Maternal Risk Factors and Demographic Profile of Neonates Presenting with Persistent Pulmonary Hypertension in a Tertiary care Hospital, Odisha

2019 ◽  
Vol 10 (9) ◽  
pp. 468
Author(s):  
Santosh Kumar Panda ◽  
Manas Kumar Nayak ◽  
Soumini Rath ◽  
Nirmal Kumar Mohakud ◽  
Subhra Snigdha Panda
Keyword(s):  
Risk Factors ◽  
Pulmonary Hypertension ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Persistent Pulmonary Hypertension ◽  
Care Hospital ◽  
Maternal Risk Factors ◽  
Maternal Risk ◽  
Demographic Profile

scholarly journals Study on prevalence of maternal risk factors, morbidity and mortality in very low birth weight neonates

2021 ◽  
Vol 8 (6) ◽  
pp. 1027
Author(s):  
Ujjwala S. Keskar ◽  
Anjali H. Parekh
Keyword(s):  
Risk Factors ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Very Low Birth Weight ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Care Hospital ◽  
Maternal Risk Factors ◽  
Maternal Risk ◽  
Antenatal Steroids

Background: Very low birth weight babies with respiratory complications are the commonest reason for admission in NICU. We wanted to identify maternal risk factors associated with it and ways to prevent it. The objective of the current study was to study the prevalence of maternal risk factors, morbidity and mortality in VLBW babies admitted in tertiary care hospital NICU.Methods: Cross sectional observational study performed on all very low birth weight (VLBW) neonates admitted in neonatal intensive care unit of tertiary care hospital attached with Smt. Kashibai Navale medical college, Pune from January 2019 to March 2020.Results: In our study VLBW babies were 2.2% (78/3545). Mean gestational age was 31.15±3.21 weeks; mean birth weight was 1226.24±250.95 grams. Small for gestational age (SGA) babies were 41% and 96% were preterm. Maternal risk factors were present in 61.53% of deliveries, commonest were anaemia in 30.06 % and preeclampsia in 24.35%. Resuscitation at birth was required in 30.76% babies. Morbidity profile showed respiratory distress syndrome in 46.15%, neonatal sepsis in 19.23% and patent ductus arteriosus in 16.66% babies. Overall survival was 74.35%. Prematurity and its complications like RDS requiring surfactant therapy and mechanical ventilation were significant contributors for mortality but only 23.07% mothers were found to have received antenatal steroids in the hospital .Conclusions: Anaemia and preeclampsia were commonly found risk factors present in 61.53% of mothers of VLBW babies. Use of antenatal steroids in mothers should be made compulsory to decrease mortality in VLBW preterm newborns.

scholarly journals Evaluation of risk factors for perinatal asphyxia in a tertiary care hospital in Bangalore: an observational prospective study

2020 ◽  
Vol 7 (10) ◽  
pp. 1952
Author(s):  
Somashekhar Chikkanna ◽  
Kavya S. ◽  
Saravanan P. ◽  
Nagaraj M. V.
Keyword(s):  
Risk Factors ◽  
Prospective Study ◽  
Perinatal Asphyxia ◽  
Tertiary Care ◽  
Meconium Aspiration Syndrome ◽  
Care Hospital ◽  
Neonatal Seizures ◽  
Maternal Risk Factors ◽  
Maternal Risk ◽  
Observational Prospective Study

Background: Perinatal asphyxia is an insult to fetus or newborn due to lack of oxygen (hypoxia) or lack of perfusion (ischemia) to various organs of sufficient magnitude and duration. Prenatal asphyxia is one of the major causes of early neonatal mortality in India. Our goal was to evaluate risk factors of perinatal asphyxia.Methods: Observational prospective study on 100 babies delivered in our hospital consecutively and requiring resuscitation were included.Results: The mean age of mothers was 23.5 years. 54% neonates were born to primiparous mothers. Anaemia was widely prevalent in the mothers of neonates requiring resuscitation. The major maternal risk factors for newborns requiring resuscitation were pregnancy-induced hypertension (PIH) (46%), oligohydramnios (41%), polyhydramnios (30%) and meconium stained liquor (28%). The fetal factors associated with resuscitation of newborns were intrauterine growth restriction (IUGR) (30%), prematurity (25%), meconium aspiration syndrome (MAS) (20%), and neonatal seizures (36%). Mortality was highest in hypoxic ischemic encephalopathy (HIE) stage 3 with 11%.Conclusions: The most common maternal risk factors for newborns requiring resuscitation was PIH followed by oligohydramnios, polyhydramnios and meconium stained liquor. IUGR was the most common fetal risk factor followed by, prematurity, MAS and neonatal seizures.

scholarly journals Persistent Pulmonary Hypertension of Newborn: Analysis of 494 cases in a Tertiary Care Hospital

2020 ◽  
Vol 38 (4) ◽  
pp. 176-184
Author(s):  
Nurun Nahar Fatema ◽  
Md Ferdousur Rahman ◽  
Ashfaque Ahmmed Khan
Keyword(s):  
Pulmonary Hypertension ◽  
Intensive Care ◽  
Intensive Care Units ◽  
Tertiary Care Hospital ◽  
Low Cost ◽  
Tertiary Care ◽  
Persistent Pulmonary Hypertension ◽  
Care Hospital ◽  
High Flow Oxygen ◽  
Cardiac Intensive Care

Introduction: Persistent pulmonary hypertension (PPHN) or persistent fetal circulation (PFC) is a commonly encountered problem in neonatal and pediatric cardiac intensive care units and cause significant mortality and morbidity. Aim/Objective : To show the outcome of patient of PPHN treated by a cheap, locally available NNF protocol. Methods: It was a retrospective study conducted in pediatric cardiology department of a tertiary care hospital in Dhaka, Bangladesh from February 2014 to March 2019. After diagnosis in noninvasive cardiac laboratory (NIC Lab), all cases were admitted in neonatal and pediatric cardiac intensive care units for specific management using NNF protocol. After 72 hours, echocardiography was repeated, and outcome was analyzed. Results: Out of total 494 cases, 80.56% cases were diagnosed at first week and 4.45% cases were diagnosed at 3rd week of life. Male patients (60.32%) outnumbered female. Babies were delivered by caesarean section in 92.31% cases. PPHN was found alone in 24.69% cases and rest along with other less severe congenital heart diseases. Severe pulmonary hypertension was observed in 63.56% cases. Right ventricular volume was increased in 93.52% cases. Hundred percent neonates were treated with high flow oxygen therapy by optiflow/ nasal cannula/ head box. Antifailure treatment was offered in 73.27% cases, pulmonary vasodilators in 59.51% cases, inotropes in 15.18% cases. Outcome of treatment was analyzed after 72 hours by repeat echocardiography. Four hundred and seventy one (95.34%) cases were cured completely and only 1.01% expired. Conclusion: PPHN is a life threatening condition in neonate only. Early diagnosis and proper management is must for survival. Management by low cost NNF protocol was found effective with 95.34% cure rate and only 1.01% mortality. This protocol may be used for treatment of PPHN in low cost set up. J Bangladesh Coll Phys Surg 2020; 38(4): 176-184

scholarly journals Proportion of Term Low Birth Weight Neonates and Their Association with Maternal Risk Factors in a Tertiary Care Hospital

2019 ◽  
Vol 8 (1-2) ◽  
pp. 23-30
Author(s):  
Jesmin Jahan ◽  
Md Shameem ◽  
Md Nurul Amin ◽  
Shahzadi Afroza ◽  
Asma Sharmin ◽  
...  
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Birth Spacing ◽  
Normal Weight ◽  
Care Hospital ◽  
Maternal Risk Factors ◽  
Maternal Factors ◽  
Maternal Risk

Background & objective: Term low birth weight neonate represents a heavy burden on healthcare services worldwide due to their higher incidence of morbidity and mortality than term normal weight neonates. Certain maternal factors contribute to delivering term low birth weight neonates. This study was designed to identify the proportion of term low birth weight neonates in a tertiary care hospital and their association with maternal risk factors. Methods: This case-control study was carried out in the Department of Obstetrics & Gynaecology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka over a period of 15 months between April 2017 to June 2018. Term low birth weight (< 2500 gm) neonates delivered in Obstetrics Ward were taken as cases, while the term normal weight neonates taken from the same place were controls. A total of 80 cases and 140 controls who met the eligibility criteria were consecutively included in the study. The maternal factors (that may contribute to the development of term LBW neonates) studied were demographic characteristics, past and current obstetric histories and medical conditions or disease during the last pregnancy. Results: In the present study the proportion of term LBW was 18.6% (80 out 430). Univariate analysis showed that housewives and short statured mothers carry 4(95% CI = 1.5 – 11.0) and 2.3(95% CI = 1.3 – 4.1) times higher risk of having term LBW neonates respectively. Of the obstetric characteristics, primipara and pregnant women with inadequate number of ANCs (< 4 visits) were more prone to have term LBW neonates with risk of having the condition being 2.0(95% CI = 1.1 – 3.7) and 2.2(95% CI = 1.0 – 4.9) times respectively. ANC visit in the 2nd or 3rd trimester had 4.5(95% CI = 1.0 – 4.9) times higher risk of delivering LBW neonates compared to those who made their 1st visit in the 1st trimester (p < 0.001). Mothers who maintained a narrow birth spacing (< 2 years) had a significantly more term LBW babies with likelihood of having the condition being 3-fold (95% CI = 1.2 – 7.9) higher than those who maintained an adequate birth spacing (p = 0.011). Hypertension during pregnancy tend to be significantly associated with term LBW neonates with odds of having the condition being 5.4(95% CI = 2.7 – 10.8) times greater than the normotensive ones (p < 0.001). However, after adjustment by binary logistic regression analysis, inadequate ANC, 1st ANC visit in 2nd trimester onwards, and maternal hypertension during pregnancy emerged as independent predictors of term LBW with Odds of having the condition being 3.61(95% CI = 0.65 – 20.17), 7.56(95% CI = 1.52 – 37.5) and 3.7(95% CI = 1.8 – 7.9) with significance values being p = 0.032, p = 0.013 and p < 0.001 respectively. Conclusion: The study concluded that the mothers with inadequate ANC and 1st ANC visit made in 2nd or last trimester and hypertension carry much higher risk of delivering term LBW neonates compared to their respective counterparts in the same population. Ibrahim Card Med J 2018; 8 (1&2): 23-30   

scholarly journals Etiology, outcomes and co-morbidities among cerebral palsy children attending tertiary care hospital, India: a prospective study

2019 ◽  
Vol 6 (3) ◽  
pp. 1023
Author(s):  
N. Dushyanth Subramaniam ◽  
Antony Jenifer ◽  
Uma Devi L. ◽  
Suresh P.
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Cerebral Palsy ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Birth Asphyxia ◽  
Care Hospital ◽  
Maternal Risk ◽  
Prolonged Labour ◽  
History Of

Background: Cerebral palsy is the most common aetiology for motor dysfunction among children worldwide. It is associated with range of co-morbid conditions that affects the quality of life. Cerebral palsy has been studied extensively in western countries and there are only few articles available on epidemiological information in developing countries and low resource settings. This study focuses on the aetiology, risk factors, types and co-morbidities in cerebral palsy.Methods: Cerebral palsy children attending tertiary care hospital were prospectively recruited into the study. The study was conducted during January 2017 to July 2018. The cross-sectional study included complete prenatal, natal and postnatal history of the participants, BERA and Ophthalmological examinations were done.Results: One hundred and fifty children with cerebral palsy were enrolled. The mean age of participants were 36±30 months.  Male to female ratio was 2.19:1. The most common maternal risk factor among study participants was consanguinity in marriage (23.33%). 16% had prolonged labour and 10% had toxaemia during pregnancy. 47% of the children were born by institutional normal vaginal delivery. The most common neonatal risk factor was Birth Asphyxia (23%), low birth weight (20%) and neonatal sepsis (21%). 122 had spastic type of cerebral palsy. The most common morbidity associated with cerebral palsy was Gastro intestinal disturbances in 61% of the participants.Conclusions: History of prolonged labour and birth asphyxia were risk factors for cerebral palsy. Spastic CP is the most common type. Malnutrition, Gross Motor delay, Seizures, Mental retardation were the most common morbidities associated with CP. 

scholarly journals Prevalence of congenital anomalies in babies and associated maternal etiological factors at tertiary care hospital

2021 ◽  
Vol 10 (11) ◽  
pp. 4189
Author(s):  
Shahana I. Chandniwala
Keyword(s):  
Congenital Anomalies ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Care Hospital ◽  
Care Centre ◽  
Maternal Risk Factors ◽  
Tertiary Care Centre ◽  
Cross Sectional ◽  
Maternal Risk ◽  
Factors Associated

Background: The objective of this study was to know the local prevalence of congenital anomaly and study the maternal risk factors associated with it.Methods: Cross sectional descriptive study was carved out. All live babies were examined for presence of congenital anomalies and mother were looked for presence of socio-demographic factor.Results: In this study of 1 year 5767 live birth took place at tertiary care centre out of which 63 babies had congenital anomalies. Therefore, prevalence of congenital anomalies at tertiary care centre was 1.08%.Conclusions: The incidence of malformations were significantly higher in babies born to mothers over the age of 35 years and with parity 4 and above. 

scholarly journals Study of congenital malformations in newborns: a hospital based prospective study

2017 ◽  
Vol 4 (4) ◽  
pp. 1409
Author(s):  
Kinjal G. Patel ◽  
Chintu Chaudhary
Keyword(s):  
Risk Factors ◽  
Cardiovascular System ◽  
Congenital Malformations ◽  
Tertiary Care ◽  
Maternal Diabetes ◽  
Fetal Life ◽  
Care Hospital ◽  
Maternal Risk Factors ◽  
Maternal Risk ◽  
Antenatal Ultrasonography

Background: Congenital malformations represent a defect in the morphogenesis during fetal life. Since the introduction of primary health care and immunization programme, congenital malformations have emerged as one of the commonest cause of perinatal mortality. The objective was to study the incidence, systemic distribution, various maternal risk factors and immediate outcome of congenital malformations in hospital delivered neonates.Methods: This study was conducted at a tertiary care hospital for a period of 2 years. All the hospital delivered live neonates and stillbirth babies with congenital malformations are included in this study. Detailed history, examinations and investigations are carried out to identify etiological factors. Their outcome in form of morbidity and mortality are taken up to their hospital stay.Results: Out of 9600 babies with malformations 171(1.88%) having single malformation and 23(0.25%) having multiple malformations. Incidence of malformations was higher in stillbirths (24.25/1000 livebirths) against than in live births (19.96/1000 livebirths).  The cardiovascular system was involved in 23.4% of babies, followed by musculoskeletal system (22.3%) then gastrointestinal (15.9%) and genitourinary system (15.4%).   Multiple malformations were seen in 11.8% cases. Maternal risk factors associated with malformations were oligohydramnios in 4.12%, previous abortion in 2.5%, eclampsia in 2.5%, polyhydramnios in 1.54%, maternal diabetes in 1.54% and consanguinity in 1.03%. Maximum mortality occurred in babies with gastrointestinal system malformations (56.5%) followed by cardiovascular system malformations (21.7%).  Majority of babies with malformations discharged (78.9%) only 11.8% of babies expired and 2.6% of babies left against medical advice (LAMA).Conclusions: Congenital malformations represent one of the causes of neonatal mortality.  Stillborn babies have higher incidence of malformations. Antenatal ultrasonography and maternal risk factors has important role to identify malformations. Early detection and timely management required to decrease the mortality. 

scholarly journals Clinical profile of hypoglycemia in neonates admitted in neonatal intensive care unit of a tertiary care hospital

2021 ◽  
Vol 8 (2) ◽  
pp. 341
Author(s):  
Sayooj Somanathan ◽  
Sriram Pothapregada ◽  
Anuradha Varadhan ◽  
Ruth Ann Mathew
Keyword(s):  
Risk Factors ◽  
Blood Glucose ◽  
Blood Sugar ◽  
Perinatal Asphyxia ◽  
Tertiary Care ◽  
Clinical Profile ◽  
Care Hospital ◽  
Maternal Risk Factors ◽  
Maternal Risk ◽  
Neonatal Risk Factors

Background: This study was conducted to study the clinical profile of hypoglycemia in newborn and to determine the prevalence of hypoglycemia among neonates admitted in NICU.Methods: All newborns admitted in NICU were examined and those with hypoglycemia (GMR<45 mg/dl) were included in the study and observed. In neonates with risk factors blood sugar was screened at 2, 6, 12, 24, 48 and 72 hours of life or whenever symptoms suggestive of hypoglycemia developed in any neonates and for critically sick neonates blood sugar was screened in every 6 hour in active phase of illness. Any neonates with blood glucose level less than 45 mg/dl were analysed for maternal risk factors, neonatal risk factors and course in the NICU.Results: The prevalence of neonatal hypoglycemia was 14.9% among NICU admissions. The maternal risk factors were GDM, PIH, and PROM. The neonatal risk factors were prematurity, SGA, LGA and comorbid conditions which include perinatal asphyxia, sepsis, polycythemia, shock. The common symptoms were poor feeding, lethargy, jitteriness, convulsions, irritability, hypotonia and cyanosis. Majority of the neonates required only oral feeds for correction of hypoglycemia.Conclusions: Blood glucose screening in neonates with this risk factor is mandatory as many of the neonates were asymptomatic. The importance of early initiation of breast feeding to prevent hypoglycemia should be emphasized. 

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