scholarly journals Effects of Prolonged Empirical Antibiotic Administration on Post-Surgical Intestinal Bacterial Flora of Local Dogs Undergoing Non-Laparoscopic Gastrectomy

2015 ◽  
Vol 7 (3) ◽  
pp. 40-48
Author(s):  
J.F. Akinrinmade ◽  
Gladys O. Melekwe ◽  
Adenike A.O. Ogunshe
1977 ◽  
Vol 47 (2) ◽  
pp. 228-235 ◽  
Author(s):  
Hewitt C. Goodpasture ◽  
Donald A. Romig ◽  
Douglas W. Voth ◽  
Chien Liu ◽  
Charles E. Brackett

✓ The authors observed prospectively 28 brain-injured patients, who required respiratory tract intubation, to determine the effect of antibiotic prophylaxis on bacterial flora, the rate of flora change, and the appearance of infection. Antibiotics not only failed to alter the rate of abnormal colonization but were associated with an earlier appearance of Gram-negative bacilli, the organisms that produced the most severe infections. Although more infections occurred in patients initially untreated with antibiotics, these infections were usually mild and caused by organisms susceptible to highly effective and relatively safe drugs. Although highly reproducible as a laboratory determination, the nitroblue tetrazolium dye test score showed no consistent relationship with the presence or absence of bacterial infection. Regular and extensive clinical and laboratory observations, including cultures of the respiratory tract, helped to make the antibiotic administration in these patients specific, appropriate, and reasonable. Broad spectrum antibiotic prophylaxis does not prevent and may enhance the development of severe pulmonary infection in these patients.


Author(s):  
Tejas A. P. ◽  
Revanasiddappa . ◽  
Hariprasad T. R. ◽  
Rohit K.

Fournier's gangrene is a rare, idiopathic, life threatening, necrotising fascitis of the genitals and perineum caused by both aerobic and anaerobic bacterial flora. The synergistic effect of the bacteriae results in fulminating gangrene, multiple organ failure and death. Most commonly it has predilection for diabetic and alcohol abused individuals. Timely recognition of the disease process and initiation of treatment with aggressive debridement and antibiotic administration is called for. In this case report, we recall an account of our tryst with Fournier's gangrene management.


2020 ◽  
Vol 477 (14) ◽  
pp. 2679-2696
Author(s):  
Riddhi Trivedi ◽  
Kalyani Barve

The intestinal microbial flora has risen to be one of the important etiological factors in the development of diseases like colorectal cancer, obesity, diabetes, inflammatory bowel disease, anxiety and Parkinson's. The emergence of the association between bacterial flora and lungs led to the discovery of the gut–lung axis. Dysbiosis of several species of colonic bacteria such as Firmicutes and Bacteroidetes and transfer of these bacteria from gut to lungs via lymphatic and systemic circulation are associated with several respiratory diseases such as lung cancer, asthma, tuberculosis, cystic fibrosis, etc. Current therapies for dysbiosis include use of probiotics, prebiotics and synbiotics to restore the balance between various species of beneficial bacteria. Various approaches like nanotechnology and microencapsulation have been explored to increase the permeability and viability of probiotics in the body. The need of the day is comprehensive study of mechanisms behind dysbiosis, translocation of microbiota from gut to lung through various channels and new technology for evaluating treatment to correct this dysbiosis which in turn can be used to manage various respiratory diseases. Microfluidics and organ on chip model are emerging technologies that can satisfy these needs. This review gives an overview of colonic commensals in lung pathology and novel systems that help in alleviating symptoms of lung diseases. We have also hypothesized new models to help in understanding bacterial pathways involved in the gut–lung axis as well as act as a futuristic approach in finding treatment of respiratory diseases caused by dysbiosis.


1969 ◽  
Vol 100 (1) ◽  
pp. 29-32 ◽  
Author(s):  
S. A. Friedman

JAMA ◽  
1966 ◽  
Vol 196 (13) ◽  
pp. 1125-1127 ◽  
Author(s):  
G. H. Bornside

2008 ◽  
Vol 1 (1) ◽  
pp. 17-22
Author(s):  
Turgut KARLIDAĞ ◽  
Ahmet KİZİRLİGİL ◽  
Erol KELEŞ ◽  
Hayrettin Cengiz ALPAY ◽  
İrfan KAYGUSUZ ◽  
...  
Keyword(s):  

Author(s):  
Bugero N.V. ◽  
Aleksandrova S.M.

Foundries in manufacturing plants are characterized by hazardous working conditions. The paper makes an assessment of industrial health hazards, identifies groups of diseases dominant among the examined individuals. It is clear that gastrointestinal diseases make the largest percentage. The effect of destabilizing industrial factors that lead to the intestinal biome restructuring, help reduce the dominant microorganism’s group and increase opportunistic flora has been determined. The severity of this indicator correlates with professional working experience. Along with the fecal matter bacterial flora of the examined people, the protozoa that belong to the parasitic group (blastocysts, lamblia, amoeba) were identified, and Blastocystis spp. has the largest proportion. The biological properties of blastocysts were studied exemplified by anticarnosine activity (AcrA), which allows them to colonize the intestinal mucous membranes and helps displace obligate symbiotes against the decrease in the overall resistance of the macroorganism. The data obtained make it possible to forecast human health state under the conditions of anthropogenic-disturbed territories and plan measures to improve and protect workers’ health.


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