scholarly journals Morphological Changes in Transplanted Sarcoma S45 at Photodynamic Therapy Using Nanocomposites Based on Gold Nanorods

2015 ◽  
Vol 15 (4) ◽  
pp. 22-27
Author(s):  
A.B. Bucharskaya ◽  
◽  
E.A. Genina ◽  
A.N. Bashkatov ◽  
G.S. Terentyuk ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Gold Nanorods ◽  
Morphological Changes

Gold nanorods as dual photo-sensitizing and imaging agents for two-photon photodynamic therapy

Nanoscale ◽  
2012 ◽  
Vol 4 (24) ◽  
pp. 7712 ◽  
Author(s):  
Tingting Zhao ◽  
Xiaoqin Shen ◽  
Lin Li ◽  
Zhenping Guan ◽  
Nengyue Gao ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Gold Nanorods ◽  
Imaging Agents ◽  
Two Photon

Gold Nanorods in Photodynamic Therapy, as Hyperthermia Agents, and in Near-Infrared Optical Imaging

2010 ◽  
Vol 122 (15) ◽  
pp. 2771-2775 ◽  
Author(s):  
Wen-Shuo Kuo ◽  
Chich-Neng Chang ◽  
Yi-Ting Chang ◽  
Meng-Heng Yang ◽  
Yi-Hsin Chien ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Optical Imaging ◽  
Gold Nanorods ◽  
Near Infrared

scholarly journals Evaluation of the dentin changes in teeth subjected to endodontic treatment and photodynamic therapy

2016 ◽  
Vol 45 (6) ◽  
pp. 339-343
Author(s):  
Mariane Floriano Lopes Santos LACERDA ◽  
Carolina Oliveira de LIMA ◽  
Gabriel Pinheiro LACERDA ◽  
Celso Neiva CAMPOS
Keyword(s):  
Photodynamic Therapy ◽  
Morphological Changes ◽  
Chi Square ◽  
Dentinal Tubules ◽  
Level Laser ◽  
Significant Difference ◽  
Root Dentin ◽  
Root Canal System ◽  
Student’S T ◽  
Apical Leakage

Abstract Introduction Antimicrobial photodynamic therapy (PDT) is an efficient adjuvant technique to promote disinfection of the root canal system. Therefore, it is important to investigate changes to dentin morphology and permeability induced by the use of diode laser on the root dentin. Objective The purpose of this study was to investigate morphological changes and the percentage of apical leakage after the use of laser. Material and method Forty single-rooted teeth were instrumented using rotary system and irrigated. Teeth were randomly divided in two groups: G1 - not exposed to PDT (control), and G2 - pretreated with toluidine blue photosensitizer and irradiated with AsGaAl laser diode. Ten teeth in each group were evaluated by SEM for morphological changes. The other ten teeth were filled and stained with Rhodamine B to evaluate the apical leakage. Result The results showed significant difference between G1 and G2 (p <0.001 - chi-square), with greater presence of debris in G1 and higher incidence of open dentinal tubules in G2. Erosions and cracks were observed in both groups, with no statistically significant difference (p> 0.001). The apical leakage was significantly higher in G2 than in G1 (p <0.001 - Student's t-test). Conclusion It was concluded that the use of low-level laser reduced the smear layer and opened the dentinal tubules. Use of laser increased the permeability of the apical dentin.

Highly effective photodynamic inactivation of E. coli using gold nanorods/SiO2 core–shell nanostructures with embedded verteporfin

2015 ◽  
Vol 51 (91) ◽  
pp. 16365-16368 ◽  
Author(s):  
Kostiantyn Turcheniuk ◽  
Volodymyr Turcheniuk ◽  
Charles-Henri Hage ◽  
Tetiana Dumych ◽  
Rostyslav Bilyy ◽  
...  
Keyword(s):  
Urinary Tract Infection ◽  
Photodynamic Therapy ◽  
Gold Nanorods ◽  
Virulent Strain ◽  
Silica Shell ◽  
Core Shell ◽  
Photodynamic Inactivation ◽  
E Coli ◽  
Shell Nanostructures ◽  
20 Nm

The potential of gold nanorods coated with a 20 nm silica shell loaded with verteporfin as efficient NIR nanostructures for photodynamic therapy to eradicate a virulent strain of E. coli associated with urinary tract infection is described.

scholarly journals Morphological Changes in the Internal Organs and Implanted Liver Tumor after Intravenous Injection of Gold Nanorods in Rats with Diabetes and Transplanted Tumor

2012 ◽  
Vol 12 (2) ◽  
pp. 31-37
Author(s):  
Alla Borisovna Bucharskaya ◽  
◽  
Georgiy Sergeevich Terentyuk ◽  
Galina Nikiphorovna Maslyakova ◽  
Olga Viktorovna Matveeva ◽  
...  
Keyword(s):  
Intravenous Injection ◽  
Gold Nanorods ◽  
Liver Tumor ◽  
Morphological Changes ◽  
Internal Organs ◽  
Transplanted Tumor

scholarly journals The Cellular Uptake of Sensitizers Bound to Cyclodextrin Carriers

2004 ◽  
Vol 47 (4) ◽  
pp. 313-315 ◽  
Author(s):  
Hana Kolářová ◽  
Martin Huf ◽  
Jaroslav Maceček ◽  
Pavla Nevřelová ◽  
Marek Tomečka ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Cellular Uptake ◽  
Morphological Changes ◽  
Time Interval ◽  
Fluorescent Microscope ◽  
Photodynamic Therapy Of Cancer ◽  
Plate Reader ◽  
Hydroxypropyl Cyclodextrins ◽  
The Given

Photodynamic therapy of cancer uses the interaction of sensitizers and light to destroy cancer cells. In this study we tested the cellular uptake of meso-tetrakis(4-sulfonatophenyl)porphine (TPPS4) and its complex PdTPPS4 in the presence or absence of 2–hydroxypropyl-cyclodextrins (hpCDs) on G361 human melanoma cells. Self-fluorescence in G361 cells were measured by Perkin-Elmer LS50B luminometer equipped with well plate reader accessory. Morphological changes in cells have been evaluated using inversion fluorescent microscope Olympus IX 70 and image analysis. The uptake of the sensitizer PdTPPS4 at the given time interval from 1 to 48 hours is markedly higher than the uptake of TPPS4. The highest uptake was found for sensitizer PdTPPS4 in combination with hpβCD. TPPS4 and PdTPPS4 especially in the supramolecular complex with nontoxic cyclodextrin carriers represent efficient sensitizers for photodynamic therapy in vitro on G361 cells.

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