scholarly journals Granulomatous mastitis-a challenging surgical entity

2017 ◽  
Vol 4 (6) ◽  
pp. 2077 ◽  
Author(s):  
Thrishuli P. B. ◽  
Akshata Kamath B.
Keyword(s):  
Breast Disease ◽  
Needle Aspiration ◽  
Chronic Inflammatory Disease ◽  
Wide Excision ◽  
Reproductive Age ◽  
Excision Biopsy ◽  
Granulomatous Mastitis ◽  
Idiopathic Granulomatous Mastitis ◽  
Short Course ◽  
Needle Aspiration Cytology

Background: Idiopathic granulomatous mastitis is a rare benign breast disease, first described by Kessler and Wolloch in 1972. It is characterized by chronic necrotizing granulomatous lobulitis of unknown aetiology. The objective of the study is to find out the clinical and management profile of granulomatous mastitis (GM). This study was carried out at JSS hospital, Mysore, Karnataka, India during the period 2014-2016.Methods: Histopathologically diagnosed cases of GM were studied. Data included, detailed history, examination, clinical diagnosis, ultrasound, mammogram and fine needle aspiration cytology (FNAC). All patients were followed for a period of 6 months. Recurrent cases were managed by wide excision and followed for another period of 6 months.Results: 8 patients who were hisptopathologically diagnosed to have granulomatous mastitis were studied. The mean age was found to be 43.5 years. All patients presented with a painless breast lump and were unilateral. The incidence of the same was found to be higher (3.7%) compared to other large volume studies. The best treatment modality with least recurrence in 4 cases was wide local excision and 1 case of quandrantectomy.Conclusions: GM is an uncommon chronic inflammatory disease of the breast. Usually involving a single non-lactating breast in reproductive age group. It clinically mimics tuberculosis and carcinoma. Mammography remains non-conclusive. Excision and wide excision biopsy are both diagnostic and therapeutic in majority of cases. Treatment includes short course of steroids and antibiotic along with close regular surveillance.

Idiopathic Granulomatous Mastitis: Cytologic and Histologic Study of 65 Egyptian Patients

2016 ◽  
Vol 60 (5) ◽  
pp. 438-444 ◽  
Author(s):  
Thanaa El A. Helal ◽  
Lobna S. Shash ◽  
Somaia A. Saad El-Din ◽  
Sally M. Saber
Keyword(s):  
Middle Eastern ◽  
Breast Disease ◽  
Needle Aspiration ◽  
Granulomatous Mastitis ◽  
Aspiration Cytology ◽  
Idiopathic Granulomatous Mastitis ◽  
Tissue Sections ◽  
Egyptian Patients ◽  
Needle Aspiration Cytology

Background: The etiology of idiopathic granulomatous mastitis (IGM) is unknown, and it is commonly misdiagnosed clinically and/or radiologically as breast cancer. The role of fine-needle aspiration cytology (FNAC) in its diagnosis is still a matter of debate. The aim of the current study is to assess the value of FNAC in the diagnosis of IGM, and to search for the presence of bacteria in IGM with cystic vacuoles, which was described recently by a few authors. Materials and Methods: Retrospective study of cytologic smears and histologic tissue sections of 65 Egyptian IGM cases was done along with microbiologic testing. A comparison of the frequency of IGM in Egypt to that of other populations was also made. Results: IGM has typical FNA features which can easily exclude malignancy. Histologically, cystic vacuoles were encountered in 35 out of 65 cases (53.9%), with only 6 (17.14%) of these cases showing Gram-positive bacilli (GPB). The frequency of IGM in Egypt is comparable to those in other Middle Eastern countries but much higher than in Western countries. Conclusion: IGM is a common breast disease in Egypt. FNAC in IGM has a high diagnostic accuracy. This study supports the few recent studies that have detected GPB in IGM with cystic vacuoles. Thus, bacteriologic examination in such cases may affect the treatment strategy.

scholarly journals Idiopathic granulomatous mastitis with erythema nodosum and polyarthritis

Reumatismo ◽  
2016 ◽  
Vol 68 (2) ◽  
pp. 97 ◽  
Author(s):  
J. Alungal ◽  
M.C. Abdulla ◽  
R. Narayan
Keyword(s):  
Erythema Nodosum ◽  
Oral Prednisolone ◽  
Needle Aspiration ◽  
Left Breast ◽  
Chronic Inflammatory Disease ◽  
Granulomatous Mastitis ◽  
Aspiration Cytology ◽  
Idiopathic Granulomatous Mastitis ◽  
Painful Mass ◽  
Needle Aspiration Cytology

A 25 year-old woman presented with a painful mass in the left breast, polyarthritis and erythema nodosum. Fine needle aspiration cytology led to a diagnosis of granulomatous mastitis. Oral prednisolone rapidly improved the arthritis and the erythema nodosum. Granulomatous mastitis is a very rare, chronic inflammatory disease and only ten patients with granulomatous mastitis with erythema nodosum and polyarthitis have been described.

scholarly journals Cytological spectrum of granulomatous mastitis: diagnostic and treatment challenges

2018 ◽  
Vol 6 (11) ◽  
pp. 3616
Author(s):  
Shalini Bhalla ◽  
Preeti Agarwal ◽  
Harshita Agarwal ◽  
Sameer Gupta ◽  
Prateek Mehrotra ◽  
...  
Keyword(s):  
Needle Aspiration ◽  
Granulomatous Mastitis ◽  
Idiopathic Granulomatous Mastitis ◽  
Inflammatory Lesions ◽  
Malignant Lesions ◽  
Needle Aspiration Cytology ◽  
High Degree ◽  
Work Up ◽  
Detailed Work

Background: Granulomatous mastitis (GM) is an inflammatory disease of the breast which clinico- radiologically mimics both inflammatory and malignant lesions. This leads to diagnostic dilemmas and delay in treatment. The aim of the present study was to review the cases diagnosed as granulomatous mastitis on Fine Needle Aspiration Cytology (FNAC) with an objective to co-relate their clinico-radiological findings, histology review where available and follow up treatment received to establish etiology and study the treatment outcome.Methods: Cytologically diagnosed cases of granulomatous mastitis were retrieved and reviewed from August 2015 - July 2017 records. Clinico-radiological co-relation, histology review where available and follow up treatment records were sought for.Results: Around 31.7% (530/1670) cases were reported as malignant, 60.3% (1009/1670) as benign proliferative and 7.9% (131/1670) as inflammatory lesions by breast FNA. 3.1% (51/1670) cases were reported as GM of all breast FNAC and 38% (51/131) of all inflammatory lesions. Follow up was available for 47 cases. Of which 26 (55.3%) cases were diagnosed as Tubercular Granulomatous mastitis (TGM) and 21(44.7%) were idiopathic granulomatous mastitis (IGM).Conclusions: Countries where tuberculosis is endemic, high degree of clinical suspicion and detailed work-up to rule out TGM is essential for all cases of granulomatous mastitis. Authors recommend a multidisciplinary workup with microbiological culture and molecular based tests on FNA material. This retrospective study illustrates that the cause of GM needs to be determined accurately for timely treatment, to avoid unnecessary delays and treatment dilemma in these patients.

scholarly journals The utility of fine-needle aspiration cytology in differentiating granulomatous mastitis and tuberculous mastitis

2021 ◽  
Vol 7 (1) ◽  
pp. 26-32
Author(s):  
Dr. Challa Sukumar ◽  
◽  
Dr. Garima Singh ◽  
Dr. Shakti Kumar Yadav ◽  
Dr. Aarzoo Jahan ◽  
...  
Keyword(s):  
Accurate Method ◽  
Needle Aspiration ◽  
Epithelioid Cell ◽  
Chronic Inflammatory Disease ◽  
Granulomatous Mastitis ◽  
Diagnostic Dilemma ◽  
Treatment Protocols ◽  
Appropriate Treatment ◽  
Equal Side ◽  
Needle Aspiration Cytology

Background: Tuberculous mastitis (TM) is a rare extrapulmonary presentation of tuberculosisaccounting for less than 1% of all diseases of the breast in the industrialized world. GranulomatousMastitis (GM) is an uncommon chronic inflammatory disease of the breast that almost always mimicscancer in young individuals, so it can be a diagnostic dilemma. Aims and objectives: The main aimof this study is to elucidate the utility of FNAC in differentiating granulomatous mastitis andtuberculous mastitis. Materials & Methods: A retrospective observational study was conducted atthe department of pathology, Hindu Rao Hospital, Delhi. Cytology database was revealed for a periodof 4 years (2016-2019). The clinical details wherever available and cytological morphology ofindividual cases were noted and analysed. Results: In our study out of 20 cases 11 cases (55%)were found to be granulomatous mastitis and the other 9 cases (45%) were found to be tuberculousmastitis. All cases were of female patients only, with equal side distribution. In the cytologicalsmears of GM, three (27.3%) smears showed ductal epithelial cells, epithelioid cell granulomas wereseen in 11 (100%) cases and singly scattered epithelioid cells were seen in nine (81.8%) cases.Caseous necrosis was observed only in one case (9.09%) but necrotic material intermixed withdegenerated neutrophils and apoptotic bodies were seen in four cases (36.4%). Conclusion: FNACcan be an accurate method for differentiating tuberculous mastitis from granulomatous mastitis asper cytomorphological findings, along with confirmation by the demonstration of acid-fast bacilli andhence can help to decide the appropriate treatment protocols for such patients.

scholarly journals Idiopathic granulomatous mastitis: challenges of treatment in iranian women

BMC Surgery ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Leyla Shojaee ◽  
Nasrin Rahmani ◽  
Siavash Moradi ◽  
Asieh Motamedi ◽  
Gholamali Godazandeh
Keyword(s):  
Recurrence Rate ◽  
Low Dose ◽  
Unknown Origin ◽  
Surgical Excision ◽  
Chronic Inflammatory Disease ◽  
High Dose ◽  
Granulomatous Mastitis ◽  
Idiopathic Granulomatous Mastitis ◽  
Results Of Treatment ◽  
Information Treatment

Abstract Background and objective As a chronic inflammatory disease of an unknown origin, the treatment of granulomatous mastitis has always been controversial. According to some researchers, surgical treatment and certain medications, especially steroids, are more effective in treating the disease. This study aimed at evaluating the results of treatment in a group of patients with granulomatous mastitis. Materials and methods This longitudinal cohort study evaluated the treatment outcomes of 87 patients with pathology-confirmed granulomatous mastitis referred to the surgical clinic of Central Hospital in Sari, Iran. Demographic, clinical, and pathological information, treatment methods and results, and the recurrence rate were analyzed. Findings A total of 87 female patients with granulomatous mastitis aged 22–52 years with a mean age of 34 years were evaluated. All patients had palpable masses; the breast masses were painful in 48.3% of patients, and 55.2% of patients suffered from erythema and inflammation, and8% had fistulas and ulcers at the inflammation site. The patients were followed-up for an average duration of 26 months (8–48 months) after treatment and recovery. The overall recurrence rate was 24.1%, and the recurrence rate was 29.4% in patients underwent surgery, 34.8% in patients received high-dose prednisolone, and 17% in those received low-dose prednisolone together with drainage (p < 0.001). Conclusions According to the results, the low-dose prednisolone plus drainage was more effective with a lower recurrence rate than only surgical excision or high-dose prednisolone. In fact, the use of minimally invasive methods such as drainage plus low-dose steroids is a more effective method with fewer side effects than the other two methods.

scholarly journals Case of Lingual Cysticercosis and Review of Literature

2012 ◽  
Vol 4 (01) ◽  
pp. 056-058 ◽  
Author(s):  
Arvind Kinger ◽  
Mallika Kawatra ◽  
Tej Singh Chaudhary
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Needle Aspiration ◽  
Excision Biopsy ◽  
Review Of Literature ◽  
Aspiration Cytology ◽  
Lateral Border ◽  
Fine Needle ◽  
Tongue Muscles ◽  
Needle Aspiration Cytology

ABSTRACTA 30-year-old female presented with a painless solitary swelling at right lateral border of tongue of 2-month duration. Fine-needle aspiration cytology was nonconclusive. Excision biopsy was done. Histopathology revealed cysticercosis cellulosae and parasite visualized in the slide with tongue muscles. Lingual cysticercosis is rare and therefore its literature is reviewed and discussed.

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