scholarly journals Extranodal rosai dorfman disease: a case report of single soft tissue cystic lesion

Author(s):  
Ruchi Agrawal ◽  
Anurag Saha ◽  
Bhanita Baro

Rosai-Dorfman disease (RDD) is an uncommon benign histiocytic disorder. It is found worldwide and slightly more common among in men (1.4:1), affecting individuals are with an average age of 20.6 years. Extranodal tissue involvement is documented in 25-43% of RDD patients. Here authors are discussing a case of 16-year-old male patient with the complaint of a single swelling over left forearm since one month with no lymphadenopathy. Radiology showed anechoic collection within the muscle and superficial to it. On microscopy, smear showed diffusely distributed histiocytes with cytoplasm showing intact lymphocytes with halo surrounding it (emperipolesis), without atypia. Based on cytomorphology diagnosis of Extranodal Rosai Dorfman Disease was made.

2018 ◽  
Vol 17 (4) ◽  
pp. 452 ◽  
Author(s):  
Rubyath C. Rajib ◽  
Rajasekharan Pillai ◽  
Ibrahim A. Sulaiman ◽  
Ibrahim Al-Haddabi

Rosai-Dorfman disease (RDD) is a rare benign proliferative histiocytic disorder characterised by massive lymphadenopathy. While extranodal involvement can occur in generalised RDD, isolated soft tissue RDD (STRDD) is extremely rare. We report a 17-year-old male patient who presented to the maxillofacial outpatient department of the Sultan Qaboos Hospital, Salalah, Oman, in 2015 with a painless cheek mass which had been slowly growing over the previous two months. Routine histopathological examinations and immunohistochemistry confirmed a diagnosis of STRDD. Currently, surgical excision is considered to be the most effective curative treatment for STRDD, as the outcomes of other treatment modalities are still unknown. Despite its rarity, STRDD should be considered in the differential diagnosis of histiocytic soft tissue lesions.


2019 ◽  
Vol 6 (9) ◽  
pp. 3359
Author(s):  
Joachim Wen Kien Yau ◽  
Cher Heng Tan ◽  
Cora Yuk Ping Chau ◽  
Kar Yong Wong

Primary retroperitoneal mucinous cystic neoplasms are very rare, especially in men. To our knowledge, only 13 cases of such neoplasms have been reported in men to date. The most common type is the primary retroperitoneal mucinous cystadenoma, which almost invariably affects females. Most patients present with non-specific symptoms. In this case report, we will describe a case of a 53 year old male patient who presented with raised CEA tumour marker and vague right sided abdominal discomfort. A computed tomography (CT) scan was performed, which revealed a 4.9 × 4.7 × 7.5 cm lobulated retroperitoneal cystic lesion abutting the posterior wall of the mid ascending colon. A laparoscopic excision was eventually performed with complete removal of the retroperitoneal cystic lesion. Subsequent histological assessment confirmed the diagnosis of a primary retroperitoneal mucinous cystadenoma with borderline malignancy. On comparison with a prior CT scan performed about seven and a half years earlier, we managed to derive a doubling rate of about 626 days, which is the first reported case in English literature to document the growth rate of such a tumour. The patient has since been discharged well, with no evidence of tumour recurrence on an interval CT scan.


2018 ◽  
Vol 10 (4) ◽  
pp. 7
Author(s):  
Puji Supriyono ◽  
Gando Sari ◽  
Nursama Heru Apriantoro ◽  
Win Priantoro ◽  
Samsun Samsun ◽  
...  

Gynecomastia is hypertrophy abnormality of male’s breast gland soft tissue. In that case, the mammography is difficult to show the malignant masses. The ultrasonography is often useful and really important examination to confirm the diagnosis by showing retroareolar hypoechoic mass and or elevation of hyperechoic on parenchyma gland. Gynecomastia is very rare cases in older man. This case report shows 67 years old patient on compos mentis state, who has left breast enlargement.


Author(s):  
S. Sathish Kumar ◽  
N. T. Sreedevi ◽  
Aarudhra Premchander

<div class="WordSection1"><p class="abstract">Rhinosporidiosis is a granulomatous disease caused by <em>Rhinosporidium seeberi</em>, usually affecting the nasal mucosa. Involvement of other sites of body in rhinosporidiosis especially, the lacrimal sac involvement is very rare. Hence, we report a case of lacrimal sac rhinosporidiosis in an adult male patient who presented with infraorbital swelling.</p></div>


2014 ◽  
Vol 142 (suppl_1) ◽  
pp. A288-A288
Author(s):  
Siddharth Bhattacharyya ◽  
Ashish Bains ◽  
Jasvir Khurana ◽  
Paul Zhang ◽  
Xinmin Zhang

2020 ◽  
Author(s):  
Abdulrahman Fahad Al Kandari ◽  
Abdulwahab Fahad Alkandari ◽  
Sarah Faisal Alhendi ◽  
Hussain Saleh Almousawi ◽  
Hisham Adel Burezq

Abstract Objective: This report describes a case of a monophasic synovial sarcoma that was initially misdiagnosed as an infantile hemangioma in a 3-month-old female infant. We also discuss the basic elements of evaluating a soft-tissue mass and important radiological and clinical features that should raise the index of suspicion for a synovial sarcoma. Summary Background Data: Synovial sarcoma is a rare pathology that is often challenging to diagnose due to its similarities with more common vascular lesions that occur in infancy. Infantile hemangioma, in particular, is common, has distinctive clinical and radiological findings, and is frequently diagnosed without histological confirmation. This increases the risk of misdiagnosis of rare tumors in infancy. Case Report: A 3-month-old female infant presented with a soft-tissue mass on the left forearm. Physical examination showed a well-defined, subcutaneous mass on the left forearm, measuring approximately 3 cm × 5 cm, firm in consistency, with no cutaneous involvement and normal skin coverage. Imaging suggested an infantile hemangioma but, due to the atypical presentation, a trial of beta-blocker therapy was conducted to confirm the diagnosis. The patient showed no clinical response to beta-blocker therapy, and therefore an incisional biopsy was performed. Using histopathology, the tumor was diagnosed as a monophasic synovial sarcoma.Conclusions: We highlight a rare presentation of a synovial sarcoma in a neonate and caution against making a diagnosis without histopathologic analysis. Clinicians should include sarcoma in the differential diagnosis when assessing a mass in neonates, as early diagnosis and intervention can reduce morbidity and mortality.MINI ABSTRACT A 3-month-old infant presented with a left forearm soft-tissue mass, initially diagnosed as infantile hemangioma. Biopsy revealed a monophasic synovial sarcoma. We discuss the basic elements of evaluating a soft-tissue mass and important radiological and clinical features that should raise the index of suspicion for a synovial sarcoma.


Author(s):  
Yazid Bin Pol Ong ◽  
Loong Siow Ping ◽  
Khor Foo Kiang ◽  
Gan Soon Ching ◽  
Angeline Bt Madatang ◽  
...  

<p class="abstract">Rosai Dorfman disease (RDD) is a rare granulomatous disease that typically presents with massive lymphadenopathy. To our knowledge, there have only been 650 cases reported worldwide. It is more common among adults and has characteristic clinical, radiological and histopathological findings. Here, we present a case of RDD in a 51 year-old man with massive submental lymphadenopathy which was not responding to antibiotics. Computerized Tomographic Scan showed ill-defined non-enhancing soft tissue density while fine needle aspiration for cytology displayed emperipolesis which is seen in patients with RDD. The swelling followed a benign course and reduced in size progressively without further intervention.</p><p class="abstract"> </p>


2007 ◽  
Vol 86 (10) ◽  
pp. 624-627 ◽  
Author(s):  
Lisa Lee ◽  
Christine M. Glastonbury ◽  
Doris Lin

Rosai-Dorfman disease is a rare, benign granulomatous disease that typically presents with massive cervical lymphadenopathy. In less than 50% of cases, other soft-tissue manifestations may also be found in the head and neck. Rosai-Dorfman disease can be difficult to diagnose because of its rarity and its ability to mimic, both clinically and radiologically, more common diseases such as lymphoma. The histopathologic diagnosis can also be difficult to make, particularly when the disease exhibits extranodal manifestations. We present a case of isolated extranodal Rosai-Dorfman disease involving the carotid sheath, without the typical massive adenopathy.


Sign in / Sign up

Export Citation Format

Share Document