scholarly journals Androgenic alopecia in post-menopausal female: a clinical presentation

Author(s):  
Kirty Nahar ◽  
Usha Bohra ◽  
Vivek Arya

Androgenic alopecia is a patterned hair loss occurring due to systemic androgens and genetic factors. It is the most common cause of hair loss in both genders. The appearance of this condition is the cause of significant stress and psychological problems, making appropriate management important. A 68-year-old postmenopausal female presented with complaints of increased hair loss from scalp, excessive hair growth at undesired sites and hirsutism not corrected with medications. On thorough investigations, CT scan whole abdomen and endocrinological workup, a clinical diagnosis of alopecia and hirsutism due to hyperandrogenemia secondary to ovarian tumor made. Abdominal hysterectomy with B/L salpingo-oophorectomy was done. Histopathological examination revealed an encapsulated tumor in right ovary-sex cord stromal tumor consistent with Leydig cell tumor in right ovary, no evidence of malignancy. Left ovary was normal. Patient showed significant regression of clinical signs and symptoms on follow up after 1 month. All women with severe hirsutism or androgenic alopecia needs further work up to locate the source of androgen over production.

2008 ◽  
Vol 28 (4) ◽  
pp. 365-372 ◽  
Author(s):  
Sruthi Srinivasan ◽  
Elizabeth Joyce ◽  
Michelle Senchyna ◽  
Trefford Simpson ◽  
Lyndon Jones

2012 ◽  
Vol 87 (5) ◽  
pp. 789-790 ◽  
Author(s):  
Felipe Maurício Soeiro Sampaio ◽  
Fabrício Tinoco Lourenço ◽  
Daniel Lago Obadia ◽  
Leninha Valério do Nascimento

Male patient, 28 years old, presented with an asymptomatic yellowish erythematous papule on his right thigh. Excisional biopsy was performed for histopathological examination of the lesion. Multinucleated cells (Touton giant cells) were observed. S100 immunohistochemistry was negative for CD1a and positive for CD4 and CD68. Based on clinical and histopathological findings associated with immunohistochemistry, we concluded that it was a case of adult-type xanthogranuloma. Because it was a solitary lesion without other clinical signs and symptoms, the medical conduct adopted was patient orientation.


Author(s):  
Shruthi Ananthula ◽  
Ushadevi Gopalan

We report a case of a calcified submucous leiomyoma in 50 years women with lower abdominal discomfort. She had no previous history of surgery. Work up confirmed a calcified leiomyoma. The diagnosis was made by radiological findings. Total abdominal hysterectomy with bilateral salpingo-oophorectomy is the surgery of choice for these cases. Histopathological examination confirmed a calcified leiomyoma. A calcified leiomyoma in a post-menopausal woman is rare.


2019 ◽  
Vol 18 (4) ◽  
pp. 66-78
Author(s):  
A. Yu. Kugushev ◽  
A. V. Lopatin ◽  
S. A. Yasonov ◽  
D. V. Rogozhin

Cranial fasciitis (CF) is a rare benign lesion of the skull. Due to the rarity of this disease, prospective studies of it have not been conducted. The first description dedicated of the case of CF was in 1980. Later were descriptions of only clinical cases of observation and treatment of children with this pathology. For these reasons, questions regarding true incidence, genetic risk factors, prognosis and long-term still unanswered. Clinically, CF is represented by a dense, painless, growing mass on the scalp. Given the rarity of the occurrence of CF in differential diagnosis, it is usually not considered. In addition, there are no pathognomonic clinical signs and symptoms, and changes on MRI are often non-specific. Treatment involves removal of the tumor mass, after which a histopathological examination confirms the diagnosis of CF. As a rule, a good result is observed with complete resection, however, in this case it has to necessary to perform auto-bone grafting of the skull bone defect. CF is a rare and underexplored fibroproliferative disease. Because of its locally invasive nature and nonspecific manifestations of CF, it is often difficult to distinguish from malignant neoplasms and infections. Complete surgical removal is the best choice to make diagnosis and successful treatment. Parents gave their consent to use information about the child in the article.


Geriatrics ◽  
2021 ◽  
Vol 6 (1) ◽  
pp. 5
Author(s):  
Donatella Rita Petretto ◽  
Gian Pietro Carrogu ◽  
Luca Gaviano ◽  
Lorenzo Pili ◽  
Roberto Pili

Over 100 years ago, Alois Alzheimer presented the clinical signs and symptoms of what has been later called “Alzheimer Dementia” in a young woman whose name was Augustine Deter [...]


Pituitary ◽  
2020 ◽  
Author(s):  
Eliza B. Geer ◽  
Roberto Salvatori ◽  
Atanaska Elenkova ◽  
Maria Fleseriu ◽  
Rosario Pivonello ◽  
...  

The original version of the article unfortunately contained an error in the first name and the surname of one of the authors in the author group. The last author name was incorrectly published as ‘F. Pecori Giraldi’ and the corrected name is ‘Francesca Pecori Giraldi’ (First name: Francesca; Surname: Pecori Giraldi).


2016 ◽  
Vol 15 (2) ◽  
pp. 220-223 ◽  
Author(s):  
Shadi Saghafi ◽  
Reza Zare-Mahmoodabadi ◽  
Narges Ghazi ◽  
Mohammad Zargari

Objective: The purpose of this study was to retrospectively analyze the demographic characteristics of patients with central giant cell granulomas (CGCGs) and peripheral giant cell granulomas (PGCGs) in Iranian population.Methods: The data were obtained from records of 1019 patients with CGCG and PGCG of the jaws referred to our department between 1972 and 2010. This 38-year retrospective study was based on existing data. Information regarding age distribution, gender, location of the lesion and clinical signs and symptoms was documented. Results: A total of 1019 patients were affected GCGLs including 435 CGCGs and 584 PGCGs during the study. The mean age was 28.91 ± 18.16. PGCGs and CGCGs had a peak of occurrence in the first and second decade of life respectively. A female predominance was shown in CGCG cases (57.70%), whereas PGCGs were more frequent in males (50.85%). Five hundred and ninety-eight cases of all giant cell lesions (58.7 %) occurred in the mandible. Posterior mandible was the most frequent site for both CGCG and PGCG cases. The second most common site for PGCG was posterior maxilla (21%), whereas anterior mandible was involved in CGCG (19.45%). The majority of patients were asymptomatic. Conclusions: In contrast to most of previous studies PGCGs occur more common in the first decade and also more frequently in male patients. Although the CGCGs share some histopathologic similarities with PGCGs, differences in demographic features may be observed in different populations which may help in the diagnosis and management of these lesions.Bangladesh Journal of Medical Science Vol.15(2) 2016 p.220-223


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