scholarly journals Study on prevalence of maternal risk factors, morbidity and mortality in very low birth weight neonates

2021 ◽  
Vol 8 (6) ◽  
pp. 1027
Author(s):  
Ujjwala S. Keskar ◽  
Anjali H. Parekh

Background: Very low birth weight babies with respiratory complications are the commonest reason for admission in NICU. We wanted to identify maternal risk factors associated with it and ways to prevent it. The objective of the current study was to study the prevalence of maternal risk factors, morbidity and mortality in VLBW babies admitted in tertiary care hospital NICU.Methods: Cross sectional observational study performed on all very low birth weight (VLBW) neonates admitted in neonatal intensive care unit of tertiary care hospital attached with Smt. Kashibai Navale medical college, Pune from January 2019 to March 2020.Results: In our study VLBW babies were 2.2% (78/3545). Mean gestational age was 31.15±3.21 weeks; mean birth weight was 1226.24±250.95 grams. Small for gestational age (SGA) babies were 41% and 96% were preterm. Maternal risk factors were present in 61.53% of deliveries, commonest were anaemia in 30.06 % and preeclampsia in 24.35%. Resuscitation at birth was required in 30.76% babies. Morbidity profile showed respiratory distress syndrome in 46.15%, neonatal sepsis in 19.23% and patent ductus arteriosus in 16.66% babies. Overall survival was 74.35%. Prematurity and its complications like RDS requiring surfactant therapy and mechanical ventilation were significant contributors for mortality but only 23.07% mothers were found to have received antenatal steroids in the hospital .Conclusions: Anaemia and preeclampsia were commonly found risk factors present in 61.53% of mothers of VLBW babies. Use of antenatal steroids in mothers should be made compulsory to decrease mortality in VLBW preterm newborns.

2019 ◽  
Vol 8 (1-2) ◽  
pp. 23-30
Author(s):  
Jesmin Jahan ◽  
Md Shameem ◽  
Md Nurul Amin ◽  
Shahzadi Afroza ◽  
Asma Sharmin ◽  
...  

Background & objective: Term low birth weight neonate represents a heavy burden on healthcare services worldwide due to their higher incidence of morbidity and mortality than term normal weight neonates. Certain maternal factors contribute to delivering term low birth weight neonates. This study was designed to identify the proportion of term low birth weight neonates in a tertiary care hospital and their association with maternal risk factors. Methods: This case-control study was carried out in the Department of Obstetrics & Gynaecology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka over a period of 15 months between April 2017 to June 2018. Term low birth weight (< 2500 gm) neonates delivered in Obstetrics Ward were taken as cases, while the term normal weight neonates taken from the same place were controls. A total of 80 cases and 140 controls who met the eligibility criteria were consecutively included in the study. The maternal factors (that may contribute to the development of term LBW neonates) studied were demographic characteristics, past and current obstetric histories and medical conditions or disease during the last pregnancy. Results: In the present study the proportion of term LBW was 18.6% (80 out 430). Univariate analysis showed that housewives and short statured mothers carry 4(95% CI = 1.5 – 11.0) and 2.3(95% CI = 1.3 – 4.1) times higher risk of having term LBW neonates respectively. Of the obstetric characteristics, primipara and pregnant women with inadequate number of ANCs (< 4 visits) were more prone to have term LBW neonates with risk of having the condition being 2.0(95% CI = 1.1 – 3.7) and 2.2(95% CI = 1.0 – 4.9) times respectively. ANC visit in the 2nd or 3rd trimester had 4.5(95% CI = 1.0 – 4.9) times higher risk of delivering LBW neonates compared to those who made their 1st visit in the 1st trimester (p < 0.001). Mothers who maintained a narrow birth spacing (< 2 years) had a significantly more term LBW babies with likelihood of having the condition being 3-fold (95% CI = 1.2 – 7.9) higher than those who maintained an adequate birth spacing (p = 0.011). Hypertension during pregnancy tend to be significantly associated with term LBW neonates with odds of having the condition being 5.4(95% CI = 2.7 – 10.8) times greater than the normotensive ones (p < 0.001). However, after adjustment by binary logistic regression analysis, inadequate ANC, 1st ANC visit in 2nd trimester onwards, and maternal hypertension during pregnancy emerged as independent predictors of term LBW with Odds of having the condition being 3.61(95% CI = 0.65 – 20.17), 7.56(95% CI = 1.52 – 37.5) and 3.7(95% CI = 1.8 – 7.9) with significance values being p = 0.032, p = 0.013 and p < 0.001 respectively. Conclusion: The study concluded that the mothers with inadequate ANC and 1st ANC visit made in 2nd or last trimester and hypertension carry much higher risk of delivering term LBW neonates compared to their respective counterparts in the same population. Ibrahim Card Med J 2018; 8 (1&2): 23-30   


Author(s):  
Pamulaparthi Bindu Reddy ◽  
Gurram Swetha Reddy

Background: Placenta previa refers to the presence of placental tissue that extends over the internal cervical os.  Placenta previa is linked to maternal hypovolemia, anaemia, and long hospital stay and with prematurity, low birth weight, low APGAR score in newborn. So it is very important to identify the condition at an early date to warn the condition thereby reducing the maternal and foetal morbidity and mortality. The present study was aimed to estimate the prevalence of PP, its associated predisposing risk factors and maternal morbidity, mortality and the perinatal outcome.Methods: A prospective observational study for two years was conducted at a tertiary care hospital. Pregnant mothers with >28 weeks of age with H/o ante partum haemorrhage were screened for placenta previa, confirmed by ultra sonography and included in the study. Clinical history, obstetric examination was done and followed up till the delivery. Maternal and foetal outcomes were recorded. Data analyzed by using SPSS version 20.Results: 1.4% incidence of PP was noted, mean age of group was 29.17±1.6 years. Age group of 21-30 years, multiparity Gravida 2-4, previous history of caesarean section and less number of ante natal checkups were significant risk factors and LSCS was most common outcome. Prematurity, low birth weight and APGAR <7 score for 1 minute was common foetal outcomes.Conclusions: Our study strongly suggests foetal surveillance programmes in cases of placenta previa. Measures should be made to bring awareness about PP, in urban slums and to increase medical checkups regularly. Making USG mandatory during every ANC and referral of cases of PP to tertiary care centres would definitely reduce the chances of morbidity and mortality.


2021 ◽  
Vol 41 (1) ◽  
pp. 29-34
Author(s):  
Pareshkumar A Thakkar ◽  
Himanshu G Pansuriya ◽  
Sheela Bharani ◽  
Khushboo Kamal Taneja

Introduction: Mechanical ventilation is an important factor contributing to the reduced neonatal mortality in NICU. However, many ventilated babies are left with detrimental sequelae. This study was undertaken to know the prognostic predictors and survival outcome in the ventilated neonates. We assessed the clinical profile, outcome of mechanical ventilation and analysed the risk factors for mortality and complications resulting from mechanical ventilation. Methods: A prospective study was conducted at the NICU of a tertiary care hospital in India. The study period was from May 2015 to April 2016. Neonates who underwent mechanical ventilation and met the inclusion criteria were enrolled in the study. Their demographic profile, outcomes and risk factors were documented and analysed using appropriate statistical methods. Results: 285 neonates required mechanical ventilation during the study period. Among them, 190 were included in the study. Overall mortality was 99 out of the 190 enrolled (52%). The most common indications for mechanical ventilation were Respiratory Distress Syndrome (RDS), Meconium Aspiration Syndrome (MAS) and apnea. Risk factors contributing significantly to higher mortality of ventilated neonates were very low birth weight (VLBW), gestation of less than 32 weeks, shock, ventilator- associated complications like pneumothorax and pulmonary haemorrhage. In multiple regression analysis, very low birth weight, circulatory disturbances, pneumothorax, pulmonary haemorrhage, and higher initial FiO2 requirement were found to be independent risk factors of mortality. Conclusions: The commonest indications for mechanical ventilation were RDS and MAS. Significantly higher mortality was seen amongst VLBW, preterm neonates. Co-morbidities like circulatory disturbance, and complications like pneumothorax and pulmonary haemorrhage contributed to adverse outcomes.


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