scholarly journals Role of anterior segment optical coherence tomography in the evaluation of microbial keratitis

2021 ◽  
Vol 7 (3) ◽  
pp. 548-553
Author(s):  
Isha Chaturvedi ◽  
Kamaljeet Singh ◽  
Jagriti Rana ◽  
Kshama Dwivedi ◽  
Reena Sachan
Keyword(s):  
Optical Coherence Tomography ◽  
Corneal Thickness ◽  
Anterior Segment ◽  
Morphological Characteristics ◽  
Objective Evaluation ◽  
Response To Treatment ◽  
Optical Coherence ◽  
Microbial Keratitis ◽  
The Mean

Anterior segment optical coherence tomography (AS-OCT) is a newer technology that provides two-dimensional images of corneal infiltration. This study was undertaken to assess whether AS-OCT can aid objective evaluation and response to treatment in resolving microbial keratitis. This prospective study was performed on 17 patients of who underwent slit lamp and AS-OCT examination at presentation and follow up on days 3, 7, 14, 28 and 6 weeks. A standardized scanning protocol was used to measure the corneal thickness (CT) and infiltrate thickness (IT) using the caliper tool of a commercially available AS-OCT device. The mean CT in the infiltrated area and mean IT, both were thickest at presentation (710.88 um and 288.76 um respectively). The mean CT decreased to 665.12 µm, 650.24 µm, 584.35 µm, 549 µm, 507.47 µm on days 3, 7, 14, 28 and 6 weeks respectively. Similarly, the mean IT decreased to 287.24 µm, 244.41 µm, 197 µm, 174.59 µm and 154.82 µm. Paired t- test was used to calculate the statistical change in CT and IT, which was significant (p<0.0001) at 6 weeks, at the rate of 0.67% and 1.01% per day. AS-OCT can show morphological characteristics of microbial keratitis and give quantitative assessment at every follow up.

scholarly journals Correlation between Central Corneal Thickness and Degree of Myopia among Malaysian Patients Undergoing Laser Keratorefractive Surgery

2020 ◽  
pp. 52-58
Author(s):  
Sagili Chandrasekhara Reddy ◽  
Mohd Mansor Shariff ◽  
Aina Malindri Dasrilsyah
Keyword(s):  
Optical Coherence Tomography ◽  
Refractive Surgery ◽  
Central Corneal Thickness ◽  
Corneal Thickness ◽  
Anterior Segment ◽  
Military Hospital ◽  
Moderate Degree ◽  
Optical Coherence ◽  
Corneal Refractive Surgery ◽  
The Mean

Purpose: To determine the central corneal thickness in myopic adult patients scheduled for laser corneal refractive surgery and to explore its correlation with degree of refractive error. Materials and Methods: The case records of 130 myopic patients who underwent laser corneal refractive surgery in a military hospital over a period of two years were reviewed to determine the central corneal thickness. All patients had 6/6 vision with best correction, and did not have any other anterior segment or fundus diseases in both eyes. The central corneal thickness was measured with Visante Carl Zeiss anterior segment optical coherence tomography instrument.                                                                                                                        Results: Out of 130 patients, males were more (73, 56.2%); mean age of patients was 33.8 years (range 18-60 years) and majority were Malays (110, 84.6%).  The spherical power of myopia ranged from – 0.5 to – 10.00 D, and the cylindrical power ranged from – 0.25 to – 3.25 D. The mean central corneal thickness of both eyes was 528.2 µm (range 331- 615 µm); in the mild degree of myopia (- 0.50 to - 2.00 D) 527.9 µm, moderate degree (- 2.25 to -5.00 D) 529.4 µm, and high degree (-5.25 to -11.00 D) 523.9 µm. Conclusion: The anterior segment optical coherence tomography provides noncontact, rapid, pachymetry mapping of the corneal thickness. In Malaysian patients, the mean central corneal thickness of both eyes in myopia was 528.1 µm (range 331- 615 µm). There was no correlation between the mean central corneal thickness and degree of myopia, different genders, age groups, ethnic groups and two eyes.

scholarly journals Morphometric evaluation and measurements of primary pterygium by anterior segment optical coherence tomography and its relation with astigmatism

2021 ◽  
Vol 13 ◽  
pp. 251584142110201
Author(s):  
Anuradha Raj ◽  
Renu Dhasmana ◽  
Harsh Bahadur
Keyword(s):  
Optical Coherence Tomography ◽  
Corneal Thickness ◽  
Anterior Segment ◽  
Cross Sectional Study ◽  
Optical Coherence ◽  
Cross Sectional ◽  
Horizontal Length ◽  
The Mean ◽  
The Relationship ◽  
Primary Pterygium

Purpose: To evaluate the relationship between measurements and various morphometric parameters of primary pterygium on anterior segment optical coherence tomography(AS-OCT) and refractive and keratometric astigmatism. Methods: In this cross-sectional study, patients with primary pterygium were included. The AS-OCT parameters of pterygium consisting of epithelial thickness near apex(µm), apical or head thickness(µm), its thickness at limbus(µm), horizontal length of pterygium(mm), central corneal thickness (µm) and maximum pterygium thickness(mm) were evaluated. Results: Sixty three patients comprising of 63 eyes with a primary pterygium were studied. The mean keratometric and refractive astigmatism were 1.69 ± 3.15 Diopter(D) and0.5 ± 1.4D, respectively. There was a significant association between pterygium grade and stocker’s line with keratometric astigmatism ( p = 0.02, 0.00) respectively. Vertical and horizontal length on slit lamp and horizontal length on AS-OCT showed significant association with keratometric astigmatism ( p = 0.05, 0.00,0.00), respectively. Limbal thickness on AS-OCT showed significant positive correlation with refractive astigmatism ( r = 0.29, p = 0.02). Conclusion: The pterygium grade influences the keratometric astigmatism. Increased limbal thickness of pterygium on AS-OCT leads to more refractive astigmatism.

Anterior Segment Optical Coherence Tomography Imaging in Peripheral Ulcerative Keratitis, a Corneal Structural Description

2020 ◽  
Author(s):  
Clemence BONNET ◽  
Louis Debillon ◽  
Saba Al-Hashimi ◽  
Florence Hoogewoud ◽  
Dominique Monnet ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Systemic Vasculitis ◽  
Corneal Thickness ◽  
Anterior Segment ◽  
Case Series ◽  
Structural Description ◽  
Optical Coherence ◽  
Peripheral Ulcerative Keratitis ◽  
The Mean ◽  
Ulcerative Keratitis

Abstract Background Anterior-segment optical coherence tomography (AS OCT) is an important tool, helpful to diagnose and manage many corneal conditions, but has not been reported in cases of peripheral ulcerative keratitis (PUK). The aim of this study is to describe AS OCT findings in cases of PUK. Methods Retrospective observational case series of six eyes with a PUK with proven systemic vasculitis. Clinical course, slit lamp photographs, and AS OCT findings were the main outcomes. Results The AS OCT findings were found to correlate with the ocular disease’s level of activity. In the acute stage, an absence of corneal epithelium, a scrambled appearance of the anterior stroma and a heterogeneous stromal reflectivity were observed. During the reduction of disease level activity, an irregular hyporeflective epithelium, a smoother anterior stroma, and a homogenous hyperreflective stroma were seen. At the healed stage, a filling of the corneal defect by a hyporeflective thick epithelium, the persistence of the hyperreflective underlying stroma, and a demarcation line were observed. The mean total corneal thickness at last follow-up was significantly thicker (509 ± 147 µm) compared with the mean corneal thickness at onset (408 ± 131 µm; P = 0.03). Conclusions AS OCT provides an assessment of structural changes occurring in PUK, useful for its diagnosis and monitoring.

Real-Time Assessment of Intraoperative Vaulting in Implantable Collamer Lens and Correlation with Postoperative Vaulting

2016 ◽  
Vol 27 (1) ◽  
pp. 21-25 ◽  
Author(s):  
Jeewan S. Titiyal ◽  
Manpreet Kaur ◽  
Suman Sahu ◽  
Namrata Sharma ◽  
Rajesh Sinha
Keyword(s):  
Optical Coherence Tomography ◽  
Real Time ◽  
Anterior Segment ◽  
Optical Coherence ◽  
Implantable Collamer Lens ◽  
Paired Samples ◽  
Snellen Visual Acuity ◽  
Intraoperative Optical Coherence Tomography ◽  
The Mean

Purpose To assess the intraoperative vaulting in patients undergoing implantable collamer lens (ICL) implantation with microscope-integrated intraoperative optical coherence tomography (iOCT) and correlate it with the postoperative vaulting. Methods Forty eyes of 22 consecutive patients undergoing ICL implantation were prospectively evaluated. Vaulting was measured intraoperatively using microscope-integrated iOCT. The ICL-lenticular relationship was dynamically assessed throughout the surgery. Postoperative vaulting was measured using anterior segment optical coherence tomography on the first postoperative day and after 1 month and compared with the intraoperative vaulting. Uncorrected and best-corrected Snellen visual acuity, intraocular pressure (IOP), and anterior and posterior segments were assessed in all cases. Results The mean central vaulting noted intraoperatively was 558.4 ± 122.8 µm. Postoperative mean vaulting was 576.0 ± 131.2 µm on day 1 and 551.1 ± 122.5 µm on day 30. There was a significant correlation between the intraoperative and the postoperative day 1 vaulting (paired samples correlation: 0.969, p<0.001) and day 30 vaulting (paired samples correlation: 0.945, p<0.001). An ICL-lenticular touch was not noted at any time during the surgery. The postoperative course was uneventful and no patient developed raised IOP or lenticular changes by the last follow-up. Conclusions Intraoperative vaulting correlates well with postoperative vaulting and can aid in on-table detection of extremes of vaulting and decision-making. It enhances the safety of the surgical procedure by providing a real-time display of the intraoperative manipulations.

scholarly journals Anterior Segment Biometry with Phenylephrine and Tropicamide during Accommodation Imaged with Ultralong Scan Depth Optical Coherence Tomography

2019 ◽  
Vol 2019 ◽  
pp. 1-5
Author(s):  
Junna Zhang ◽  
Yang Ni ◽  
Peng Li ◽  
Wen Sun ◽  
Mengyun Liu ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Corneal Thickness ◽  
Anterior Segment ◽  
Anterior Chamber Depth ◽  
Crystalline Lens ◽  
Repeated Measurements ◽  
Optical Coherence ◽  
Posterior Surface ◽  
Optical Zone

Purpose. To investigate the influence of phenylephrine and tropicamide on anterior segment biometry with ultralong scan depth optical coherence tomography (UL-OCT) during accommodation. Methods. In this study, 20 left eyes of healthy volunteers with a mean ± standard deviation age of 31.05 ± 5.84 years and a mean refraction of −1.16 ± 1.11 diopters (range 0∼−3.0 D) were imaged using UL-OCT after instillation of artificial tears, phenylephrine, and tropicamide in three follow-up trials, respectively. At each follow-up trial, two repeated measurements were performed at states of relax and 5D accommodative stimulation. The dimensional parameters included central corneal thickness (CCT), anterior chamber depth (ACD), pupil diameter (PD), lens thickness (LT), and horizontal radii of the lens anterior and posterior surface curvatures (LAC and LPC). Results. Tropicamide led to larger pupil, deeper ACD, thinner LT, and flatter crystalline lens surface (P<0.05). Phenylephrine induced an increase in PD (P<0.05), while no significant changes were seen in ACD, LT, LAC, and LPC (P>0.05). CCT did not change after both phenylephrine and tropicamide instillation in this study (P>0.05). Tropicamide induced the loss of accommodation and phenylephrine achieved pupil dilation without affecting the accommodation. PD, ACD decreased, LT increased significantly and the anterior and posterior surface of the lens in a 6.294 mm of diameter optical zone became steeper during accommodation after administration of phenylephrine (P<0.05). Conclusion. The anterior segment physiology changed after tropicamide instillation. Besides, tropicamide induced the loss of accommodation and phenylephrine preserved the accommodation with a larger pupil. And, the anterior and posterior surface of lens in a 6.294 mm of diameter optical zone became steeper during the accommodation.

Utility of the Anterior Segment Optical Coherence Tomography for Measurements of Central Corneal Thickness

2007 ◽  
Vol 48 (12) ◽  
pp. 1643 ◽  
Author(s):  
Hyoung Sub Shim ◽  
Chul Young Choi ◽  
Hee Gyung Lee ◽  
Myoung Joon Kim ◽  
Hung Won Tchah
Keyword(s):  
Optical Coherence Tomography ◽  
Central Corneal Thickness ◽  
Corneal Thickness ◽  
Anterior Segment ◽  
Optical Coherence

scholarly journals The Use of Anterior-Segment Optical-Coherence Tomography for the Assessment of the Iridocorneal Angle and Its Alterations: Update and Current Evidence

2021 ◽  
Vol 10 (2) ◽  
pp. 231
Author(s):  
Giacinto Triolo ◽  
Piero Barboni ◽  
Giacomo Savini ◽  
Francesco De Gaetano ◽  
Gaspare Monaco ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Intraocular Pressure ◽  
Clinical Relevance ◽  
Anterior Segment ◽  
Angle Closure ◽  
Current Evidence ◽  
Optical Coherence ◽  
Iridocorneal Angle ◽  
Wide Range

The introduction of anterior-segment optical-coherence tomography (AS-OCT) has led to improved assessments of the anatomy of the iridocorneal-angle and diagnoses of several mechanisms of angle closure which often result in raised intraocular pressure (IOP). Continuous advancements in AS-OCT technology and software, along with an extensive research in the field, have resulted in a wide range of possible parameters that may be used to diagnose and follow up on patients with this spectrum of diseases. However, the clinical relevance of such variables needs to be explored thoroughly. The aim of the present review is to summarize the current evidence supporting the use of AS-OCT for the diagnosis and follow-up of several iridocorneal-angle and anterior-chamber alterations, focusing on the advantages and downsides of this technology.

scholarly journals Changes in anterior segment optical coherence tomography following pars plana vitrectomy without tamponade

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Alireza Khodabande ◽  
Massood Mohammadi ◽  
Hamid Riazi-Esfahani ◽  
Shahab Karami ◽  
Massood Mirghorbani ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Anterior Chamber ◽  
Pars Plana Vitrectomy ◽  
Anterior Segment ◽  
Anterior Chamber Depth ◽  
Optical Coherence ◽  
Mean Values ◽  
Iop Measurement ◽  
Pars Plana ◽  
The Mean

Abstract Background To evaluate changes in anterior segment morphology on anterior segment optical coherence tomography (AS-OCT) following pars plana vitrectomy (PPV) without tamponade. Methods Patients who underwent PPV without tamponade for epiretinal membrane were evaluated. Eligible patients underwent intraocular pressure (IOP) measurement and AS-OCT preoperatively as well as 1 month and 6 months post-operatively. Anterior chamber width (ACW), anterior chamber depth (ACD), trabecular iris angle (TIA), angle opening distance at 500 and 750 µm (AOD), and trabecular iris space area at 500 and 750 µm (TISA) at four quadrants were recorded and analyzed. Additionally, the mean values of TIA (MTIA), AOD (MAOD), and TISA (MTISA) for each eye (mean of four quadrants) were analyzed. Results 23 patients completed the study. The mean age of participants was 56.4 ± 3.6 years of age and 13/23 (56%) were female. Mean IOP of patients was 18.1 ± 1.1, 18.3 ± 1.1, and 18.1 ± 1.2 preoperatively,1 month post-operatively, and 6 months post-operatively, respectively. (p = 0.83). No difference was detected post-operatively in measurements of ACW, ACD, MTIA, MAOD500, MAOD750, MTISA500, and MTISA750. Conclusion Pars plana vitrectomy without tamponade was not associated with changes in anterior chamber morphology.

Spontaneous attachment of complex Descemet’s membrane detachment following multiple failed interventions

2021 ◽  
Vol 14 (8) ◽  
pp. e243960
Author(s):  
Shikha Gupta ◽  
Karthikeyan Mahalingam ◽  
Tushar Agarwal
Keyword(s):  
Optical Coherence Tomography ◽  
Anterior Segment ◽  
Corneal Transplant ◽  
Optical Coherence ◽  
Initial Attempt ◽  
Ocular Tissues ◽  
Surgical Interventions ◽  
Complicated Cataract ◽  
First Time

We describe a case with complex Descemet membrane detachment (DMD) which persisted despite initial two failed surgical attempts to appose the ocular tissues. However, over time, tissue alignment was obtained spontaneously. A 60-year-old woman, operated trabeculectomy, had a total DMD intraoperatively during a complicated cataract surgery. Initial attempt to DM repositioning with intracameral air injection failed. Anterior Segment Optical Coherence Tomography (ASOCT) showed detachment of both DM and pre-Descemet’s layer (PDL). After consultation with a corneal surgeon, patient was again attempted for Intra-operative Optical Coherence Tomography (iOCT)-guided settlement of DMD with intracameral air which again failed. So, the patient was registered for lamellar corneal transplant, but at 3 months follow-up, DM had spontaneously attached, confirmed on ASOCT. This case shows for the first time that even complex DMDs involving PDL, can spontaneously appose despite failed surgical interventions.

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