Successful maternal and fetal outcome in an uncorrected case of tetralogy of fallot

Tetralogy of Fallot (ToF) is the most common congenital heart defect which is associated with systemic cyanosis. Pregnancy and delivery cause dramatic alterations in cardiovascular physiology and pregnancy in women with unrepaired TOF may have a worsening in right to left shunt with an increase of the cyanosis. This possesses an elevated risk of maternal and foetal morbidity and even mortality. We report and discuss a case of a 24 years old Primigravida with uncorrected ToF. A multidisciplinary team was involved in the management of the case with the aim to minimize maternal and foetal complications. The target of the management was to perform adequate maternal surveillance by maintaining an adequate oxygen saturation and good haemoglobin levels and perform timely foetal surveillance tests in the form of Obstetric doppler. A caesarean section was performed at 35 weeks and 5 days of gestation without any maternal or fetal complications. Without optimal obstetrical or medical management, prognosis of pregnancy in patient with uncorrected ToF is poor.

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Peripartum cardiomyopathy in uncorrected tetralogy of fallot: a case report

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20180207 ◽

2018 ◽

Vol 7 (2) ◽

pp. 748

Author(s):

Mukund Vasantrao Phutane ◽

Varsha Ansaram Kal ◽

Vishal Vijayrao Patil ◽

N. O. Bansal

Keyword(s):

New York ◽

Congenital Heart Disease ◽

Heart Disease ◽

Tetralogy Of Fallot ◽

Congenital Heart ◽

Heart Association ◽

Fetal Outcome ◽

Pregnancy And Delivery ◽

New York Heart Association ◽

Postpartum Cardiomyopathy

Tetralogy of Fallot (ToF) is the most common cyanotic congenital heart with incidence about 10% of all congenital heart disease. Natural survival to the fourth decade is extremely rare (only about 3%), but there is a tendency of increasing number of women with cyanotic congenital heart disease living 3 to 4 decades and are becoming pregnant. Because of significant physiology adaptation and changes, pregnancy and delivery process are troublesome for most unhealthy women, including those with uncorrected ToF. For ToF patients, it remains an important cause of maternal morbidity (62.5%), and even mortality (10%) and has significant effects on fetal outcome. Discussed below a case of pregnancy in a 30 year old woman with uncorrected ToF, dyspnoea class II of New York Heart Association, on 36th week pregnancy with complication of postpartum cardiomyopathy. Through dedicated medical care, patient's condition improvement can be seen. Prognosis of pregnancy in patient with uncorrected ToF is poor without optimal obstetrical and medical management.

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Ultra High-Resolution Gene Centric Genomic Structural Analysis of a Non-Syndromic Congenital Heart Defect, Tetralogy of Fallot

PLoS ONE ◽

10.1371/journal.pone.0087472 ◽

2014 ◽

Vol 9 (1) ◽

pp. e87472 ◽

Cited By ~ 9

Author(s):

Douglas C. Bittel ◽

Xin-Gang Zhou ◽

Nataliya Kibiryeva ◽

Stephanie Fiedler ◽

James E. O’Brien ◽

...

Keyword(s):

Structural Analysis ◽

High Resolution ◽

Tetralogy Of Fallot ◽

Congenital Heart Defect ◽

Congenital Heart ◽

Heart Defect

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Aortic Root Translocation for Repair of Transposition of Great Arteries With Absent Pulmonary Valve

World Journal for Pediatric and Congenital Heart Surgery ◽

10.1177/2150135118820865 ◽

2019 ◽

Vol 10 (4) ◽

pp. 513-514

Author(s):

Ashish Katewa ◽

Nishith Bhargava ◽

Balswaroop Sahu ◽

Atul Prabhu ◽

Shivani Gajpal

Keyword(s):

Ventricular Septal Defect ◽

Tetralogy Of Fallot ◽

Congenital Heart Defect ◽

Aortic Root ◽

Rare Case ◽

Congenital Heart ◽

Septal Defect ◽

Pulmonary Valve ◽

Absent Pulmonary Valve ◽

Transposition Of Great Arteries

Absent pulmonary valve is a rare congenital heart defect where the pulmonary valve is either absent or rudimentary. It is usually associated with tetralogy of Fallot although it has been reported with other lesions. We present a rare case of absent pulmonary valve associated with transposition of great arteries and non-routable ventricular septal defect that was surgically managed by aortic root translocation.

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OC26.03: Comparison of the prevalence of pathogenic copy number variation in tetralogy of Fallot and associated congenital heart defect diagnosed between fetuses and children

Ultrasound in Obstetrics and Gynecology ◽

10.1002/uog.19379 ◽

2018 ◽

Vol 52 ◽

pp. 61-61

Author(s):

T. Man ◽

X. Hao ◽

S. Ge ◽

Y. He

Keyword(s):

Copy Number Variation ◽

Tetralogy Of Fallot ◽

Congenital Heart Defect ◽

Copy Number ◽

Congenital Heart ◽

Heart Defect ◽

Number Variation

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EDUCATIONAL SERIES IN CONGENITAL HEART DISEASE: Tetralogy of Fallot: diagnosis to long-term follow-up

Echo Research and Practice ◽

10.1530/erp-18-0049 ◽

2019 ◽

Vol 6 (1) ◽

pp. R9-R23 ◽

Cited By ~ 1

Author(s):

R Bedair ◽

X Iriart

Keyword(s):

Congenital Heart Disease ◽

Early Childhood ◽

Heart Disease ◽

Tetralogy Of Fallot ◽

Congenital Heart Defect ◽

Congenital Heart ◽

Live Births ◽

Long Term Follow Up

Tetralogy of Fallot (TOF) is the most common cyanotic congenital heart defect, affecting 3 in 10,000 live births. Surgical correction in early childhood is associated with good outcomes, but lifelong follow-up is necessary to identify the long-term sequelae that may occur. This article will cover the diagnosis of TOF in childhood, the objectives of surveillance through adulthood and the value of multi-modality imaging in identifying and guiding timely surgical and percutaneous interventions.

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