scholarly journals CORRELATION BETWEEN PROLINE-PROLINE/HYDROXY-PROLINE IN COLLAGEN PROTEINS AND THE MOISTURE CONTENT OF THE STRATUM CORNEUM AFTER ORAL INGESTION

2013 ◽  
Vol 7 (1) ◽  
pp. 71-75
Author(s):  
Yuri Mukai ◽  
Keitaro Machino ◽  
Kenji Etchuya ◽  
Hirotaka Tanaka ◽  
Takanori Sasaki
1997 ◽  
Vol 67 (8) ◽  
pp. 585-592 ◽  
Author(s):  
Bruce A. Cameron ◽  
Donna M. Brown ◽  
Merry Jo Dallas ◽  
Brenda Brandt

The effects of fabric made from natural and synthetic fibers and film on transepidermal water loss (tewl) from the stratum corneum (sc) were investigated using an occluded system. Sixteen fabrics differing in fiber type and construction were placed on the volar forearm of 35 female subjects in a dry state (standard moisture regain) and a wetted state. Each fabric was in place for 40 minutes before tewl was measured. There was no statistically significant difference in tewl measurements on a control skin site from the beginning to the end of the 75-minute test session in a controlled conditioned environment. Placement of dry fabrics on the skin did not significantly affect the hydration level of the sc, though all dry fabrics did increase the hydration level slightly. Wetted wool and cotton fabrics significantly hydrated the sc when levels were compared to either normal skin or skin covered by dry fabrics. Of the seven synthetic fiber fabrics tested in a wetted state, three (acrylic, ptfe, and spun nylon) significantly increased the sc hydration level. These three fabrics and the natural fiber fabrics had comparable wetted moisture content.


1997 ◽  
Vol 67 (12) ◽  
pp. 926-931 ◽  
Author(s):  
Kathryn L. Hatch ◽  
Harriet H. Prato ◽  
S. Haig Zeronian ◽  
Howard I. Maibach

Materials placed over human skin may change the stratum corneum (sc) hydration level, an important phenomenon because increases in normal levels of sc hydration pose potential health problems. This study examines the relationship between fabric moisture content and level of sc hydration so that the role of fabric moisture on sc hydration may be better understood. Three fabric/moisture treatments are placed on the sc—3.5-denier polyester fabric with an initial moisture content of 35% and cotton fabrics with either 44% or 75% initial moisture content—then covered with an occlusive dome. sc evaporative water loss (ewl) is measured before treatment placement and after 30 and 60 minutes of contact. The amount of moisture in the fabric at time of removal is calculated two different ways, and three analyses of variance are done using the evaporative water loss and two fabric final moisture content data sets. The rate of ewl is significantly higher after 30 minutes of treatment contact with sc than after 60 minutes of contact. The amount of moisture in the fabrics is significantly less at time 60 than at time 30, implying that the sc is more hydrated at 30 minutes than at 60 minutes. However, the fabrics contain less moisture when removed at 60 minutes than at 30 minutes. As fabric moisture content decreases, sc hydration decreases. The question we are not able to answer is “Where does the moisture go that is initially in the fabric?’


Cosmetics ◽  
2021 ◽  
Vol 8 (3) ◽  
pp. 83
Author(s):  
Hisae Aoshima ◽  
Rinta Ibuki ◽  
Masayuki Ito ◽  
Hirokazu Kawagishi

A clinical study was conducted to evaluate the efficacy of 2-aza-8-oxohypoxanthine (AOH) on human skin in a double-blind, placebo-controlled, and split-face comparative trial. To this end, a topical lotion containing 0.1% of AOH and its placebo formulation were applied in 20 Japanese subjects (age: 41–58 years, average: 48.4 ± 4.7 years) to their faces daily for eight weeks. The moisture content in the stratum corneum and the trans-epidermal water loss (TEWL) were measured at the beginning of the study and after eight weeks. The results obtained upon comparing the data of the two measuring points showed that the 0.1% AOH lotion caused a statistically significant larger decrease in TEWL after eight weeks. Moreover, the 0.1% AOH lotion produced a larger increase in the moisture content in the stratum corneum after eight weeks, although there was no statistical difference between the two formulations. These results clearly indicate that AOH is effective as a cosmetic agent with a skin barrier function against water loss.


1986 ◽  
Vol 8 (6) ◽  
pp. 289-292 ◽  
Author(s):  
S. DIKSTEIN ◽  
M. KATZ ◽  
A. ZLOTOGORSKI ◽  
Y. BROUN ◽  
D. WILSON ◽  
...  

1993 ◽  
Vol 18 (5-6) ◽  
pp. 421-427 ◽  
Author(s):  
Nancy L. Markee ◽  
Kathryn L. Hatch ◽  
Harriet H. Prato ◽  
S.Haig Zeronian ◽  
Howard I. Maibach

1992 ◽  
Vol 62 (11) ◽  
pp. 638-647 ◽  
Author(s):  
Kathryn L. Hatch ◽  
Nancy L. Markee ◽  
Harriet H. Prato ◽  
S. Haig Zeronian ◽  
Howard I. Maibach ◽  
...  

Fabric placed over human skin may change the stratum corneum (SC) hydration level, an important phenomenon because increases in normal levels of SC hydration pose potential health problems. The skin becomes more susceptible to abrasive damage, increases in permeability, and is more prone to microbial growth. The purpose of this study was to determine the effect of fiber type and fabric moisture content on SC hydration. Using three similarly constructed knit fabrics, six fabric type/moisture content combinations were selected for the tests. Using an occluded plastic dome, fabric samples were placed on both “normal” and “hydrated” volar forearm skin of subjects for a specified time period, then removed. Two minutes after removal, evaporative water loss and skin temperature were measured. The design of the study was a randomized complete block with all possible treatment combinations applied to each subject. Data were analyzed using analyses of variance on the linear and quadratic coefficients of best fit lines and Bonferroni t tests. For “normal” skin, SC hydration generally increased as fabric moisture content increased. The SC was significantly drier after being in contact with cotton fabric at regain than at the two moisture content levels above regain, and also under polyester fabric. For hydrated skin, the hydration state was significantly lower under the cotton fabric at regain than at 38.6% moisture content and at saturation, but was not significantly different under the polyester fabric at regain and at saturation.


2009 ◽  
Vol 56 (3) ◽  
pp. 137-145 ◽  
Author(s):  
Hiroki Ohara ◽  
Kyoko Ito ◽  
Hiroyuki Iida ◽  
Hitoshi Matsumoto

2021 ◽  
Vol 34 (3) ◽  
pp. 115-127
Author(s):  
Miho Miyanaga ◽  
Taro Uchiyama ◽  
Akira Motoyama ◽  
Nobuhiko Ochiai ◽  
Osamu Ueda ◽  
...  

<b><i>Introduction:</i></b> We aimed to investigate the effect of orally ingested collagen peptides (CPs) on skin condition and elucidate their mechanism of action. <b><i>Methods:</i></b> A randomized, placebo-controlled, double-blind trial was conducted in 99 healthy Japanese women, aged 35–50 years. The subjects were randomized into 3 groups (33 subjects/group) to receive 1 or 5 g of CP or placebo once daily for 12 weeks. Skin water content, transepidermal water loss (TEWL), skin elasticity, and skin thickness were evaluated before treatment and after 4, 8, and 12 weeks of treatment. The level of natural moisturizing factor (NMF) constituents in the stratum corneum (SC) was quantified before treatment and after 12 weeks of treatment. <b><i>Results:</i></b> Oral ingestion of CP increased the water content in the SC and epidermis and decreased TEWL. Furthermore, the NMF level in the SC was increased. However, skin elasticity and skin thickness remained unchanged. <b><i>Conclusions:</i></b> The improvement in skin water content following the oral ingestion of CP can be attributed to an increase in the level of NMF in the SC. <b><i>Trial Registration:</i></b> UMIN000030375 (retrospectively registered).


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