Background: Rosa canina L. has high levels of carotenoids, flavonoids and, vitamin C antioxidant compounds that can withstand the destructive effects of exhaustive exercise-induced oxidative stress. The present study aims to investigate the effects of concurrent eight-week aerobic training and Rosa canina L. fruit hydroalcoholic extract on some liver enzymes and malondialdehyde of liver in male rats following an acute aerobic exercise until exhaustion. Methods: The present research was an experimental study. Forty male Wistar rats were randomly divided into four groups (N=10): placebo (without exercise + distilled water 2 ml supplement), supplement (without exercise + Rosa canina L extract, 100 mg/kg), exercise (8 weeks exercise + distilled water 2 ml), combined (8 weeks exercise + Rosa canina L extract, 100 mg/kg). At the end of the experiment, half of the rats were killed immediately before exhaustive exercise; while the other half were killed immediately after performing an acute exhaustive exercise on the treadmill. Serum enzymes AST, ALT, and hepatic malondialdehyde levels were measured by ELISA and thiobarbituric acid methods, respectively. Results: The results show that in all groups except the combined group serum AST, ALT, and malondialdehyde of the liver were significantly increased following an acute exhaustive exercise compared to the prior exhaustive exercise (P<0.05). Conclusion: The use of Rosa canina L Fruit hydroalcoholic extract with aerobic exercise prevented the increase of hepatic malondialdehyde and serum enzymes AST, ALT levels following an acute exhausting exercise.
Antidiabetic effect and glucose tolerance of areca nut (Areca catechu) seed ethanol extract on alloxan-induced diabetic male rats
