scholarly journals Analytical Expression of Concentrations and Current in Enzyme-Based Two-Compartment Model of Amperometric Biosensors for Steady-State Condition

2022 ◽  
pp. ArticleID:220238
Author(s):  
S Thamizh Suganya ◽  
Keyword(s):  
Steady State ◽  
Compartment Model ◽  
State Condition ◽  
Amperometric Biosensors ◽  
Steady State Condition ◽  
Analytical Expression ◽  
Two Compartment Model

Continuous determination of the volume of a space in a non steady state condition

1974 ◽  
Vol 36 (1) ◽  
pp. 59-66
Author(s):  
Oscar A. Gómez-Poviña ◽  
Carmen Sainz de Calatroni ◽  
Susana Orden de Puhl ◽  
Mariano J. Guerrero
Keyword(s):  
Steady State ◽  
State Condition ◽  
Steady State Condition ◽  
Continuous Determination

An Approach for Snaky Well Productivity under Steady-State Condition

2006 ◽  
Author(s):  
Zhilin Qi ◽  
Zhimin Du ◽  
Baosheng Liang ◽  
Yong Tang ◽  
Shouping Wang ◽  
...  
Keyword(s):  
Steady State ◽  
State Condition ◽  
Well Productivity ◽  
Steady State Condition

VIBRATIONS OF THE CLOSED FRAME STRUCTURES IN A STEADY-STATE CONDITION

Akustika ◽  
2021 ◽  
pp. 4-7
Author(s):  
Veronika Krutova ◽  
Besarion Meskhi
Keyword(s):  
Steady State ◽  
State Condition ◽  
Frame Structures ◽  
Steady State Condition ◽  
Load Bearing ◽  
Gantry Cranes

The load-bearing frames of the technological machinery of various functional purposes, such as bridge and gantry cranes, locomotives, motor locomotives, etc., are energetically closed rod systems [1-10].

Modelling And Simulation of Topical Drug Diffusion in The Dermal Layer of Human Body

2021 ◽  
Vol 86 (2) ◽  
pp. 39-49
Author(s):  
Sudi Mungkasi
Keyword(s):  
Steady State ◽  
Human Body ◽  
Diffusion Problem ◽  
State Condition ◽  
Unsteady State ◽  
Steady State Condition ◽  
Drug Diffusion ◽  
Dermal Layer ◽  
Drug Concentrations ◽  
Proposed Model

We consider the problem of drug diffusion in the dermal layer of human body. Two existing mathematical models of the drug diffusion problem are recalled. We obtain that the existing models lead to inconsistent equations for the steady state condition. We also obtain that solutions to the existing models are unrealistic for some cases of the unsteady state condition, because negative drug concentrations occur due to the inappropriate assumption of the model. Therefore, in this paper, we propose a modified mathematical model, so that the model is consistent, and the solution is nonnegative for both steady and unsteady state conditions of the drug diffusion problem in the dermal layer of human body. For the steady state condition, the exact solution to the proposed model is given. For unsteady state condition, we use a finite difference method for solving the models numerically, where the discretisation is centred in space and forward in time. Simulation results confirm that our proposed model and method preserve the non-negativity of the solution to the problem, so the solution is more realistic than that of the old model.

Estimation of the rate of appearance in the non-steady state with a two-compartment model

1992 ◽  
Vol 263 (2) ◽  
pp. E400-E415 ◽  
Author(s):  
A. Mari
Keyword(s):  
Steady State ◽  
Time Course ◽  
Specific Activity ◽  
Glucose Production ◽  
Compartment Model ◽  
New Method ◽  
Two Compartment Model ◽  
Glucose Clamp Technique ◽  
Glucose Output ◽  
The Relationship

A simple tracer-based method for calculating the rate of appearance of endogenous substances in the non-steady state, free from the inconsistencies of Steele's equation, is still lacking. This paper presents a method based on a two-compartment model by which the rate of appearance can be calculated with only a modest increase in complexity over Steele's approach. An equation is developed where the rate of appearance is expressed as a sum of three terms: a steady-state term, a term for the first compartment, and a term for the second compartment. The formula employs three parameters and makes the relationship between rate of appearance and specific activity changes explicit. An equation is also provided for estimating the error of the method in each individual run. The algorithm can be implemented with a spreadsheet on a personal computer. Simulated and experimental data obtained by the hyperinsulinemic euglycemic glucose clamp technique were used as a test. The accuracy with which the time course of glucose production could be reconstructed was clearly better than that using Steele's equation. Marked negative values for endogenous glucose output were calculated with Steele's equation but not with the new method. The characteristics of generality, simplicity, and accuracy and the availability of an error estimate make this new method suitable for routine application to non-steady-state tracer analysis.

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