophil counts as well as the significant increase in platelet count were revealed compared to these parameters at admission. Abnormal cytokine levels (i.e., the increase in IL-17A, -23, -33 and the deficiency of IL-35) were detected. Conclusions: multifactorial analysis has demonstrated that the severity of immunological abnormalities in patients with Lyme borreliosis without erythema migrans is associated with fever, cardiac and liver disorders, the high levels of IL-23 and IL-33, and the lack of IL-35 and specific IgM and IgG. KEYWORDS: tick-borne borreliosis, Lyme disease without erythema migrans, clinical laboratory signs, cytokines, specific antibodies, multifactorial analysis, principal component analysis. FOR CITATION: Sapozhnikova V.V., Bondarenko A.L. Multifactorial analysis of clinical laboratory signs, the levels of IL-17A, IL-23, IL-33, IL-35, and specific antibodies in the serum of patients with Lyme borreliosis without erythema migrans. Russian Medical Inquiry. 2020;4(11):676–681. DOI: 10.32364/2587-6821-2020-4-11-676-681.


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