scholarly journals Effectiveness of allopurinol on triglyceride levels in hyperuricemic patients

2018 ◽  
Vol 6 (8) ◽  
pp. 2583
Author(s):  
Nermina Žiga ◽  
Fahir Bečić ◽  
Mirza Dedić
Keyword(s):  
Diabetes Mellitus ◽  
Reference Values ◽  
Age Groups ◽  
Type Ii ◽  
Diabetes Mellitus Type Ii ◽  
Statin Group ◽  
Before And After ◽  
Patients With Diabetes ◽  
The Mean ◽  
Clinical Measurements

Background: In this clinical pharmacological research, we dealt with the action of allopurinol on triglyceride levels in hyperuricemic patients.Methods: The study included 40 hyperuricemic patients, of both genders and different age groups, that were sorted by comorbid diagnoses in several subgroups. All patients were clinically treated in the period of three years both at UCC Sarajevo, and P.I. General Hospital "Abdulah Nakaš" Sarajevo. All clinical measurements were carried out using standard IFCC methods with the appropriate analysers.Results: The study was based on mean triglyceride levels before and after three and six months of treatment with allopurinol. It was found out that the mean triglyceride levels were not significantly different from the reference values prior to treatment (p = 0.846) and after three months of therapy (p=0.153). In contrast, after six months of treatment, triglyceride levels significantly increased compared to the reference values. In patients with a diagnosis of gout and metabolic syndrome, triglycerides were statistically significantly increased during the six months of observation. A statin group of patients showed a statistically significant increase in triglyceride levels after three months of therapy (p = 0.032), while, after six months their levels had decreased (p = 0.029). In patients with diabetes mellitus type II, triglycerides rose after three months of treatment (p = 0.039) and retained the same level after six months of observation.Conclusions: The analysis shows that the use of allopurinol has an effect on triglyceride levels in hyperuricemic patients.

scholarly journals PENGARUH MINYAK ZAITUN (OLIVE OIL) TERHADAP KERUSAKAN INTEGRITAS KULIT PADA PASIEN DM TIPE II DI KECAMATAN PAGAR MERBAU

2021 ◽  
Vol 1 (1) ◽  
pp. 125-129
Author(s):  
Kardina Hayati ◽  
Pratiwi Christa Simarmata ◽  
Sari Desi Esta Ulina Sitepu ◽  
Raynald Ignasius Ginting ◽  
Widya Widya
Keyword(s):  
Diabetes Mellitus ◽  
Olive Oil ◽  
Design Research ◽  
Total Sample ◽  
P Value ◽  
Type Ii ◽  
Diabetes Mellitus Type Ii ◽  
Before And After ◽  
Patients With Diabetes ◽  
The One

The success of changing the damage to the integrity of the skin in patients with Diabetes Mellitus Type II depends not only on early detection, but also on understanding the causative mechanism. One condition that can cause damage to the integrity of the skin was the xerosis and pruritus on skin . The purpose of this study to determine the effect of Oil Olive to damage the integrity of the skin in patients with DM type II in the District of Pagar Merbau. This type of research uses the Quasy Experiment Method using the One-Group Pretest-Posttest Design research design. Determination of the sample was done by purposive sampling, with a total sample of 22 people. Data analysis was performed using Paired Sample T Test with 95% confidence interval and α= 0.05. The results of this study indicate the change in damage to the integrity of the skin before and after given a basting oil olives with a p-value = 0.000 (α> 0.05). Conclusion, there was an influence of olive oil on damage to skin integrity in patients with type II DM in Pagar Merbau District which was carried out in accordance with standards. For Health Institutions the need for supervision and counseling to the community that the importance of maintaining skin health especially in patients with diabetes mellitus in Pagar Merbau District        

scholarly journals PENGARUH MINYAK ZAITUN (OLIVE OIL) TERHADAP KERUSAKAN INTEGRITAS KULIT PADA PASIEN DM TIPE II DI KECAMATAN PAGAR MERBAU

2020 ◽  
Vol 3 (1) ◽  
pp. 6-12
Author(s):  
Kardina Hayati ◽  
Hana Setiani Mutiara ◽  
Dewi Agustina ◽  
Tahan Adrianus Manalu ◽  
Kuat Sitepu
Keyword(s):  
Diabetes Mellitus ◽  
Olive Oil ◽  
Design Research ◽  
Total Sample ◽  
P Value ◽  
Type Ii ◽  
Diabetes Mellitus Type Ii ◽  
Skin Integrity ◽  
Before And After ◽  
Patients With Diabetes

ABSTRACT The success of changing the damage to the integrity of the skin in patients with Diabetes Mellitus Type II depends not only on early detection, but also on understanding the causative mechanism. One condition that can cause damage to the integrity of the skin is the xerosis and pruritus on skin . The purpose of this study to determine the effect of Oil Olive to damage the integrity of the skin in patients with DM type II in the District of Pagar Merbau . This type of research uses the Quasy Experiment Method using the One-Group Pretest-Posttest Design research design. Determination of the sample is done by purposive sampling, with a total sample of 22 people. Data analysis was performed using Paired Sample T Test with 95% confidence interval and α = 0.05. The results of this study indicate the change in damage to the integrity of the skin before and after given a basting oil olives with a p-value = 0.000 (α> 0.05). Conclusion, there is an influence of olive oil on damage to skin integrity in patients with type II DM in Pagar Merbau District which is carried out in accordance with standards. For Health Institutions the need for supervision and counseling to the community that the importance of maintaining skin health especially in patients with diabetes mellitus in Pagar Merbau District Keywords : Olive Oil , Skin Integrity Damage , Type II DM patients  

scholarly journals PECULIARITIES OF STATE OF PROTECTION AND AGGRESSION FACTORS IN PATIENTS WITH DIABETES MELLITUS TYPE II AND GASTROESOPHAGEAL REFLUX DISEASE

2020 ◽  
Vol 1 ◽  
pp. 27-34 ◽  
Author(s):  
Aleksey Oparin ◽  
Anton Kudriavtsev ◽  
Anatoliy Oparin
Keyword(s):  
Diabetes Mellitus ◽  
Blood Flow ◽  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Blood Flow Velocity ◽  
Reflux Disease ◽  
Diabetes Mellitus Type ◽  
Type Ii ◽  
Diabetes Mellitus Type Ii ◽  
Patients With Diabetes

Diabetes mellitus is one of the most serious problems of the clinical medicine. This is determined by the fact that it is followed by multisystemic affects, as well as complications on the side of other organs and systems, among which a special place is occupied by gastroesophageal reflux disease. As for the combination and mutual influence of diabetes mellitus and gastroesophageal reflux disease, this issue has not been studied yet, the data of modern literature are not complete and quite contradictory. The aim of the study: to investigate the state of the factors of aggression and protection of the oesophageal mucosa in patients with diabetes mellitus type II with concomitant gastroesophageal reflux disease without associated pathology. Method. There were two groups of patients under observation. The first group included 45 patients with diabetes mellitus type II with concomitant gastroesophageal reflux disease (26 men and 19 women). The second group included 38 patients with gastroesophageal reflux disease without associated pathology – 20 men and 18 women. By sex, age, body weight, Helicobacter pylori infection, smoking and alcohol consumption, both groups were comparable. The surveillance program included determining the compensation ratio of carbohydrate metabolism and the state of the factor. The antioxidant protection factor was assessed by the level of catalase activity in the blood serum, as well as by the diameter of the celiac trunk and the blood flow velocity in it. Statistical processing of the obtained data was carried out with the aid of the program WINDOWS STATISTIKA 6.0. For all types of analysis, differences were considered statistically significant with p<0.05. Results. During the study, we found that in patients with diabetes mellitus type II with concomitant gastroesophageal reflux disease, as well as in patients with gastroesophageal reflux disease without associated pathology, the level of pH-metry was reduced, but with varying measures of confidence. At the same time, we found that patients with GERD without associated pathology had a decrease in the blood flow velocity in the celiac trunk. Concurrently, we ascertained that the decrease in the blood flow velocity in patients of both groups reduced the diameter of the celiac trunk. Conclusions. In patients with diabetes mellitus type II, concomitant gastroesophageal reflux disease has a subtle clinical presentation that is affected by a significant decline in mucosal sealing protection factors. In patients with GERD without associated pathology, typical clinical manifestations, accompanied by inflammation, acid regurgitation and dyspepsia, are more vivid.

PREVALENCE OF DIABETIC NEUROPATHY IN PATIENTS WITH DIABETES MELLITUS TYPE II

2011 ◽  
Vol 22 ◽  
pp. S29
Author(s):  
Triada Exiara ◽  
Apostolos Konstantis ◽  
Maria Kouroupi ◽  
Anastasia Georgoulidou ◽  
Dimitra Papadopoulou ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Diabetic Neuropathy ◽  
Diabetes Mellitus Type ◽  
Type Ii ◽  
Diabetes Mellitus Type Ii ◽  
Patients With Diabetes

scholarly journals Protein spectrum of blood plasma in patients with diabetes mellitus type II

2018 ◽  
Vol 3 (2) ◽  
pp. 95-105
Author(s):  
V. Ionova ◽  
V. Lantsova ◽  
E. Tkach ◽  
R. Ziganshin ◽  
V. Shender ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Blood Plasma ◽  
Diabetes Mellitus Type ◽  
Type Ii ◽  
Diabetes Mellitus Type Ii ◽  
Protein Spectrum ◽  
Patients With Diabetes
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