scholarly journals Glutathione-S-transferase isoenzymes in Wilms' tumor and normal kidney tissue.

1993 ◽  
Vol 40 (1) ◽  
pp. 186-188 ◽  
Author(s):  
J Gajewska ◽  
M Szczypka ◽  
T Laskowska-Klita
Keyword(s):  
Wilms Tumor ◽  
Kidney Tissue ◽  
Normal Kidney ◽  
Glutathione S Transferase ◽  
Normal Kidney Tissue

Analysis of DNMT1 Gene Polymorphisms in Sporadic Wilms Tumor

2011 ◽  
Vol 393-395 ◽  
pp. 593-596
Author(s):  
Rui Bai ◽  
Xiao Li Hu ◽  
Lin Sheng Zhao ◽  
Xin Geng ◽  
Wei Ming Zhang
Keyword(s):  
Wilms Tumor ◽  
Kidney Tissue ◽  
Clinicopathological Parameters ◽  
Nucleotide Polymorphisms ◽  
Normal Kidney ◽  
Coding Region ◽  
Gene Frequencies ◽  
Normal Tissues ◽  
Normal Kidney Tissue ◽  
Pcr Products

To detect two single nucleotide polymorphisms (SNPs) in DNMT1 gene and the expression of corresponding region (1aa-120aa) in Wilms tumor (WT) and normal kidney tissue and analyze the association of polymorphism with clinicopathological parameters. Genomic DNA was extracted from tumor and normal tissues. PCR was used to amplify two SNP sites (rs16999593 and rs75616428 from the coding region of DNMT1). The PCR products were sequenced and genotyped. The protein expression of the first 120 aa of DNMT1 was evaluated by immunohistochemistry. Among 25 cases whose genotypes and gene frequencies studied, 18 cases of heterozygosity and 2 cases of homozygosity were identified. The region of the first 120 aa of DNMT1 was expressed in epithelial cells in normal kidney tissue, but was upregulated in tumors. The rs16999593 polymorphism might be used as a risk factor for WT diagnosis.

A Comparison Between Sterological Point Counting and Digitizing Tablets

1985 ◽  
Vol 43 ◽  
pp. 666-667
Author(s):  
John M. Basgen ◽  
Eileen N. Ellis ◽  
S. Michael Mauer ◽  
Michael W. Steffes
Keyword(s):  
Electron Microscopy ◽  
Kidney Tissue ◽  
Volume Density ◽  
Diabetic Patients ◽  
Normal Kidney ◽  
Point Counting ◽  
Normal Kidney Tissue ◽  
Biopsy Specimens ◽  
Mitochondrial Volume ◽  
Kidney Lesions

To determine the efficiency of methods of quantitation of the volume density of components within kidney biopsies, techniques involving a semi-automatic digitizing tablet and stereological point counting were compared.Volume density (Vv) is a parameter reflecting the volume of a component to the volume that contains the component, e.g., the fraction of cell volume that is made up of mitochondrial volume. The units of Vv are μm3 /μm3.Kidney biopsies from 15 patients were used. Five were donor biopsies performed at the time of kidney transplantation (patients 1-5, TABLE 1) and were considered normal kidney tissue. The remaining biopsies were obtained from diabetic patients with a spectrum of diabetic kidney lesions. The biopsy specimens were fixed and embedded according to routine electron microscogy protocols. Three glomeruli from each patient were selected randomly for electron microscopy. An average of 12 unbiased and systematic micrographs were obtained from each glomerulus and printed at a final magnification of x18,000.

Histology of Normal Kidney Tissue

1978 ◽  
pp. 21-45 ◽  
Author(s):  
Hans Ulrich Zollinger ◽  
Michael Jörg Mihatsch
Keyword(s):  
Kidney Tissue ◽  
Normal Kidney ◽  
Normal Kidney Tissue

Protein profiling of microdomains purified from renal cell carcinoma and normal kidney tissue samples

2012 ◽  
Vol 8 (4) ◽  
pp. 1007-1016 ◽  
Author(s):  
F. Raimondo ◽  
L. Morosi ◽  
C. Chinello ◽  
R. Perego ◽  
C. Bianchi ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Kidney Tissue ◽  
Protein Profiling ◽  
Normal Kidney ◽  
Tissue Samples ◽  
Normal Kidney Tissue

Trisomy 7, trisomy 10, and loss of the Y chromosome in short-term cultures of normal kidney tissue

1990 ◽  
Vol 53 (2-3) ◽  
pp. 123-125 ◽  
Author(s):  
P. Elfving ◽  
J.C. Cigudosa ◽  
R. Lundgren ◽  
J. Limon ◽  
N. Mandahl ◽  
...  
Keyword(s):  
Y Chromosome ◽  
Kidney Tissue ◽  
Normal Kidney ◽  
Short Term ◽  
Normal Kidney Tissue ◽  
Trisomy 7
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