scholarly journals Role of Topical Corticosteroid Therapy in Various Dermatoses

2021 ◽  
Author(s):  
Jitendra Kishore Singh ◽  
Yogesh Rupram Zanwar ◽  
Jagannath Kumar ◽  
Jatin Jayeshbhai Patel ◽  
Vineet Chandrabhushan Dube ◽  
...  
Keyword(s):  
Skin Diseases ◽  
Case Series ◽  
Immunosuppressive Agent ◽  
Systemic Absorption ◽  
Cream Formulation ◽  
High Penetration ◽  
United States Food ◽  
Chronic Skin ◽  
Us Fda ◽  
Chronic Skin Diseases

Topical corticosteroids are the cornerstone in managing several dermatologic disorders, including plaque psoriasis.Managing plaque psoriasis warrants the use of an effective anti-inflammatory, antimitotic, antipruritic, and immunosuppressive agent, such as clobetasol propionate (CP). Recently, CP 0.025% cream received approval by United States food and drug administration (US FDA) for the treatment of moderate-to-severe psoriasis in adult patients. CP 0.025% cream has proven efficacious in chronic skin diseases, including controlling inflammation and pruritus, in various steroid-responsive dermatoses. In contrast to prior CP formulations, this novel CP 0.025% cream formulation does not contain propylene glycol, short-chain alcohols, and sorbitol-based emulsifiers, which are known contact allergens. The other beneficial attributes of this CP 0.025% cream formulation are high penetration of active ingredients and a lower degree of systemic absorption. This case series discusses the experience of using CP 0.025% cream in terms of its efficacy and safety in various dermatologic conditions. 

scholarly journals Treatment with clobetasol propionate 0.025% topical therapy in various dermatoses

2021 ◽  
Vol 10 (1) ◽  
pp. 250
Author(s):  
Ashwini Guttedar ◽  
Nitin Mishra ◽  
Sanjay Kumar Gupta ◽  
Atul Dilip Mohankar ◽  
Karan Sancheti ◽  
...  
Keyword(s):  
Topical Therapy ◽  
Case Series ◽  
The United States ◽  
Hand Eczema ◽  
Clobetasol Propionate ◽  
Systemic Absorption ◽  
Chronic Hand Eczema ◽  
High Penetration ◽  
United States Food ◽  
Anti Inflammatory

Owing to their anti-inflammatory and vasoconstrictive properties. Topical corticosteroids (TCs) provide benefits in various dermatological conditions, including atopic eczema, psoriasis, chronic hand eczema, and localized vitiligo. Clobetasol propionate (CP) is the most common topical agent possessing anti-inflammatory, antimitotic, antipruritic, and immunosuppressive properties that are employed in the management of plaque psoriasis. CP 0.025% cream was approved by the United States food and drug administration for the treatment of moderate-to-severe psoriasis in adult patients. The formulation is free from known contact allergens, such as propylene glycol, short-chain alcohols, and sorbitol-based emulsifiers, and has demonstrated hypoallergenic effects. High penetration of active ingredients and a lower degree of systemic absorption make CP 0.025% an effective and safe agent. This case series discusses the clinical experience of using CP 0.025% cream in various dermatologic conditions, focusing on its efficacy and safety.

The Constructive Thinking Inventory: Factorial Structure in Healthy Individuals and Patients with Chronic Skin Diseases

1998 ◽  
Vol 14 (3) ◽  
pp. 226-233 ◽  
Author(s):  
Jürgen Hoyer ◽  
Mechthild Averbeck ◽  
Thomas Heidenreich ◽  
Ulrich Stangier ◽  
Karin Pöhlmann ◽  
...  
Keyword(s):  
Skin Diseases ◽  
Principal Component ◽  
Initial Study ◽  
Statistical Independence ◽  
Constructive Thinking ◽  
Global Factor ◽  
Emotional Coping ◽  
Factor Congruence ◽  
Chronic Skin ◽  
Chronic Skin Diseases

Epstein's “Constructive Thinking Inventory” (CTI) was developed to measure the construct of experiential intelligence, which is based on his cognitive-experiential self-theory. Inventory items were generated by sampling naturally occurring automatic cognitions. Using principal component analysis, the findings showed a global factor of coping ability as well as six main factors: Emotional Coping, Behavioral Coping, Categorical Thinking, Personal Superstitious Thinking, Esoteric Thinking, and Naive Optimism. We tested the replicability of this factor structure and the amount of statistical independence (nonredundancy) between these factors in an initial study of German students (Study 1, N = 439) and in a second study of patients with chronic skin disorders (Study 2, N = 187). Factor congruence with the original (American) data was determined using a formula proposed by Schneewind and Cattell (1970) . Our findings show satisfactory factor congruence and statistical independence for Emotional Coping and Esoteric Thinking in both studies, while full replicability or independence could not be found in both for the other factors. Implications for the use and further development of the CTI are discussed.

167 Influence of Chronic Skin Diseases on Male Sexual Function in Upper Egypt

2017 ◽  
Vol 14 (2) ◽  
pp. e69
Author(s):  
H. Abdel Hafez ◽  
A.A. Abdel-Motaleb ◽  
H.D. Gaber ◽  
G.S.T. Al-Attar
Keyword(s):  
Sexual Function ◽  
Skin Diseases ◽  
Upper Egypt ◽  
Male Sexual Function ◽  
Chronic Skin ◽  
Chronic Skin Diseases

scholarly journals Influência de fatores emocionais nas doenças crônicas de pele: O estresse como gatilho para o desenvolvimento, reincidência ou agravamento da psoríase / Influence of emotional factors on chronic skin diseases: Stress as a trigger for development, recurrence or worsening of psoriasis

2019 ◽  
Vol 13 (46) ◽  
pp. 584-608
Author(s):  
Manuela Sobral Bentes de Melo ◽  
Nara Freire Leão Rocha ◽  
Stéfany Silva Magalhães ◽  
Lais Landim Sousa
Keyword(s):  
Skin Diseases ◽  
Emotional Factors ◽  
Chronic Skin ◽  
Chronic Skin Diseases

Diversos estudos têm revelado a existência de uma relação entre aspectos psicossociais e o desenvolvimento ou agravamento de dermatoses crônicas, dentre as quais se encontra a psoríase. Fatores psicológicos, stress e outros eventos da vida são capazes de agravar de 40 e 80% dos casos. O estudo objetivou analisar a forma como esses aspectos podem ensejar o surgimento, a reincidência ou a acentuação do quadro clínico. Metodologia: Estudo de casos concretos com pacientes portadores da psoríase, além de uma vasta literatura bibliográfica acerca da temática. Conclusão: Ficou demonstrada a importância do tratamento psíquico e fisiológico, bem como a necessidade do desenvolvimento de estratégias de coping para enfretamento das situações sociais envolvidas.   

Comparison of Personality Traits among Patients with Psoriasis, Atopic Dermatitis, and Stress: A Pilot Study

Dermatology ◽  
2020 ◽  
Vol 236 (4) ◽  
pp. 324-328 ◽  
Author(s):  
Lynda Grine ◽  
Giulia Tochtermann ◽  
Hilde Lapeere ◽  
Nele Maes ◽  
Günther F.L. Hofbauer ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Pilot Study ◽  
Personality Traits ◽  
Skin Diseases ◽  
Work Related Stress ◽  
Work Related ◽  
Chronic Skin ◽  
Related Stress ◽  
Chronic Skin Diseases ◽  
The Impact

Background: Psoriasis and atopic dermatitis are chronic skin diseases that greatly affect the quality of life. Both diseases can be triggered or exacerbated by stress. Objective: We aimed to differentiate personality traits between patients with chronic skin conditions and people treated for stress in a pilot study. Methods: Patients participating voluntarily in educational programs in Belgium and Switzerland were recruited to complete personality trait questionnaires, including the Temperament and Character Inventory (TCI) and the Tridimensional Personality Questionnaire (TPQ). A comparison was made with patients treated for work-related stress. Results: A total of 48 and 91 patients suffering from skin diseases and work-related stress, respectively, were included in the study. Based on the questionnaires, we found that dermatology patients were less persistent and impulsive than those with work-related stress. Dermatology patients also exhibited more rigidness and less focus on performance. Finally, patients with work-related stress seem more likely to change in response to health-promoting programs than patients with chronic dermatoses. Conclusion: Patients with chronic skin diseases may perceive and cope with stress differently in comparison to patients with work-related stress due to inherent personality traits. Therefore, stress coping mechanisms may differ among different diseases. More research is needed into the design of educational interventions and the impact of personality traits in disease-specific groups.

Biopolymeric films as delivery vehicles for controlled release of hydrocortisone: Promising devices to treat chronic skin diseases

2020 ◽  
Vol 114 ◽  
pp. 111074
Author(s):  
Guilherme T. Voss ◽  
Matheus S. Gularte ◽  
Renata L. de Oliveira ◽  
Cristiane Luchese ◽  
André R. Fajardo ◽  
...  
Keyword(s):  
Controlled Release ◽  
Skin Diseases ◽  
Delivery Vehicles ◽  
Chronic Skin ◽  
Chronic Skin Diseases

scholarly journals The Price for Treatment of Chronic Skin Diseases: Different Approaches

Dermatology ◽  
2006 ◽  
Vol 214 (1) ◽  
pp. 6-7 ◽  
Author(s):  
Joachim W. Fluhr ◽  
Michael Jünger
Keyword(s):  
Skin Diseases ◽  
Chronic Skin ◽  
Chronic Skin Diseases
Sign in / Sign up

Export Citation Format

Share Document