scholarly journals Nasal Spray Vaccines – A Breath of Immunity: An Interview with Dr. Marc-André Langlois

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Zacharie Saint-Georges ◽  
Omar Dewidar
Keyword(s):  
Nasal Spray ◽  
Health Research ◽  
Cutting Edge ◽  
Intrinsic Immunity ◽  
Molecular Virology ◽  
Canada Research Chair ◽  
The University

Dr. Marc-André Langlois, a cutting-edge virologist, Canada Research Chair in Molecular Virology and Intrinsic Immunity, and Professor in the Department of Biochemistry, Microbiology and Immunology at the University of Ottawa, received 1 million dollars in Canadian Institutes of Health Research (CIHR) funding to develop a nasal spray COVID-19 vaccine. We had the privilege of meeting with him virtually and having a fascinating and informative conversation on the COVID-19 pandemic, vaccines, and its effect on society.

Decolonizing Anthropology

2018 ◽  
Vol 36 (2) ◽  
pp. 53-72 ◽  
Author(s):  
Heidi Mogstad ◽  
Lee-Shan Tse
Keyword(s):  
Cutting Edge ◽  
Epistemic Justice ◽  
The University ◽  
Critical Reflections

This article has grown out of ongoing conversations, critical reflections and practical attempts at decolonizing anthropology at Cambridge. We begin with a brief account of recent efforts to decolonize the curriculum in our department. We then consider a few key thematic debates relating to the project of decolonizing the curriculum. First, we interrogate some consequences of how the anthropological ‘canon’ is framed, taught and approached. Second, we ask how decolonizing the curriculum might subtend a broader project towards epistemic justice in the discipline and the university at large. Third, we reflect on the necessity of locating ethics and methodology at the heart of ongoing conversations about anthropology and decoloniality. We conclude by reflecting on the affective tensions that have precipitated out of debate about the ‘uncomfortable’ relationship between anthropologists as intellectual producers at the ‘cutting edge’ of the canon, and the discipline’s rife colonial residues.

scholarly journals Music and the cutting edge of cultural expression

post(s) ◽  
2018 ◽  
Vol 4 ◽  
Author(s):  
Juan Pablo Viteri
Keyword(s):  
Popular Music ◽  
Copyright Law ◽  
Cutting Edge ◽  
Communication Studies ◽  
University Of Iowa ◽  
Prolific Author ◽  
Cultural Expression ◽  
Independent Media ◽  
The University

In this interview, Juan Pablo Viteri speaks with Kembrew McLeod. McLeod is a Professor of Communication Studies at the University of Iowa and an independent documentary producer. A prolific author and filmmaker, he has written and produced several books and documentaries that focus on popular music, independent media and copyright law.

scholarly journals Structured lifestyle education for people with schizophrenia, schizoaffective disorder and first-episode psychosis (STEPWISE): randomised controlled trial

2018 ◽  
Vol 214 (2) ◽  
pp. 63-73 ◽  
Author(s):  
Richard I. G. Holt ◽  
Rebecca Gossage-Worrall ◽  
Daniel Hind ◽  
Michael J. Bradburn ◽  
Paul McCrone ◽  
...  
Keyword(s):  
Mental Health ◽  
Physical Activity ◽  
Health Research ◽  
Controlled Trial ◽  
First Episode Psychosis ◽  
First Episode ◽  
Episode Psychosis ◽  
Randomised Controlled ◽  
The University ◽  
Lifestyle Education

BackgroundObesity is a major challenge for people with schizophrenia.AimsWe assessed whether STEPWISE, a theory-based, group structured lifestyle education programme could support weight reduction in people with schizophrenia.MethodIn this randomised controlled trial (study registration: ISRCTN19447796), we recruited adults with schizophrenia, schizoaffective disorder or first-episode psychosis from ten mental health organisations in England. Participants were randomly allocated to the STEPWISE intervention or treatment as usual. The 12-month intervention comprised four 2.5 h weekly group sessions, followed by 2-weekly maintenance contact and group sessions at 4, 7 and 10 months. The primary outcome was weight change after 12 months. Key secondary outcomes included diet, physical activity, biomedical measures and patient-related outcome measures. Cost-effectiveness was assessed and a mixed-methods process evaluation was included.ResultsBetween 10 March 2015 and 31 March 2016, we recruited 414 people (intervention 208, usual care 206) with 341 (84.4%) participants completing the trial. At 12 months, weight reduction did not differ between groups (mean difference 0.0 kg, 95% CI −1.6 to 1.7, P = 0.963); physical activity, dietary intake and biochemical measures were unchanged. STEPWISE was well-received by participants and facilitators. The healthcare perspective incremental cost-effectiveness ratio was £246 921 per quality-adjusted life-year gained.ConclusionsParticipants were successfully recruited and retained, indicating a strong interest in weight interventions; however, the STEPWISE intervention was neither clinically nor cost-effective. Further research is needed to determine how to manage overweight and obesity in people with schizophrenia.Declaration of interestR.I.G.H. received fees for lecturing, consultancy work and attendance at conferences from the following: Boehringer Ingelheim, Eli Lilly, Janssen, Lundbeck, Novo Nordisk, Novartis, Otsuka, Sanofi, Sunovion, Takeda, MSD. M.J.D. reports personal fees from Novo Nordisk, Sanofi-Aventis, Lilly, Merck Sharp & Dohme, Boehringer Ingelheim, AstraZeneca, Janssen, Servier, Mitsubishi Tanabe Pharma Corporation, Takeda Pharmaceuticals International Inc.; and, grants from Novo Nordisk, Sanofi-Aventis, Lilly, Boehringer Ingelheim, Janssen. K.K. has received fees for consultancy and speaker for Novartis, Novo Nordisk, Sanofi-Aventis, Lilly, Servier and Merck Sharp & Dohme. He has received grants in support of investigator and investigator-initiated trials from Novartis, Novo Nordisk, Sanofi-Aventis, Lilly, Pfizer, Boehringer Ingelheim and Merck Sharp & Dohme. K.K. has received funds for research, honoraria for speaking at meetings and has served on advisory boards for Lilly, Sanofi-Aventis, Merck Sharp & Dohme and Novo Nordisk. D.Sh. is expert advisor to the NICE Centre for guidelines; board member of the National Collaborating Centre for Mental Health (NCCMH); clinical advisor (paid consultancy basis) to National Clinical Audit of Psychosis (NCAP); views are personal and not those of NICE, NCCMH or NCAP. J.P. received personal fees for involvement in the study from a National Institute for Health Research (NIHR) grant. M.E.C. and Y.D. report grants from NIHR Health Technology Assessment, during the conduct of the study; and The Leicester Diabetes Centre, an organisation (employer) jointly hosted by an NHS Hospital Trust and the University of Leicester and who is holder (through the University of Leicester) of the copyright of the STEPWISE programme and of the DESMOND suite of programmes, training and intervention fidelity framework that were used in this study. S.R. has received honorarium from Lundbeck for lecturing. F.G. reports personal fees from Otsuka and Lundbeck, personal fees and non-financial support from Sunovion, outside the submitted work; and has a family member with professional links to Lilly and GSK, including shares. F.G. is in part funded by the National Institute for Health Research Collaboration for Leadership in Applied Health Research & Care Funding scheme, by the Maudsley Charity and by the Stanley Medical Research Institute and is supported by the by the Biomedical Research Centre at South London and Maudsley NHS Foundation Trust and King's College London.

Factors that influence the movement of Cauliflower mosaic virus in susceptible and resistant plants

2018 ◽  
Author(s):  
◽  
Mustafa Ali Adhab
Keyword(s):  
Mosaic Virus ◽  
Cell Movement ◽  
Aphid Transmission ◽  
Cauliflower Mosaic Virus ◽  
Lipaphis Erysimi ◽  
University Of Missouri ◽  
Molecular Virology ◽  
Different Strains ◽  
The University ◽  
Virus Survival

[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Since the first description of Cauliflower mosaic virus (CaMV), it has been the subject of many research papers, both as a model system for plant molecular virology and for the diseases it causes in major winter crops. CaMV has been associated with a number of ground-breaking papers. Movement through the plant is a necessary step for virus survival. For this reason, each viral protein is likely to interact with multiple host factors. Inactivation of one or more of these multiple interactions could lead to a delay in viral movement. The 40 kDa CaMV P1 movement protein (P1) is an essential protein in CaMV cell-to-cell movement. A CaMV mutant virus that contained a non-functional gene I coding sequence was not able to cause a systematic infection in plants, but the accumulation of encapsidated forms of virion DNA could still be detected, which indicated that P1 is not involved in CaMV replication. Upon transient expression in plant protoplasts, the P1 protein alone is sufficient to cause the formation of tubular extensions projecting out of the cell membrane. Furthermore, P1 is also able to induce the formation of tubules in whole leaves upon agroinfiltration into Nicotiana benthamiana leaves. ... Aphid transmission is essential for CaMV spread in nature. Previous studies have shown that the degree of aphid preference for virus-infected plants can alter the progress of virus epidemics. I tested whether infection of turnip plants (Brassica rapa L. var. rapa) with different strains of CaMV can influence turnip aphids’ (Lipaphis erysimi) choice of host. Three different strains of CaMV that cause different types of symptoms on turnips were used in this study. These strains were NY8153 (severe), W260 (mild) and H12 (symptomless). I found that turnip aphids preferred W260-infected plants more than NY8153-, H12-infected or healthy plants. I concluded that aphids can recognize different strains of CaMV and will choose plants with specific strains over others; specifically aphids prefer W260-infected turnips over other choices. These results suggest that virus infection affects the aphid host choice and this in turn may have implications for the spread of different virus strains.

scholarly journals 2520

2017 ◽  
Vol 1 (S1) ◽  
pp. 82-82
Author(s):  
Meghan Spiroff ◽  
Lisa Connally ◽  
Anita Johnson ◽  
Aalap Doshi ◽  
Patricia Piechowski
Keyword(s):  
Clinical Trials ◽  
Best Practices ◽  
Health Research ◽  
Participant Recruitment ◽  
Gender And Age ◽  
Study Population ◽  
Gender And Age Differences ◽  
The University ◽  
Racial Ethnic ◽  
Research Studies

OBJECTIVES/SPECIFIC AIMS: Across the Clinical and Translational Science Award (CTSA) Consortium, participant recruitment into clinical trials is essential to advance science. Without proper participant recruitment, clinical trials do not result in gains in scientific knowledge, wastes time, funds, and other resources (Mahon et al., 2015). METHODS/STUDY POPULATION: Participant recruitment programs across the consortium are inconsistent in staffing, program services, and program goals. The participant recruitment program at the University of Michigan’s (U-M) Michigan Institute for Clinical & Health Research (MICHR) provides expertise, tools, and resources to facilitate participant recruitment in clinical and health research studies. RESULTS/ANTICIPATED RESULTS: We will explain our program infrastructure, staffing, services, and discuss how we maintain an engaged registry with over 27,000 participants interested in research studies at U-M. DISCUSSION/SIGNIFICANCE OF IMPACT: Proper recruitment into clinical trials results in findings that are relevant for genetic, cultural, linguistic, racial/ethnic, gender, and age differences (Cottler et al., 2013). We hope to share our best practices that aid in the development and success of participant recruitment across the CTSA Consortium.

Molecular virology teaching at the university of Strasbourg

Virologie ◽  
2018 ◽  
Vol 22 (4) ◽  
pp. 226-228
Author(s):  
David Gilmer
Keyword(s):  
Molecular Virology ◽  
The University

Western Faculty Profile: Dr. Martin Houde

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Brandon Lieng
Keyword(s):  
Star Formation ◽  
Work Experience ◽  
Full Professor ◽  
First Year ◽  
California Institute ◽  
Physical Processes ◽  
California Institute Of Technology ◽  
Canada Research Chair ◽  
Institute Of Technology ◽  
The University

Dr. Martin Houde is a Full Professor with the Department of Physics and Astronomy at Western University. With experience at the California Institute of Technology’s Submillimeter Observatory in Hawaii and three degrees from the University of Montréal, Dr. Houde brings his wealth of knowledge in the fields of star formation, extraterrestrial chemistry, and astrophysical instrumentation to Western. His research focuses on how the interactions between basic physical processes like magnetism and chemical reactions lead to the formation of stars while experience from the California Institute of Technology allows Dr. Houde to continually develop and enhance astrophysical instrumentation that enables researchers to further explore what lies beyond our galaxy. He is also the Canada Research Chair in Star Formation and teaches courses in Physics and Astronomy at Western. Brandon Lieng, First Year Representative with WURJHNS, interviewed Dr. Houde to learn more about his background, work, experience, and insights on the field of research.

Sign in / Sign up

Export Citation Format

Share Document