scholarly journals In Vitro Assessment of Nickel Ion Release from Orthodontic Wires

2019 ◽  
Vol 4 (4) ◽  
2021 ◽  
Vol 2021 ◽  
pp. 1-10
Author(s):  
Lina M. Escobar ◽  
Jaime Rodrigo Rivera ◽  
Eliana Arbelaez ◽  
Luisa F. Torres ◽  
Andrea Villafañe ◽  
...  

Orthodontic wires are made of alloys containing different metals, including nickel. It is important to evaluate their biocompatibility prior to use, owing to their long-term use in patients. This in vitro study compared the cytotoxicity and chemical composition of six latest orthodontic wires: Fantasia®, Tanzo®, FLI®, NT3®, DuoForce®, and Gummetal®. The before-use group consisted of wires that were not used in the mouth, and the after-use group consisted of wires that were used in the mouth for two months. The wires were placed in contact with human gingival fibroblasts (HGF) for 72 h, and cytotoxicity was determined using the resazurin test. The chemical composition and surface characterisation were evaluated by spectrometry and scanning electron microscopy. The groups were compared using ANOVA and Kruskal–Wallis test. Only the FLI® wires produced a 36% reduction in HGF viability ( p < 0.05 ) and presented greater irregularities and loss of polymer structure. After-use wires showed a significant reduction in the percentage of nickel and the appearance of new elements (oxygen and carbon). Therefore, it can be concluded that no toxic ion release was noticed in this study. Rhodium-coated wires were more stable than PTFE-coated wires, and only the FLI® wires showed a slight cytotoxic effect.


2020 ◽  
Vol 53 (2) ◽  
pp. 67
Author(s):  
Hilda Fitria Lubis ◽  
Kholidina Imanda Harahap ◽  
Dina Hudiya Nadana Lubis

Background: Stainless steel is a material that can be used in orthodontics for components of dental braces, such as brackets, archwires and molar bands. Orthodontic archwires exposed to toothpaste can release nickel ions that cause hypersensitivity. The excessive use of sodium lauryl sulphate in detergent toothpaste can cause mouth irritation, severe ulceration, decreased salivary solubility and taste sensitivity changes. Purpose: The aim of this study is to compare the nickel ion released by stainless steel archwires after immersion in detergent and non-detergent toothpaste. Methods: Forty stainless steel archwires from Ortho Organizer (0.016 x 0.022in) were divided into two groups (n=20). Group 1 comprised stainless steel archwires immersed in detergent toothpaste. Group 2 consisted of stainless steel archwires immersed in non-detergent toothpaste. These archwires were immersed in 1.5g toothpaste then kept in an incubator at 37°C for around 24 hours. After that, the archwires were removed from the toothpaste, and the toothpaste was dissolved in 25ml of Aquadest. The amount of nickel ion released was examined by using inductively coupled plasma optical emission spectrometry (ICP-OES). After that, the structure of the sample surface was examined with a scanning electron microscope (SEM). A statistical analysis was done using the Shapiro–Wilk normality test (p>0.05). An independent t-test was carried out to compare the two groups (p<0.05). Results: The mean of nickel ion release in group 1 was 0.214±0.319mg/l, and in group 2 it was 0.168±0.107 mg/l. There was no significance between the groups (p=0.323; p>0.05). The SEM images of the archwire surfaces showed that there were more corrosive contour changes in the archwire surface in group 1 than in group 2. Conclusion: There was no difference between the nickel ion released from stainless steel orthodontic archwires after immersion in detergent and non-detergent toothpaste. After immersion in detergent toothpaste, stainless steel archwire surfaces showed more corrosive contour changes than those immersed in non-detergent toothpaste.


2021 ◽  
Vol 11 (20) ◽  
pp. 9745
Author(s):  
Arata Ito ◽  
Hideki Kitaura ◽  
Haruki Sugisawa ◽  
Takahiro Noguchi ◽  
Fumitoshi Ohori ◽  
...  

The leaching of metal ions from orthodontic appliances is a problem for their use in patients with metal allergies. Despite the development of a number of non-metal orthodontic appliances, including brackets, non-metal wires are not yet available. Therefore, it is necessary to modify the surfaces of orthodontic wires to prevent the leaching of metal ions into the oral environment for use in such patients. This study was performed to examine whether plating of orthodontic wire with titanium nitride (TiN), which does not impair its mechanical properties, could prevent the leaching of metal ions from the wire on immersion in acid. To investigate the acid corrosion resistance of the wire, the amount of metal ions eluted from the wire immersed in acid was measured by using inductively coupled plasma mass spectrometry (ICP-MS) and the dimethylglyoxime (DMG) test, the properties of the wire surface were examined by stereomicroscopy and scanning electron microscopy, and the surface roughness was measured using a surface roughness tester. The results indicated that TiN plating of orthodontic wire significantly suppressed the elution of metal ions on immersion in acid.


Author(s):  
Anila Charles ◽  
Parag Gangurde ◽  
Sanjay Jacob ◽  
Suruchi Jatol-Tekade ◽  
RS Senkutvan ◽  
...  

2019 ◽  
Vol 66 (6) ◽  
pp. 746-756 ◽  
Author(s):  
Elnaz Moslehifard ◽  
Sanaz Ghasemzadeh ◽  
Farzad Nasirpouri

Purpose The purpose of this paper (in vitro) study was to determine the effect of pH of artificial saliva on the corrosion behavior of a Ni-Cr-Mo alloy at 37 ± 1°C. Design/methodology/approach The corrosion behavior of a commercially available Ni-Cr-Mo base dental alloy was studied by potentiodynamic polarization and electrochemical impedance spectroscopy techniques. The effect of pH on corrosion and Ni ion release was also investigated by scanning electron microscopy and atomic absorption spectroscopy. Findings The results suggested that the order of corrosion rate was: pH3 > pH5 > pH9 > pH7. Corrosion rate in pH3 was significantly different with other pH levels. Nickel depletion significantly occurred in alloy without passivation. The corrosion resistance and ion release of Ni-Cr-Mo alloys in different pH levels of artificial saliva depended on the stability of the passive layer. Acidic pH level severely corrodes Ni-Cr-Mo base metal alloys and increases Ni ion release. Originality/value This manuscript describes the relationship between corrosion rate and nickel ion release of a dental Ni-Cr-Mo base alloy as a function of saliva pH examined by electrochemical impedance spectroscopy (EIS), polarization, scanning electron microscopy and energy dispersive X-ray spectroscopy in artificial saliva. The main novelty of this work includes the material/structure/corrosion relationship in artificial saliva with different pH. This property would be very interesting for dental materials applications and clinical dentistry.


Materials ◽  
2021 ◽  
Vol 14 (22) ◽  
pp. 7069
Author(s):  
Dessy Rachmawati ◽  
Devanti Ayu Cahyasari ◽  
Ardin Tito Febiantama ◽  
Lusi Hidayati ◽  
Cornelis Johannes Kleverlaan

Alloys in oral cavity always interact with dynamic oral environment, such as pH, temperature, salivary conditions, and dietary habits. Coffee can further decrease pH in the oral cavity. Thus, coffee may increase the release of metal ions that may lead to various health diseases. This study aimed to quantitively investigate the effect of brewed Robusta coffee on the nickel ion release and their morphological structures; Methods: 20 alloy specimens were divided into 4 groups and placed in solutions for 48 and 168 h: (1) distilled water, (2) artificial saliva, (3) Robusta coffee, and (4) mixture of artificial saliva and Robusta coffee. AAS, XRF, and SEM were used for examinations; Results: The release of Ni2+ was found in all groups and robust release were found in the coffee only and mixture of coffee + artificial saliva solution after 168 h. Likewise, SEM showed that internal oxidation was high after 168 h of immersion; Conclusions: The concentration of nickel increased in saliva of low pH due to brewed coffee. Though the release of these ions is still within the tolerable amount in human body, it should be realized that it usually lasts for months or years. Dentists should be cautious when using instructions for patients with a history of allergies especially for dietary with low acidity.


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