Evaluation of uterine cavity by hysteroscopic examination in infertile women in BSMMU

Background: Hysteroscopy is the gold standard procedure for uterine cavity exploration. However, hysteroscopy is only recommended by the WHO when clinical or complementary exams (ultrasound, HSG) suggest intrauterine abnormality or after in vitro fertilization failure. Nevertheless, many specialists feel that hysteroscopy is a more accurate tool.Objective: The aim of this prospective study is to find out the evaluation of uterine cavity by hysteroscopic examination as a primary workup of infertility. To asses the uterine pathology which is the causal factor for infertility.Method: This is a cross sectional study in which total 100 infertile patients were enrolled from infertility OPD in BSMMU with maintaining inclusion and exclusion criteria Hysteroscopy was performed with a standard sequence. The endocervical canal, uterine cavity, endometrium, and tubal ostia were inspected and findings were recorded. Results: Hysteroscopy was performed in 100 infertile women,among them 44% were presented with primary infertility and 56% presented with secondary infertility. The most common indication for diagnostic hysteroscopy was as a part of an infertility workup 80% cases. Other indication included abnormal hysterosalphingography, recurrent pregnancy loss and unexplained infertility. Hysteroscopy revealed a normal uterine cavity in 51 ( 51 % ) women (Table 2).among them majority of patients were primary infertility.and age less than 30 years. Hysteroscopic abnormalities are significantly high in secondary than primary infertility.Conclusion: In this study abnormal hysteroscopic findings were found in 49% who underwent diagnostic hysteroscopy. Our data are an additional argument to suggest that diagnostic hysteroscopy as part of investigation in infertile woman to evaluate uterine pathology. Routine diagnostic hysteroscopy should be part of an infertility workup in both primary and secondary infertility.At the same setting therapeutic approach also be possible which is beneficial for the patients.

Download Full-text

Major Depressive Disorder Association with Unsuccessful In-Vitro Fertilization (IVF) of Primary Infertile Women

International Journal of Contemporary Research and Review ◽

10.15520/ijcrr.v10i04.691 ◽

2019 ◽

Author(s):

Shalan Joodah Rhemah Al-Abbudi, M.B., Ch.B. F.I.B.M.S.Psych.

Keyword(s):

Depressive Disorders ◽

Cross Sectional Study ◽

Mental Illnesses ◽

Cross Sectional ◽

Vitro Fertilization ◽

Infertile Women ◽

Increased Risk ◽

High Prevalence ◽

Self Reporting Questionnaire

Background: Women who go through unsuccessful IVF treatment were at increased risk of depressive disorders. Objective: investigate the association between the unsuccessful IVF and depression among women with primary infertility. Methods: a cross-sectional study included infertile women attending fertility center. Socio-demographic and clinical variables were compiled. Self-Reporting Questionnaire (SRQ-20) to identify mental illnesses; DSM-V criteria for depression and Hamilton-17 Scale for severity of depression, were used. Results: high prevalence of depression among infertile women 80%. Unsuccessful IVF were 46%. About 26 % of infertile women with unsuccessful IVF were depressed. Depression was significantly associated with education, monthly income, duration of marriage, smoking, medication, chronic illness, and religion. Conclusion: Depressive disorders are the most frequently observed disorder among infertile women exposed to unsuccessful IVF

Download Full-text

Laparoscopic findings of infertile women at Bangabandhu Sheikh Mujib Medical University

Bangabandhu Sheikh Mujib Medical University Journal ◽

10.3329/bsmmuj.v7i2.29442 ◽

2016 ◽

Vol 7 (2) ◽

pp. 95

Author(s):

Shakeela Ishrat ◽

Farzana Deeba ◽

Jesmine Banu ◽

Afruna Rahman Diti

Keyword(s):

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Vitro Fertilization ◽

Tubal Patency ◽

Infertile Women ◽

Unilateral Block ◽

Medical University ◽

Work Up

Background: Laparoscopy is an important component of infertility work up. It is the gold standard for evaluation of pelvic pathology and assessment of tubal patency. Objective: The objective of the study was to analyze the laparoscopic findings of infertile women presenting at Infertlity unit of Bangabandhu Sheikh Mujib Medical University. Method: We had a retrospective cross-sectional study on Japaroscopic findings of 110 women. Results: Out of all patients 22.7% women had endometriosis. Various degrees of adhesion of pouch of Douglus was present in 16.4 %. Regarding tubal pate:1cy , 26.4% had unilateral block and 28.2% had bilateral block. Conclusion: A significant number of infertile women at the Infertility unit of BSMMU has tuboperitoneal disease and bilateral tubal block and ultimately need in vitro fertilization.

Download Full-text

Resilience, Perceived Stress, and Depressed Mood in Women Under in Vitro Fertilization Treatment

Reproductive Sciences ◽

10.1007/s43032-021-00685-1 ◽

2021 ◽

Author(s):

Carmen Fernandez-Ferrera ◽

David Llaneza-Suarez ◽

Daniel Fernandez-Garcia ◽

Vanesa Castañon ◽

Cristina Llaneza-Suarez ◽

...

Keyword(s):

Protective Effect ◽

Perceived Stress ◽

Depressed Mood ◽

Sleep Disturbances ◽

Depression Scale ◽

Short Version ◽

Cross Sectional ◽

Vitro Fertilization ◽

Infertile Women

AbstractIt has been suggested that women who display higher resilience levels may have less psychological distress during IVF. The aim of this study was to evaluate how infertile women deal with perceived stress, depressed mood, and sleep disturbances at the first IVF attempt and after one or more negative IVF outcomes depending on their level of resilience. An observational, cross-sectional study was carried out in a sample of 207 infertile women undergoing IVF procedures. The participants completed the short version of the Connor-Davidson Resilience Scale (CD-RISC), the short version of the European Spanish Version of Perceived Stress Scale (PSS-10), the Center of Epidemiologic Studies Depression Scale (CESD-10), and the Jenkins Sleep Scale (JSS). The relationship between CD-RISC scores ranked according to percentiles and mean PSS-10 scores revealed that women with strong resilience had lower perceived stress. After splitting the sample according to CD-RISC percentiles, differences were observed only at the first IVF attempt and the observed protective effect of high resilience scores appears to disappear following a negative IVF outcome. Women with high resilience are less likely to suffer from perceived stress or depressed mood during their first IVF attempt, this protective effect appears to be lost after a negative outcome.

Download Full-text

Transferrin and antioxidants partly prevented mouse oocyte oxidative damage induced by exposure of cumulus-oocyte complexes to endometrioma fluid

Journal of Ovarian Research ◽

10.1186/s13048-020-00738-0 ◽

2020 ◽

Vol 13 (1) ◽

Author(s):

Zi Ren ◽

Jiana Huang ◽

Chuanchuan Zhou ◽

Lei Jia ◽

Manchao Li ◽

...

Keyword(s):

Oxidative Damage ◽

Oocyte Retrieval ◽

Cross Sectional Study ◽

Human Oocyte ◽

Cross Sectional ◽

Vitro Fertilization ◽

Good Quality Embryo ◽

Damage Process ◽

Human And Mouse

Abstract Background Exposure of oocytes to the endometrioma fluid has an adverse effect on embryonic quality. To determine whether adding transferrin and antioxidants to culture medium could counteract detrimental effects on mouse cumulus-oocyte complexes (COCs) induced by exposure to endometrioma fluid or not, we conducted an in vitro cross-sectional study using human and mouse COCs. Methods Eighteen women who had their oocytes exposed to endometrioma fluid during oocyte retrieval were enrolled. COCs from superovulated ICR female mice were collected. They were first exposed to human endometrioma fluid and then treated by transferrin and/or antioxidants (cysteamine + cystine). Subsequently, COCs function was assessed by molecular methods. Results This study observed that human COCs inadvertently exposed to endometrioma fluid in the in vitro fertilization (IVF) group led to a lower good quality embryo rate compared to intracytoplasmic sperm injection (ICSI) group. Exposure of mouse COCs to endometrioma fluid accelerated oocyte oxidative damage, evidenced by significantly reduced CCs viability, defective mitochondrial function, decreased GSH content and increased ROS level, associated with the significantly higher pro-portion of abnormal spindles and lower blastocyst formation (p < 0.05, respectively). This damage could be recovered partly by treating COCs with transferrin and antioxidants (cysteamine + cystine). Conclusions Transferrin and antioxidants could reduce the oxidative damage caused by COCs exposure to endometrioma fluid. This finding provides a promising new possibility for intervention in the human oocyte oxidative damage process induced by endometrioma fluid during oocyte pick-up.

Download Full-text

Factors that influence in vitro fertilization treatment outcomes of Chinese men: A cross-sectional study

Applied Nursing Research ◽

10.1016/j.apnr.2016.07.003 ◽

2016 ◽

Vol 32 ◽

pp. 222-226 ◽

Cited By ~ 4

Author(s):

Dan Chen ◽

Jing Ping Zhang ◽

Ling Jiang ◽

Huayan Liu ◽

Ling Shu ◽

...

Keyword(s):

In Vitro Fertilization ◽

Treatment Outcomes ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Vitro Fertilization ◽

Chinese Men

Download Full-text

VAGINAL SONOGRAPHY a HYSTEROSCOPY

The Professional Medical Journal ◽

10.29309/tpmj/2009.16.03.2873 ◽

2009 ◽

Vol 16 (03) ◽

pp. 432-437

Author(s):

MASOMEH ASGHARNIA ◽

Zahra Mohammad Tabar ◽

MARZIEH MEHRAFZA ◽

Mary am Shakiba ◽

MONA OUDI ◽

...

Keyword(s):

Sensitivity And Specificity ◽

Uterine Cavity ◽

Cross Sectional Study ◽

Therapeutic Modality ◽

Histological Evaluation ◽

Complete Evaluation ◽

Cross Sectional ◽

Predictive Values ◽

Infertile Women ◽

Sensitivity Specificity

B a c k g r o u n d : Hysteroscopy is a valuable diagnostic and therapeutic modality in the management of infertility. A i m : To evaluatethe consistency of hysteroscopy based on a histopathological report from endometrial specimens for intrauterine disorders. Materials andMethods: This is a cross-sectional study. The study included 115 infertile patients. All were admitted for investigation of infertile women beforeassisted reproduction in Mehr infertility institute between 2006 and 2007 hysteroscopy, and histological evaluation of endometrial biopsyperformed.We compared the efficacy of hysteroscopy in the diagnosis of benign intrauterine pathology in infertile women in whom the diagnosiswas confirmed by histologic studies. The women had a complete evaluation with preoperative hysteroscopy, and histological analysis of uterinecavity specimens. Sensitivity, specificity, predictive and negative predictive values were calculated for hysteroscopy considering the histologicalstudy as 100%. Results: Sensitivity and specificity of sonography in diagnosing the polyp were stated 81 % and 64% respectively. Sensitivityand specificity of hysteroscopy showed of polyps revealed 85% and 84% respectively. The results indicated that Sensitivity and specificity ofsonography in diagnosing the myoma were 25% and 98% respectively. Sensitivity and specificity of hysteroscopy in diagnosing the myomawere expressed 50% and 93% respectively. C o n c l u s i o n : Hysteroscopy is a safe and rapid direct visualisation of the uterine cavity. We believeit should be replaced by the diagnostic hysteroscopy as a first line infertility investigation.

Download Full-text

Investigating Hysteroscopy Implementation in Infertile Women Candidate With a Normal Uterine Cavity for Laparoscopy in Hysterosalpingography

International Journal of Women s Health and Reproduction Sciences ◽

10.15296/ijwhr.2019.13 ◽

2018 ◽

Vol 7 (1) ◽

pp. 79-84

Author(s):

Maliheh Amirian ◽

Anis Darvish Mohammadabad ◽

Negar Morovatdar ◽

Leili Hafizi

Keyword(s):

Diagnostic Laparoscopy ◽

False Negative ◽

Uterine Cavity ◽

Cross Sectional Study ◽

P Value ◽

Cross Sectional ◽

Endometrial Polyps ◽

Infertile Women ◽

Submucous Myoma ◽

Age Range

Objectives: Endometrial pathologies inside the cavity can occur simultaneously with gestational unpleasant consequences but are not always capable of being diagnosed by the hysterosalpingography (HSG). This study aimed to examine the value of performing diagnostic hysteroscopy beside diagnostic laparoscopy among infertile women with normal uterine cavities in HSG. Materials and Methods: A total of 103 infertile women with normal uterine cavities in the HSG and within the age range of 18-40 who referred to Imam Reza hospital for laparoscopy during 2016-2017 were included in this cross-sectional study. Hysteroscopy was performed simultaneously with diagnostic laparoscopy. Then, the existence of uterine pathologies like endometrial polyps, submucous myoma, and uterine endometrial adhesions and their relationship with the patient’s age, infertility type and duration, and cycle time were evaluated. A P value less than 0.05 was considered statistically significant. Results: Overall, 64 patients (63.1 %) had a normal uterine cavity in the hysteroscopy while 39 of them had an abnormal uterine cavity, the HSG false negative cases of whom were reported 37.9%. The pathologies found in the hysteroscopy were endometrial polyp (16 cases), submucous myoma (1 case), uterine septum (6 cases), asherman syndrome (7 cases), bicornuate uterus (4 cases), polyp + asherman (3 cases), polyp + submucous myoma (1 case), and septum + submucous myoma (1 case). Patients’ age, type of infertility, and menstruation time during performing hysteroscopy made no particular difference in diagnosing pathologies of the uterine cavity in the hysteroscopy. Conclusions: Based on the findings, conducting hysteroscopy in infertile women who are candidates of laparoscopy and have normal uterine cavities in HSG can result in recognizing some cases of uterine pathologies which influence the outcomes of future pregnancies is not dependent upon the patient’s age, menstruation time, type and duration of infertility, and result of laparoscopy.

Download Full-text

Factors Related to the Number of Antral Follicles on InVitro Fertilization (IVF)

Indonesian Journal of Obstetrics and Gynecology ◽

10.32771/inajog.v4i2.79 ◽

2016 ◽

pp. 75

Author(s):

Fransiskus C Raharja ◽

Ketut Suwiyoga ◽

IPG Wardhiana

Keyword(s):

Prevalence Ratio ◽

Cross Sectional Study ◽

Chi Square ◽

Cross Sectional ◽

Vitro Fertilization ◽

Antral Follicles ◽

Chi Square Test ◽

The Mean ◽

Infertile Patients

Objective: To determine factors which are related to the number of antral follicles on infertile patients. Method: This cross sectional study was conducted in In-Vitro Fertilization (IVF) clinic of Graha Tunjung, Sanglah hospital, Bali. All fertile patients following the IVF program were calculated the number of antral follicles in both ovarian using transgene USG. This sample was recruited by random sampling from April 1st, 2001 to April 30th, 2011. We analyzed the data using Chi square test through SPSS for Windows 17.0 version. Result: Of 102 samples, the mean of patients’ age was 32.9% (SD 4.6) years old. From 72 patients (70.6%) experienced above 3 years of infertile period, the primary infertile was on 69 patients (67.7%). There was a relationship between patients’ age and the number of antral follicles significantly (prevalence ratio (PR) 1.41; 95% CI 1.11- 1.79). Meanwhile, the number of antral follicles and type of infertile (PR 1.02; 95% CI 0.76-1.37) also infertile period (PR 0.95; 95% CI 0.72-1.27) were not associated significantly. Conclusion: Patients’ age has an association with the number of antral follicles on IVF. [Indones J Obstet Gynecol 2016; 4-2: 75-77] Keywords: age, infertile, infertile period, number of antral follicles and type of infertile

Download Full-text

Evaluation of Uterine Cavity Abnormality using Saline Infusion Sonohysterography Before In Vitro Fertilization

Open Access Macedonian Journal of Medical Sciences ◽

10.3889/oamjms.2021.6884 ◽

2021 ◽

Vol 9 (B) ◽

pp. 917-920

Author(s):

Ichwanul Adenin ◽

Hilma Putri Lubis ◽

Binarwan Halim

Keyword(s):

In Vitro Fertilization ◽

Treatment Success ◽

Uterine Cavity ◽

Saline Infusion ◽

Infertile Woman ◽

Success Rates ◽

Endometrial Polyps ◽

Vitro Fertilization ◽

Saline Infusion Sonohysterography

BACKGROUND: Some studies suggested that saline infusion sonohysterography (SIS) has been used to detect uterine cavity abnormalities before in vitro fertilization (IVF) cycles to improve treatment success rates and decrease the number of cycle cancellations and embryo implantation failures. Some of the factors contributing to the dissemination and acceptance of the technique include the fact that it is a simple, less painful, less expensive, less invasive, and well-tolerated procedure when compared to hysteroscopy. AIM: The aim of the study is to evaluate uterine cavity abnormality with SIS performed before IVF. METHODS: A descriptive retrospective study involving 551 female partners who had SIS before IVF/ICSI treatment at private Halim Fertility Center from January 2014 until December 2017. Five hundred and fifty-one infertile woman was included in this study before IVF/ICSI cycles. Patients agreed to have an ultrasound assessment of the uterine cavity with the use of saline as the contrast medium. SIS procedure was scheduled postmenstrual period in the early-mid follicular phase and 1-3 months before starting IVF/ICSI treatment. RESULTS: From 551 patients, we found 527 (94.4%) cases with the normal uterine cavity. The uterine cavity abnormalities were detected in 5.56% of cases included in this study (28 (5.02%) cases with endometrial polyps, two (0.36%) cases with intrauterine adhesions, and one (0.18%) case with Müllerian duct anomalies). CONCLUSION: SIS before IVF treatment could be a good option for evaluating uterus cavity before IVF to improve success rates of pregnancy.

Download Full-text