scholarly journals Recurrent verrucous carcinoma of the foot: A case report

2016 ◽  
Vol 1 (1) ◽  
Author(s):  
Jayabal Pandiaraja ◽  
Selvaraju Uthayam
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Verrucous Carcinoma ◽  
Surgical Margin ◽  
Metastatic Potential ◽  
History Of ◽  
Forefoot Amputation ◽  
Slow Growing

<p>Verrucous carcinoma is an uncommon, locally invasive and slow growing squamous cell carcinoma of the skin and mucous membrane. The proposed causative agent for verrucous carcinoma is human papillomavirus (HPV). It has low metastatic potential compared to squamous cell carcinoma. This is a report of a 75-year-old male admitted with history of growth over the forefoot. Histopathological examinations confirmed verrucous carcinoma and the patient underwent forefoot amputation with 2 cm clear surgical margin. During the 4th month of follow-up, the patient developed a lesion at the post-operative site which was proven as a recurrence. Even though it carried low metastatic potential, it needed repeated resection or amputation because of high local recurrence.</p><p> </p>

scholarly journals ORAL VERRUCOUS CARCINOMA: A REPORT OF THREE CASES

2014 ◽  
Vol 4 ◽  
Author(s):  
Smit Singla ◽  
Raghavendra Kini ◽  
Vathsala Naik ◽  
Anjali Shetty
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Buccal Mucosa ◽  
Verrucous Carcinoma ◽  
Metastatic Potential ◽  
Epidermoid Carcinoma ◽  
Low Grade ◽  
Pathological Features ◽  
Slow Growing

Ackerman’s tumor is a low grade variant of oral Verrucous carcinoma (VC) or squamous cell carcinoma (OSCC). Although it occurs in other anatomic sites, most intraoral cases involve buccal mucosa, alveolar mucosa and gingiva. The typical features of VC that differ from the usual oral epidermoid carcinoma is it generally slow growing, chiefly exophytic and superficially invasive at until late in the course of the disease and have low metastatic potential. This paper presents three variable cases of oral VC along with their clinical and histo-pathological features.

scholarly journals Oral findings during follow-up of nasopharyngeal squamous cell carcinoma treatment: A case report

2021 ◽  
Vol 9 ◽  
pp. 2050313X2110330
Author(s):  
Atsushi Musha ◽  
Nobuteru Kubo ◽  
Naoko Okano ◽  
Hidemasa Kawamura ◽  
Yuhei Miyasaka ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Concurrent Chemoradiotherapy ◽  
Nasopharyngeal Cancer ◽  
Inflammatory Conditions ◽  
Positron Emission ◽  
History Of ◽  
Oral Area

A 50-year-old woman with a long history of nasopharyngeal cancer (T2N2M0, squamous cell carcinoma) underwent chemoradiotherapy and surgery. In the past, to prevent tumor recurrence or metastasis, she underwent concurrent chemoradiotherapy or neck dissection. However, during a follow-up 10 years after the surgery, intense F-18 fluorodeoxyglucose uptake was detected in the oral area (SUVmax 6.0). A biopsy of the area with F-18 fluorodeoxyglucose uptake revealed pathological inflammation. Radiography showed the presence of a wisdom tooth, located at the F-18 fluorodeoxyglucose accumulation site, and pericoronitis of this tooth was detected. Our findings indicate the importance of considering the effect of inflammatory conditions, such as periodontal disease, in using F-18 fluorodeoxyglucose positron emission tomography/computed tomography during follow-up after head and neck cancer treatment.

Transoral laryngeal microsurgery for early-stage laryngeal basaloid squamous cell carcinoma

2021 ◽  
Vol 14 (12) ◽  
pp. e245746
Author(s):  
Barbara Verro ◽  
Carmelo Saraniti
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Early Stage ◽  
Basaloid Squamous Cell Carcinoma ◽  
Neck Node ◽  
History Of ◽  
Node Metastases ◽  
Basaloid Squamous

A 71-year-old man presented to our otolaryngology clinic with dysphagia and dyspnoea. He had a history of smoking for 40 years. Laryngoscopy showed an exophytic, round mass on the left aryepiglottic fold that was entirely excised by transoral laser CO2 microsurgery. Histological assessment revealed a pT1 basaloid squamous cell carcinoma (BSCC) with free-margin resection. He underwent close follow-up and after 3-year follow-up, the patient was free from disease. Laryngeal BSCC is a rare cancer with poor prognosis due to its late diagnosis and early neck node metastases. We report a rare case of early tumour treated by endoscopic surgery without complications or recurrence of disease. However, knowing this type of cancer and making a correct differential diagnosis are important to guarantee the best therapy and prognosis.

Mo1033 Natural History of Superficial Head and Neck Squamous Cell Carcinoma Under Follow-Up Endoscopic Observation With Narrow Band Imaging

2016 ◽  
Vol 83 (5) ◽  
pp. AB436
Author(s):  
Hiroshi Nakamura ◽  
Tomonori Yano ◽  
Satoshi Fujii ◽  
Tomohiro Kadota ◽  
Toshifumi Tomioka ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Natural History ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Narrow Band ◽  
Narrow Band Imaging ◽  
Endoscopic Observation ◽  
History Of

Verrucous Squamous Cell Carcinoma of the Larynx: Evidence for Increased Metastatic Potential after Irradiation

1987 ◽  
Vol 97 (4) ◽  
pp. 381-384 ◽  
Author(s):  
Staffan Edström ◽  
Sonny L. Johansson ◽  
Jörgen Lindström ◽  
Ingemar Sandin
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Verrucous Carcinoma ◽  
Metastatic Potential ◽  
Tumor Stage ◽  
Squamous Cell Carcinomas ◽  
Rare Type ◽  
Regional Metastases ◽  
Verrucous Squamous Cell Carcinoma

Verrucous squamous cell carcinoma is a rare type of well-differentiated squamous cell carcinoma with a characteristic morphologic appearance and specific clinical behavior. It has been claimed that this tumor may undergo dedifferentiation after radiotherapy; this will result in a more aggressive behavior. From 1968 to 1980, we have diagnosed and treated 569 squamous cell carcinomas of the larynx. Fourteen of them were reported to exhibit verrucous features macroscopically. These tumors were histopathologically reexamined. All 569 cases were stratified with regard to tumor stage (≤T2 N0 M0) and treatment (irradiation). Six patients of 340 were then diagnosed as having verrucous squamous cell carcinomas, according to the Ackerman criteria. The patients were followed for at least 5 years and regional metastases of poorly differentiated carcinoma developed in at least two patients in the verrucous carcinoma group within 2 1/2 years after full-dose irradiation. Among the patients with nonverrucous carcinoma, this frequency was estimated to be 3%. This study provides evidence that metastatic spread that occurs after irradiation is approximately 10 times more frequent ( p < 0.05) for T1–2 laryngeal verrucous carcinomas, as compared to the common type of squamous cell carcinoma.

scholarly journals Conjunctival Inverted Papilloma Progressing to Carcinoma. First Report in Horse

2021 ◽  
Vol 8 (6) ◽  
pp. 108
Author(s):  
Vito Biondi ◽  
Annamaria Passantino ◽  
Michela Pugliese ◽  
Salvatore Monti ◽  
Alessandra Sfacteria ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Inverted Papilloma ◽  
Ophthalmological Examination ◽  
First Report ◽  
Arabian Horse ◽  
History Of ◽  
The Right

A five-year-old, entire female Arabian horse with a 6-month history of a non-painful nodule on the conjunctiva of the right eye was evaluated. Ophthalmological examination showed a firm, smooth and fleshy conjunctival mass that raised the suspicion of a conjunctival neoplasm. Histological evaluations showed that the mass was composed of an endophytic growth consisting of numerous long papillary projections of hyperplastic stratified squamous epithelium supported by thin fibrovascular stalks. Typical features of squamous cell carcinoma with disorganized cell growth and infiltration of surrounding tissues were detectable within the mass. Inverted papilloma progressing to carcinoma was diagnosed. Follow-up examination showed that no local recurrence was present during the 12-month follow-up period. To the authors’ knowledge, this is the first report describing the inverted papilloma in the horse and, due to its progression to squamous cell carcinoma, warns about the inclusion of the inverted papilloma in the differential diagnosis of conjunctival neoplasm and driven treatments.

scholarly journals Primary Corneal Squamous Cell Carcinoma in a Dog: Clinical and Histopathological Evaluation

2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Giovanni Barsotti ◽  
Lorenzo Ressel ◽  
Riccardo Finotello ◽  
Veronica Marchetti ◽  
Francesca Millanta
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Keratoconjunctivitis Sicca ◽  
Neoplastic Cells ◽  
Ki 67 ◽  
Clinical Investigations ◽  
History Of ◽  
P53 Immunoreactivity

An 8-year-old male pug with a 12-month history of a progressive nonpainful mass on the left cornea was evaluated. Ocular examination showed a severe bilateral keratoconjunctivitis sicca, pigmentary keratitis, and an exophytic irregular pink mass occupying approximately 75% of the total corneal surface of the left eye. A squamous cell carcinoma (SCC) was suspected on cytology, and clinical investigations showed no evidence of metastases. A transpalpebral enucleation was therefore performed, and the diagnosis of SCC was confirmed on histopathology. Immunohistochemical investigations showed that the neoplastic cells were pan-cytokeratin positive and vimentin negative. Additionally, nuclei immunoreactive to Ki-67 antigen were detected. Tumor cells were also negative to p53. Immunoreactivity to COX-2 was found in less than 10% of the neoplastic cells. No adjuvant therapies were instituted, and no evidence of local recurrence or distance metastasis was identified during the 24-month follow-up period.

scholarly journals Unique Presentation of Squamous Cell Carcinoma as Giant Cutaneous Horn

2019 ◽  
Vol 103 (9-10) ◽  
pp. 505-508
Author(s):  
Mohammad Fazelul Rahman Shoeb ◽  
Sanna Adappa
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Local Excision ◽  
Squamous Cell ◽  
Wide Local Excision ◽  
Verrucous Carcinoma ◽  
Histopathologic Examination ◽  
Unique Case ◽  
Cutaneous Horn

Cutaneous horn is a conical, dense, and hyperkeratotic protrusion that often appears similar to the horn of an animal. Giant cutaneous horns are rare; no incidence or prevalence has been reported. The significance of cutaneous horns is that they occur in association with, or as a response to, a wide variety of underlying benign, premalignant, and malignant cutaneous diseases. Herein we report a unique case of a 60-year-old male with a giant cutaneous horn (size: 10 cm × 2 cm) projecting from the left angle of mouth, which is extremely rare. Wide local excision of the growth was done. Histopathologic examination showed verrucous carcinoma with negative margin. There is no recurrence after follow-up of 2 years.

scholarly journals Long-term follow-up of a Patient with Malignant Transformation of Inverted Papilloma into Sinonasal Undifferentiated Carcinoma

2017 ◽  
Vol 8 (3) ◽  
pp. ar.2017.8.0209 ◽  
Author(s):  
Carolyn A. Orgain ◽  
Terry Y. Shibuya ◽  
Lester D. Thompson ◽  
David B. Keschner ◽  
Rohit Garg ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Malignant Transformation ◽  
Squamous Cell ◽  
Undifferentiated Carcinoma ◽  
Sinonasal Undifferentiated Carcinoma ◽  
Postnasal Drip ◽  
Nasal Tumors ◽  
History Of

Introduction Inverted papillomas (IP) are benign sinonasal neoplasms, which account for 0.5–4% of all nasal tumors. IPs have been known to transform into squamous cell carcinoma in 5–15% of cases. Rarely, transformations to other malignancies have been reported. Here we report a unique case of malignant transformation of an IP into sinonasal undifferentiated carcinoma (SNUC). Methods A case report with a literature review; institutional review board exempted. The clinical presentation, radiographic features, surgical intervention, histopathologic analysis, treatment, and outcome of the case were examined. Results A 62-year-old man presented with a 3-month history of nasal airway obstruction, rhinorrhea, and postnasal drip refractory to medical therapy. He had a long history of exposure to fumes, chemicals, dusts, and solvents as a professional painter as well as a 45 pack-year history of smoking and alcohol abuse. The patient was ultimately found to have a left ethmoidal IP with a focus of malignant transformation into SNUC. Endoscopic resection was performed, followed by concurrent chemoradiation and adjuvant chemotherapy. After surgery, he had no evidence of recurrent disease after 9 years of follow-up. Conclusions IP is known to transform into squamous cell carcinoma. Here we report a rare case of malignant transformation into SNUC, a much more uncommon and aggressive lesion. Although traditionally associated with a poorer prognosis, the positive outcome for SNUC observed in this patient may potentially be attributed to early detection and timely therapeutic intervention.

scholarly journals A Troubling Diagnosis of Verrucous Squamous Cell Carcinoma (“the Bad Kind” of Keratosis) and the Need of Clinical and Pathological Correlations: A Review of the Literature with a Case Report

2011 ◽  
Vol 2011 ◽  
pp. 1-4 ◽  
Author(s):  
A. Santoro ◽  
G. Pannone ◽  
M. Contaldo ◽  
F. Sanguedolce ◽  
V. Esposito ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Cavity ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Verrucous Carcinoma ◽  
Metastatic Potential ◽  
Low Grade ◽  
Biological Behaviour ◽  
Chewing Tobacco ◽  
Verrucous Squamous Cell Carcinoma

Verrucous carcinoma (also known as Ackerman tumor) is an uncommon exophytic low-grade well-differentiated variant of squamous cell carcinoma. This neoplasm typically involves the oral cavity, larynx, genitalia, skin, and esophagus. It is well known for its locally aggressiveness and for its clinically slow-growing behaviour with minimal metastatic potential. Verrucous carcinoma of oral cavity is so closely aligned with the use of snuff and chewing tobacco that it has been called the “snuff dipper's cancer”. Recent studies have proved the role of HPV. The typical clinical presentation of oral verrucous carcinoma has long been known, as its remarkably innocuous appearance and biological behaviour. In this work, we report a review of the scientific literature and describe a troublesome case of oral verrucous cancer.

Sign in / Sign up

Export Citation Format

Share Document