Prevalence, Causes and Associated Risk Factors of Childhood Blindness – A Study in Tertiary Care Centre of Central India

OBJECTIVE: To review the epidemiology and associated risk factors for candidemia at a tertiary care centre, in view of recent reports on the changing epidemiology of bloodstream infection due toCandidaspecies.METHODS: Between January 2000 and December 2009, patients with blood culture samples positive forCandidaspecies were identified using the microbiology laboratory information system. Patient data were collected by retrospective chart review of clinical characteristics including demographic data, underlying medical diagnoses and risk factors.RESULTS: A total of 266 candidemia episodes were included in the final analysis. Fifty-nine per cent of these episodes occurred in males and 51% were in patients >60 years of age. The most common risk factor for candidemia was previous antibiotic use (85%). The most frequent species wasCandida albicans(49%), followed byCandida glabrata(30%).C albicanswas the predominant species in all study years with the exception of 2002, in whichC glabratawas more frequent. The likelihood of recovering a non-albicans Candidaspecies was found to be significantly associated with previous antifungal therapy (P=0.0004), immunosuppressive therapy (P=0.002), abdominal surgery (P=0.003) and malignancy (P=0.05). Mixed candidemia was found in 10 episodes (4%); 80% grewC albicansandC glabrata. Risk factors for mixed candidemia were not significantly different from those with monomicrobial candidemia.CONCLUSION:C albicansremains the most commonly isolated species in this setting, consistent with findings from other Canadian centres. However, non-albicans Candidaspecies were overall predominant. Mixed-species candidemia does not appear to be more prevalent in patients with identified risk factors.

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Clinico-Pathological Study of Tubal Ectopic Gestation and Evaluation of Associated Risk Factors in A Tertiary Care Centre

Annals of Pathology and Laboratory Medicine ◽

10.21276/apalm.2555 ◽

2019 ◽

Vol 6 (6) ◽

pp. A348-351

Author(s):

Archana S Bembde ◽

◽

Suparna M Bindu ◽

Chandrashekar P Bhale ◽

◽

...

Keyword(s):

Risk Factors ◽

Tertiary Care ◽

Care Centre ◽

Pathological Study ◽

Tertiary Care Centre ◽

Ectopic Gestation ◽

Associated Risk Factors

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Molecular Characterization of Carbapenem Resistant Isolates of Acinetobacter baumannii in An Intensive Care Unit of A Tertiary Care Centre at Central India

JOURNAL FOR CLINICAL AND DIAGNOSTIC RESEARCH ◽

10.7860/jcdr/2014/7749.4398 ◽

2014 ◽

Cited By ~ 5

Author(s):

Atul Khajuria

Keyword(s):

Intensive Care Unit ◽

Intensive Care ◽

Acinetobacter Baumannii ◽

Molecular Characterization ◽

Tertiary Care ◽

Central India ◽

Care Centre ◽

Tertiary Care Centre ◽

Carbapenem Resistant

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To study pattern of obstetric cases referred at tertiary care centre in Central India

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20172315 ◽

2017 ◽

Vol 6 (6) ◽

pp. 2370

Author(s):

Prakriti Goswami ◽

Jyoti Bindal ◽

Niketa Chug

Keyword(s):

Tertiary Care ◽

Mode Of Delivery ◽

Central India ◽

Maternal Outcome ◽

Child Health Services ◽

Care Hospital ◽

Care Centre ◽

Tertiary Care Centre ◽

Common Diagnosis ◽

Mode Of Transport

Background: Maternal morbidity and mortality remains a major challenge to health systems worldwide. Referral services for identification and referral of high risk pregnancies are an integral part of maternal and child health services. Timeliness and appropriateness of referral are challenge to obstetricians, since delay in referral affects maternal outcome adversely, hence the identification of at risk patients and obstetric emergencies and their timely referral is of immense importance. The aim of this study was to review the pattern of obstetric cases referred to tertiary care centre, to identify their clinical course, mode of delivery and maternal outcomes.Methods: It was prospective observational study carried out from January 2015 to July 2016. Study population was all Obstetrics patients referred to Department of Obstetrics and Gynecology of Kamla Raja Hospital, G.R. Medical College, Gwalior, Madhya Pradesh, a tertiary care centre during the study period.Results: The total number of referred cases in above study period was 4085.The proportion of referred cases in the tertiary care hospital was 20.86%. Mode of transport used by the referred patients were hospital ambulances (38%) and private vehicles (62%). Most common diagnosis at the time of referral was anaemia (27.8%). Out of the total referred cases, 48% had vaginal delivery (either spontaneous or induced), 28% had caesarean section and 24% were managed conservatively. Hypertensive disorders (25.4%) constitutes the leading cause of maternal deaths amongst the referred cases.Conclusions: Peripheral health care system needs to be strengthened and practice of early referral needs to be implemented for better maternal outcome.

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Clinical profile and risk factors for mortality among COVID-19 inpatients at a tertiary care centre in Bengaluru, India

Monaldi Archives for Chest Disease ◽

10.4081/monaldi.2021.1724 ◽

2021 ◽

Author(s):

Yamini Marimuthu ◽

Radhika Kunnavil ◽

NS Anil ◽

Sharath Burugina Nagaraja ◽

N Satyanarayana ◽

...

Keyword(s):

Risk Factors ◽

South India ◽

Linear Models ◽

Tertiary Care ◽

Male Gender ◽

Clinical Profile ◽

Rank Test ◽

Care Hospital ◽

Care Centre ◽

Tertiary Care Centre

COVID-19 is an emerging viral disease affecting more than 200 countries worldwide and it present with varied clinical profile throughout the world. Without effective drugs to cure COVID-19, early identification and control of risk factors are important measures to combat COVID-19. This study was conducted to determine the clinical profile and risk factors associated with mortality among COVID-19 patients in a tertiary care hospital in South India. This record-based longitudinal study was conducted by reviewing the case records of COVID-19 patients admitted for treatment from June 2020 to September 2020 in a tertiary care centre in South India. The clinical details, discharge/death details, were collected and entered in MS Excel. Potential risk factors for COVID-19 mortality were analysed using univariate binomial logistic regression, generalized linear models (GLM) with Poisson distribution. Survival curves were made using the Kaplan-Meier method. Log-rank test was used to test the equality of survivor functions between the groups. Out of 854 COVID-19 patients, 56.6% were men and the mean (standard deviation) age was 45.3(17.2) years. The median survival time was significantly lesser in male COVID-19 patients (16 days) as compared to female patients (20 days). Increasing age, male gender, patients presenting with symptoms of fever, cough, breathlessness, smoking, alcohol consumption, comorbidities were significantly associated with mortality among COVID-19 patients. Patients with older age, male gender, breathlessness, fever, cough, smoking and alcohol and comorbidities need careful observation and early intervention. Public health campaigns aimed at reducing the prevalence of risk factors like diabetes, hypertension, smoking and alcohol use are also needed.

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