DIABETES MELLITUS: ROLE OF FREE RADICALS AND OXIDATIVE STRESS

Author(s):  
Md. Zishan
2019 ◽  
Vol 2 (4) ◽  
pp. 382-392
Author(s):  
Mohammad Mahdi Sabahi ◽  
Sara Ami Ahmadi ◽  
Reza Mahjub ◽  
Akram Ranjbar

Diabetes mellitus is one of the most common chronic medical conditions in the world. Increasing evidence suggests that chronic hyperglycemia can cause excessive production of free radicals, particularly reactive oxygen species (ROS). Free radicals play important roles in tissue damage in diabetes. The relationship between exposure to nanoparticles (NPs) and diabetes has been reported in many previous studies. Evaluation of the potential benefits and toxic effects of NPs on diabetic disorders is of importance. This review highlights studies on the relationship between NPs and oxidative stress (OS) as well as the possible mechanisms in diabetic animal models and humans.


2016 ◽  
Author(s):  
Talat Saatov ◽  
Zafar Ibragimov ◽  
Sanobarxon Irgasheva ◽  
Elvira Ibragimova ◽  
Bakhodir Zainutdinov ◽  
...  

HORMONES ◽  
2020 ◽  
Vol 19 (3) ◽  
pp. 433-438
Author(s):  
Eirini Kostopoulou ◽  
Ioulia Livada ◽  
Ioanna Partsalaki ◽  
Fotini Lamari ◽  
Spyros Skiadopoulos ◽  
...  

2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Vanessa Palermo ◽  
Fulvio Mattivi ◽  
Romano Silvestri ◽  
Giuseppe La Regina ◽  
Claudio Falcone ◽  
...  

In recent years, epidemiological and biochemical studies have shown that eating apples is associated with reduction of occurrence of cancer, degenerative, and cardiovascular diseases. This association is often attributed to the presence of antioxidants such as ascorbic acid (vitamin C) and polyphenols. The substances that hinder the presence of free radicals are also able to protect cells from aging. In our laboratory we used yeast, a unicellular eukaryotic organism, to determinein vivoefficacy of entire apples and their components, such as flesh, skin and polyphenolic fraction, to influence aging and oxidative stress. Our results indicate that all the apple components increase lifespan, with the best result given by the whole fruit, indicating a cooperative role of all apple components.


Sign in / Sign up

Export Citation Format

Share Document