scholarly journals P2Y2R activation by nucleotides released from the highly metastatic breast cancer cell contributes to pre-metastatic niche formation by mediating lysyl oxidase secretion, collagen crosslinking, and monocyte recruitment

Oncotarget ◽  
2014 ◽  
Vol 5 (19) ◽  
pp. 9322-9334 ◽  
Author(s):  
Young Nak Joo ◽  
Hana Jin ◽  
So Young Eun ◽  
Sang Won Park ◽  
Ki Churl Chang ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Metastatic Breast Cancer ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Lysyl Oxidase ◽  
Metastatic Breast ◽  
Metastatic Niche ◽  
Collagen Crosslinking ◽  
Monocyte Recruitment ◽  
Niche Formation

Reversal of the glycolytic phenotype by dichloroacetate inhibits metastatic breast cancer cell growth in vitro and in vivo

2009 ◽  
Vol 120 (1) ◽  
pp. 253-260 ◽  
Author(s):  
Ramon C. Sun ◽  
Mitali Fadia ◽  
Jane E. Dahlstrom ◽  
Christopher R. Parish ◽  
Philip G. Board ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Metastatic Breast Cancer ◽  
Cell Growth ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Metastatic Breast ◽  
Cancer Cell Growth ◽  
Breast Cancer Cell Growth

Matrix stiffness and cluster size collectively regulate dormancy versus proliferation in brain metastatic breast cancer cell clusters

2020 ◽  
Vol 8 (23) ◽  
pp. 6637-6646
Author(s):  
Raghu Vamsi Kondapaneni ◽  
Shreyas S. Rao
Keyword(s):  
Breast Cancer ◽  
Metastatic Breast Cancer ◽  
Tumor Cell ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Cluster Size ◽  
Metastatic Breast ◽  
Metastatic Tumor ◽  
Matrix Stiffness ◽  
Cell Clusters

Dormant versus proliferative phenotypes in metastatic tumor cell clusters are mediated via matrix stiffness and cluster size.

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