scholarly journals A retrospective study on palmoplantar psoriasis and its associations in a tertiary care centre

Author(s):  
Saradha K. Perumal ◽  
Sudha R. Gopinath

<p class="abstract"><strong>Background:</strong> Psoriasis is a chronic immune mediated inflammatory condition of the skin. Palmoplantar psoriasis (PPP) is a clinical variant of plaque psoriasis affecting palms and soles extending to the wrist and the margins of the soles and heels. This study was done to find out the prevalence of palmoplantar psoriasis in our setting. The aim of the study was to determine the prevalence, demographic features and other co-morbidities of the palmoplantar plaque psoriasis in a tertiary care centre.</p><p class="abstract"><strong>Methods:</strong> We conducted retrospective study for a period of one year (January 2017 to December 2017) on palmoplantar plaque psoriasis patients attending the dermatology OPD.<strong></strong></p><p class="abstract"><strong>Results:</strong> Among 552 enrolled psoriasis patients, 85 were clinically diagnosed to have palmoplantar psoriasis. The mean age of the patient was 45 years. Most of them belong to 4<sup>th</sup>, 5<sup>th </sup>and 6<sup>th</sup> decade of life. The male to female ratio was 1:2.26. The duration of the disease was more than one year in 73% of patients at the study time. Occupation of the patients included house-wives (50%), manual labourers (36%) and office goers, (13%). Hyperkeratotic plaque type psoriasis with scaling and fissures was the predominant morphological pattern recorded. Dyslipidemia (22%), overweight and obesity (56%), hypothyroidism (6%) and diabetes mellitus (12%) were the observed co-morbidities in this study.</p><p class="abstract"><strong>Conclusions:</strong> The prevalence of palmoplantar psoriasis (0.09%) was low in our study. Palmoplantar psoriasis affected middle aged adults and had a female predominance in this study. Overweight, obesity, dyslipidemia, diabetes mellitus and hypothyroidism were the co-morbid conditions observed in this study. Being a relapsing and chronic condition the disease poses a poor quality of life than plaque type psoriasis.</p>

Author(s):  
Shairoly Singh ◽  
Ishan Arora ◽  
Shireen Singh

Background: In India, a large majority of blood donors are deferred due to anemia. Anemia is a temporary cause of deferral which can be easily treated. Deferrals due to anemia can be easily identified in blood bank and can be treated and managed effectively.Methods: A retrospective study was carried out in Department of Blood Bank of Pt. Jawahar Lal Nehru Govt. Medical College, Chamba (H.P) over a time period of one year from 1st Jan 2017 to 31st Dec 2017.Results: We observed that the total number of deferrals was 90 out of all blood donors forming 9%. Out of all deferrals, those due to anemia were 23 (25.5%). Prevalence of anemia in female donors is much higher, constituting 26.31% and anemia in male donors in our study is lower forming 1.8%.Conclusions: Our study concluded that percentage of anemia is much higher in females than males. Educating and counseling females about prevention and treatment of anemia would help in lowering the percentage of anemia in females in our community.


2021 ◽  
Vol 8 (13) ◽  
pp. 773-777
Author(s):  
Piyush Arora ◽  
Himanshu Mittal ◽  
Neeraj Gupta ◽  
Jose K. Jimmy ◽  
Khushboo Jain ◽  
...  

BACKGROUND Covid-2019, caused by severe acute respiratory syndrome-coronavirus-2 (SARS CoV2), is an ongoing pandemic that emerged from China in November 2019. It has affected millions of people worldwide causing significant morbidity and mortality. We wanted to analyse the clinical and demographic profile of Covid-19 patients admitted in a tertiary-care-centre in the central part of Rajasthan, compare their characteristics with other studies published from parts of NorthernIndia and identify factors associated with delayed recovery and mortality. METHODS This was a retrospective observational analysis of the clinical features, and epidemiological profile of Covid-19 positive patients admitted at a tertiary-carecentre in the Central part of Rajasthan. RESULTS A total of 422 patients was enrolled in the study. The male: female ratio was 1.34 with a mean age of 34.1 years. Almost 195 (46.2 %) patients were in the age group of 20 - 40 years. Respiratory diseases were the most common co-morbidity seen in 36 patients (8.53 %), diabetes-mellitus in 28 patients (6.63 %), hypertension in 22 patients (5.2 %). Fever was the commonest presenting symptom (N = 98, 77.17 %), followed by cough (N = 85, 66.93 %), and breathlessness (N = 51, 45.67 %). Factors significantly associated with mortality were age group of 60 - 80 year (P < 0.001), presence of co-morbidities (P < 0.001) and history of smoking & alcohol consumption (P < 0.001). Among co-morbidities diabetes-mellitus, hypertension, chronic-respiratory-diseases & chronic-kidneydiseases had significant impact on mortality. Absence of co-morbidity, lack of addiction and symptoms at the time of presentation were associated with an earlier conversion of reverse transcription polymerase chain reaction (RT-PCR) report. CONCLUSIONS Clinical spectrum of COVID 19 varies widely. Presence of comorbidities, addiction, radiological features has a drastic impact on mortality and duration of infectivity. KEYWORDS SARS CoV-2, Covid-19, RT PCR, Coronavirus


2021 ◽  
Vol 12 (e) ◽  
pp. 1-6
Author(s):  
Astha Sharma ◽  
Ashok K Khare ◽  
Lalit K Gupta ◽  
Asit Mittal ◽  
Sharad Mehta ◽  
...  

Background: An association between lichen planus and systemic disorders such as diabetes mellitus, dyslipidemia and metabolic syndrome has been reported. Aim: To assess the clinico-epidemiological profile of lichen planus, evaluate prevalence of underlying metabolic complications and compare the clinical profile of patients with and without metabolic syndrome. Material and methods: All the patients with lichen planus attending dermatology out patient department of a tertiary care centre in South Rajasthan over a period of one year were studied. Patients with lichenoid drug eruptions and those receiving systemic treatment for lichen planus were excluded from the study. Statistical analysis was done using the chi – square test. A p value < 0.05 was considered significant. Results: A total of 270 patients of lichen planus were enrolled. Male to female ratio was found to be 0.76: 1. Maximum (64; 23.7%) patients belonged to the age group of 31 – 40 years. Classical morphology was the most common (128; 47.4%) cutaneous pattern. Mucosal and nail involvement was seen in 80 (29.6%) and 87 (32.2%) patients respectively. Koebner phenomenon was present in 57 (21.1%) patients. The investigations were completed by 175 (64.8%) patients. Diabetes mellitus and hypertension were found in 12.6% (22/175) and 14.3% (25/175) patients respectively. The diagnostic criteria for dyslipidemia and metabolic syndrome were fulfilled by 39.4% (69/175) and 27.4% (48/175) patients respectively. Majority (81.2%) of the patients with metabolic syndrome belonged to age group 40 years and above, and oral and nail involvement was found to be more common in them. It is recommended that these patients should be screened for complications like diabetes, hypertension, dyslipidemia and metabolic syndrome. Conclusion: Significant numbers of lichen planus patients were found to have dyslipidemia and metabolic syndrome. Patients aged 40 years and above, with oral and nail involvement have higher propensity to be associated with metabolic syndrome and therefore such patients should be screened for metabolic complications. Timely screening and early intervention may reduce the risk of related morbidity and mortality. Limitations: Lack of control group is the drawback of our study. Age and sex matched comparative studies are required for confirmation of the results.


Author(s):  
Navya Sri Sreenivas ◽  
Saraswathi Sakranaik ◽  
Ranganath Thimmanahalli Sobagiah ◽  
Anil Kumar

Background: Rabies is a viral zoonosis. In up to 99% of cases, domestic dogs are responsible for rabies virus transmission to humans. About 30% of the victims of dog bites are children under the age of 15. Ironically, all these problems are preventable by effective vaccination. However, for an ef­fective prevention programme, it is important to un­derstand the epidemiology of animal bite cases. The objective of the study was to assess the epidemiological pattern of animal bite cases attending anti-rabies clinic. Methods: A record based retrospective study was conducted from April to May 2016 by reviewing the records of one year in anti-rabies clinic. Results: In the study out of 2850 bite victims, 78% were males and about 21, 54% were in the age group of 20-29 years. 97% of cases were bitten by dog. Based on area wise distribution majority of the bite victims were from Bangalore west (49.5%), among them 23% was referred for Immunoglobulin. The study also showed that majority of paediatric cases were reported more during the month of April and May. Conclusions: In our study we found that majority of cases were reported among the paediatric age group during summer vacations. Hence education should be given in the community as well in schools for primary prevention of animal bite. 


2012 ◽  
Vol 32 (2) ◽  
pp. 142-145 ◽  
Author(s):  
B Sigdel ◽  
R Nepali

Introduction: Ear diseases are common in children mainly due to altered anatomy of Eustachian tube which is straighter in children as compared to that in adults. However, the cause of hearing loss in children is more varied, including the etiologies. This study was done to find out the pattern of ear diseases in paediatric age group attending ear, nose and throat OPD in a tertiary care centre in Pokhara, Nepal. Materials and Methods: This is a prospective study done in paediatric patients attending ENT OPD over a period of one year from January 2010 to January 2011. The diagnoses were made on the basis of history and clinical examination. Results were expressed in numbers and percentages. Results: Out of 1632 Pediatric ENT patients, 944 had ear diseases, 59.2% were males and 40.8% females. Wax (33.4%) was the commonest diagnosis followed by Chronic suppurative otitis media (24.3%) and Acute ottitis media (13%). Conclusion: Ear diseases are most common condition in ENT OPD among paediatric age group. Wax, CSOM and ASOM were the three most common ear diseases. J. Nepal Paediatr. Soc. 32(2) 2012 142-145 doi: http://dx.doi.org/10.3126/jnps.v32i2.5673


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