scholarly journals Intravenous ondansetron induced hypersensitivity reaction: a case report

Author(s):  
S. Nitya ◽  
M. Shanthi ◽  
R. Meenakshi ◽  
S. Kiruthika

Ondansetron a selective 5-HT3 receptor antagonist has been widely used as a prophylactic antiemetic for chemotherapy induced and anaesthesia related nausea and vomiting. Anaphylaxis and anaphylactoid reaction rarely occur in less than 1% of the patients and may lead to potentially life-threatening events. This study is one such rare case report of hypersensitivity reaction to intravenous ondansetron in a perioperative setting. Familiarity about anaphylactoid reactions to intravenous ondansetron among the health practitioners would help them to bring about a rational approach to decrease its incidence.

2019 ◽  
Vol 10 (9) ◽  
pp. 1617
Author(s):  
Harsh Mohan Pathak ◽  
Sobhan Mishra ◽  
Neeta Mohanty ◽  
Sanchari Sinha Roy ◽  
Satchidananda Meher

Author(s):  
Smriti Sharma ◽  
Upma . ◽  
Deep Mani

Idiopathic aplastic anemia is a pancytopenia disorder that is a rare but life threatening for both mother and fetus during pregnancy. Association of aplastic anemia with pregnancy is unclear but considered to be interrelated. Bone marrow transplantation is the most effective treatment for adult aplastic anemia but is inadvisable to perform during pregnancy because of the teratogenic effect of immunosuppressive agents or radiation therapy to the growing fetus. Supportive care, withdrawal from offending drugs and involving erythrocytes and platelets transfusion is a promising way to save the life. Here author present a case report of 36-year-old lady with idiopathy aplastic anemia. In this case medical investigation revealed severe anemia of unknown origin. The patient was treated with hematinics, blood transfusion and glucocorticoids. A healthy baby was delivered without evidence of hemolysis at her eight month and one week of pregnancy, the patient recovered and discharged with normal incidence. Being a rare case, it becomes a necessity to report such life-threatening disorder and management. Moreover, to our knowledge this is the first case reported of its kind from Jammu and Kashmir Division of India.


Author(s):  
Krishan Sarna ◽  
Martin Kamau ◽  
Symon Guthua

Lesions involving the tongue may present with life threatening complications such as airway compromise and risk of severe hemorrhage. This paper reports the surgical management of a non-involuting massive congenital hemangioma of the tongue in an infant presenting with difficulty breathing, feeding and inability to close the mouth.


Author(s):  
Anant Gopal Nigam ◽  
Ankita Beniwal ◽  
Shefali Chaturvedi ◽  
Tanmay Bhatt

ABSTRACT Eugenol is a phenolic compound commonly used in dentistry as an analgesic and anti-inflammatory drug. Zinc oxide eugenol is an important root canal filling material in primary teeth with excellent documented success. Its cytotoxic effect is documented in some cases due to production of zinc eugenolate which is highly unstable and induces type IV hypersensitivity reactions and even generalized anaphylactic symptoms. But, the case reports documenting immediate hypersensitivity reaction to eugenol are very rare. This was a case of type I immediate hypersensitivity reaction to eugenol in a 3 years old pediatric patient. During the full mouth rehabilitation under general anesthesia, hard indurated swelling of lower lip was observed at the time of obturation of mandibular primary teeth. The procedure was stopped immediately suspecting an allergic response which was later confirmed to be eugenol allergy by patch test. Hence, it is important to evaluate all local allergies even if the patient fails to report allergy history. How to cite this article Beniwal A, Chaturvedi S, Bhatt T, Sharma A, Nigam AG. Eugenol Hypersensitivity in Pediatric Dental Patient: A Rare Case Report. J Mahatma Gandhi Univ Med Sci Tech 2016;1(2):68-70.


2016 ◽  
Vol 04 (12) ◽  
pp. E1244-E1246 ◽  
Author(s):  
Piero Valli ◽  
Carlo Valli ◽  
Thomas Pfammatter ◽  
Peter Bauerfeind

2011 ◽  
Vol 2011 ◽  
pp. 1-3 ◽  
Author(s):  
Neha Thakur ◽  
Ravitanaya Sodani ◽  
J. Chandra ◽  
Deonath Mahto

Malaria remains an overwhelming problem in the tropical developing countries, with 300 to 500 million new cases and about a million deaths per year (Mishra et al., 2003). Malaria is a potentially life-threatening disease in the tropics. Jaundice is one of the severe manifestations offalciparummalaria. Its incidence (Mishra et al., 2003). varies between 10 and 45% in different reports and is seen more in adults than in children. Jaundice may vary from mild to very severe. However, clinical signs of hepatic encephalopathy (such as liver flaps) are never seen unless there is presence of concomitant viral hepatitis (WHO, 2000). Our case is a 6-year-old female child presented with fever, jaundice, and anasarca. Peripheral smear showed trophozoites and schizonts ofPlasmodium(P.)vivaxand trophozoites and gametocytes ofP. falciparum.Viral markers for hepatitis were negative. She developed fulminant hepatic failure and expired after 26 hours of admission.


2015 ◽  
Vol 3 (2) ◽  
pp. 72-73
Author(s):  
N.S. Neki ◽  
Ankur Jain ◽  
Rohit Bajaji ◽  
Mohit Manav Jindal

Hair dye poisoning is not uncommon but an emerging entity in India with increased morbidity and mortality. The main component of hair dye poisoning is paraphenylenediamine (PPD), which is highly toxic thus making it life threatening. PPD poisoning can result in various toxic effects, multiorgan failure and ultimately death. Clinical suspicion and timely management can improve the outcome. We report a case of 35 year old male presented to hospital within 4 hours of consuming hair dye with complaints of swelling of face and neck, vomiting and difficulty in breathing. He was satisfactorily managed with supportive therapy and endotracheal intubation and discharged without any ill effects.Journal of Advances in Internal Medicine 2014;3(2):72-73


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