scholarly journals Retrospective and prospective analysis of clinical, radiological and prognostic factors affecting surgical denouement in ossified posterior longitudinal ligament: an institutional experience

2019 ◽  
Vol 6 (3) ◽  
pp. 847
Author(s):  
Rajesh R. Raykar ◽  
Guruprasad Bettaswamy ◽  
Rajesh Kumar Singh ◽  
Mahendra M.

Background: The most common cause of radiculopathy or myelopathy is “ossification of the posterior longitudinal ligament (OPLL)”. Surgical management consists of various anterior and posterior procedures. Anterior procedures done are corpectomy and fusion. Posterior procedures include laminectomy and laminectomy with fusion that include the use of lateral mass or pedicle screws with rods. Objective was to study the clinical course and to delineate clinico-radiological prognostic factors with regard to surgical outcome.Methods: Patients operated for cervical OPLL were included. Detailed clinical history and radiological findings were retrospectively taken from the case records of the patients and prospectively recorded in the cases operated till May 2018. A minimum follow-up of 6 months was done for improvement. Preoperative clinical evaluation was done. Surgical options were individualized for each patient. Detailed clinical evaluation was done at discharge and at follow-up.Results: It has been found that those patients who were admitted with Nurick’s myelopathy grade IV and V at admission, those with higher number of levels involved like 5, 6 and 7, those with duration of symptoms of more than one year were more likely to have same or deteriorated outcome compared to their counterparts. Other parameters were not found to be significantly associated with outcome.Conclusions: Duration of symptoms >12 months, Sphincter disturbances were significant poor clinical prognostic markers. Significant poor radiological prognostic markers were segmental stenotic index <0.4, MRI T2-Weighted hyper intense signal change.

2015 ◽  
Vol 9 (11-12) ◽  
pp. 800 ◽  
Author(s):  
Mohamed Tarchouli ◽  
Ahmed Bounaim ◽  
Mohamed Essarghini ◽  
Moulay Brahim Ratbi ◽  
Mohamed Said Belhamidi ◽  
...  

Introduction: Fournier’s gangrene is a rapidly progressing necrotizing fasciitis of the perineum and genital area associated with a high mortality rate. We presented our experience in managing this entity and identified prognostic factors affecting mortality.Methods: We carried out a retrospective study of 72 patients treated for Fournier’s gangrene at our institution between January 2005 and December 2014. Patients were divided into survivors and nonsurvivors and potential prognostic factors were analyzed.Results: Of the 72 patients, 64 were males (89%) and 8 females (11%), with a mean age of 51 years. The most common predisposing factor was diabetes mellitus (38%). The mortality rate was 17% (12 patients died). Statistically significant differences were not found in age, gender, and predisposing factors, except in heart disease (p = 0.038). Individual laboratory parameters significantly correlating with mortality included hemoglobin (p = 0.023), hematocrit (p = 0.019), serum urea (p = 0.009), creatinine (p = 0.042), and potassium (p = 0.026). Severe sepsis on admission and the extent of affected surface area also predicted higher mortality. Others factors, such as duration of symptoms before admission, number of surgical debridement, diverting colostomy and length of hospital stay, did not show significant differences. The median Fournier’s Gangrene Severity Index (FGSI) was significantly higher in non-survivors (p = 0.002).Conclusion: Fournier’s gangrene is a severe surgical emergency requiring early diagnosis and aggressive therapy. Identification of prognostic factors is essential to establish an optimal treatment and to improve outcome. The FGSI is a simple and valid method for predicting disease severity and patient survival.


2007 ◽  
Vol 7 (1) ◽  
pp. 13-20 ◽  
Author(s):  
Toshimi Aizawa ◽  
Tetsuro Sato ◽  
Hirotoshi Sasaki ◽  
Fujio Matsumoto ◽  
Naoki Morozumi ◽  
...  

Object Thoracic myelopathy is uncommon compared with cervical myelopathy. In this study, data obtained in patients with thoracic myelopathy caused by degenerative processes of the spine were retrospectively analyzed to clarify the surgical outcomes and to examine the various factors affecting the postoperative improvement. Methods Between 1988 and 2002, 132 patients with thoracic myelopathy underwent surgery and a minimum 2-year observation period. Clinical data were collected from medical and operative records, and sagittal alignment of the spine was measured on radiographs. The patients were evaluated pre- and postoperatively using the modified Japanese Orthopaedic Association (JOA) scale (maximum score 11). The relationships among various factors affecting the preoperative severity of myelopathy and postoperative improvement were also examined. Results The population consisted of 97 men (mean age at surgery was 58 years) and 35 women (mean age at surgery 62 years). Myelopathy was caused by ossification of the ligamentum flavum (OLF) in 73 patients, ossification of the posterior longitudinal ligament (OPLL) in 21, combined OLF–OPLL in 10, intervertebral disc herniation (IDH) in 15, posterior bone spur in 11, and OLF with IDH or posterior bone spur in one patient each. The surgical outcome was relatively good: a mean preoperative JOA score of 5.3 improved to a mean score of 7.8 at the last follow-up, 50 months on average after surgery. Thoracic myelopathy caused by OPLL, however, was associated with lower postoperative scores and recovery rates. In more than half of the patients the authors documented an increase of kyphosis of less than 2°. Conclusions Patients with a shorter preoperative duration of symptoms and milder myelopathy experienced significantly better postoperative neurological conditions, which indicated that those who present earlier with fewer disabilities should be recommended to undergo surgery in time, although the surgical treatment for OPLL still involves many problems.


2017 ◽  
Vol 2017 ◽  
pp. 1-7
Author(s):  
Alexandros Makis ◽  
Athanasios Gkoutsias ◽  
Theodoros Palianopoulos ◽  
Eleni Pappa ◽  
Evangelia Papapetrou ◽  
...  

Immune thrombocytopenia (ITP) in children has a varied course and according to duration is distinguished as newly diagnosed (<3 months), persistent (3–12), and chronic (>12) types. Several studies have evaluated the prognostic factors for the progression of the disease, but similar works have yet to be performed in Greece. We aimed to identify prognostic markers for the three forms of the disease in 57 Greek children during a 13-year period. Information regarding age, gender, preceding infection, bleeding type, duration of symptoms and platelets at diagnosis, treatment, disease course, and immunological markers was recorded. 39 children had newly diagnosed, 4 persistent, and 14 chronic disease. Chronic ITP children were more likely to be of age > 10 years (p=0.015) and have gradual initiation of the disease (p=0.001), platelets > 10 × 109/L (p=0.01), and impaired immunological markers (p<0.003) compared to newly diagnosed/persistent groups. Recent history of infection was found mainly in the newly diagnosed/persistent group (p=0.013). None of the children exhibited severe spontaneous bleeding. Conclusion. Even though ITP in children usually has a self-limited course, with rare serious bleeding complications, the chronic form of the disease is characterized by different predictive parameters, which can be used in clinical practice.


1999 ◽  
Vol 29 (2) ◽  
pp. 81-84 ◽  
Author(s):  
G Kaeppler ◽  
D Axmann-Krcmar ◽  
I Reuter ◽  
J Meyle ◽  
G Gómez-Román

2021 ◽  
Vol 161 ◽  
pp. S1011-S1012
Author(s):  
F. Kraja ◽  
J. Dervishi ◽  
A. Hoti ◽  
E. Karaulli ◽  
I. Akshija ◽  
...  

Author(s):  
D. Chandrika ◽  
Anantharaju G. S.

<p class="abstract"><strong>Background:</strong> Chronic rhinosinusitis is an extremely prevalent disorder which has significant effect on quality of life of affected individual. Varied symptomatology and varied etiology of unilateral chronic maxillary rhinosinusitis requires a comprehensive approach by otorhinolaryngologist. The objectives of the study were to evaluate the causative factor of unilateral chronic maxillary sinusitis and to study clinical presentation of unilateral chronic maxillary sinusitis<span lang="EN-IN">. </span></p><p class="abstract"><strong>Methods:</strong> 50 patients with symptoms and signs suggestive of unilateral chronic maxillary sinusitis were evaluated. All were subjected to detailed clinical history, ENT examination including complete orodental examination, diagnostic nasal endoscopy, intra oral peri apical radiographs, CT scan of para nasal sinuses<span lang="EN-IN">.  </span></p><p class="abstract"><strong>Results:</strong> Of total of 50 patients studied, gross deviated nasal septum (DNS) is commonest cause of chronic unilateral maxillary sinusitis followed by dental infection of upper premolars<span lang="EN-IN">. </span></p><p class="abstract"><strong>Conclusions:</strong> This study was carried out with an effort to find out etiology of unilateral chronic maxillary sinusitis as identification of etiology will help in successful outcome of the treatment<span lang="EN-IN">.</span></p>


Author(s):  
Saurabh Kothari ◽  
Manjula Kothari ◽  
Shree Mohan Joshi ◽  
Kalp Shandilya

Background: A mass in the right iliac fossa is a common diagnostic problem encountered in clinical practice, requiring skill in diagnosis. Methods: 100 patients with signs and symptoms of right iliac fossa mass admitted in Hospital were identified and were studied by taking detailed clinical history, physical examination and were subjected to various investigations like x ray erect abdomen, chest x-ray, contrast x-ray . Result: In this study of out of 100 cases, 65.00% of cases were related to appendicular pathology either in the form of appendicular mass or appendicular abscess. There were 12.00% cases of ileocaecal tuberculosis. Conclusion: Appendicular lump remains the most common cause for right iliac fossa pain. Ileocaecal tuberculosis is one of the most important differential diagnoses for pain abdomen. Keywords: Appendicular Mass, Ileocaecal Tuberculosis, Carcinoma Caecum, Right Iliac Fossa Mass.


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