scholarly journals Assessment of health related quality of life (HRQol) in patients with Meige’s syndrome

2018 ◽  
Vol 6 (6) ◽  
pp. 1956
Author(s):  
Alok Verma ◽  
Pavan Singh ◽  
Saurabh Agarwal ◽  
Babita Gupta
Keyword(s):  
Quality Of Life ◽  
Botulinum Toxin ◽  
Social Functioning ◽  
Bodily Pain ◽  
New Delhi ◽  
Health Related Quality ◽  
Moderate Depression ◽  
Related Quality ◽  
Health Related

Background: There is paucity of literature regarding health related quality of life (HRQoL) in Meige’s syndrome (MS) especially from India. This study assessed HRQoL in its global and disease specific aspect by previously validated instruments in patients with Meige’s syndrome.Methods: The study was performed in AIIMS, New Delhi. Subjects with Meige’s syndrome as well as age and gender matched healthy controls were enrolled from Movement Disorder and botulinum toxin clinic, Department of Neurology, AIIMS, New Delhi. Uneducated patient, those could not read questionnaires and cases who had received botulinum toxin within 6 months were excluded from the study.Results: A 14 pts of Meige’s syndrome were enrolled and 14 age matched controls were taken. All the pts of Meige’s syndrome scored worse in SF-36 as compared to controls in areas of role physical (p =0.002), bodily pain (p = 0.001), general health (p = <0.001), social functioning (p = 0.05) and role emotion (p = <0.001). 50% of patients with Meige’s syndrome had depression out of whom 21.4 % had moderate depression. Patients with Meige’s syndrome had significantly impaired scores in 10 of the 12 subscales which was profound in areas of ocular pain, near activities, distance activities, social functioning, role difficulties, dependency, driving, compared to borderline impairment in general vision, mental health, color vision.Conclusions: This study clearly demonstrated that pts with Meige’s syndrome, suffered from significant impairment in HRQoL as compared to controls. Higher proportion of patients with Meige’s syndrome suffered from moderate depression compared to their control. Pts with Meige’s syndrome had severe impairment of vision related quality of life. 

scholarly journals Assessment of health-related quality of life (HRQoL) in patients with spasmodic dysphonia

2018 ◽  
Vol 5 (4) ◽  
pp. 798
Author(s):  
Alok Verma ◽  
Babita Gupta ◽  
Saurabh Agarwal
Keyword(s):  
Quality Of Life ◽  
Botulinum Toxin ◽  
Spasmodic Dysphonia ◽  
New Delhi ◽  
Health Related Quality ◽  
Moderate Depression ◽  
Related Quality ◽  
Health Related ◽  
Disease Specific

Background: There is paucity of literature regarding health related quality of life in Spasmodic Dysphonia (SD) especially from India. This study assessed HRQoL in it’s global and disease specific aspect by previously validated instruments in patients with SD.Methods: The study was performed in AIIMS, New Delhi. Subjects with SD as well as age and gender matched healthy controls were enrolled from Movement Disorder and botulinum toxin clinic, Department of Neurology, AIIMS, New Delhi. Uneducated patient, those could not read questionnaires & cases who had received botulinum toxin within 6 months were excluded from the study. Each patient filled SF-36, BDI, VoiSS-30 and VPQ questionnaire.Results: 14 pts of Spasmodic Dysphonia (SD) were enrolled. Compared with controls SD patients suffered from statistically significant impaired global health related quality of life (SF36) in areas of role physical (p = 0.007), general health (p = 0.004), social functioning (p = 0.024), role emotion (p = 0.008) and mental health (p=0.039). Patients with SD scored much worse in BDI scale than their control group (12.57±8.0 vs. 4.71±5.0, p=0.005). 65% pt of SD had depression out of whom 14% had moderate depression. SD patient group showed statistically significant impaired scores in disease-specific QOL (VoISS) in 2 out of 3 subscales, impairment (p= <0.001) and emotional (p=<.001) but not in physical (p=0.44). Voice quality of patients with SD was severely affected compared to controls (mean 37± 8.0 vs. 12.9± 1.5).Conclusions: This study clearly demonstrated that patients with SD suffered from significant impairment in HRQoL as compared to controls. Higher proportion of patients with SD suffered from mild to moderate depression compared to their control. 

scholarly journals The Effect of Obesity, Hypertension and Diabetes on Health-related Quality of Life among the Elderly in Saudi Arabia's Eastern Province

2021 ◽  
pp. 540-556
Author(s):  
Othman Al Mulhim ◽  
Salman Abdulrahman Alhumud
Keyword(s):  
Quality Of Life ◽  
Social Functioning ◽  
Bodily Pain ◽  
The Elderly ◽  
Health Related Quality ◽  
Eastern Province ◽  
Related Quality ◽  
Health Related ◽  
Obesity Hypertension

Aims: This study explores the cumulative effects of cardiovascular risk factors on the health-related quality of life (HRQL) among the elderly. Study Design: Our study comprises a cross-sectional design. Place and Duration of Study: The Nov 2021 population-based research represents the Saudi Eastern Province population aged 60 years and above. Methodology: Information was collected through home-based personal interviews using a structured questionnaire on the participants' health. The participants provided informed verbal consent. On each scale of the SF-36 questionnaire, multiple linear regression examined the relationships between obesity, hypertension, diabetes and HRQL after adjusting for sociodemographic data and lifestyle factors. Results: Diabetes and hypertension registered the worst HRQL among males on all the scales (‒53.8 to ‒22.0 points according to the scale) in the two-factor cluster and male clusters except social functioning and role-emotional. Obesity and diabetes registered the worst HRQL on all the scales (–24.4 to –40.4 points according to the scale) in the two-factor female cluster except physical functioning, bodily pain and general health, and on all scales in female clusters except physical functioning, bodily pain, general health, social functioning and role-emotional. Conclusion: Our study shows that obesity, hypertension and diabetes (as separate factors and in combination) negatively affect HRQL.

scholarly journals Health-Related Quality of Life Among Vietnamese Breast Cancer Women

2019 ◽  
Vol 26 (1) ◽  
pp. 107327481986278 ◽  
Author(s):  
Thanh Huong Tran ◽  
Ngoc Linh Trinh ◽  
Yen Hoang ◽  
Thuy Linh Nguyen ◽  
Thu Thao Vu
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Mental Health ◽  
Social Functioning ◽  
Physical Functioning ◽  
Bodily Pain ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

The aim of the study was to investigate health-related quality of life among Vietnamese breast cancer women who were treated at National Cancer Hospital, Hanoi, Vietnam, in 2018. Information about physical functioning, Role Physical, Bodily Pain, General Health, vitality, Social Functioning, Role Emotional, and Mental Health of 200 patients with breast cancer was collected through face-to-face interview, using short form-36 questionnaire. We found that the older patients (older than 50 years) had higher score of Mental Health than patients at age 50 and lower ( P < .05). The patients who had better economic status had significantly higher score of Vitality ( P < .05). Patients who were married and living with their partners/husband had better quality of life in General Health ( P<0.05). The patients who had less than 6 months of treatment had better physical functioning score ( P < .05) than the patients who had treatment longer than 6 months. Patients with caring supports from family members had higher scores of Bodily Pain, Social Functioning, Role Emotional, and Mental Health. Patients who have stressed feelings had significantly lower scores of all domains, except for Physical Functioning. The participants who usually stay up late reported lower scores of all components except for Physical Functioning and Role Physical. In conclusion, it is needed to develop psychosocial services, enhance early screening, and diagnose for the women in Vietnam.

scholarly journals Factors affecting the health-related quality of life of patients with cervical dystonia and impact of treatment with abobotulinumtoxinA (Dysport): results from a randomised, double-blind, placebo-controlled study

BMJ Open ◽  
2014 ◽  
Vol 4 (10) ◽  
pp. e005150 ◽  
Author(s):  
Margaret Mordin ◽  
Catherine Masaquel ◽  
Chandra Abbott ◽  
Catherine Copley-Merriman
Keyword(s):  
Quality Of Life ◽  
Botulinum Toxin ◽  
Bodily Pain ◽  
Botulinum Toxin Type ◽  
Health Related Quality ◽  
Double Blind ◽  
Sf 36 ◽  
Related Quality ◽  
Health Related

ObjectiveTo describe the health-related quality of life (HRQOL) burden of cervical dystonia (CD) and report on the HRQOL and patient perception of treatment benefits of abobotulinumtoxinA (Dysport).DesignThe safety and efficacy of a single injection of abobotulinumtoxinA for CD treatment were evaluated in a previously reported international, multicenter, double-blind, randomised trial. HRQOL measures were assessed in the trial and have not been previously reported.SettingMovement disorder clinics in the USA and Russia.ParticipantsPatients had to have a diagnosis of CD with symptoms for at least 18 months, as well as a total Toronto Western Spasmodic Torticollis Rating Scale (TWSTRS) score of at least 30; a Severity domain score of at least 15; and a Disability domain score of at least 3. Key exclusion criteria included treatment with botulinum toxin type A (BoNT-A) or botulinum toxin type B (BoNT-B) within 16 weeks of enrolment.InterventionsPatients were randomised to receive either 500 U abobotulinumtoxinA (n=55) or placebo (n=61).Primary and secondary outcome measuresEfficacy assessments included TWSTRS total (primary end point) and subscale scores at weeks 0, 4, 8, 12; a pain visual analogue scale at weeks 0 and 4; and HRQOL assessed by the SF-36 Health Survey (SF-36; secondary end point) at weeks 0 and 8.ResultsPatients with CD reported significantly greater impairment for all SF-36 domains relative to US norms. Patients treated with abobotulinumtoxinA reported significantly greater improvements in Physical Functioning, Role Physical, Bodily Pain, General Health and Role Emotional domains than placebo patients (p≤0.03 for all). The TWSTRS was significantly correlated with Physical Functioning, Role Physical and Bodily Pain scores, for those on active treatment.ConclusionsCD has a marked impact on HRQOL. Treatment with a single abobotulinumtoxinA injection results in significant improvement in patients’ HRQOL.Trial registration numberThe trial is registered at ClinicalTrials.gov, numbers NCT00257660 and NCT00288509.

scholarly journals Family Burden and Health Related Quality of Life of HIV Infected Individuals in Madurai, South India

2017 ◽  
Vol 13 (1) ◽  
pp. 1-8 ◽  
Author(s):  
E. Thiruvalluvan
Keyword(s):  
Quality Of Life ◽  
Mental Health ◽  
Social Functioning ◽  
Family Burden ◽  
Health Related Quality ◽  
Interview Schedule ◽  
The Family ◽  
Related Quality ◽  
Health Related

Introduction: With the advent of Highly Active Antiretroviral Therapy (HAART) in 1996, HIV-infected patients are living longer and are concerned not only with treatment’s ability to extend their life butalso with the quality of the life they are able to lead, because, efficacy of treatment is strongly relatedto meaningful outcome i.e., better Quality of Life. Especially Health related quality of life has not been studied well. Hence, this study was necessitated with the objectives to evaluate Health Related Quality of Life (HRQoL) in HIV infected persons on ART. The secondary objectives were to assess the family burden experienced by the families of HIV infected, and measure influence of family burden on overall quality of life.Methodology: The HIV infected individuals who were started on treatment six months prior to date of interview were considered for the study The SF36 (Short Form with 36 questions) was used to evaluate function and mental Health while Pai and Kapur’s Family Burden Interview schedule was used to assess family burden. Interview schedule was pre-tested on 10 HIV infected individuals for consistency. Data analysis was performed using SPSS version 11 (SPSS inc. Chicago, IL, USA). Pearson product moment Correlation were computed to explore the relationships of SF36 with SLI, Family Burden and BMI. Further, Independent student “t” – test was performed to see the association between HRQoL and gender.Results: Of 91 participants interviewed 51.6% were women. Median age (years) of the respondents was 33. The overall mean score for Physical health was 45.13 SD (12.40) and for Mental health 56.91 SD (15.52). Age of HIV infected persons had significant influence in scores in social functioning (p-value .015), emotional well being scores (.015), and Mental health (.010). Socio life Index was directly related to physical health, mental health, Vitality, social functioning and emotional scores on HRQoL. Physicalhealth score was negatively affected by the Family burden score. Similarly, BMI status of the respondents correlated with Mental health, Body Pain, Vitality and Role emotional scores of HRQoL scale SF 36.Conclusion: Socio Life Index and BMI appear to be the two important predictors of HRQoL. Therefore, special attention may be required to HIV infected persons with lower SLI and BMI. Nutritional supplements, in addition to ART drugs, may be provided to ensure some improvements in physical functioning.SAARC J TUBER LUNG DIS HIV/AIDS, 2016; XIII(1), Page: 1-8

scholarly journals Health-related quality-of-life assessment in patients with low back pain using SF-36 questionnaire

Medicina ◽  
2007 ◽  
Vol 43 (8) ◽  
pp. 607 ◽  
Author(s):  
Kotryna Vereščiagina ◽  
Kazys Ambrozaitis ◽  
Bronius Špakauskas
Keyword(s):  
Quality Of Life ◽  
Low Back Pain ◽  
Short Form ◽  
Bodily Pain ◽  
Low Back ◽  
Health Related Quality ◽  
Sf 36 ◽  
Related Quality ◽  
Health Related

Objective. For complete assessment of benefits of the surgical intervention, it is essential to provide evidence of the impact on patients in terms of health status and healthrelated quality of life. In the present study, the preoperative 36-item Short Form (SF-36) Health Survey scores were determined in patients before lumbar microdiscectomy due to better preoperative screening likewise in the control group – almost healthy population taken into account any habitual ailments experienced in an appropriate age. Patients and methods. In the present study, we investigated a cohort of 100 patients with disc herniation causing low back pain and another hundred of the control subjects, matched by age and gender. The short form 36 general health questionnaire (SF-36) was applied. Results. Estimation of the SF-36 scores showed that (1) all of the domain values were considerably lower in the preoperative patient group than in the second one (P<0.01); (2) the bodily pain scores were closely correlated to the social function scores (R=0.7, P<0.01), whereas the physical function was less related to the bodily pain (R=0.6, P<0.01). The weakest correlation was observed between bodily pain and mental health and general health (R=0.4, P<0.01). Conclusion. The present study showed that the generic instrument, SF-36 Health Survey, was optimized paraclinical method for patients predisposed to surgical treatment of the lumbar disc herniation disease likewise for normal population individuals, matched by age and sex, in the assessment of health-related quality of life.

scholarly journals Effects of Diabetic Complications on Health-Related Quality of Life Impairment in Vietnamese Patients with Type 2 Diabetes

2020 ◽  
Vol 2020 ◽  
pp. 1-8 ◽  
Author(s):  
Tuyen Ba Pham ◽  
Trung Thanh Nguyen ◽  
Huyen Thi Truong ◽  
Chin Huu Trinh ◽  
Ha Ngoc Thi Du ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Type 2 Diabetes ◽  
Social Functioning ◽  
Diabetic Complications ◽  
Summary Score ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

Complications of type 2 diabetes mellitus (T2DM) adversely influence patients’ health-related quality of life (HRQOL). This study is aimed at examining HRQOL of T2DM patients, as well as the effects of diabetic complications and comorbidities on HRQOL in this population. This was a hospital-based cross-sectional study on 214 T2DM patients in Hanoi, Vietnam. Short-form 12 version 2 (SF-12v2) and EuroQOL-5 Dimensions-5 Levels (EQ-5D-5L) were employed to measure the HRQOL. The median physical component summary score (PCS), mental component summary score (MCS), and EQ-5D index were 45.6, 56.3, and 0.94, respectively. Having at least one diabetic complication was associated with the reduction of SF-12 scores in social functioning (Diff.=−5.69, 95%CI=−9.24; -2.13), role emotional (Diff.=−1.81, 95%CI=−3.12; -0.51), and MCS (Diff.=−2.55, 95%CI=−5.01; -0.1). Significant decrement of physical functioning, role physical, social functioning, role emotional, and MCS was found in patients having diabetic heart diseases compared to those without diabetic complications. The study revealed that HRQOL of Vietnamese patients with diabetic complications was moderately low, especially in social and mental health perspectives. Strategies to prevent the onset of diabetic complications should be developed as a priority in diabetes management.

scholarly journals Predictors of itch and pain in the 12 months following burn injury: results from the Burns Registry of Australia and New Zealand (BRANZ) Long-Term Outcomes Project

2020 ◽  
Vol 8 ◽  
Author(s):  
Lincoln M Tracy ◽  
Dale W Edgar ◽  
Rebecca Schrale ◽  
Heather Cleland ◽  
Belinda J Gabbe ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Severe Pain ◽  
Burn Injury ◽  
Short Form ◽  
Bodily Pain ◽  
Health Related Quality ◽  
Sf 36 ◽  
Related Quality ◽  
Health Related

Abstract Background Itch and pain are common complaints of patients with burn injuries. This study aimed to describe the prevalence and predictors of itch and moderate to severe pain in the first 12 months following a burn injury, and determine the association between itch, moderate to severe pain, work-related outcomes, and health-related quality of life following a burn injury. Methods Burn patients aged 18 years and older were recruited from five Australian specialist burn units. Patients completed the 36-item Short Form Health Survey Version 2 (SF-36 V2), the Sickness Impact Profile (SIP) work scale, and a specially developed questionnaire relating to itch at 1, 6, and 12 months post-injury. Moderate to severe pain was defined as a score less than 40 on the bodily pain domain of the SF-36 V2. Multivariate mixed-effects regression models were used to identify patient and burn injury predictors of itch and moderate to severe pain. Results Three hundred and twenty-eight patients were included. The prevalence of itch decreased from 50% at 1 month to 27% at 12 months. Similarly, the prevalence of moderate to severe pain decreased from 23% at 1 month to 13% at 12 months. Compared to patients aged 18-34, the adjusted odds of experiencing any itch were 59% (95% CI: 0.20, 0.82) and 55% (95% CI: 0.22, 0.91) lower for patients aged between 35 and 49 and ≥ 50 years, respectively. Compared to patients aged 18-34, the adjusted odds of experiencing moderate to severe pain were 3.12 (95% CI: 1.35, 7.20) and 3.42 (95% CI: 1.47, 7.93) times higher for patients aged 35-49 and ≥ 50 years, respectively. Conclusions Less than 15% of patients reported moderate or severe pain at 12 months, while approximately one-quarter of the patients reported itch at the same period. The presence of moderate to severe pain was associated with a greater negative impact on health-related quality of life and work outcomes compared to itch. Further research is needed to improve our ability to identify patients at higher risk of persistent itch and pain who would benefit from targeted review and intervention studies.

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