scholarly journals Aspiration versus retention ultrasound-guided ethanol sclerotherapy for treating endometrioma: A retrospective cross-sectional study

2020 ◽  
Author(s):  
Abbas Aflatoonian ◽  
Nasim Tabibnejad
Keyword(s):  
Recurrence Rate ◽  
Transvaginal Ultrasound ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Ethanol Injection ◽  
Vitro Fertilization ◽  
Ethanol Sclerotherapy ◽  
Retention Group ◽  
Improve Pregnancy Outcome

Background: Endometrioma is a common high-recurrence gynecological disease that affects infertility. Surgical resection using laparotomy or laparoscopy is applied as a standard treatment. Moreover, sclerotherapy is reported to be effective as a noninvasive method for treating endometrioma. Objective: To evaluate whether the ethanol retention or aspiration after sclerotherapy improve pregnancy outcome in infertile women with endometrioma. Materials and Methods: In a retrospective study, hospital records of 43 women with recurrent or bilateral endometrioma who had been undergone transvaginal ultrasound sclerotherapy were reviewed. They were selected to receive either ethanol for 10 min, ethanol injection, irrigation, and then aspiration or total retention without aspiration based on the surgeon’s decision. The participants were followed-up for 3, 6 and 12 months for natural or artificial conception as well as for cyst recurrence. Results: Chemical pregnancy was positive in 52% of the women in the aspiration group and 53.8% in the retention group. Ongoing pregnancy (44% vs 46.2%, p = 0.584) and live birth (40% vs 46.2%, p = 0.490) were reported marginally higher in the retention group compared with the aspiration group, and the differences were not statistically significant. Moreover, the recurrence rate were found to be 48.1% and 37.5% in the aspiration and retention groups, respectively (p = 0.542). The cysts size in the retention group was significantly correlated to the recurrence rate. Conclusion: Both the aspiration and left in situ of ethanol 95% sclerotherapy have the similar impact on the treatment of ovarian endometrioma regarding pregnancy and recurrence rate. However, larger randomized studies with strict inclusion criteria are needed. Key words: Endometrioma, Ethanol, Sclerotherapy, In vitro fertilization, Pregnancy rate.

scholarly journals Transferrin and antioxidants partly prevented mouse oocyte oxidative damage induced by exposure of cumulus-oocyte complexes to endometrioma fluid

2020 ◽  
Vol 13 (1) ◽  
Author(s):  
Zi Ren ◽  
Jiana Huang ◽  
Chuanchuan Zhou ◽  
Lei Jia ◽  
Manchao Li ◽  
...  
Keyword(s):  
Oxidative Damage ◽  
Oocyte Retrieval ◽  
Cross Sectional Study ◽  
Human Oocyte ◽  
Cross Sectional ◽  
Vitro Fertilization ◽  
Good Quality Embryo ◽  
Damage Process ◽  
Human And Mouse

Abstract Background Exposure of oocytes to the endometrioma fluid has an adverse effect on embryonic quality. To determine whether adding transferrin and antioxidants to culture medium could counteract detrimental effects on mouse cumulus-oocyte complexes (COCs) induced by exposure to endometrioma fluid or not, we conducted an in vitro cross-sectional study using human and mouse COCs. Methods Eighteen women who had their oocytes exposed to endometrioma fluid during oocyte retrieval were enrolled. COCs from superovulated ICR female mice were collected. They were first exposed to human endometrioma fluid and then treated by transferrin and/or antioxidants (cysteamine + cystine). Subsequently, COCs function was assessed by molecular methods. Results This study observed that human COCs inadvertently exposed to endometrioma fluid in the in vitro fertilization (IVF) group led to a lower good quality embryo rate compared to intracytoplasmic sperm injection (ICSI) group. Exposure of mouse COCs to endometrioma fluid accelerated oocyte oxidative damage, evidenced by significantly reduced CCs viability, defective mitochondrial function, decreased GSH content and increased ROS level, associated with the significantly higher pro-portion of abnormal spindles and lower blastocyst formation (p < 0.05, respectively). This damage could be recovered partly by treating COCs with transferrin and antioxidants (cysteamine + cystine). Conclusions Transferrin and antioxidants could reduce the oxidative damage caused by COCs exposure to endometrioma fluid. This finding provides a promising new possibility for intervention in the human oocyte oxidative damage process induced by endometrioma fluid during oocyte pick-up.

Factors that influence in vitro fertilization treatment outcomes of Chinese men: A cross-sectional study

2016 ◽  
Vol 32 ◽  
pp. 222-226 ◽  
Author(s):  
Dan Chen ◽  
Jing Ping Zhang ◽  
Ling Jiang ◽  
Huayan Liu ◽  
Ling Shu ◽  
...  
Keyword(s):  
In Vitro Fertilization ◽  
Treatment Outcomes ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Vitro Fertilization ◽  
Chinese Men

scholarly journals A Two-year Cross-sectional Prospective Study for Assessment of Endometrial Thickness and Volume using Three-dimensional Transvaginal Ultrasound among in vitro Fertilization Patients of Royan Institute in Iran

2016 ◽  
Vol 10 (4) ◽  
pp. 398-402
Author(s):  
Firoozeh Ahmadi ◽  
Farnaz Akhbari ◽  
SH Irani ◽  
M Shiva ◽  
A Maghari
Keyword(s):  
In Vitro Fertilization ◽  
Prospective Study ◽  
Endometrial Thickness ◽  
Transvaginal Ultrasound ◽  
Three Dimensional ◽  
Controlled Ovarian Hyperstimulation ◽  
Cross Sectional ◽  
Vitro Fertilization ◽  
Group I

ABSTRACT Introduction To evaluate the role of endometrial thickness and volume using three-dimensional transvaginal ultrasound (3-D TVUS) in order to predict pregnancy outcome in assisted reproductive technology (ART) cycle on the day of human chorionic gonadotropin (hCG) administration. Materials and methods In this prospective study, the long protocol of controlled ovarian hyperstimulation was prescribed for women. Endometrial thickness and volume were measured using the 3-D TVUS, for 166 women undergoing ART cycle, on the day of hCG administration at Royan Institute, Tehran, Iran, between 2009 and 2011. All patients were divided into three groups. Regarding endometrial thickness, there are three groups as follows: Group I: . 7 mm, group II: 7.14 mm, and group III: > 14 mm; all patients were also divided into three groups according to endometrial volume calculated as follows: Group IV: < 2 cc, group V: 2.4.5 cc, group VI: > 4.5 cc. Pregnancy rate (PR) was compared between all groups. Results A total of 166 patients were analyzed. Overall PR was 39.8% after in vitro fertilization (IVF). Participant's age ranged from 20 to 38 years old with the mean age of 29.9 ± 4.23. No significant cut-off value was found for endometrial thickness and volume. Conclusion Endometrial thickness and volume on the day of hCG are significant in limited value and in a clinical setting for predicting implantation in ART cycle. How to cite this article Ahmadi F, Akhbari F, Irani SH, Shiva M, Maghari A. A Two-year Cross-sectional Prospective Study for Assessment of Endometrial Thickness and Volume using Threedimensional Transvaginal Ultrasound among in vitro Fertilization Patients of Royan Institute in Iran. Donald School J Ultrasound Obstet Gynecol 2016;10(4):398-402.

scholarly journals Factors Related to the Number of Antral Follicles on InVitro Fertilization (IVF)

2016 ◽  
pp. 75
Author(s):  
Fransiskus C Raharja ◽  
Ketut Suwiyoga ◽  
IPG Wardhiana
Keyword(s):  
Prevalence Ratio ◽  
Cross Sectional Study ◽  
Chi Square ◽  
Cross Sectional ◽  
Vitro Fertilization ◽  
Antral Follicles ◽  
Chi Square Test ◽  
The Mean ◽  
Infertile Patients

Objective: To determine factors which are related to the number of antral follicles on infertile patients. Method: This cross sectional study was conducted in In-Vitro Fertilization (IVF) clinic of Graha Tunjung, Sanglah hospital, Bali. All fertile patients following the IVF program were calculated the number of antral follicles in both ovarian using transgene USG. This sample was recruited by random sampling from April 1st, 2001 to April 30th, 2011. We analyzed the data using Chi square test through SPSS for Windows 17.0 version. Result: Of 102 samples, the mean of patients’ age was 32.9% (SD 4.6) years old. From 72 patients (70.6%) experienced above 3 years of infertile period, the primary infertile was on 69 patients (67.7%). There was a relationship between patients’ age and the number of antral follicles significantly (prevalence ratio (PR) 1.41; 95% CI 1.11- 1.79). Meanwhile, the number of antral follicles and type of infertile (PR 1.02; 95% CI 0.76-1.37) also infertile period (PR 0.95; 95% CI 0.72-1.27) were not associated significantly. Conclusion: Patients’ age has an association with the number of antral follicles on IVF. [Indones J Obstet Gynecol 2016; 4-2: 75-77] Keywords: age, infertile, infertile period, number of antral follicles and type of infertile

scholarly journals Basal follicle stimulating hormone and leptin on the day of hCG administration predict successful fertilization in in vitro fertilization

2016 ◽  
Vol 25 (1) ◽  
pp. 39-43 ◽  
Author(s):  
Andon Hestiantoro ◽  
Budi Wiweko ◽  
Robert H. Purwaka
Keyword(s):  
In Vitro Fertilization ◽  
Follicle Stimulating Hormone ◽  
Oocyte Retrieval ◽  
Cross Sectional Study ◽  
Mature Oocyte ◽  
Cross Sectional ◽  
Vitro Fertilization ◽  
Fertility Clinic ◽  
Stimulating Hormone

Background: Successful pregnancy in in vitro fertilization (IVF) program depends on multiple factors. This study aimed to determine whether age, body mass index (BMI), basal follicle stimulating hormone (FSH), estradiol, and leptin on the day of trigger ovulation with human chorionic gonadotropin (hCG) might be used as predictor for successful oocyte fertilization in in vitro fertilization (IVF) program.Methods: This is a cross sectional study conducted in Yasmin Fertility Clinic, Cipto Mangunkusumo Hospital, Jakarta, Indonesia. Forty participating patients underwent IVF program, excluding smokers, patients with diabetic, morbid obesity, and severe oligospermia or azoospermia. Age, BMI, basal FSH, estradiol, leptin on the day of hCG administration, oocyte count on oocyte retrieval, the number of mature oocyte, and fertility rate were analyzed using bivariate and multivariate analysis to determine which eligible factors play role in predicting the successful of fertilization.Results: Significant correlation was found between basal FSH level and serum leptin/oocyte ratio on the day of hCG administration with successful fertilization. We found probability formula as follows: 1/(1+exp –(6.2 - 0.4(leptin serum/oocyte ratio) - 0.8(basal FSH)), with 77.8% sensitivity, 77.8% specificity, and AUC levels of 85.6% indicating strong predictability. Probability of successful fertilization related to basal FSH level of 5.90 mIU/mL and leptin serum/oocyte ratio of 3.98.Conclusion: The formula consisting of basal FSH and leptin serum/oocyte ratio on the day of trigger ovulation was capable in predicting the probability of successful fertilization in IVF procedure.

scholarly journals Evaluation of uterine cavity by hysteroscopic examination in infertile women in BSMMU

2016 ◽  
Vol 9 (1) ◽  
pp. 32 ◽  
Author(s):  
Jesmine Banu ◽  
Farzana Deeba ◽  
Parveen Fatima ◽  
Parveen Sultana
Keyword(s):  
Standard Procedure ◽  
Uterine Cavity ◽  
Cross Sectional Study ◽  
Infertile Woman ◽  
Cross Sectional ◽  
Vitro Fertilization ◽  
Infertile Women ◽  
Primary Infertility ◽  
Diagnostic Hysteroscopy

<p><strong>Background:</strong> Hysteroscopy is the gold standard procedure for uterine cavity exploration. However, hysteroscopy is only recommended by the WHO when clinical or complementary exams (ultrasound, HSG) suggest intrauterine abnormality or after in vitro fertilization failure. Nevertheless, many specialists feel that hysteroscopy is a more accurate tool.</p><p><strong>Objec­tive:</strong> The aim of this prospective study is to find out the evaluation of uterine cavity by hysteroscopic examination as a primary workup of infertility. To asses the uterine pathology which is the causal factor for infertility.</p><p><strong>Method:</strong> This is a cross sectional study in which total 100 infertile patients were enrolled from infertility OPD in BSMMU with maintain­ing inclusion and exclusion criteria Hysteroscopy was performed with a standard sequence. The endocervical canal, uterine cavity, endometrium, and tubal ostia were inspected and findings were recorded. Results: Hysteroscopy was performed in 100 infertile women,among them 44% were presented with primary infertility and 56% presented with secondary infertility. The most common indication for diagnostic hysteroscopy was as a part of an infertility workup 80% cases. Other indication included abnormal hysterosalphingography, recurrent pregnancy loss and unexplained infertility. Hysteroscopy revealed a normal uterine cavity in 51 ( 51 % ) women (Table 2).among them majority of patients were primary infertility.and age less than 30 years. Hysteroscopic abnormalities are significantly high in secondary than primary infertility.</p><p><strong>Conclusion:</strong> In this study abnormal hysteroscopic findings were found in 49% who underwent diagnostic hysteroscopy. Our data are an additional argument to suggest that diagnostic hysteroscopy as part of investiga­tion in infertile woman to evaluate uterine pathology. Routine diagnostic hysteroscopy should be part of an infertility workup in both primary and secondary infertility.At the same setting therapeutic approach also be possible which is beneficial for the patients.</p>

scholarly journals Precision follicular self-measurement using a pocket-sized transabdominal ultrasound device

2020 ◽  
Author(s):  
Hiroaki Fujita ◽  
Iwaho Kikuchi ◽  
Satoshi Enomoto ◽  
Ryo Nakagawa ◽  
Reiko Kitayama ◽  
...  
Keyword(s):  
Transvaginal Ultrasound ◽  
Transabdominal Ultrasound ◽  
Clinical Trial Registration ◽  
Cross Sectional ◽  
Vitro Fertilization ◽  
Mean Values ◽  
Follicle Diameter ◽  
Variance Ratios ◽  
The Difference

Abstract Background: The purpose of this study was to determine the comparability of follicle diameters measured using a pocket-size transabdominal ultrasound (TAUS) device that produces images for self-assessment versus those measured using a conventional transvaginal ultrasound (TVUS) device. The pocket-sized device is fitted with a probe that can be connected to an electronic tablet for patient use and outputs follicle images for patient review.Methods: A prospective study was performed in 25 women (50 follicles) who underwent in vitro fertilization (IVF)/intracytoplasmic sperm injection between November 2019 and March 2020 to treat infertility. Patients were first provided with guidance from a doctor; then, they used the probe attached to the pocket-sized TAUS device to acquire the follicle images. The doctor then measured the follicle diameter using a TVUS device and compared the measurements with those obtained by viewing the images taken by the patient. The transverse cross-sectional follicle diameter measured on transabdominal images was defined as the abdominal transverse (AT) diameter. The sagittal and coronal cross-sectional follicle diameters measured on transvaginal images were defined as the vaginal sagittal (VS) and vaginal coronal (VC) diameters, respectively. The mean values of each parameter and the variance ratio of the difference between the TAUS and TVUS measurements were evaluated.Results: The results showed that the difference between AT-VS in the two imaging types was -0.382 mm (95% CI: -1.097-0.333 mm, P=0.288), whereas the difference between AT-VC was 0.342 mm (95% CI: -0.345-1.029 mm, P=0.322), and that between VS-VC was 0.724 mm (95% CI: 0.152-1.296 mm, P=0.014). The variance ratios for the differences between the TAUS and TVUS measurements and for the differences between the two TVUS cross-sectional measurements were σAT-VS2/σVS-VC2=1.56 and σAT-VC2/σVS-VC2=1.44, respectively.Conclusion(s): Despite the presence of some differences in precision due to differences in the method of imaging when patients performed follicular self-measurement using pocket-sized devices, there was little scattering. Therefore, this method can be used to measure follicle diameter at a precision that presents no issues at the clinical level.Clinical Trial Registration Number: 2019001

scholarly journals Investigating the rate of different ovarian response in in vitro fertilization cycles based on estrogen receptor beta +1730 polymorphism: A cross-sectional study

2020 ◽  
Author(s):  
Elham Parsa ◽  
Seyed Mehdi Hoseini ◽  
Seyedeh Mahdieh Namayandeh ◽  
Zhima Akhavansales ◽  
Mohammad Hasan Sheikhha
Keyword(s):  
Estrogen Receptor ◽  
Estrogen Receptor Beta ◽  
Ovarian Response ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Vitro Fertilization ◽  
Reproductive Techniques ◽  
Receptor Beta

Background: The response to ovarian stimulation is different among women referring for assisted reproductive techniques. This difference could be due to different genotypes in genes related to reproduction such as estrogen receptor beta (ER

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