scholarly journals Practical Application of Dermatoglyphics in Disease Identification

2017 ◽  
Vol 03 ◽  
pp. 129
Author(s):  
Yuliana   ◽  
Keyword(s):  
Breast Cancer ◽  
Diabetes Mellitus ◽  
Down Syndrome ◽  
Bronchial Asthma ◽  
Environmental Changes ◽  
Postnatal Life ◽  
Practical Application ◽  
Intrauterine Environment ◽  
Genetic Studies ◽  
Disease Identification

Dermatoglyphics (fingerprint) indicates epidermal ridge patterns of sole, palm, fingers, and toes. It is unique for each person, because it is determined by interaction of genes and intrauterine environment. Once dermatoglyphic patterns are formed, it is not affected by age, development, and environmental changes in postnatal life. Therefore, they exhibit positive values in predicting various genetically influenced disorders. Dermatoglyphics plays an important role in medicolegal, anthropology, and genetic studies. Diabetes mellitus, hypertension, Down syndrome, bronchial asthma, schizophrenia, and breast cancer are some of the diseases that can be screened by dermatoglyphic identification.

Relationship between Diabetes Mellitus and Clinicopathological Stages of Breast Cancer at Diagnosis

2020 ◽  
Vol 0 (0) ◽  
pp. 0-0
Author(s):  
Ali Ali ◽  
Mohamed Mohamed ◽  
Nabil Khattab ◽  
Abd El Shafee Tabl ◽  
Reham Emam
Keyword(s):  
Breast Cancer ◽  
Diabetes Mellitus

Effects of Maternal Obesity and Gestational Diabetes Mellitus on the Placenta: Current Knowledge and Targets for Therapeutic Interventions

2020 ◽  
Vol 19 (2) ◽  
pp. 176-192
Author(s):  
Samantha Bedell ◽  
Janine Hutson ◽  
Barbra de Vrijer ◽  
Genevieve Eastabrook
Keyword(s):  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Maternal Obesity ◽  
Environmental Changes ◽  
Current Knowledge ◽  
Therapeutic Interventions ◽  
Placental Development ◽  
Exchange Site ◽  
And Function

: Obesity and gestational diabetes mellitus (GDM) are becoming more common among pregnant women worldwide and are individually associated with a number of placenta-mediated obstetric complications, including preeclampsia, macrosomia, intrauterine growth restriction and stillbirth. The placenta serves several functions throughout pregnancy and is the main exchange site for the transfer of nutrients and gas from mother to fetus. In pregnancies complicated by maternal obesity or GDM, the placenta is exposed to environmental changes, such as increased inflammation and oxidative stress, dyslipidemia, and altered hormone levels. These changes can affect placental development and function and lead to abnormal fetal growth and development as well as metabolic and cardiovascular abnormalities in the offspring. This review aims to summarize current knowledge on the effects of obesity and GDM on placental development and function. Understanding these processes is key in developing therapeutic interventions with the goal of mitigating these effects and preventing future cardiovascular and metabolic pathology in subsequent generations.

scholarly journals Metformin improves the outcomes in Chinese invasive breast cancer patients with type 2 diabetes mellitus

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Tianli Hui ◽  
Chao Shang ◽  
Liu Yang ◽  
Meiqi Wang ◽  
Ruoyang Li ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Cancer Patients ◽  
Invasive Breast Cancer ◽  
Breast Cancer Patients ◽  
Diabetes Group ◽  
Metformin Group

AbstractEarly reports indicate that metformin, a clinical drug administered to treat type 2 diabetes mellitus (T2DM), was found to be associated with a better prognosis of cancer. The objective of this study was retrospectively analyzed the effect of metformin on the outcomes of Chinese breast cancer patients with T2DM. A total of 3757 primary invasive breast cancer patients who underwent surgery from January 2010 to December 2013 were enrolled. According to the medication treatment, all the patients were divided as non-diabetes group, metformin group and insulin group. The follow-up data for disease-free survival (DFS) and overall survival (OS) were obtained from 3553 patients (median follow up of 85 months) and estimated with the Kaplan–Meier method followed by a log-rank test. Multivariate Cox proportional hazards regression model was applied. The results showed that there was a significant survival difference among non-diabetes group, metformin group and insulin group, 5-year DFS was 85.8%, 96.1%, 73.0%, and 5-year OS was 87.3%, 97.1%, 73.3% respectively (P < 0.05). Prognostic analysis showed metformin was significantly associated with better DFS and OS. Our results suggested that metformin may have a good effect on the survival of invasive breast cancer patients with T2DM.

scholarly journals Diabetes mellitus and risk of breast cancer: A meta-analysis

2007 ◽  
Vol 121 (4) ◽  
pp. 856-862 ◽  
Author(s):  
Susanna C. Larsson ◽  
Christos S. Mantzoros ◽  
Alicja Wolk
Keyword(s):  
Breast Cancer ◽  
Diabetes Mellitus ◽  
Meta Analysis

Breast reconstruction in breast cancer: update.

2021 ◽  
Vol 32 (2) ◽  
pp. 160-167
Author(s):  
I Capitán del Río ◽  
MA Rodríguez Cano ◽  
J Cámara Pérez ◽  
A Fierro Aguilar ◽  
MB Sánchez Andújar
Keyword(s):  
Breast Cancer ◽  
Diabetes Mellitus ◽  
Breast Reconstruction ◽  
Factores De Riesgo ◽  
Radioterapia Adyuvante

Resumen La reconstrucción mamaria es un elemento cada vez más presente en las Unidades de Mama debido al incremento de la realización de mastectomías reductoras de riesgo o profilácticas (MP) en pacientes portadoras de mutaciones de BRCA1/2. La decisión sobre la técnica y el momento idóneo para la reconstrucción depende fundamentalmente de la necesidad de radioterapia adyuvante, ya que ésta aumenta el riesgo de complicaciones tanto en las reconstrucciones autólogas como en las reconstrucciones basadas en implantes. En general, la reconstrucción inmediata es la opción preferible siempre que sea posible, ya que ofrece buenos resultados estéticos y evita mayor número de intervenciones quirúrgicas. Cuando ésta no es factible inicialmente, existe la posibilidad intermedia de colocación de expansores que permite alcanzar un mayor volumen mamario mediante la expansión progresiva de los tejidos, como terapia puente a la implantación de una prótesis definitiva. Dentro de las técnicas reconstructivas diferidas existen desde el colgajo miocutáneo de dorsal ancho hasta las variantes microquirúrgicas como el DIEP. Para la selección de una de estas técnicas se debe tener en cuenta la morfología de la paciente, el remanente cutáneo y el estado vascular de la paciente, así como los factores de riesgo que puedan interferir en la viabilidad de los colgajos (hábito tabáquico o diabetes mellitus, entre otras) para la consecución de un plan quirúrgico óptimo.

Ulcerated disseminated cutaneous leishmaniasis associated with vitiligo, hypothyroidism, and diabetes mellitus in a patient with Down syndrome

2004 ◽  
Vol 10 (2) ◽  
Author(s):  
Shahin Aghaei ◽  
Rahmat Salmanpour ◽  
Farhad Handjani ◽  
Ahmad Monabati ◽  
Nazila Mazharinia ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Down Syndrome ◽  
Cutaneous Leishmaniasis

PO119 IMMUNE REACTIVITY IN PATIENTS WITH BREAST CANCER ASSOCIATED WITH TYPE 2 DIABETES MELLITUS

The Breast ◽  
2013 ◽  
Vol 22 ◽  
pp. S60
Author(s):  
Natalia Botnariuc ◽  
Larisa Sofroni ◽  
Vasile Jovmir ◽  
Diana Tcaciuc ◽  
Valentina Stratan ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Immune Reactivity
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