scholarly journals Incidence of iron deficiency anaemia and it’s early detection in patients with hypoproliferative anaemia presentation in a tertiary care hospital

2018 ◽  
Vol 5 (4) ◽  
pp. 828
Author(s):  
Vishnu Anjan Nareddy ◽  
M. Sai Varun ◽  
Nagabushana M.V.

Background: Iron deficiency anaemia still remains the most common cause of anaemia not only in India but also world over. According to world heath report, there are 1,788,600 people in this world suffering from Iron deficiency anaemia. Iron deficiency anaemia is foremost prevalent disease-causing morbidity in world and therefore it is always absolutely necessary to detect this particular condition in early stages before the eventual development of various dreadful complications like Heart failure and Myocardial infarction. The aim of the study is to find incidence of iron deficiency anaemia in patients with hypo proliferative anaemia presentation, with a possible iron deficient state, by analyzing the haematological and biochemical parameters.Methods: The study was conducted from November 2017 to May 2018 for a period of 6 months which included 50 subjects from both sex groups, aged 20-80 years with the diagnosis of hypo proliferative anaemia.Results: The study results indicate that females (60%) were significantly overrepresented compared to males (40%). Of the 50 subjects 38% were in stage of negative iron balance (stage1) and 32% were in stage of iron deficient erythropoiesis(stage2) and 30% were in normal stage.Conclusions: This Observational study showed a majority of patients with hypo-proliferative anaemia presenting at early stages of negative iron balance and iron deficient erythropoiesis thereby indicating the importance of initiating iron therapy at an early stage even without correlative iron studies.

2019 ◽  
Vol 7 (1) ◽  
pp. 132
Author(s):  
Gaurav Mohan ◽  
Gurinder Mohan ◽  
Manish Chandey ◽  
Avneet Kaur ◽  
Trimaan Singh Sikand ◽  
...  

Background: To study the prevalence and pattern of iron deficiency (ID)in heart failure (HF) patients with or without anaemia.Methods: This is a single-centre observational study, conducted at a tertiary care hospital of Punjab. Patients were selected based on validated clinical criteria-Framingham criteria. The iron parameters were done during the study including serum iron, serum ferritin, total iron binding capacity, and transferrin saturation (TSAT), to diagnose iron deficiency anaemia. Anaemia was defined as haemoglobin (Hb) < 13g/dl in males and <12 g/dL in females, based on WHO definition. Absolute iron deficiency is defined as serum ferritin < 100 mg/L and functional ID was defined as normal serum ferritin (100–300 mg/L) with low TSAT (<20%).Results: A total of 120 patients of Heart Failure (54% males and 46% females) were studied. Most of the patients were of high-functional NYHA class (Class IV NYHA n=45). Iron Deficiency was present in 60% patients with 31.66% patients having absolute and 28.33% patients having functional ID. Nearly one-fifth of the patients were having ID but without anemia, signifying importance of workup of Iron deficiency other than haemoglobin levels.Conclusions: Study highlights the neglected burden of ID in HF patients in India. This study suggests further large-scale studies to better characterize this easily treatable condition and considering routine testing in future Indian guidelines.


2015 ◽  
Vol 35 (1) ◽  
pp. 38-43
Author(s):  
MM Hoque ◽  
ASMNU Ahmed ◽  
H Quaderi

Introduction: Anaemia is a common problem in childhood. In Bangladesh, overall 68% of children aged 6-59 months are anaemic. Anaemia impairs normal growth and development, decreases physical exercise tolerance and intellectual performance in children. The objective of this study was to find out the prevalence and risk factors for iron deficiency anaemia in hospitalized children aged 6 to 36 months.Materials and Methods: Eligible children admitted in Dhaka Shishu (Children’s) Hospital due to any acute illness, were enrolled from 1st June 2010 to 30th August 2010. Anaemia (Hb <11gm/dl) was classified as microcytic, normocytic or macrocytic. Peripheral blood film, serum ferritin, haemoglobin electrophoresis, serum C-reactive protein and stool microscopy were done. Risk factors were looked for in cases of iron deficiency anaemia.Results: Among 331 enrolled children, 201 (61%) had anaemia, among them 63 (31%) had iron deficiency anaemia. Lower the socioeconomic status, higher was the rate of anaemia. Prematurity and low birth weight was significantly associated with anaemia. Poor feeding practices including colostrum rejection, non-exclusive breastfeeding, early/late weaning and inappropriate weaning diet were important risk factors. Gender was not found as a risk factor.Conclusion: A large proportion of hospitalized children under three years of age were found anaemic, among them iron deficiency anaemia was most common. The study result emphasizes the importance of identifying the risk factors of anaemia in this age group. Raising awareness of the problem and providing health and nutrition education will be the key interventions to prevent and control this huge public health problem in Bangladesh.J Nepal Paediatr Soc 2015;35(1):38-43


Author(s):  
Monika . ◽  
Patil Sharmila ◽  
Mahapatra Arun Kumar ◽  
S Rajagopala

Introduction: According to Ayurveda, depletion of Rasa and Rakta Dhatu results in yellowish-white discoloration of body known as Pandu Roga. Its features resemble with IDA (Iron Deficiency Anaemia). It is very common among female adolescents. UNICEF observed that more than half of population of adolescent girls in India are anemic. Lack of knowledge is one of the most significant reason for nutritional problems like anaemia. Aim: To evaluate the level of knowledge, attitude and practices regarding Pandu Roga (Iron Deficiency Anaemia) among female adolescents. Material and Methods: In this study 200 adolescent girls aged between 10 to 16 years visiting Kaumarabhritya OPD, A.I.I.A hospital and nearby government schools were assessed on the basis of a ‘Knowledge, Attitude and Practices (KAP) Questionnaire’ regarding Pandu Roga (IDA). Result: It was found that most of the screened adolescents had poor knowledge of Pandu Roga (IDA), its causes, prevention and management. Discussion: Pandu Roga (IDA) is a dangerous health problem globally, if not attended in time may result into grave outcomes, hence emphasis should be made on its prevention in addition to the cure. Conclusion: There is a need to focus on various health education programs for prevention of nutritional problems like IDA.


KYAMC Journal ◽  
2017 ◽  
Vol 6 (2) ◽  
pp. 631-636
Author(s):  
Md Azizul Hoque ◽  
Khaleda Akhter ◽  
Md Daharul Islam ◽  
Syed Mohammad Monowar Ali ◽  
Md Zillur Rahman ◽  
...  

Background: Anaemia is a common health problem encountered in our day to day medical practice. It occurs in every age groups, in both sexes in every communities and all countries.Objective: To find out the aetiological pattern and clinical profile of severe anaemia for prompt diagnosis an droper management.Materials and Methods: The prospective study was carried out in different Medicine unit at Rajshahi Medical College Hospital (RMCH), Rajshahi on consecutive 100 hospital admitted patients having severe anaemia. All underwent routine and some special investigations for severe anaemia.Results: Peak age incidence was 20-29 years (38%) and sex incidence was male (68%). Most of the patients were farmers (38%). Common monthly income group was >2000-5000 (48%). Incidence of severe anaemia was aplastic (26%), leukaemia (24%), haemolytic (22%), anaemia of chronic disorder (10%), iron deficiency anaemia (9%) and anaemia of chronic renal failure (9%). Peak age incidence for aplastic anaemia was 20- 29 years (42.3%), for leukaemia 14-19 years 33.3%), for haemolytic anaemia 14-19 years (50%), for anaemia of chronic disorder 20-29 and 30-39 years (30% each), iron deficiency anaemia 40-49 years (44.5%) and for anaemia of chronic renal failure 30-39 years (33.3%).Conclusion: Multicentre study with large sample size is warrented to develop more insights about diagnosis and management of severe anaemia.KYAMC Journal Vol. 6, No.-2, Jan 2016, Page 631-636


2021 ◽  
Vol 8 (22) ◽  
pp. 1803-1807
Author(s):  
Anish Kumar Vishal ◽  
Dinesh Bhasin ◽  
Vidhu Dhar Dangwal ◽  
Anurakshat Bhasin

BACKGROUND Anaemia is one of the major public health problems in developing nations. Iron deficiency anaemia (IDA) is the commonest type of anaemia in pregnancy. Parenteral iron therapy is a recommended modality of treatment of IDA. Inj. Ferric Carboxymaltose (FCM) is a dextran free preparation which is safe, easy to deliver and better tolerated. A maximum of 1000 mg can be infused at a time. The present study was intended to assess the efficacy and safety of Inj. FCM in the treatment of iron deficiency anaemia in the second and third trimester. METHODS This prospective study was conducted at a tertiary care centre at Pune. Pregnant women with iron deficiency anaemia of moderate and severe grade were infused 1000 mg of Inj. FCM by longer infusion protocol. A total of 165 pregnant women were included in the study. The efficacy of Inj. FCM was monitored by the rise in the haemoglobin level at 03-, 06- and 08-weeks post infusion of FCM injection and serum Ferritin levels. The safety was assessed by analysing the adverse reactions. RESULTS No serious adverse reaction was recorded in any of the patients. The rise in haemoglobin (Hb) in second and third trimester of moderate and severe grade of anaemia was significant (P < 0.001). The target level of 10 g / dl was achieved in every patient. Only 03 patients received blood transfusion and that was for obstetric indications. No blood transfusion was because of anaemia per se. The rise in serum ferritin level was also statistically significant (P < 0.001). CONCLUSIONS Inj. FCM is an excellent modality to treat iron deficiency anaemia in pregnancy. It is safe and the rise of haemoglobin with correction of anaemia is satisfactory in a short span of time. In our country where only a handful of patients had regular antenatal check-up and non-compliancy and refractory anaemia is rampant, Inj. FCM is a big boon. KEYWORDS Iron Deficiency Anaemia, Inj. Ferric Carboxymaltose, Serum Ferritin, Blood Transfusion


2021 ◽  
Vol 50 (Supplement_2) ◽  
pp. ii8-ii13
Author(s):  
O Meakin ◽  
S Adejumo

Abstract Introduction Iron-deficiency anaemia is a condition that is regularly seen in patients admitted with neck of femur fractures (NOFF) and is associated with increased morbidity peri-operatively. Intravenous ferinject is a method of iron replacement that leads to a more rapid increase in haemoglobin than oral replacement, therefore is often more favourable in this patient group, leading to better patient outcomes. Method A quality improvement project was undertaken. An initial audit was conducted to analyse the demographic of patients with NOFF and to assess the current practice of the orthogeriatric team when managing iron deficiency anaemia. This reviewed NOFF patients admitted in July 2017. The indications and benefits of ferinject were distributed to the medical team, encouraging use clinically, and a further audit was performed 2 years later to compare outcomes and practice, reviewing patients with NOFF admitted July–September 2019. Results It was found that 87% of patients with NOFF are iron-deficient on admission, and that introducing the use of ferinject meant that 50% fewer blood transfusions were required. Additionally, it highlighted that those who received ferinject during their admission had a smaller range of discharge haemoglobin levels than those who did not. Finally, it was found that the use of ferinject did not affect the rates of readmission in the assessed patient cohort. Conclusions The introduction of the use of ferinject in NOFF patients with iron-deficiency anaemia leads to a reduction in the requirement of blood transfusions required and to a reduction of the range of discharge haemoglobin levels. Ferinject therefore aids in improved recovery of NOFF patients. It does not, however, appear to have any effect on readmission rates in this patient group. Further education is required amongst the orthogeriatric team about the indications and benefits of ferinject to ensure that all eligible patient receive ferinject, improving their recovery.


Author(s):  
Chintan Upadhyay ◽  
Nisha Upadhyay

Background: Iron deficiency anaemia during pregnancy leads to preterm birth, low birth weight and small-for-gestational age babies and increases incidence of postpartum haemorrhage (PPH) and the reason for the incidence of PPH is higher in India compared with the rest of the world. The objective of this study was to find association between maternal anaemia and neonatal complications and to find long term morbidity and mortality of babies born to anaemic mothers.Methods: It is a prospective study done at Obstetrics and Gynecology Department, Dr. B. R. Ambedkar Medical College and Hospital, Bangalore during October 2009 to October 2011. All subjects were analyzed in full details and haemoglobin estimation done during 1st visit, at 30th week and 36th week of gestation.Results: Study observed moderate anaemia observed in almost 53.0% cases followed by mild (29.5%) and severe (17.5%) respectively. Risk factors present in 58.0% cases and maternal complications in puerperium observed in 14.5% cases. High incidence of adverse foetal outcome in the form of preterm (20%), IUGR (28%), NICU admission (25.5%) and IUD (3%) seen in present study. Study found association between space between pregnancy, LSCS and fetal outcome with severity of anaemia. Ensuring maternal iron sufficiency during gestation is the most cost-effective method of preventing perinatal iron deficiency and related morbidities.Conclusions: Iron supplementation during pregnancy in iron deficient mothers improves iron status during pregnancy and postpartum period, thus providing some protection against iron deficiency in the subsequent pregnancy. Proper antenatal care is the basic requirement for prevention, early detection and treatment of anaemia.


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