Reproductive History as a Surrogate for Lifetime Exposure to Unopposed Estrogen and Potential Mediation of its Association with Cardiovascular Disease by Inflammation

2021 ◽  
Author(s):  
Pam Phojanakong
2011 ◽  
Vol 40 (6) ◽  
pp. 1510-1518 ◽  
Author(s):  
L. G. Gallagher ◽  
L. B. Davis ◽  
R. M. Ray ◽  
B. M. Psaty ◽  
D. L. Gao ◽  
...  

ESC CardioMed ◽  
2018 ◽  
pp. 3099-3101
Author(s):  
Thomas Münzel ◽  
Sanjay Rajagopalan ◽  
Mette Sørenson ◽  
Dave Newby ◽  
Robert D. Brook

Cardiovascular disease represents the result of underlying genetic predisposition and lifetime exposure to multiple environmental factors. The past century has seen a revolution in our understanding of the importance of modifiable risk factors such as diet, exercise, and smoking. Exposure to environmental pollutants, be it in the air, water, or physical environment, is increasingly recognized as a silent, yet important determinant of cardiovascular disease. The cardiovascular system is highly vulnerable to a variety of environmental insults, including tobacco smoke, solvents, pesticides, and other inhaled or ingested pollutants, as well as extremes in noise and temperature. While our understanding of multiple environmental factors continues to evolve, it is estimated that environmental air pollution and noise pollution alone contribute a substantial burden attributable to environmental factors as we currently understand them.


Maturitas ◽  
1999 ◽  
Vol 33 (1) ◽  
pp. 7-36 ◽  
Author(s):  
Miriam J.J. de Kleijn ◽  
Yvonne T. van der Schouw ◽  
Yolanda van der Graaf

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