scholarly journals Unusual umbilical cord finding in a neonate

2019 ◽  
Vol 6 (6) ◽  
pp. 2685
Author(s):  
Antonieo Jude Raja ◽  
Sriambika K.
Keyword(s):  
Umbilical Cord ◽  
Congenital Anomalies ◽  
Cystic Lesion ◽  
Surgical Intervention ◽  
First Trimester ◽  
Chromosomal Anomalies ◽  
Umbilical Cord Cyst

Umbilical cord cyst refers to any cystic lesion that are associated with the umbilical cord. They are classified as true cysts or pseudocysts. True cysts are small remnants of the allantois, whereas false cysts originate from liquefaction of Wharton Jelly. In present case, cyst was diagnosed at birth without any associated congenital anomalies and resolved spontaneously within a few days requiring nil surgical intervention. Umbilical cord cysts deserve special attention since 20% of them, regardless of type, are associated with structural or chromosomal anomalies. Because of this, fetal karyotyping and amniocentesis should be considered when cysts persist beyond the first trimester.

scholarly journals P25.09: First trimester umbilical cord cyst

2008 ◽  
Vol 32 (3) ◽  
pp. 400-400
Author(s):  
S. R. Kim ◽  
K. D. Ki ◽  
S. Y. Tong ◽  
J. M. Lee ◽  
E. H. Yoo ◽  
...  
Keyword(s):  
Umbilical Cord ◽  
First Trimester ◽  
Umbilical Cord Cyst

scholarly journals Umbilical cord cyst: a diagnostic dilemma

2019 ◽  
Vol 8 (3) ◽  
pp. 1207
Author(s):  
Aayushi Kaushal ◽  
Reeti Mehra ◽  
Sunita Dubey ◽  
Poonam Goel ◽  
Seema Sheokand ◽  
...  
Keyword(s):  
Umbilical Cord ◽  
Cystic Lesion ◽  
Histopathological Examination ◽  
Ultrasound Image ◽  
Final Diagnosis ◽  
Vascular Supply ◽  
Definitive Diagnosis ◽  
Diagnostic Dilemma ◽  
Large Size ◽  
Umbilical Cord Cyst

Umbilical cord cyst refers to any cystic lesion associated with the umbilical cord. Cord cysts can be defined as true or false cysts and may occur in any location along the cord. They are irregular in shape and are located between the cord vessels. Authors are reporting the case of an infant with an umbilical cord tumor which had twice been misdiagnosed previously as a hemangioma, based on ultrasound image of its cystic and solid component with good vascular supply. The ultrasound image most likely suggestive of a hemangioma as a differential diagnosis led to caesarean section in our patient (based on large size of the lesion and fear of rupture of same during process of labour). The definitive diagnosis was made only after birth of the baby. Final diagnosis of true umbilical cord cyst was made after histopathological examination. Thus, there can be confusion in the diagnosis between umbilical cord hemangiomas and umbilical cord cysts based on ultrasound.

Umbilical cord cyst detected in the first trimester by two- and three-dimensional sonography

2006 ◽  
Vol 34 (3) ◽  
pp. 150-152 ◽  
Author(s):  
Hisashi Yonemoto ◽  
Shigeru Itoh ◽  
Yasushi Nakamura ◽  
Katsuyuki Kinoshita,
Keyword(s):  
Umbilical Cord ◽  
Three Dimensional ◽  
First Trimester ◽  
Umbilical Cord Cyst

Allantoic cyst of the umbilical cord detected in the first trimester with good pregnancy outcome

2017 ◽  
Vol 6 (2) ◽  
Author(s):  
Ana Tikvica Luetić ◽  
Dubravko Habek ◽  
Danka Mirić Tešanić
Keyword(s):  
Pregnancy Outcome ◽  
Umbilical Cord ◽  
Chromosomal Aberrations ◽  
Rare Case ◽  
First Trimester ◽  
Spontaneous Resolution ◽  
Ultrasound Finding ◽  
Omphalomesenteric Duct ◽  
Fetal Malformations ◽  
Umbilical Cord Cyst

Abstract Allantoic cysts of the umbilical cord are embryological remnants of either the allantois or the omphalomesenteric duct. These cysts represent a rare ultrasound finding especially in the first trimester. Allantoic cysts can be associated with fetal malformations and chromosomal aberrations or are characterised by spontaneous resolution and good pregnancy outcome. Here we present a rare case of umbilical cord cyst detected by ultrasound in the first trimester with later resolution and favourable pregnancy outcome.

scholarly journals Association between Genetic Variants in NOS2 and TNF Genes with Congenital Zika Syndrome and Severe Microcephaly

Viruses ◽  
2021 ◽  
Vol 13 (2) ◽  
pp. 325
Author(s):  
Julia A. Gomes ◽  
Eduarda Sgarioni ◽  
Juliano A. Boquett ◽  
Ana Cláudia P. Terças-Trettel ◽  
Juliana H. da Silva ◽  
...  
Keyword(s):  
Risk Factors ◽  
Zika Virus ◽  
Genetic Variants ◽  
Educational Level ◽  
Congenital Anomalies ◽  
Family Income ◽  
First Trimester ◽  
In Utero ◽  
Zikv Infection ◽  
Congenital Zika Syndrome

Zika virus (ZIKV) causes Congenital Zika Syndrome (CZS) in individuals exposed prenatally. Here, we investigated polymorphisms in VEGFA, PTGS2, NOS3, TNF, and NOS2 genes as risk factors to CZS. Forty children with CZS and forty-eight children who were in utero exposed to ZIKV infection, but born without congenital anomalies, were evaluated. Children with CZS were predominantly infected by ZIKV in the first trimester (p < 0.001) and had mothers with lower educational level (p < 0.001) and family income (p < 0.001). We found higher risk of CZS due the allele rs2297518[A] of NOS2 (OR = 2.28, CI 95% 1.17–4.50, p = 0.015). T allele and TT/CT genotypes of the TNF rs1799724 and haplotypes associated with higher expression of TNF were more prevalent in children with CZS and severe microcephaly (p = 0.029, p = 0.041 and p = 0.030, respectively). Our findings showed higher risk of CZS due ZIKV infection in the first trimester and suggested that polymorphisms in NOS2 and TNF genes affect the risk of CZS and severe microcephaly.

scholarly journals Investigation of Metronidazole Use during Pregnancy and Adverse Birth Outcomes

2012 ◽  
Vol 56 (9) ◽  
pp. 4800-4805 ◽  
Author(s):  
Catherine A. Koss ◽  
Dana C. Baras ◽  
Sandra D. Lane ◽  
Richard Aubry ◽  
Michele Marcus ◽  
...  
Keyword(s):  
New York ◽  
Birth Weight ◽  
Preterm Birth ◽  
Low Birth Weight ◽  
Congenital Anomalies ◽  
New York State ◽  
Multivariable Analysis ◽  
Preterm Births ◽  
First Trimester ◽  
First Trimester Of Pregnancy

ABSTRACTTo assess whether treatment with metronidazole during pregnancy is associated with preterm birth, low birth weight, or major congenital anomalies, we conducted chart reviews and an analysis of electronic data from a cohort of women delivering at an urban New York State hospital. Of 2,829 singleton/mother pairs, 922 (32.6%) mothers were treated with metronidazole for clinical indications, 348 (12.3%) during the first trimester of pregnancy and 553 (19.5%) in the second or third trimester. There were 333 (11.8%) preterm births, 262 (9.3%) infants of low birth weight, and 52 infants (1.8%) with congenital anomalies. In multivariable analysis, no association was found between metronidazole treatment and preterm birth (odds ratio [OR], 1.02 [95% confidence interval [CI], 0.80 to 1.32]), low birth weight (OR, 1.05 [95% CI, 0.77 to 1.43]), or treatment in the first trimester and congenital anomalies (OR, 0.86 [0.30 to 2.45]). We found no association between metronidazole treatment during the first or later trimesters of pregnancy and preterm birth, low birth weight, or congenital anomalies.

Three-Dimensional Sonographic Evaluation of the Position of the Fetal Conus Medullaris at First Trimester

2021 ◽  
pp. 1-8
Author(s):  
Ruben Ramirez Zegarra ◽  
Nicola Volpe ◽  
Evelina Bertelli ◽  
Greta Michela Amorelli ◽  
Luigi Ferraro ◽  
...  
Keyword(s):  
Abdominal Wall ◽  
Umbilical Cord ◽  
Interobserver Agreement ◽  
Interobserver Variability ◽  
First Trimester ◽  
3D Ultrasound ◽  
Conus Medullaris ◽  
Consecutive Series ◽  
Fetal Life ◽  
Umbilical Cord Insertion

<b><i>Objective:</i></b> The objective of this study was to assess the position of the conus medullaris (CM) at the first trimester 3D ultrasound in a cohort of structurally normal fetuses. <b><i>Methods:</i></b> This was a multicenter prospective study involving a consecutive series of structurally normal fetuses between 11 and 13 weeks of gestation (CRL between 45 and 84 mm). All fetuses were submitted to 3D transvaginal ultrasound using a sagittal view of the spine as the starting plane of acquisition. At offline analysis, the position of the CM was evaluated by 2 independent operators with a quantitative and a qualitative method: (1) the distance between the most caudal part of the CM and the distal end of the coccyx (CMCd) was measured; (2) a line perpendicular to the fetal spine joining the tip of the CM to the anterior abdominal wall was traced to determine the level of this line in relation to the umbilical cord insertion (conus to abdomen line, CAL). Interobserver agreement for the CCMd was evaluated. Linear regression analysis was used to determine the association between the CMCd and CRL, and a normal range was computed based on the best-fit model. The absence of congenital anomalies was confirmed in all cases after birth. <b><i>Results:</i></b> In the study period between December 2019 and March 2020, 143 fetuses were recruited. In 130 fetuses (90.9%), the visualization of the CM was feasible. The mean value of the CMCd was 1.09 ± 0.16 cm. The 95% limits of agreement for the interobserver variability in measurement of the CMCd were 0.24 and 0.26 cm. The interobserver variability based on the intra-class correlation coefficient (ICC) for the CCMd was good (ICC = 0.81). We found a positive linear relationship between the CCMd and CRL. In all these fetuses, the CAL encountered the abdominal wall at or above the level of the cord insertion. <b><i>Conclusion:</i></b> In normal fetuses, the assessment of the CM position is feasible at the first trimester 3D ultrasound with a good interobserver agreement. The CM level was never found below the fetal umbilical cord insertion, while the CMCd was noted to increase according to the gestational age, confirming the “ascension” of the CM during fetal life.

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