The Effect of Green Coffee Consumption on High Blood Pressure

2021 ◽  
Author(s):  
Mahdieh Hosseinzadeh ◽  
Fatemeh Pakravanfar ◽  
Elham Hosseinzadeh ◽  
Maryam Khosravi
Keyword(s):  
Blood Pressure ◽  
Clinical Trials ◽  
High Blood Pressure ◽  
Coffee Consumption ◽  
Vascular Diseases ◽  
Publication Date ◽  
Green Coffee ◽  
Chlorogenic Acids ◽  
Coffee Intake ◽  
Randomized Controlled Clinical Trials

Background: Hypertension is a major risk factor for the development of coronary, cerebrovascular, and peripheral vascular diseases, which lead to myocardial infarction, stroke, and vascular death. Green coffee extract is particularly producer a great deal of chlorogenic acids (CGA) that may reduce the risk of high blood pressure. Therefore, the target of the study was to summarize the available publications on the effect of green coffee consumption on high blood pressure. Methods: The systematic review was done with a search in PubMed-Medline and Scopus. The search strategy included keywords related to blood pressure and green coffee. Inclusion criteria were randomized controlled clinical trials conducted on people aged between 18 and 70 years. The publication date of articles  was from 2004 to 2018. Exclusion criteria were articles not published in English. Results: We discussed five articles that included  our criteria. Green coffee had moderate effects on high blood pressure.  It sounds that the effect of green coffee on reducing blood pressure is because of its phenolic compounds, as well as caffeine and chlorogenic acids, coffee’s roasting status, participants’ ethnicity, and even gender. Conclusion: Green coffee intake for a long time might moderately decrease blood pressure. However, there is still a need for further clinical trials.

Coffee Consumption and Serum Lipids: A Meta-Analysis of Randomized Controlled Clinical Trials

2001 ◽  
Vol 153 (4) ◽  
pp. 353-362 ◽  
Author(s):  
Sun Ha Jee ◽  
Jiang He ◽  
Lawrence J. Appel ◽  
Paul K. Whelton ◽  
II Suh ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Serum Lipids ◽  
Meta Analysis ◽  
Coffee Consumption ◽  
Controlled Clinical Trials ◽  
Randomized Controlled Clinical Trials ◽  
Randomized Controlled

Effects of cinnamon supplementation on systolic and diastolic blood pressure: a systematic review and meta-analysis of randomized controlled clinical trials

2021 ◽  
Author(s):  
Zeinab Yazdanpanah ◽  
Mandana Amiri ◽  
Azadeh Nadjarzadeh ◽  
Hadis Hooshmandi ◽  
Maryam Azadi-Yazdi
Keyword(s):  
Systematic Review ◽  
Blood Pressure ◽  
Clinical Trials ◽  
Diastolic Blood Pressure ◽  
Weighted Mean Difference ◽  
Meta Analysis ◽  
Cochrane Collaboration ◽  
Controlled Clinical Trials ◽  
Randomized Controlled Clinical Trials ◽  
Randomized Controlled

Introduction: Hypertension is a chronic condition that might lead to renal and cardiovascular diseases. The previous trials examining the effect of cinnamon supplementation on blood pressure have led to conflicting results. The present systematic review aimed to summarize the effect of cinnamon supplementation on blood pressure using a meta-analysis of published randomized controlled clinical trials. Methods: To identify the eligible articles, MEDLINE, SCOPUS, ISI Web of Science, and Google Scholar were searched from inception until September 2019 for relevant articles. The risk of bias assessment was performed using the Cochrane collaboration tool. A Random-effects model was applied to calculate the summary effects. Results: Totally, 11 trials with 686 participants were included in this systematic review and meta-analysis. The dose of cinnamon supplement consumption varied from 500 to 10000 mg/d. The meta-analysis revealed that cinnamon supplementation significantly decreases systolic blood pressure (SBP) [WMD (weighted mean difference)= -5.72 mmHg, 95% confidence interval (CI): -8.63 to -2.80; P<0.001, I2= 81.1)] and diastolic blood pressure (DBP) (WMD= -4.06 mmHg, 95% CI: -6.68 to -1.44; P= 0.002, I2 = 88.6). Subgroup analysis suggested no significant reduction of DBP in subjects with diabetes (WMD= -2.015 mmHg, 95% CI: -4.55 to 0.52; P= 0.12, I2 = 72.3) and prediabetes or metabolic syndrome (WMD= -4.8 mmHg, 95% CI: -10.06 to 0.44; P= 0.073, I2= 92.5). Conclusions: Cinnamon supplementation could be beneficial in lowering SBP and DBP in adults. Further studies with different doses are recommended to confirm the present findings.

Effects of orlistat on blood pressure: a systematic review and meta-analysis of 27 randomized controlled clinical trials

2018 ◽  
Vol 12 (2) ◽  
pp. 80-96 ◽  
Author(s):  
Amirhossein Sahebkar ◽  
Luis E. Simental-Mendía ◽  
Petri T. Kovanen ◽  
Claudio Pedone ◽  
Mario Simental-Mendía ◽  
...  
Keyword(s):  
Systematic Review ◽  
Blood Pressure ◽  
Clinical Trials ◽  
Meta Analysis ◽  
Controlled Clinical Trials ◽  
Randomized Controlled Clinical Trials ◽  
Randomized Controlled

scholarly journals Healthy Living for Elders: High Blood Pressure

EDIS ◽  
1969 ◽  
Vol 2004 (11) ◽  
Author(s):  
Leigh Ann Martin
Keyword(s):  
Blood Pressure ◽  
Blood Vessels ◽  
High Blood Pressure ◽  
Cooperative Extension ◽  
Cooperative Extension Service ◽  
Extension Service ◽  
Publication Date ◽  
Healthy Living ◽  
University Of Florida ◽  
Increased Pressure

High blood pressure is increased pressure of blood on the blood vessels. This creates more work for the heart. Another name for high blood pressure is hypertension. About 50 million Americans may have hypertension. Many are not even aware they have a problem. This document, FCS8599-Eng, is one in a series of the Department of Family, Youth and Community Sciences, Florida Cooperative Extension Service, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, FL 32611. Publication date: March 2004.  https://edis.ifas.ufl.edu/fy684

scholarly journals Prevalence of Blood Pressure among Green Coffee Users of Young and Middle Age Saudis

2020 ◽  
Vol 8 (4S5) ◽  
pp. 92-100
Keyword(s):  
Blood Pressure ◽  
Coffee Consumption ◽  
Signs And Symptoms ◽  
Consumption Patterns ◽  
Prognosis Factors ◽  
Coffee Intake ◽  
Arabica Coffee ◽  
Site Water ◽  
History Of ◽  
Self Administered Questionnaire

This is an analytical descriptive cross-section study. It was conducted among youth Saudis coffee consumers. It aimed at detecting the coffee consumption patterns (coffee type, concentration, volume/day, time length, site, water drink after coffee intake) concerning the onset of high BP, and signs and symptoms suggesting its presence. The hypothesis is the presence of significant inter-relation between them.Non-probability convenient sampling was applied; a self-administered questionnaire was developed, tested and filled by 340 males and females students, their relatives, besides the Faculty of Public and Tropical Medicine administrative staff. Findings showed that a total of 50 (14.7%) respondents reported having high BP. Of them, 29 (58%) were users of Arabica coffee (only), while 49 (98%) used the Arabica coffee along with other coffee types. The OR showed that the consumers of Arabica coffee (only) were at 1.79 risks of contracting high BP, while the favorites of each of the concentrated, and the homemade coffee were at 1.5 and 2.1 risks respectively. The homemade predictor value was significantly (P<0.05) related to high BP. Apart from the intake of Arabica coffee (only), the OR of all coffee consumption patterns were seen to be prognosis factors of contracting 4+signs and symptoms suggesting high blood pressure. But, no significant (P>0.05) relation was there. Familial history of high BP, and below university OR were at 1.7 and 1.9 risks of contracting high BP respectively. However, no significant (P>0.05) relation was there.The conclusion is that the consumers of Arabica coffee (only) were almost 2 times the risk of contracting high BP. Each of the homemade and strong coffee was seen to be prognosis factors of both contracting high BP and of having 4+ signs and symptoms suggesting its presence.

scholarly journals The Effect of Coffee Consumption Behavior on Increased Blood Pressure

2021 ◽  
Vol 2 (2) ◽  
pp. 1-8
Author(s):  
Karina Kaptelova ◽  
Elena Pysanka
Keyword(s):  
Blood Pressure ◽  
High Blood Pressure ◽  
Coffee Consumption ◽  
Adverse Impact ◽  
Healthy Individuals ◽  
Chi Square ◽  
Cross Sectional ◽  
Consumption Behavior ◽  
Chi Square Test

The purpose of this research is to establish whether or not coffee has an adverse impact on blood pressure. Analytic observation was used in this kind of study, which was carried out utilizing a cross-sectional methodology and analytic observation. The findings were similar with individuals who had never experienced hypertension. Also, the proportion of healthy individuals was greater. A research shows that coffee consumption raises blood pressure. The research comprised 42 people who drank coffee three times or more per day and had high blood pressure (80.7 of the time) The chi-square test revealed that coffee consumption raises blood pressure by p = 0.000

Abstract 025: AMP-activated Protein Kinase Mediates Pressure Overload-induced Hypertrophy

Hypertension ◽  
2016 ◽  
Vol 68 (suppl_1) ◽  
Author(s):  
Jinli Wang ◽  
Nanhu Quan ◽  
Lin Wang ◽  
Courtney Cates ◽  
Ji Li
Keyword(s):  
Blood Pressure ◽  
Protein Kinase ◽  
High Blood Pressure ◽  
Morphological Changes ◽  
Heart Function ◽  
Pressure Overload ◽  
Vascular Diseases ◽  
Adenosine Monophosphate ◽  
Macrophage Infiltration ◽  
Therapeutic Drug

Hypertension is a major risk factor of death and disability from heart and vascular diseases. Heart hypertrophy caused by pressure overload is characterized by the activation of adenosine monophosphate-activated protein kinase (AMPK), which is the major energy sensor in the heart. However, the anti-inflammatory effect of AMPK has not been investigated in the hypertrophy model. Activated protein C (APC) is a vitamin-K dependent plasma serine protease which inhibits blood clotting, and APC is an endogenous AMPK agonist. This study was designed to examine the role of AMPK in hypertrophy and the underlying mechanisms by which APC inhibits heart hypotrophy by pressure overload. We hypothesize that AMPK play a role in preventing heart from hypertrophy induced by pressure overload. APC could inhibit high blood pressure-induced hypertrophy via activation of AMPK signaling pathway. Wild-type (WT) and AMPK-kinase dead (KD) transgenic mice were subjected to transverse aortic constriction (TAC) surgery. Echocardiography was performed to evaluate the heart function, and histology staining revealed the morphological changes. Real-time PCR and western blotting were used to detect the signaling changes of both mRNA and protein expression levels. There is no phenotype difference between WT and AMPK-KD mice under normal physiological conditions. However after 4 weeks of TAC surgery, AMPK-KD mice demonstrated significantly bigger heart than WT mice (p<0.05), and the cardiac functions measured by echocardiography in AMPK-KD hearts were significantly impaired as compared with WT hearts (p<0.05). The immunohistochemical staining showed that the increased macrophage infiltration and reactive oxygen species (ROS) including activated p66shc, 4-HNE and ERK were observed in the AMPK-KD hearts after 4 weeks of TAC surgery (all p<0.05 versus WT hearts). APC administration significantly attenuated hypertrophy and fibrosis caused by pressure overload, and macrophage infiltration and p66shc activation were also inhibited by APC treatment. Therefore, Cardiac AMPK deficiency aggravates hypertrophy caused by pressure overload. AMPK activator APC could be a therapeutic drug for treatment of hypertrophy by high blood pressure.

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