Runx2 rs59983488 polymorphism in class II malocclusion in the Indonesian subpopulation

Background: Class II malocclusion is one of the main orthodontic issues for patients in seeking treatment. The prevalence of class II malocclusion varies in different populations. Variation in skeletal profile is mainly controlled internally by a regulatory gene. Runt-related transcription factor-2 (Runx2) plays a role in osteoblast differentiation and is highly expressed during development. Purpose: This study aimed to evaluate the relation of regulatory gene variation in the Runx2 promoter with class II malocclusion. Methods: DNA samples were acquired from 95 orthodontic patients in Jakarta, Indonesia, who were divided into two groups: class I skeletal malocclusion (control group) and class II malocclusion. A single nucleotide polymorphism was investigated using the polymerase chain reaction and restriction fragment length polymorphism techniques. The distribution of alleles was assessed using the Hardy-Weinberg test. The relationship between polymorphism and skeletal variation was assessed with the Chi-Square test and logistic regression. Results: The frequency distributions of genotypes and alleles were tested for Hardy-Weinberg equilibrium and found to be slightly deviated. There was an equal distribution of G and T alleles throughout class II and class I skeletal malocclusions and the Chi-Square test showed that this relationship was not significant (p=0.5). Conclusion: Runx2 rs59983488 polymorphism was found in the Indonesian subpopulation; however, an association between Runx2 rs59983488 polymorphism and class II skeletal malocclusion was not found.

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Relationship between skeletal malocclusion and dental anomalies in Nepalese population

Orthodontic Journal of Nepal ◽

10.3126/ojn.v9i1.25684 ◽

2019 ◽

Vol 9 (1) ◽

pp. 15-18

Author(s):

Bashu Dev Pant ◽

Anjana Rajbhandari ◽

Resina Pradhan ◽

Manju Bajracharya

Keyword(s):

Third Molar ◽

Class Ii ◽

Class I ◽

Class Ii Malocclusion ◽

Class Iii ◽

Dental Anomalies ◽

Chi Square ◽

Skeletal Class ◽

Skeletal Malocclusion ◽

Third Molar Agenesis

Introduction: Teeth eruption is important for the development of alveolar process which increases vertical height of the face and third molar is the last tooth to erupt in the oral cavity after birth. The aim of this study was to determine relationship between skeletal malocclusion and dental anomalies in Nepalese population. Materials & Method: A sample of 170 patients with agenesis of at least one third molar was divided into four groups according to the third-molar agenesis pattern. Panoramic radiographs, lateral cephalograph and cast models were used to determine the skeletal malocclusion and associated dental anomalies. The Pearson chi-square test was used for stastical analysis. Result: Among 170 patients more than half of the patients were female with the average age being 18.15 ± 3.64 years. Majority of the patients had Class I skeletal malocclusion followed by Class II and III but on group wise comparison of patients with different skeletal patterns Class I skeletal malocclusion had highest prevalence of dental anomalies followed by Class III and Class II malocclusion. Conclusion: Prevalence of third-molar agenesis was more in skeletal class I malocclusion followed by class II and III but skeletal Class I malocclusions had more dental anomalies followed by class III and class II malocclusion.

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Comparative cephalometric study of Class II malocclusion treatment with Pendulum and Jones jig appliances followed by fixed corrective orthodontics

Dental Press Journal of Orthodontics ◽

10.1590/s2176-94512013000600010 ◽

2013 ◽

Vol 18 (6) ◽

pp. 58-64 ◽

Cited By ~ 6

Author(s):

Mayara Paim Patel ◽

José Fernando Castanha Henriques ◽

Renato Rodrigues de Almeida ◽

Arnaldo Pinzan ◽

Guilherme Janson ◽

...

Keyword(s):

Class Ii ◽

Control Group ◽

Class Ii Malocclusion ◽

Chi Square ◽

Chi Square Test ◽

Young Subjects ◽

Group 2 ◽

And Gender ◽

The One ◽

Cephalometric Study

OBJECTIVE: The purpose of this study was to cephalometrically compare the skeletal and dentoalveolar effects in the treatment of Class II malocclusion with Pendulum and Jones jig appliances, followed by fixed corrective orthodontics, and to compare such effects to a control group. METHODS: The sample was divided into three groups. Group 1: 18 patients treated with Pendulum, Group 2: 25 patients treated with Jones jig, and Group 3: 19 young subjects with untreated Class II malocclusions and initial mean age of 12.88 years. The chi-square test was applied to assess severity and gender distribution. Groups 1 and 2 were compared to the control group by means of the one-way ANOVA and Tukey tests in order to differentiate treatment changes from those occurred by craniofacial growth. RESULTS: There were no significant changes among the three groups with regard to the components of the maxilla and the mandible, maxillomandibular relationship, cephalometric and tegumental pattern. Buccal tipping of mandibular incisors was significantly greater in the experimental groups and increased mesial angulation of the maxillary second molars was found in the Jones jig group. In the experimental groups, dental relationship, overbite and overjet were corrected. CONCLUSION: It can be stated that the distalization achieved its purpose of correcting the Class II.

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Facial Profile Shape, Malocclusion and Palatal Morphology in Malay Obstructive Sleep Apnea Patients

The Angle Orthodontist ◽

10.2319/011509-26.1 ◽

2010 ◽

Vol 80 (1) ◽

pp. 37-42 ◽

Cited By ~ 11

Author(s):

S. M. Banabilh ◽

A. R. Samsudin ◽

A. H. Suzina ◽

Sidek Dinsuhaimi

Keyword(s):

Obstructive Sleep Apnea ◽

Null Hypothesis ◽

Control Group ◽

Class Ii Malocclusion ◽

Chi Square ◽

Facial Profile ◽

Obstructive Sleep ◽

Significant Difference ◽

Chi Square Test ◽

The Mean

Abstract Objective: To test the null hypothesis that there is no difference in facial profile shape, malocclusion class, or palatal morphology in Malay adults with and without obstructive sleep apnea (OSA). Materials and Methods: Subjects were 120 adult Malays aged 18 to 65 years (mean ± standard deviation [SD], 33.2 ± 13.31) divided into two groups of 60. Both groups underwent clinical examination and limited channel polysomnography (PSG). The mean OSA and control values were subjected to t-test and the chi square test. Results: Physical examination showed that 61.7% of the OSA patients were obese, and 41.7% of those obese patients had severe OSA. The mean body mass index (BMI) was significantly greater for the OSA group (33.2 kg/m2 ± 6.5) than for the control group (22.7 kg/m2 ± 3.5; P < .001). The mean neck size and systolic blood pressure were greater for the OSA group (43.6 cm ± 6.02; 129.1 mm Hg ± 17.55) than for the control group (35.6 cm ± 3.52; 114.1 mm Hg ± 13.67; P < .001). Clinical examination showed that the most frequent findings among OSA groups when compared with the control group were convex profiles (71.7%), Class II malocclusion (51.7%), and V palatal shape (53.3%), respectively; the chi square test revealed a significant difference in terms of facial profile and malocclusion class (P < .05), but no significant difference in palatal shape was found. Conclusion: The null hypothesis is rejected. A convex facial profile and Class II malocclusion were significantly more common in the OSA group. The V palatal shape was a frequent finding in the OSA group.

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Relation between Angle Class II malocclusion and deleterious oral habits

Dental Press Journal of Orthodontics ◽

10.1590/s2176-94512012000600022 ◽

2012 ◽

Vol 17 (6) ◽

pp. 111-117

Author(s):

José Tarcísio Lima Ferreira ◽

Maria do Rosário Ferreira Lima ◽

Luciana Zappeloni Pizzolato

Keyword(s):

Class Ii ◽

Class Ii Malocclusion ◽

Class Iii ◽

Chi Square ◽

Significance Level ◽

Oral Habits ◽

Angle Class Ii ◽

Stomatognathic System ◽

Chi Square Test ◽

History Of

INTRODUCTION: Oral habits may interfere on the growth and development of the stomatognathic system and orofacial myofunctional conditions, producing changes in the position of teeth in their dental arches. OBJECTIVE: The purpose of this study was to verify the presence of deleterious oral habits in individuals with malocclusion and see if there is a predominance of Class II malocclusion in these individuals. METHODS: The records of 140 patients treated at the Clinic of Preventive Orthodontics FORP-USP who had already completed treatment were randomly selected and analyzed. Their ages ranged from 6 to 10 years and 11 months. Associations were made between the presence or absence of deleterious oral habits, type and number of habits found in each individual and the type of malocclusion according to Angle classification. The statistical analysis used was the Chi-square test with a significance level of 5%. History of deleterious oral habits was found in 67.1% of individuals. RESULTS: The Class I malocclusion was most frequent (82.9%), followed by Class II malocclusion (12.1%) and Class III (5%). CONCLUSION: There was a predominance of Class II malocclusion in individuals with a history of deleterious oral habits.

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Analysis of Patients with Skeletal Malocclusion Undergoing Orthognathic Surgery Along with Fixed Orthodontics in a Dental Hospital Setup

International Journal of Research in Pharmaceutical Sciences ◽

10.26452/ijrps.v11ispl3.2949 ◽

2020 ◽

Vol 11 (SPL3) ◽

pp. 385-391

Author(s):

Pooja Umaiyal M ◽

Saravana Dinesh S P ◽

Jaiganesh Ramamurthy

Keyword(s):

Orthognathic Surgery ◽

Class Ii ◽

P Value ◽

Class Iii ◽

Chi Square ◽

Fixed Appliance ◽

Skeletal Malocclusion ◽

Division 1 ◽

Dental Hospital ◽

Chi Square Test

Lately, people have become more conscious about their physical appearance. Orthodontic treatment has no doubt in providing a significant effect on facial aesthetics. Commonly treated dental and skeletal malocclusion includes class II and class III, skeletal malocclusions might need orthodontic fixed appliance, orthognathic surgery or a combination of both for its correction. The aim of this study is to analyse the prevalence percentage of patients with skeletal malocclusion undergoing orthognathic surgery along with fixed orthodontics. We reviewed and analysed the data of 86000 patients who visited a dental institutional hospital between June 2019 and March 2020. A total of 60 patients were chosen to be included in this retrospective study. They were diagnosed with either class II or class III malocclusions. Socio-demographic and clinical data of all the 60 patients were collected, such as age, gender, type of skeletal malocclusion, treatment suggested and treatment undergone were retrieved from the patient records provided by Saveetha Dental College and Hospitals. This data was tabulated in excel and analysed using SPSS software. Chi-Square test was performed, and the p-value was determined to evaluate the significance of the variables. Among the patients, 51.7% were males with the peak prevalence of reporting for skeletal malocclusion treatment at the age of 10-30 years (85%). Most predominant dental malocclusion being class II division 1 (38.3%) followed by class III(23.3%). Proclination (40%) and crowding (60%) were other common dental alignment issues in the maxillary and mandibular arches, respectively.

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Assessment of Efficacy of Novel Method of Quantifying and Grading Class II Malocclusion in Vidarbha Population

Journal of Pharmaceutical Research International ◽

10.9734/jpri/2021/v33i47a33008 ◽

2021 ◽

pp. 230-234

Author(s):

Niraj Nitin Tikar ◽

Amit Reche ◽

Vikrant Jadhav ◽

Priyanka Paul Madhu ◽

Kumar Gaurav Chhabra ◽

...

Keyword(s):

Treatment Planning ◽

Class Ii ◽

Patient Comfort ◽

Class Ii Malocclusion ◽

Proper Treatment ◽

Chi Square ◽

Chi Square Test ◽

Proper Diagnosis ◽

Dentofacial Orthopedics ◽

Relationship Of

Background: It is important to quantify class II malocclusion for proper diagnosis of the case and adjusted treatment will aid in successful correction of malocclusion. Hence, the study will aid for proper treatment planning by classifying class II malocclusion established on the amount of overjet, overbite, distance and relation of maxillary and mandibular first molar and the relationship of canine and molar. Objectives: To grade Class II malocclusion in form of overjet and overbite. Materials and Methods: Patients visiting Department of Orthodontics and Dentofacial Orthopedics, Sharad Pawar Dental College, Wardha, having class II malocclusion will be chosen. The chi square test, student's paired and unpaired t test, and descriptive and inferential statistics will be used in the statistical analysis. Expected Results: The outcome after conduction of the study is expected to have more patients with Type 1 overjet and Type B overbite kind of Class II malocclusion. Conclusion: The establishment of this new classification will aid in concise analysis and proper treatment planning of Class II malocclusion thereby enhancing the esthetics and functional stability for the patient comfort.

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Pattern of Malocclusion in Patients Seeking Orthodontic Treatment at Medical Colleges & Teaching Hospitals of Chitwan, Nepal

Orthodontic Journal of Nepal ◽

10.3126/ojn.v8i2.23069 ◽

2018 ◽

Vol 8 (2) ◽

pp. 41-44

Author(s):

Bashu Raj Pandey ◽

Shailendra Kumar Singh ◽

Rajan Singh ◽

Rajeev Mishra ◽

Srijana Mishra ◽

...

Keyword(s):

Orthodontic Treatment ◽

Class Ii ◽

Class I ◽

Teaching Hospitals ◽

Class Iii ◽

Chi Square ◽

Deep Bite ◽

Chi Square Test ◽

Orthodontic Patients ◽

Medical Colleges

Introduction: Various forms of malocclusion is most common dentofacial abnormality found in human population. People seek tteatment for such abnormalities based on the severity. The objective of this research is to evaluate Pattern of Malocclusion in Patients Seeking Orthodontic Treatment at Medical Colleges and Teaching Hospitals of Chitwan, Nepal. Materials & Method: Two hundred thirty nine pre-operative study casts of orthodontic patients aged from 12-50 years selected from 550 patient’s records of departments of orthodontics of Chitwan Medical Colleges and Colleges of Medical Sciences, Bharatpur of Chitwan. Standard protocol of Angle’s classification of malocclusion was used to classify malocclusion and its attributes were recorded. Pearson’s Chi square test was performed to justify the result. Result: The prevalence of malocclusion were 61.92% , 33.47% and 4.60% for Angle’s class I, Angle’s class II and Angle’s class III malocclusion respectively. Among various attributes of malocclusion, deep bite had highest frequency with 67.36% followed by overjet 58.99%, crowding 53.13% and spacing 35.98%, Anterior cross bite 11.71% reverse overjet 4.6%, posterior cross bite 1.2% and scissor bite 0.041%. Pearson Chi square test showed no relation among these attributes and sex and age at p < .05. Conclusion: Angle’s class I malocclusion is most prevalent followed by Angle’s class II and Angle’s class III.

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Class II Skeletal Malocclusion and Prevalence of Temporomandibular Disorders. An Epidemiological Pilot Study on Growing Subjects

Journal of Functional Morphology and Kinesiology ◽

10.3390/jfmk6030063 ◽

2021 ◽

Vol 6 (3) ◽

pp. 63

Author(s):

Grazia Fichera ◽

Vincenzo Ronsivalle ◽

Simona Santonocito ◽

Khaled S. Aboulazm ◽

Gaetano Isola ◽

...

Keyword(s):

Temporomandibular Disorders ◽

Class Ii ◽

Class I ◽

Class Ii Malocclusion ◽

Class Iii ◽

Predisposing Factor ◽

Skeletal Malocclusion ◽

Skeletal Class Ii ◽

Group A ◽

Male Subjects

The purpose of our work is to evaluate the correlation between skeletal Class II malocclusion and temporomandibular disorders, by assessing potential different frequency scores compared with Class I and Class III skeletal malocclusion, and to evaluate associated etiological and risk factors. Fifty-five subjects were examined, 35 females and 20 males, with a mean age of 18 ± 1.3 years, divided into two groups: those with TMD and those without TMD, and prevalence was evaluated in the two groups of Class II subjects. Symptoms and more frequent signs were also examined in the TMD group. Regarding Group A (subjects with the presence of TMD), we found that 48% have a Class II, 16% have Class I, and 28% have Class III. In the totality of the group A sample, only 8% were male subjects. In Group B (subjects without TMD), we found that 40% were females, with 26.7% in Class I, 10% in Class II, and 3.3% in Class III; the male subjects in this group (60%) were distributed with 33.3% in Class I, 16.7% in Class II, and 10% in Class III. Class II malocclusion is not a causal factor of TMD but may be considered a predisposing factor.

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Prevalence of Malocclusion in Western Nepal

Orthodontic Journal of Nepal ◽

10.3126/ojn.v5i2.15215 ◽

2015 ◽

Vol 5 (2) ◽

pp. 6-8 ◽

Cited By ~ 1

Author(s):

Prakash Baral

Keyword(s):

Class Ii ◽

Open Bite ◽

Class I ◽

Class Iii ◽

Chi Square ◽

Gender Dimorphism ◽

Deep Bite ◽

Gender Variation ◽

Chi Square Test ◽

Mandibular Teeth

Introduction: Malocclusion is the improper relationship of maxillary and mandibular teeth. The prevalence of malocclusion varies in different populations of the world.Objective: To study the prevalence of malocclusion in western part of Nepal and to evaluate the gender variation in occurrence of malocclusion.Materials & Method: A total of 1284 subjects were studied. Out of them 656 were male and 628 were female. Intra-oral examination was carried out to assess occlusal types of Class I, II, III according to Angle’s classification of malocclusion, and various occlusal characteristics like crowding, spacing, cross-bite, open-bite and deep bite were recorded. Gender variation in malocclusion characteristics were tested using chi-square test (p<0.05).Result: The present study showed that Class I occlusion type with malocclusion was more prevalent than Class II and Class III malocclusions. Class I was seen in 71.5% , Class II div 1 in 20.7%, Class II div 2 in 3.9% cases and Class III in 4.1% cases. Among the occlusal characteristics; crowding (61.3%), deep bite (29.5%) and spacing (10.5%) were most prevalent.Conclusion: Class I malocclusion was most prevalent type of malocclusion in western Nepalese subjects. There was no significant gender dimorphism between male and female in prevalence of various malocclusion characteristics.

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SKELETAL AND DENTAL CHANGES INDUCED BY BIONATOR IN EARLY TREATMENT OF CLASS II

Acta Scientiarum Health Sciences ◽

10.4025/actascihealthsci.v38i2.28763 ◽

2016 ◽

Vol 38 (2) ◽

pp. 205

Author(s):

Dirceu Barnabé Raveli ◽

João Paulo Schwartz ◽

Taísa Boamorte Raveli ◽

Ary Dos Santos Pinto ◽

Bryan Tompson

Keyword(s):

Early Treatment ◽

Treatment Time ◽

Class Ii ◽

Treated Group ◽

Control Group ◽

Differential Growth ◽

Chi Square ◽

Significance Level ◽

Chi Square Test ◽

Student’S T

The purpose was to investigate the amount of skeletal and dentoalveolar changes after early treatment of Class II, Division 1 malocclusion with bionator appliance in prepubertal growing patients. Forty Class II patients were divided in two groups. Treated group consisted of 20 subjects treated consecutively with bionator. Mean age at the start of treatment (T0) was 9.1 years, while it was 10.6 years at the end of treatment (T1). Mean treatment time was 17.7 months. Pretreatment and post-treatment cephalometric records of treated group were evaluated and compared with a control group consisted of 20 patients with untreated Class II malocclusion. Intergroup comparisons were performed using Student’s t-tests and chi-square test with Yates’ correction at a significance level of 5 per cent. Bionator appliance was effective in generating differential growth between the jaws. Cephalometric skeletal measurements ANB, WITS, Lafh, Co-A and dental L6-Mp, U1.Pp, IsIi, OB, OJ showed statistically significantly different from the control. Bionator induced more dentoalveolar changes than skeletal during treatment in prepubertal stage.

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