scholarly journals Colonic ganglioneuromatous polyposis in a 6-year-old girl – A case report and review of literature

2021 ◽  
Vol 6 (4) ◽  
pp. 325-327
Author(s):  
Reshma M ◽  
G. Sathibai Panicker ◽  
Reeba Mary Issac

Ganglioneuroma of the gastrointestinal tract is a rare mesenchymal tumor of neural origin, especially in childhood. They are categorized into three different morphological subtypes, namely, polypoid ganglioneuroma, ganglioneuromatous polyposis (GP), and diffuse ganglioneuromatosis. Patients with ganglioneuromas have different presentations depending on the location, extent, and size of the lesion. We report here a case of colonic ganglioneuromatous polyposis, presenting as abdominal pain and chronic constipation in a 6‑year‑old girl. Although GP cases are reported in adult age group, cases in pediatric age group are rare. Only a few cases are reported in the literature of GP in the pediatric age group. Although rare, this disorder must be taken into consideration in the differential diagnosis in every patient with symptoms such as abdominal pain, constipation, and lower intestinal bleeding, to avoid a delayed diagnosis.

2016 ◽  
Vol 3 (4) ◽  
pp. 169-174 ◽  
Author(s):  
Kiran Khedkar ◽  
Hemanshi Shah ◽  
Charu Tiwari ◽  
Deepa Makhija ◽  
Mukta Waghmare

2021 ◽  
Vol 12 (11) ◽  
pp. 133-138
Author(s):  
Sumita Pal ◽  
Basudha Roy ◽  
Amrit Chattopadhyay ◽  
Akhila Andra ◽  
Gautam De

Background: Dengue is one of the most widespread arthropod borne diseases worldwide with an annual incidence of 50–100 million cases per year. The recent resurgence of dengue in the pediatric population has created concern among pediatricians, especially due to increased incidence of atypical features, leading to delayed diagnosis and increased mortality. There are few studies regarding this due to under reporting of the cases. Aims and Objectives: This study aims to study the clinical profile and outcome of dengue patients between the age groups of 1 month and 12 years with special emphasis on patients with atypical features. Dengue patients with atypical presentation are easily misdiagnosed by physicians, especially in the pediatric age group which increases the morbidity and mortality. Materials and Methods: This was a retrospective observational study conducted from May 2018 to September 2019 in the Department of Pediatrics, CNMCH. All pediatric patients who were dengue IgM or dengue NS1 positive were included in the study and their course of stay was followed through hospital records. The data were statistically analyzed through SPSS 16.0 software. Results: Sixty-two dengue patients were included in the study. Thirty-two patients presented as mild febrile illness, classical dengue fever (DF), dengue hemorrhagic fever, or shock syndrome without atypical manifestations. Atypical manifestations were found in 30 patients (48.38%) of our study. Eleven (17.7%) patients had splenomegaly, 5 (8.1%) patients had hepatitis, 3 (4.8%) patients had diarrhea, 2 (3.2%) patients had acalculous cholecystitis, 1 (1.6%) patient had hepatitis with acalculous cholecystitis, 1 (1.6%) patient had hepatitis with diarrhea, 1 (1.6%) patient had myocarditis, 1 (1.6%) patient had paroxysmal supraventricular tachycardia, 1 (1.6%) patient had acute pancreatitis, 1 (1.6%) patient had acute kidney injury, 1 (1.6%) patient had ARDS, 1 (1.6%) patient had encephalitis, and 1 (1.6%) patient had myositis. Need of intensive care facility was more in patients with atypical manifestations due to mis or late diagnosis which prolonged course of stay. Conclusion: Atypical manifestations of DF are more common than reported. Lack of awareness among physicians, especially in primary health center, leads to delayed diagnosis and increased mortality and morbidity.


2017 ◽  
Vol 12 (4) ◽  
pp. 371
Author(s):  
LuisRafael Moscote-Salazar ◽  
GuruDutta Satyarthee ◽  
Hector Farid-Escorcia ◽  
WillemGuillermo Calderon-Miranda ◽  
HuberSaid Padilla-Zambrano ◽  
...  

1990 ◽  
Vol 12 (1) ◽  
pp. 25-30
Author(s):  
Andrew V. Atton ◽  
Walter W. Tunnessen

The differential diagnosis of alopecia in the pediatric age group is simplified by the fact that 90% to 95% of the cases are caused by four major entities: alopecia areata, telogen effluvium, tinea capitis, and trichotillomania. Careful examination of the scalp, hair, and historical pattern of the loss will usually be rewarded by the correct diagnosis.


2016 ◽  
Vol 11 (1) ◽  
pp. 105
Author(s):  
Jayendra Kumar ◽  
Anand Prakash ◽  
Viraat Harsh ◽  
Anil Kumar

2011 ◽  
Vol 2011 ◽  
pp. 1-4 ◽  
Author(s):  
J. Bouguila ◽  
K. Brahim ◽  
M. Mokni ◽  
K. Skandrani ◽  
A. Harbi ◽  
...  

Malacoplakia is a form of chronic granulomatous inflammatory reaction that rarely affects the pediatric age group. The gastrointestinal system is the second most common site for the occurrence of malacoplakia. We report the case of a 9-year-old girl who was hospitalized for abdominal pain, chronic diarrhea, and rectal hemorrhage. The endoscopic examinations and histopathology confirmed the diagnosis of intestinal malacoplakia. We successfully treated her with oral levofloxacin. This disease does not have any specific clinical or biological signs, and the diagnosis is exclusively based on histology.


2016 ◽  
Vol 9 (1) ◽  
pp. 59 ◽  
Author(s):  
Radha Shenoy ◽  
Milind Suryawanshi ◽  
Roshini Isaac ◽  
SanthoshK Philip

2021 ◽  
Vol 27 (1) ◽  
pp. 63-71
Author(s):  
Maria Consiglia Trotta ◽  
Roberto Alfano ◽  
Giovanna Cuomo ◽  
Ciro Romano ◽  
Antonietta Gerarda Gravina ◽  
...  

OBJECTIVE To compare the timing of serum anti-drug antibodies in adult and pediatric age groups, males and females, treated for inflammatory bowel disease or arthritis with adalimumab or infliximab by retrospectively combining data collected during a 2-year therapeutic drug monitoring period. METHODS Four hundred thirty sera were divided in groups collected at 0, 3, 6, 12, and 24 months (T0, T3, T6, T12, and T24) after initiation of therapy and assayed for drug and relative anti-drug antibodies levels. At each time point, the percentage of sera presenting anti-drug antibodies, as well as the drug concentrations, were calculated and correlated with patient age and sex. RESULTS Anti-drug antibodies were present in 31.5% of sera and were significantly higher in the pediatric age group than in the adult age group, through all time points. The percentages of sera showing anti-drug antibodies were significantly different as early as 3 months and were sera from pediatric female group. The percentages of sera showing anti-drug antibodies reached the highest value at 6 months in the pediatric age group and at 12 months in the adult age group. CONCLUSIONS Sera from pediatric had an earlier presence of anti-drug antibodies than adults. In particular, pediatric females sera showed the fastest anti-drug antibodies development.


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