Prospective Analysis of Etiologies of Nose Defects in a Tertiary Care Referral Centre

The purpose of the study was to analyze the various causes of nasal defects seen in practice by plastic surgeons in the Department of Plastic Surgery, in a tertiary care North Indian Hospital. The study included all patients of any age and sex presenting to the outpatient department or emergency department with nose defects. The patients were enquired about the cause and history of their nasal defects. The most common etiologies of nasal defects seen were skin tumors of the nose, the most common one being the basal cell carcinoma (BCC) followed by squamous cell carcinoma (SCC), and congenital naevus. Both the malignancies BCC and SCC were seen in older age. While BCC was significantly more common in males, a specific gender preference could not be concluded in SCC. Trauma was the next most common cause and included road traffic accidents, assaults, and animal bites. These were more commonly seen in the youth and less commonly in geriatric or pediatric populations. Other less common causes of nasal defects included postburn lesions.

Management of Cut and Dry Bamboo Borer - Chlorophorus annularis Fab. (Coleoptera: Cerambycidae) by Using Systemic and Contact Insecticides

Chlorophorus annularis Fab. (Coleoptera: Cerambycidae) damages cut and dry bamboo. Chlorpyriphos 0.04% yielded 39.13 percent for the control of bamboo borer followed by chlorpyriphos 0.02%, which controlled 34.78% of borer attacks while cypermethrin and deltamethrin were found least effective. Among the systemic insecticides, imidacloprid 0.04% gave 26.32 percent control of borer attack.

Priapism in a Healthy Male: A Rare Side Effect of Herbal Medicines Containing Withania somnifera

Priapism is an uncommon urological emergency. Drugs are known causes of priapism. Self-medication and use of over-the-counter drugs are very common in India. Withania somnifera is common over the counter herb used in India for anxiety, depression, boosting immunity, infertility, etc. Despite the unprohibited and over-the-counter use of drug, the efficacy and adverse events data are not available. We report a patient of anxiety and depression self-medicating with W. somnifera and multivitamins presenting with ischemic priapism.

Epidemiology and Outcome in Electrical Burn Injury: Retrospective Study of 282 Patients in a Tertiary Care Hospital of Western Uttar Pradesh, India

Electrical burns account for a small percentage of all burn injuries. However, in burn patients, they are a major source of disability. They put socioeconomic burden on the society. This is a retrospective epidemiological study of 282 electrical burn patients admitted in burn unit of a tertiary care hospital of North India. Majority of the electrical burn was due to accidental touching of uncovered wires and occupation-related burns in laborers and industrial workers who were mainly young males in the age group 20 to 40 years. Most of the cases were of high-voltage (≥1000 V) electrical burns. More severe burns, longer hospital stays, and more problems and operations were all linked to high-voltage burns. Amputation rates for high-voltage burns were significantly higher (37.3%) as compared to low-voltage burns (13.6%). Electrical burn injuries can be prevented by awareness programs, proper training, and safety measures both by public and government.

The Versatility of Autologous Fat Grafting in Facial Volumetric Restoration

Deformities in the craniofacial region are of great social and functional importance. Several surgical techniques have been used to treat such pathologies often with high morbidity and lacking the ability to address smaller contour defects. The minimally invasive technique of fat transplantation has evolved rapidly within the last few decades. The objective of this paper is to present the versatility and applicability of fat transplantation in a wide range of contour deformities in the craniofacial region. We share our experiences in treating 24 patients with autoimmune disorders, congenital malformations, and acquired defects.

A Rare Pediatric Case Report With Review of Literature for the Diagnosis of Acute Megakaryoblastic Leukemia (FAB M7)

Acute megakaryoblastic leukemia (AMKL) is a subtype of acute myeloid leukemia (AML) accounting for 3%–10% of primary AML in childhood. Clinical manifestations of AML patients can include low grade of fever, diarrhea, easy bruising, failure to growth, and life-threatening clinical manifestations. Laboratory tests are very crucial to make a definitive diagnosis and treatment. We report here an uncommon case of AMKL in a 12-month-old boy who presented with general paleness and fatigue. Based on blood film investigation, bone marrow examination report, and immunophenotyping, he was diagnosed as a case of AMKL without Down syndrome.

Postburn Hand Deformities: Principles of Management and Approach

The hand is one of the top 3 locations for burn scar contracture deformity. The functionality of the hands is one of the primary determinants of burns survivors’ quality of life. Although most burn abnormalities are preventable, they do arise when adequate treatment is not delivered in an emergency or when they are part of a major burn. Reconstructive surgeries can significantly improve hand function. For a burn’s survivor, the right methods and timing of surgery, followed by supervised physiotherapy, can be a game changer.

Morphological Parameters of the Myocardium in Spontaneously Hypertensive Rats upon Administration of Propylthiouracil

The morphological changes in myocardial tissue in spontaneously hypertensive rat (SHR) occurring after administration of propylthiouracil (PTU) were assessed in the project. PTU at a concentration of 0.1% was given to the animals with drinking water for 47 days. After the end of the experiment, the morphological parameters of cardiomyocytes, the density of cardiomyocytes and fibroblasts in the myocardium, and the average area of the lumen of veins were examined. The progressive development of dystrophic processes in the myocardium was established against the background of PTU intake, which was characterized by a decrease in the cardiomyocyte density and an increase in the volume of connective tissue, venous congestion, and expansion of the lumen of veins.

COVID-19 Fear Among Health Care Workers (HCW) and Non-HCW in IGMC, Shimla: An Online Questionnaire-Based Prospective Study

The unremitting COVID-19 pandemic is evoking anxiety, fear, panic, and socio-occupational stress among human population all around the globe. This cross-sectional study was planned to assess the fear and anxiety because of COVID-19 pandemic among health care professionals, patients, and general public in IGMC, Shimla. A cross-sectional, web-based survey was conducted in month of December 2020. COVID-19 fear questionnaire was used to assess fear among participants. A total of 162 responses were received. Ninety-five (41.35%) respondents were males and 67(58.64%) were females. Average total score of COVID-19 fear based on questionnaire was 17.71 among the participants. The majority of respondents 67(41.4%) were afraid of COVID-19, 53(32.7%) were neutral, whereas 42 (25.9%) were not afraid of COVID-19. Sixty-two (38.3%) responders were uncomfortable thinking about COVID-19, whereas, 67(41.4%) were not uncomfortable. Only 22 (13.6%) participants felt their hands clammy when they thought of COVID-19, 78 (48.15%) respondents were afraid of losing their life, 78 (48.15%) respondents disagreed with the question of being nervous or anxious to hear news and stories of COVID-19. Thirteen (8%) participants were informed of sleeplessness, and 22 (13.5%) reported palpitations due to COVID-19 fear. COVID-19 fear was evident in 65.15% of all males and 55.8% of all females’ respondents, respectively. Seventy percent of participants of age more than 40 years were afraid of COVID-19, whereas only 54.83% participants of less than 40 years had COVID-19 fear. COVID-19 fear was more evident among non-HCW (74.42%) as compared to HCW in whom it was seen in 53.03% participants. Rampaging Pandemic has ingrained fear and anxiety among non-HCW as well as health care workers. But undeterred by COVID-19 fear, majority of participants didn’t fear death and didn’t have other effects of fear. Despite (can be used) surging pandemic when fear of COVID-19 is soaring, HCW and non-HCW could work, think, and live.

Cardiac Health Indicators in Critical COVID-19 Cases

Coronavirus disease-2019 (COVID-19) is an infectious disease that has spread worldwide and led to ongoing global concern. The pandemic prompted researchers to examine the impact of COVID-19 on human organs. The heart is one such organ. This study investigates the possible prediction of heart condition using some biochemical markers of particularly critically ill patients referred to an intensive care unit (ICU). Results of various serum biomarkers of patients infected with COVID-19 receiving treatment in the ICU, Asir Central Hospital, Asir Region, Saudi Arabia, were extracted and compared with healthy individuals using the Mann-Whitney U test. The study showed a distinguished increase in total Serum creatine phosphokinase-Total (CPK-Total), Serum creatine phosphokinase-MP (CPK-MP) levels among COVID-19/ICU patients. But, this increase was not statistically significant. Besides, aspartate aminotransferase, alanine aminotransferase, and lactate dehydrogenase levels revealed a statistically significant increase in the infected group compared with controls. Examination of electrolytes showed a reduction in calcium median value in COVID-19/ICU patients. Data revealed a possible influence of COVID-19 on the heart. Herein, we observe significant parameters that may reflect cardiovascular injury elicited by the virus. These biomarkers possibly used to monitor the severity of disease on the cardiovascular system.