scholarly journals Study and management of type-2 diabetes mellitus in patients with hypertension at tertiary care hospital

Author(s):  
B. V. Nagarjuna Yadav ◽  
Shaik Tasleem ◽  
Shaik Zaheer Basha ◽  
Vanipenta Vinay Kumar ◽  
Vedururu Sai Harsha Vardhini

Background: This study was aimed to study and management of hypertension in diabetic patients.Methods: A prospective, observational study was conducted in 160 diabetic hypertensive patients admitted in general medicine wards at Andhra Pradesh Vaidya Vidhana Parishad Hospital, (APVVP), Proddatur. Patients who signed informed consent form were only included in the study. All the data were recorded from patients’ case files and analyzed.Results: Of enrolled 160 patients, 86 (53.75%) were female and 74 (46.25%) were male and maximum number of the patients 32.5% were found in the age group of 60-69 years. Out of 160 admitted patients, (51) patients treated with metformin, glibenclamide and atenolol, (18) patients treated with metformin, glimiperide, and amlodipine, (6) patients treated with metformin and amlodipine, (28) patients treated with metformin, glimiperide and atenolol, (19) patients treated with metformin and atenolol, (17) patients treated with metformin, glibenclamide and amlodipine,(9) patients treated with metformin, glibenclamide and losartan, (5) patients treated with metformin and losartan, (7) patients treated with metformin, glimiperide, and losartan.Conclusions: There was less awareness among the patients regarding the control of type-2 diabetes mellitus with hypertension. Majority of diabetic patients noticed with hypertension and β adrenergic blockers remained first choice of drug for hypertension in diabetes. Calcium channel blockers were also prescribed to many patients and were successful to achieve target blood pressure. Among anti-diabetic drugs, biguanides were most frequently prescribed class of drugs. Metformin was the most prescribed drug and Sulphonyl urea were the next most prescribed class of drug.

Author(s):  
Abhishek Kamendu ◽  
Ahmad Nadeem Aslami

Background: Diabetes has become a major health challenge all over the world. Previous studies have found that diabetes and thyroid disorders mutually influence each other and both disorders tend to coexist. The aim of this study was to find out prevalence of hypothyroidism and its associated factors in type 2 diabetes mellitus patients.Methods: Consecutive 200 patients with type 2 diabetes mellitus attending outpatient department of medicine in a tertiary care centre in Sasaram, Bihar were evaluated clinically and biochemically. Subclinical hypothyroid and overt hypothyroidism was diagnosed as per standard definitions. The results obtained were statistically analysed by using chi square test and finding odds ratio.Results: Out of 200 patients, 75.5% were euthyroid while 24.5% were hypothyroid. Out of 49 hypothyroid patients, subclinical hypothyroid (SC-Hypo) was present in 41 patients and overt hypothyroid (C-Hypo) was present in only 8 patients. The prevalence of hypothyroidism was found more in males, age ≥60 years, patients with HbA1c value ≥7%, patients with diabetes duration less than 5 years and in hypertensive patients.Conclusions: Thyroid dysfunction screening should be done in all type 2 diabetic patients periodically and appropriate individualized treatments in addition to thyroid function test should be given to diabetes mellitus patients with subclinical hypothyroidism as well.


2021 ◽  
Vol 8 (6) ◽  
pp. 800
Author(s):  
Shubhangi Verma ◽  
Sohail Sheikh

Background: Anaemia and type 2 diabetes mellitus are two sides of a coin affecting the quality of life of the patients. Anaemia associated with diabetic status of the patients disturbs the exercise capacity, increases fatigue, anorexia, depression, cognitive dysfunction and decreased libido. Hence, we conducted a study to find the prevalence of anaemia among patients with type 2 diabetic patients and its correlation with glycosylated haemoglobin.Methods: An observational study was conducted in the department of medicine in a tertiary care hospital in Maharashtra. The data was collected from patients with type 2 diabetes attending the outpatient department during a span of 5 months (September 2020 to February 2021). The patients with pre-existing hypertension, chronic renal failure, congestive cardiac failure, stroke and other haematological disorders were excluded from the study. Patients on hormonal therapy, pregnant and lactating patients were also excluded from the study. Prior to the start of the study necessary permissions were taken from the institutional ethics committee. Relevant statistics were used to analyse the data.Results: The prevalence of anaemia in the present study was 45 (56.25%). Among these 45 patients 37 patients had normocytic normochromic anaemia, 6 cases of microcytic hypochromic anaemia and 2 cases of macrocytic anaemia. The mean haemoglobin levels among patients with Hba1c more than 7% was 9.7±1.12 and among Hba1c less than 7% was 12. 23±1.08 and this difference was statistically significant.Conclusions: About half of the patients were anaemic in the present study. Normochromic normocytic anaemia was the most common type of anaemia. There was significant association with levels of anaemia with Hb1ac in the present study.


2020 ◽  
Vol 7 (6) ◽  
pp. 983
Author(s):  
Prakash Ranjan ◽  
Jayanta K. Das

Background: The prevalence of stress and anxiety in diabetes is considerably higher than normal population and found to have a negative impact on diabetes. The aim of this study was to examine the relationships among perceived diabetes-related stress and anxiety behaviors in adults living with type 2 diabetes (T2DM).Methods: In this descriptive and cross sectional study, systematic random sampling technique was used to select the sample of type 2 diabetic patients. Scheduled interview of 412 type 2 diabetic patient was conducted at outpatient department of a tertiary care hospital in New Delhi.Results: Out of 412 diabetic patients, 58.7 percent feel diabetes-related stress and anxiety behaviors when they think about living with diabetes. Age of patients, educational status, occupation and average monthly family income of diabetic patients are statistically associated with perceived diabetes-related stress and anxiety behaviors of type 2 diabetes mellitus patients. Lifestyle behaviour like diet pattern (vegetarian or nonvegetarian diet) and moderate intensity activities like walking are also statistically associated with perceived diabetes-related stress and anxiety behaviors of type 2 diabetes mellitus patients.Conclusions: This study found a high prevalence of diabetes-related stress and anxiety behavior in patients with Type 2 DM. Therefore, the care of individuals with type 2 Diabetes Mellitus (DM) should include the screening and possible management of stress and anxiety in order to achieve and sustain treatment goals.


Author(s):  
PRUDENCE A. RODRIGUES ◽  
DAWN TESLIN DAMIEN ◽  
MARY CECIL K. T. ◽  
NARESH KUMAR M. ◽  
RESHMA S. S. ◽  
...  

Objective: The objective of this study is to evaluate prescribing pattern, analyze drug-related problems, identify co-morbidities and complications in Type 2 Diabetes Mellitus patients and also to perform cost analysis of Biguanides, Sulfonylureas, Dipeptidyl Peptidase Inhibitors Methods: A Prospective observational study was done in General Medicine and Endocrinology Departments of PSG Hospitals. A total of 200 study subjects, including both inpatients and outpatients, above 18 y of age, prescribed with OHAs (Biguanides, Sulfonylureas and DPP4 inhibitors) were included in the study. Results: Diabetes was more prevalent among males. OHAs were most prescribed in the age group of 51-60 y. Hypertension (71%) was the most common comorbidity and Diabetic neuropathy (23%) was the most common complication found in the patients. Multidrug therapy (72.5%) was most prescribed in diabetic patients, followed by Biguanides. Hypoglycemia was the most prevalent ADR. Cost analysis showed that T. Linagliptin was of high cost and T. Glimepiride being the low cost. Using WHO core indicators prescribing patterns were assessed. Feedback was collected and results were reported to the physicians which showed rational utilization of drugs. Conclusion: The study on drug utilization conducted in a tertiary care hospital helped us to find out that prescribing trends seems to be progressing towards combination therapy, predominantly two-drug therapy


2021 ◽  
Vol 8 (37) ◽  
pp. 3334-3338
Author(s):  
Satish Kumar

BACKGROUND Type 2 diabetes mellitus is common in the Indian population and awareness regarding the disease and its complications is low among the patients with diabetes. There is lack of studies regarding awareness of complications of diabetes among type 2 diabetic patients. The purpose of this study was to assess the awareness of diabetic complications among type 2 diabetic patients. METHODS This is an institutional based observational study. The sample comprised of 150 adult patients with type 2 diabetes mellitus who underwent treatment in the Department of Medicine, Medical College Kottayam and the patient’s age ranged from 18 - 77 years. RESULTS Majority of patients were in the age group 38 to 57 and the sample comprised of 56 % males and 44 % female patients. Out of 150 patients involved in the study, 120 patients (80 %) were aware of the complications of diabetes mellitus. Among the male patients, 70 (83.33 %) and among females, 50 (75.75 %) were aware of the complications in diabetes. In the study sample, 92 (61.33 %) were aware of the foot problems, 120 patients (80 %) were aware of renal complications, 91 patients were aware regarding eye problems of diabetes, 38 (25.33 %) regarding development of hypertension, 62 (41.33 %) regarding heart attack, 42 (28 %) patients were aware regarding development of stroke and 78 patients (52 %) had awareness regarding occurrence of recurrent infections. CONCLUSIONS Awareness regarding diabetes and its complications is fairly good among the diabetic patients in Kerala. Awareness regarding all complications of diabetes was higher among males than females. Providing awareness to type 2 diabetic patients by various educational programs may be of further help to prevent complications and to decrease the mortality and morbidity in type 2 diabetes patients. KEYWORDS Awareness, Diabetes


2021 ◽  
pp. 6-8
Author(s):  
Yash Salil Patel

Microvascular complications of Type 2 Diabetes Mellitus (T2DM), (retinopathy and nephropathy) have a similar etiopathogenetic mechanism besides genetic predisposition. Even though these two complications frequently co-exist, their frequency varies. The association of these two signicant complications and their coexistence needs a relook. To study prevalence of retinopathy and nephropathy in Type 2 diabetes mel Aim: litus. Comparison of diabetic retinopathy and nephropathy in Type 2 diabetes mellitus and its correlation of diabetic retinopathy and nephropathy with duration of illness and various risk factors that affects development, progression and severity of diabetic retinopathy and nephropathy. 100 diabetic patients were taken up for study for a period of one year meeti Methodology: ng the criteria for the present study. Detailed history was taken from patient and meticulous examination was done of all patients with special emphasis on renal and ophthalmic symptoms. Clinical data and investigation prole was tabulated. Statistical analysis was done. Among 100 patients, 22 had diabetic retinopathy. Among patients with diab Results & Conclusion: etic retinopathy, 68.18% patients had positive family history. Among 100 patients, 32 had diabetic nephropathy, mean FBS was 207 mg%, PPBS was 317.8 mg% and mean HbA was 9.2%. Among patients with diabetic retinopathy, mean FBS was 211 mg%, PPBS was 324.9 1c mg%, HbA was 9.5%. From this study it is found that diabetic nephropathy starts earlier than retinopathy. In this study 1c hypertension was found to accelerate progression into nephropathy and retinopathy.


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