scholarly journals Prevalence of Weak D (Du) in Blood Donors in a Referral Teaching Hospital

2017 ◽  
Vol 6 (2) ◽  
pp. 1509
Author(s):  
H. S. Lamba ◽  
Kulbir Kaur ◽  
Kulwant Kaur ◽  
Amarjit Singh Vij
Keyword(s):  
Patient Care ◽  
Blood Group ◽  
Teaching Hospital ◽  
Blood Donors ◽  
Blood Product ◽  
Blood Group Antigen ◽  
Abo Blood Group ◽  
Blood Samples ◽  
Donor Population ◽  
Gel Technique

<p><strong>Background:</strong> Rh D is the most important Blood Group antigen after ABO Blood group antigen for transfusion purpose. All negative blood units by routine methods must be tested to detect weak D using IAT method. When the test for D and D<sup>u</sup> is positive, the label should read Rh(D) Positive . When the test for D and D<sup>u</sup> is negative, the label should read Rh(D) Negative.</p><p><strong>Objective:</strong> To know the prevalence of weak D in the donor population. No study has been done in this part of the country earlier. It will help in the knowledge of weak D, which is very important for better patient care and prevent allo-immunzation in blood recipients.</p><p><strong>Materials and Methods:</strong> Blood samples were tested by ID Gel technique or by tube method with two anti D reagents - anti-D IgM monoclonal and blend of anti-D IgM&amp;amp;IgG. All negative samples were further tested for weak D in IAT phase by LISS/Coombs' gel card.</p><p><strong>Results:</strong> A total of 13043 samples were tested from January 2011 to December 2013. 12196 were Rh positive and 847 were Rh D negative. Weak D was positive in 8 samples.</p><p><strong>Conclusion:</strong> The study shows the prevalence of weak D as 0.07% in blood donors who were primarily from in and around Jalandhar in Punjab. These donors may have posed problem to the recipients of blood and blood product and their detection prevented them from alloimunisation.</p>

scholarly journals Prevalence of Ca Blood Type and Alloantibodies in a Population of Horses from Italy

Animals ◽  
2020 ◽  
Vol 10 (7) ◽  
pp. 1179
Author(s):  
Daniela Proverbio ◽  
Roberta Perego ◽  
Luciana Baggiani ◽  
Francesco Ferrucci ◽  
Enrica Zucca ◽  
...  
Keyword(s):  
Clinical Practice ◽  
Blood Group ◽  
Blood Donors ◽  
Blood Groups ◽  
Blood Type ◽  
Blood Products ◽  
Blood Typing ◽  
Blood Samples ◽  
Gel Technique ◽  
Whole Blood Samples

A knowledge of the blood groups and alloantibodies present is essential for the safe transfusion of blood products in horses. Pre-transfusion screening and blood typing minimizes the risk of incompatible RBC transfusions and prevents immunization of the recipient against incompatible RBC antigens. The frequencies of blood groups can vary among different breeds. Knowledge of a breed’s blood group prevalence can be very useful for identifying the best blood donors during transfusion in clinical practice. The aims of this study were to estimate the prevalence of the Ca blood type in horses from Italy using a monoclonal immunocromatographic method and to estimate the prevalence of anti-Ca alloantibodies in Ca− horses using agglutination on gel technique. Ca blood type was determined on 110 whole blood samples. The prevalence of the Ca+ blood type was 79.1%. This study also provides data about the prevalence of Ca+ blood group in Italian Saddle Horses (77,3%) and Dutch Warmblood (58,3%). No significant association was found between Ca blood type and sex with 79.5% and 78.8% of females and males testing Ca+, respectively. The total number of Ca− samples with detectable anti-Ca alloantibodies was 7/23 (30.4%).

scholarly journals Estimating the Risk of ABO Hemolytic Disease of the Newborn in Lagos

2015 ◽  
Vol 2015 ◽  
pp. 1-5 ◽  
Author(s):  
Alani Sulaimon Akanmu ◽  
Olufemi Abiola Oyedeji ◽  
Titilope Adenike Adeyemo ◽  
Ann Abiola Ogbenna
Keyword(s):  
Blood Group ◽  
Teaching Hospital ◽  
Blood Donors ◽  
University Teaching ◽  
Abo Blood Group ◽  
Hemolytic Disease ◽  
Gene Frequencies ◽  
Abo Incompatibility ◽  
Population Prevalence ◽  
Abo Hemolytic Disease

Background. ABO hemolytic disease of the newborn is the most common hemolytic consequence of maternofetal blood group incompatibility restricted mostly to non-group-O babies of group O mothers with immune anti-A or anti-B antibodies. Aim. We estimated the risk of ABO HDN with view to determining need for routine screening for ABO incompatibility between mother and fetus. Materials and Methods. Prevalence of ABO blood group phenotypes in blood donors at the donor clinic of the Lagos University Teaching Hospital and arithmetic methods were used to determine population prevalence of ABO genes. We then estimated proportion of pregnancies of group O mothers carrying a non-group-O baby and the risk that maternofetal ABO incompatibility will cause clinical ABO HDN. Results. Blood from 9138 donors was ABO typed. 54.3%, 23%, 19.4%, and 3.3% were blood groups O, A, B, and AB, respectively. Calculated gene frequencies were 0.1416, 0.1209, and 0.7375 for A, B, and O genes, respectively. It was estimated that 14.3% of deliveries will result in a blood group O woman giving birth to a child who is non-group-O. Approximately 4.3% of deliveries are likely to suffer ABO HDN with 2.7% prone to suffer from moderately severe to severe hemolysis.

scholarly journals ABO, Rhesus blood groups and transfusion-transmitted infections among blood donors in Gabon

2018 ◽  
Vol 13 (1) ◽  
pp. 12 ◽  
Author(s):  
Christ-Dominique Ngassaki-Yoka ◽  
Jophrette Mireille Ntsame Ndong ◽  
Cyrille Bisseye
Keyword(s):  
Blood Group ◽  
Blood Donor ◽  
Representative Sample ◽  
Blood Donors ◽  
Blood Groups ◽  
Abo Blood Group ◽  
Blood Group Antigens ◽  
Abo Blood Groups ◽  
Donor Population ◽  
Monospecific Antisera

Background: Few studies focused on the study of blood groups in Gabon. This study aimed to determine the phenotypic frequency of ABO and Rhesus antigens in blood donors of Libreville and to assess the association between ABO blood groups and transfusion-transmitted infections.Materials and Methods: The study of ABO and Rhesus blood groups concerned 4,744 blood donors. ABO and Rhesus phenotyping were obtained using monoclonal monospecific antisera: anti-A, anti-B, anti-AB, anti-D, anti-E, anti-C, anti-c, and anti-e with an automate (QWALYS® 3, DIAGAST, France) or a card gel (ID Card, BIO-RAD) according to manufacturer’s instructions.Results: The phenotypic frequency of blood group antigens A, B, AB and O were respectively 21.0%; 17.6%; 2.6% and 58.9%. Those of rhesus antigens D, d, C, c, E and e were 97.7%; 2.3%; 15.9%; 99.9%; 17.6%; 99.3%, respectively. The prevalence of ABO and Rh antigens in Gabonese donors reported here are significantly different from those of neighboring countries. No association was found between the prevalence of HIV, HCV and syphilis and ABO blood groups. Instead, HBV seroprevalence was twice as high among non-O blood groups donors compared with blood group O donors [OR = 2 (CI 1.26 to 3.2), p = 0.003].Conclusions: This study provides new data on phenotypic frequency of ABO and Rh blood groups in a representative sample of the Gabonese blood donor population. It suggests a significant association between ABO blood group and HBV infection.

scholarly journals Assessing ABO/Rh Blood Group Frequency and Association with Asymptomatic Malaria among Blood Donors Attending Arba Minch Blood Bank, South Ethiopia

2016 ◽  
Vol 2016 ◽  
pp. 1-7 ◽  
Author(s):  
Getaneh Alemu ◽  
Mohammedaman Mama
Keyword(s):  
Blood Group ◽  
Malaria Infection ◽  
Blood Donors ◽  
Blood Groups ◽  
High Rate ◽  
Abo Blood Group ◽  
Asymptomatic Malaria ◽  
Abo Blood Groups ◽  
Group Frequency ◽  
Rh Blood Group

Background. Determination of the various ABO/Rh blood group distributions and their association with malaria infection has paramount importance in the context of transfusion medicine and malaria control. Methods. Facility based cross-sectional study was conducted from February to June, 2015, to assess ABO/Rh blood groups distribution and their association with asymptomatic malaria. A structured questionnaire was used to collect data. Blood grouping was done using monoclonal antibodies. Thin and thick blood films were examined for Plasmodium parasites. Data were analyzed using SPSS version 20.0. Results. A total of 416 blood donors participated with median age of 22±0.29 (median ± standard error of the mean). Distribution of ABO phenotypes, in decreasing order, was O (175, 42.1%), A (136, 32.7%), B (87, 20.9%), and AB (18, 4.3%). Most of them were Rh+ (386, 92.8%). The overall malaria prevalence was 4.1% (17/416). ABO blood group is significantly associated with malaria infection (P=0.022). High rate of parasitemia was seen in blood group O donors (6.899, P=0.003) compared to those with other ABO blood groups. Conclusion. Blood groups O and AB phenotypes are the most and the least ABO blood groups, respectively. There is significant association between ABO blood group and asymptomatic malaria parasitemia.

scholarly journals ABO Blood Group Antigen on the Human Liver Ribosome

1970 ◽  
Vol 46 (3) ◽  
pp. 301-304 ◽  
Author(s):  
Shigenori IKEMOTO ◽  
Tanemoto FURUHATA
Keyword(s):  
Blood Group ◽  
Human Liver ◽  
Blood Group Antigen ◽  
Abo Blood Group

ABO blood group and risk of cancer: A register-based cohort study of 1.6 million blood donors

2016 ◽  
Vol 44 ◽  
pp. 40-43 ◽  
Author(s):  
Senthil K. Vasan ◽  
Jinseub Hwang ◽  
Klaus Rostgaard ◽  
Olof Nyrén ◽  
Henrik Ullum ◽  
...  
Keyword(s):  
Cohort Study ◽  
Blood Group ◽  
Blood Donors ◽  
Abo Blood Group ◽  
Risk Of Cancer

Influence of ABO blood group on von Willebrand factor tests in healthy Saudi blood donors

2018 ◽  
Vol 29 (2) ◽  
pp. 211-215 ◽  
Author(s):  
Abdullah Alharbi ◽  
Salwa Bakr Hassan ◽  
Abdul-Kareem Al-Momen ◽  
Khalid Al-Saleh ◽  
Rasheed Nasr ◽  
...  
Keyword(s):  
Blood Group ◽  
Von Willebrand Factor ◽  
Blood Donors ◽  
Abo Blood Group ◽  
Von Willebrand ◽  
Willebrand Factor

scholarly journals Frequency of ABO and Rhesus blood groups in Saudi healthy blood donors versus non-Saudi in a retrospective study in Makkah City

2021 ◽  
Vol 1 (1) ◽  
pp. 2-13
Author(s):  
Amal z. Moustafa ◽  
Mohammed S. Aldosari ◽  
Talat A. AL-Bukhari ◽  
Younis A. Allohibi ◽  
Shirin H . Teama ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Blood Group ◽  
Blood Donors ◽  
Blood Groups ◽  
Abo Blood Group ◽  
Sri Lankan ◽  
Blood Storage ◽  
Blood Group A ◽  
Group A ◽  
Makkah City

Purpose: to assess the frequency of ABO and Rh blood groups among Saudi and non-Saudi healthy blood donors and to compare between them. Methods: A retrospective study was conducted; in Makkah City, Saudi Arabia. It included 15,365 participants of 44 nationalities who have attended the blood bank of King Abdul Aziz Hospital. The collected data were age, sex, nationality, ABO, and Rhesus blood groups.  Results: 46.8 % of the participants were O, 28.8 % A, 19.5 % B, and 4.9% AB. The nationalities with a higher frequency of blood group O were Saudi, Mauritanian, Yemeni, Thai, Malian, Sudanese, Jordanian, Indian, Moroccan, Somali, Malaysian, Indonesian, Myanmar, Nigerian, Pakistani, Bangladeshi, Algerian, Djibouti, Burkinabe, Eritrean, Ghanaian, Bahraini, Bosnian, Canadian, Gambian, Iraqi, and Sri Lankan. Those with a higher frequency of blood group A were Turkish, Palestinian, Syrian, Lebanese, Egyptian, Afghan, Chadian, French, Tunisian, Cameroonian, Ethiopian, and British.  Those with a higher frequency of B were Nigerien, American, Nepalese, and two nationalities with higher AB frequency Filipino and Chinese. 91.6 % of all populations were Rh-positive, and 8.4% were Rh-negative. The Saudi participants were like some nationalities and differed from others. Conclusion:  In Makkah city, the higher frequency of ABO blood group in Saudi and non -Saudi people is O followed by A, then B, and AB.  The Rh-positive is predominant, and 8.4% of the participants are negative. The ABO and Rh blood groups' identifications are essential for providing suitable blood storage for individuals in need.

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