scholarly journals Oropharyngeal candidiasis in HIV/AIDS patients and HIVfree subjects in the Southeast of Iran

2019 ◽  
Author(s):  
Abbas Hosain Pour ◽  
Samira Salari ◽  
Pooya Ghasemi Nejad Almani
Keyword(s):  
Hiv Infection ◽  
Candida Species ◽  
Age Group ◽  
Oropharyngeal Candidiasis ◽  
Aids Patients ◽  
Immunodeficiency Virus ◽  
Initial Sign ◽  
Effective Drugs ◽  
Isolated Species ◽  
Hiv Aids

Background and Purpose: Candida species are the common opportunistic pathogens during the course of human immunodeficiency virus (HIV) infection. Oropharyngeal candidiasis (OPC) is generally known as the initial sign of HIV infection. The aim of this study was to compare demographic characteristics and frequency of Candida species between HIV/AIDS patients and HIV-free subjects in Kerman, southeast of Iran. Materials and Methods: This study was conducted on 143 samples collected from the oral cavity of 81 HIV/AIDS patients and 35 HIV-free subjects. The samples were cultured on Sabouraud dextrose agar and CHROMagar. The identification of Candida species was accomplished using the color of colony and polymerase chain reactionrestriction fragment length polymorphism. Results: According to the results, C. albicans (n=25, 69.14%) was the most prevalent species isolated from the HIV/AIDS patients, followed by C. glabrata (n=19, 23.46%). Other isolated species included C. parapsilosis (n=4, 4.94 %), C. krusei (n=1, 1.24%), and C. kefyr (n=1, 1.24%). Out of the 35 Candida species recovered from the oral samples of HIV-free subjects, 23 (65.71%) and 12 (34.29%) cases were C. krusei and C. albicans, respectively. Candida krusei was the only non-albicans species found in the HIV-free subjects that was also the predominant isolated species. Regarding the HIV/AIDS patients, the highest prevalence of OPC was observed in the age group of 4150 years. However, in the HIV-free subjects, the age group of 31-40 years had the highest prevalence of this infection. Furthermore, no correlation was observed between the gender and number of Candida isolates. Conclusion: Consideration of the epidemiologic data showed that the two groups were significantly different in terms of the prevalence of Candida species, which could play a major role in the selection of effective drugs for the treatment of candidiasis

Iranian HIV/AIDS patients with oropharyngeal candidiasis: identification, prevalence and antifungal susceptibility of Candida species

2018 ◽  
Vol 67 (4) ◽  
pp. 392-399 ◽  
Author(s):  
S. Khedri ◽  
A.L.S. Santos ◽  
M. Roudbary ◽  
R. Hadighi ◽  
M. Falahati ◽  
...  
Keyword(s):  
Candida Species ◽  
Antifungal Susceptibility ◽  
Oropharyngeal Candidiasis ◽  
Aids Patients ◽  
Hiv Aids

Randomized Trial of Itraconazole Oral Solution for Oropharyngeal Candidiasis in HIV/AIDS Patients

1998 ◽  
Vol 104 (1) ◽  
pp. 33-39 ◽  
Author(s):  
John R. Graybill ◽  
Jose Vazquez ◽  
Rabih O. Darouiche ◽  
Robert Morhart ◽  
Deborah Greenspan ◽  
...  
Keyword(s):  
Randomized Trial ◽  
Oral Solution ◽  
Oropharyngeal Candidiasis ◽  
Aids Patients ◽  
Hiv Aids

scholarly journals Co-infection by Cryptococcus neoformans fungaemia and Non tuberculous Mycobacterium together with Pneumocystis jiroveci pneumonia in a patient with newly diagnosed HIV infection

2021 ◽  
Author(s):  
Eihab Subahi ◽  
safwan aljafar ◽  
haidar barjas ◽  
Mohamed Abdelrazek ◽  
Fatima Rasoul
Keyword(s):  
Human Immunodeficiency Virus ◽  
Hiv Infection ◽  
Cryptococcus Neoformans ◽  
Opportunistic Infections ◽  
Newly Diagnosed ◽  
Aids Patients ◽  
Pneumocystis Jiroveci ◽  
Pneumocystis Jiroveci Pneumonia ◽  
Immunodeficiency Virus

Opportunistic infections are common in human immunodeficiency virus (HIV)-infected patients. Co-infections with Cryptococcus neoformans together with Mycobacterium and Pneumocystis jiroveci pneumonia (PCP) are rare, and typically occur in immunocompromised individuals, particularly AIDS patients.

scholarly journals KORELASI ANTARA HITUNG TROMBOSIT DENGAN JUMLAH CD4 PASIEN HIV/AIDS

2018 ◽  
Vol 17 (2) ◽  
pp. 102
Author(s):  
M. I. Diah Pramudianti ◽  
Tahono Tahono
Keyword(s):  
Immune Deficiency Syndrome ◽  
Deficiency Syndrome ◽  
Common Finding ◽  
Aids Patients ◽  
Cross Sectional ◽  
Thrombocyte Count ◽  
Immunodeficiency Virus ◽  
Cross Sectional Design ◽  
Acquired Immune Deficiency ◽  
Hiv Aids

The Acquired Immune Deficiency Syndrome (AIDS) is the presence of symptoms caused by Human Immunodeficiency Virus (HIV)which belongs to human retroviruses (retroviridae). Thrombocytopenia is a common finding in patients with HIV infection. HIV infectionmay induce thrombocytopenia through immune and non-immune mechanisms, autoimmune combination and inhibition of plateletproduction. The aim of this study is to analyze the correlation between thrombocyte and CD4 count in HIV/AIDS patients. This studyuses a cross sectional design with a total of 17 patients. The subject of this study is HIV/AIDS patients who came to and examined atVCT clinic, dr. Moewardi Hospital Surakarta. To analyze this result the researchers used Spearman (r) correlation with p<0.05, andconfidence interval 95%. Patients’ median age was 30 (21–49) years, 11 (64.7%) men and 6 (35.3%) women. The subjects with AIDSwere 11 (64.7%), and HIV were 6 (35.3%) patients. The duration of antiretroviral (ARV) was 7.5 (4–20) months in 10 subjects.The median of thrombocyte count was 203 (143–327)×103/μL, CD4 absolute 207 (5.0–734)/μL, and CD4 (% lymphocytes) 13.0(2.0–29.0)%. The thrombocyte count was not correlated with CD4 absolute (r=0.456; p=0.066) and CD4% (r=0.218; p=0.400). InHIV patients, low platelet counts will be the result of a host of problems and complications that are associated with the progressive HIVinfection or its management.

scholarly journals Sonographic detection of abdominal pathologies in human immunodeficiency virus/acquired immunodeficiency syndrome patients and its correlation with CD4 counts – A prospective analysis

2020 ◽  
Vol 0 ◽  
pp. 1-8
Author(s):  
Tejas Kanthrao Mankeshwar ◽  
Ashok Kumar Sharma
Keyword(s):  
Human Immunodeficiency Virus ◽  
Lymph Nodes ◽  
Acquired Immunodeficiency Syndrome ◽  
Cd4 Count ◽  
Aids Patients ◽  
Cd4 Counts ◽  
Immunodeficiency Virus ◽  
Acquired Immunodeficiency ◽  
Immunodeficiency Syndrome ◽  
Hiv Aids

Objectives: Abdominal pathologies are the second most common after pulmonary diseases in human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) patients. Ultrasonography (USG) is a vital imaging technique for the evaluation of abdominal pathologies. This study was aimed at evaluating the abdominal pathologies using USG in HIV/AIDS and further analysis of its correlation with CD4 count. Material and Methods: The present study was carried out on 392 HIV-positive patients with abnormal abdominal sonographic findings. All data were analyzed by Chi-square test and one-way analysis of variance using SPSS 16.0 software. Results: Of these 392 patients, 66.3% were males, the mean age was 35.7 years, (range 7–64 years) and most of them were in 4th decade. On ultrasonographic evaluation, spleen was involved in 45.2% patients and liver as well as lymph nodes each was involved in 43.6% patients. Other cases displayed ascites and bowel thickening in 5.3% and 3.8% patients, respectively. Less involvement of kidney (2.3%), pancreas (1.5%), and biliary system (1.3%) was observed. In addition, pathologies such as hepatomegaly, splenomegaly, splenic microabscess, focal pancreatic lesion, mesenteric, and periportal lymphadenopathy showed significant correlation with CD4 counts. Lymphoma was found in 1% of patients, involving liver, pancreas, and retroperitoneal lymph nodes. Conclusion: Our study highlights the clinical utility of abdominal USG in HIV/AIDS patients. CD4 counts largely affect the differential diagnosis in HIV/AIDS patients. USG findings interpreted in the context of CD4 count may help in guiding the exact diagnosis.

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