Comparison of Two Transcutaneous Bilirubinometers in Term and Near-Term Neonates

2014 ◽  
Vol 33 (3) ◽  
pp. 138-142 ◽  
Author(s):  
Serdar Umit Sarici ◽  
Esad Köklü ◽  
Oguzhan Babacan

Purpose: Determination of bilirubin levels is performed for many newborns in the first days of life, and several different transcutaneous bilirubinometers are available. We aimed to determine whether transcutaneous bilirubin measurement, as performed using Jaundice Detector JH20-1C, a new device, correlates with Minolta/Hill-Rom Air-Shields Transcutaneous Jaundice Meter model JM-103.Design and Sample: The study was performed on term or near-term newborn infants who underwent transcutaneous bilirubin measurements as part of their normal care. The study group consisted of 585 newborn infants with gestational ages ranging from 35 to 42 weeks, coming from an uneventful pregnancy. In this prospective study, bilirubin concentrations were determined with two different transcutaneous bilirubinometers.Main Outcome Variable: In 585 infants, the correlation coefficient for Jaundice Detector JH20-1C versus Minolta Air-Shields Jaundice Meter model JM-103 was .965 (p < .0001). The mean (± standard deviation) difference between the Jaundice Detector JH20-1C versus Minolta Air-Shields Jaundice Meter model JM-103 was 0.26 ± 0.95 mg/dL. Results showed the Jaundice Detector JH20-1C to have an acceptable level of intradevice imprecision (r = .978, p < .0001, mean differences .0158 ± .871 mg/dL).Results: Jaundice Detector JH20-1C showed the good performances of intradevice and interdevice imprecision in comparison with Minolta/Hill-Rom Air-Shields Transcutaneous Jaundice Meter model JM-103. Jaundice Detector JH20-1C may be suitable for screening term or near-term newborn infants for jaundice in the well-baby nursery or maternity ward.

Author(s):  
Dr. Ram Manohar Kurrey ◽  
Dr. Kavita J. Lall ◽  
Dr. Karan Singh Chandrakar

In this study we evaluate the activity of lipid profile in premature, near term and term neonates. A total number of 68 newborn infants were selected for this study. They were delivered normally, or by caesarean section, and their gestational age was included. The infants with congenital anomalies or those, whose mothers had medical problems, were excluded from the study. The gestational age was determined according to the date of the last menstrual period, or the early ultrasound in 20 weeks of gestation. All the information related to the newborns and their mothers were recorded in the prepared forms. Following the delivery, blood samples were taken from the umbilical cord immediately, and were separated after clotting, for at least 30 min at room temperature. Serum was stored at 4°C to -80C for a maximum of 2 days, prior to the analysis. Total cholesterol, triglycerides and HDL were analyzed by enzymatic method using auto-analyzer. Serum Total Cholesterol estimated by enzymatic kit method, Triglyceride estimated by bioluminescent assay method and HDL-cholesterol estimated by phasphotungstate precipitation method manufactured by ERBS Transasia. LDL-C and VLDL-C calculated by Friedewald formula. The three groups were significantly different, regarding the means of age, weight and cholesterol and LDL-C level, whereas no significant difference was observed concerning the level of triglyceride and HDL-C,. Gender has no effect on the level of cholesterol, triglyceride, HDL-C and LDL-C in the total population and in all subgroups (P value more than 0.05). On the basis of present study we assume that the cholesterol level was higher in those with prematurity and pre-term delivery, and is also inversely correlated with the infant’s birth weight. Therefore, we believe that monitoring, observation and early-lifestyle modifications may decrease the severity of atherosclerosis in the vessels in adulthood. This study says, it is evident that the total cholesterol and LDL cholesterol in premature and near term neonates was higher than a term neonates ; triglyceride and VLDL were higher in term neonates as compared to near term neonates. Fall in HDL was significantly observed in premature neonates than term neonates and near term neonates but no significance found in term and near term neonates.


QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Hisham A Awad ◽  
Basma M Shehata ◽  
Marina A Fouad

Abstract Background Neonatal hyperbilirubinemia is common in the neonatal period. Yet, serious pathological hyperbilirubinemia may cause kernicterus with detrimental neurologic sequalae. Carbon monoxide (CO) is the byproduct of the breakdown of heme, it is transported as carboxyhemoglobin to the lungs to be exhaled. Thus, carboxyhemoglobin levels increase as a result of hemolysis, and is therefore considered a sensitive index for the degree and severity of the subsequent hyperbilirubinemia. Objectives To correlate between non-invasive carboxyhemoglobin levels and bilirubin levels in near-term and tem neonates starting hour I of life. Subjects and methods A total of 100 near-term and term neonates were studied, by measuring carboxyhemoglobin by a Pulse CO-oximetry and serum bilirubin level (hour l) and transcutaneous bilirubin (TcB) hourly since birth for the I st 6 hours then every 6 hours till the time of discharge in a cross sectional case-control study. Results A cut off value of 4 for non-invasive carboxyhemoglobin with sensitivity of 81.25%, specificity of 95.24% was found to the earliest non-invasive predictor for subsequent jaundice. In patients with proven hemolysis, carboxyhemoglobin when compared to TcB was found to increase significantly in the first 3 hours of life more than TcB, stalting hour 4 till time of discharge it was increased yet statistically insignificant Conclusion We found that non-invasive carboxyhemoglobin is an effective early predictor for subsequent jaundice starting first hour of life. It can be used as a screening tool for hemolytic jaundice especially in hospitals with early discharge policy.


2007 ◽  
Vol 150 (3) ◽  
pp. 235-240.e1 ◽  
Author(s):  
G. Ganesh Konduri ◽  
Betty Vohr ◽  
Charlene Robertson ◽  
Gregory M. Sokol ◽  
Alfonso Solimano ◽  
...  

2004 ◽  
Vol 23 (4) ◽  
pp. 25-32 ◽  
Author(s):  
Jennifer Anne Dawson ◽  
M. Colleen Stainton

Purpose: To examine the effect of the Australian Safe-n- Sound Baby Safety Capsule (BSC) on oxygen saturation (SpO2) values of preterm and term infants ready for discharge home.Design: A two-group pretest/posttest quasi-experimental study compared the effect of the BSC on SpO2.Sample: Thirty-nine low birth weight premature newborn infants and 19 term newborn infants ready for discharge home.Main outcome variable: Mean oxygen saturation values and the number of oxygen desaturation events below 90 percent.Results: The mean SpO2 values for both preterm and term infants were within the normal range (>90–100 percent) for each phase of data collection (baseline, capsule, and recovery). However, mean SpO2 values decreased from baseline during the 60 minutes spent in the BSC for the preterm infants.


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