scholarly journals Modern Concepts of Fibromuscular Dysplasia of the Coronary Arteries

2019 ◽  
Vol 15 (3) ◽  
pp. 431-438
Author(s):  
E. L. Trisvetova
Keyword(s):  
Acute Coronary Syndrome ◽  
Coronary Arteries ◽  
Fibromuscular Dysplasia ◽  
Clinical Manifestations ◽  
Intramural Hematoma ◽  
Vascular Wall ◽  
Vascular Lesion ◽  
Diagnostic Methods ◽  
International Consensus ◽  
Coronary Syndrome

Fibromuscular dysplasia of the coronary arteries is a rare non-atherosclerotic and non-inflammatory vascular lesion that is asymptomatic until serious complications develop: stenosis, dissection, rupture, sudden cardiac death. Since there are no long-term numerous clinical observations of patients with fibromuscular dysplasia of the coronary arteries, recommendations have not been developed for diagnosing and treating the disease, which often manifests with acute coronary syndrome. In 2014, the European Consensus was published, and in 2019, the first international consensus document on the diagnosis and treatment of fibromuscular dysplasia with lesions of vessels from different regions (renal, cerebrovascular, coronary, and others). The documents state that the development of fibromuscular dysplasia of the coronary arteries considers the participation of the PHACTR1 gene mutation and the transcriptional activity of the EDN1 gene, smoking, prolonged exertion of the vascular wall, and possibly female sex hormones. In the case of acute coronary syndrome, the most informative diagnostic method is computed tomography with angiography, which reveals a smooth narrowing of the lumen in the middle or distal section in the epicardial artery, often due to intramural hematoma, and also finds dissection, spasm, and tortuous vessel. Additional diagnostic methods ‒ intravascular ultrasound and optical coherence tomography allow differentiation of fibromuscular dysplasia with atherosclerosis of the coronary artery, vasculitis, and other diseases. The choice of treatment tactics for fibromuscular dysplasia of the coronary arteries depends on the severity of the clinical manifestations ‒ conservative medical treatment and interventional methods are used.

scholarly journals DIAGNOSIS OF ACUTE CORONARY SYNDROME IN PATIENTS WITH CONGENITAL ANOMALY OF CORONARY ARTERIES

2021 ◽  
Vol 21 (2) ◽  
pp. 225-228
Author(s):  
O.A. Shaposhnyk ◽  
T.I. Shevchenko ◽  
S.I. Sorokina ◽  
I. P. Kudrya ◽  
N.G. Tretiak
Keyword(s):  
Acute Coronary Syndrome ◽  
Coronary Artery ◽  
Coronary Angiography ◽  
Coronary Arteries ◽  
Relevant Literature ◽  
Clinical Manifestations ◽  
Diagnostic Methods ◽  
Coronary Artery Anomalies ◽  
Coronary Syndrome ◽  
Cardiac Symptoms

The article highlights the issues of terminology, prevalence, diagnosis, clinical manifestations, and the therapy of patients with congenital anomalies of the coronary arteries. Special attention is paid to the current state of the problem of congenital coronary artery anomalies and their in coverage in the relevant literature. Anomalies of the coronary arteries can cause the development of acute coronary syndrome and then lead to disability of the employable population. The aim of thus study was to analyze and compare clinical manifestations in coronary artery anomalies and angiographic changes of coronary arteries in order to improve the diagnosis of acute forms of coronary heart disease, and namely, acute coronary syndrome. We underscored the clinical significance of invasive diagnosis of coronary artery abnormalities using coronary angiography. We represented detailed analysis of the clinical case of an atypical course of acute coronary syndrome, accompanied by cardiac symptoms supported with changes on the electrocardiogram. Coronary angiography revealed a myocardial muscle bridge, which compressed the trunk of the left coronary artery during the systole, thus significantly reducing coronary artery diameter and provoking an attack of chest pain. Modern diagnostic methods enable to assess not only the condition of the coronary arteries, but also the features of their topography, and, in particular, in the myocardium.

A Young Woman Case of Acute Coronary Syndrome Caused by Extensive Coronary Intramural Hematoma with Hyperthyroidism

2012 ◽  
Vol 4 (3) ◽  
pp. 200-207
Author(s):  
Toshimitsu Takagi ◽  
Yuki Horita ◽  
Naoto Tama ◽  
Hidenobu Terai ◽  
Isao Inoki ◽  
...  
Keyword(s):  
Acute Coronary Syndrome ◽  
Young Woman ◽  
Intramural Hematoma ◽  
Coronary Syndrome

scholarly journals Acute Coronary Syndrome With Normal Coronary Arteries: a Case of Spontaneous Spasm Lysis

2018 ◽  
Vol 72 (2) ◽  
pp. 154 ◽  
Author(s):  
Vogiatzis Ioannis ◽  
Koutsambasopoulos Konstantinos ◽  
Samaras Antonios ◽  
Bostanitis Ioannis
Keyword(s):  
Acute Coronary Syndrome ◽  
Coronary Arteries ◽  
Normal Coronary Arteries ◽  
Coronary Syndrome

scholarly journals ANALYSIS OF DATA FROM MINOCA PATIENTS BASED ON COMPARISON OF TOTAL REGISTER OF ACUTE CORONARY SYNDROME IN THE KRASNODAR REGION WITH FOREIGN REGISTERS

2019 ◽  
Vol 33 (4) ◽  
pp. 38-43
Author(s):  
S. V. Kruchinova ◽  
E. D. Kosmacheva ◽  
S. A. Raff ◽  
V. A. Porkhanov
Keyword(s):  
Myocardial Infarction ◽  
Acute Coronary Syndrome ◽  
Comparative Analysis ◽  
Coronary Arteries ◽  
Krasnodar Krai ◽  
Coronary Syndrome ◽  
Krasnodar Region

The review presents a comparative analysis of data from patients with myocardial infarction with non-obstructive coronary arteries. Data were obtained from the total register of acute coronary syndrome in the Krasnodar Krai and were compared with data of foreign registers.

scholarly journals Heat Therapy to Reduce Chest-Pain Among Patients with Acute Coronary Syndromes (ACS): A Literature Review

2020 ◽  
Vol 1 (2) ◽  
Author(s):  
Aan Nur'aeni ◽  
Yanny Trisyani ◽  
Donny Nurhamsyah ◽  
Oman Hendi ◽  
Rahmalia Amni ◽  
...  
Keyword(s):  
Acute Coronary Syndrome ◽  
Chest Pain ◽  
Literature Review ◽  
Meta Analysis ◽  
Clinical Manifestations ◽  
Inclusion Criteria ◽  
Coronary Syndrome ◽  
Heat Therapy ◽  
Nonpharmacological Intervention ◽  
Analgesic Opioids

The main clinical manifestations of patients with Acute Coronary Syndrome (ACS) during the acute period is chest pain. Handling complaints of pain patients with ACS definitively done with medication; however, it is possible to do additional nonpharmacological therapies to optimize the results. Nonpharmacological treatment can be performed in various ways, one of them with heat therapy. This literature review aimed to determine the use of heat therapy as an additional nonpharmacological intervention in reducing the intensity of chest pain in patients with ACS. Four electronic databases were used to carry out systematic searches on articles, namely Proquest, Science Direct, Pubmed, and CINAHL-Ebsco. The combination of keywords was "heat therapy" AND "chest pain" AND "acute coronary syndrome" NOT "Literature review" OR "Literature review" OR "Overview" OR "Systematic Review" OR "Meta-analysis." The inclusion criteria used were experimental study articles, peer-reviewed articles, and research articles written in English and performed in the period between 2014-2019. The search results obtained three articles that met the inclusion criteria and analyzed. The results of the study found that heat therapy effective in reducing the intensity of chest pain, the use of analgesic opioids, and improving the patient's hemodynamics. In conclusion, the therapy can be considered used as adjunctive therapy to reduce chest pain in patients with ACS with certain criteria. In addition, further research is also needed to see the effectiveness of this therapy if it is implemented with more frequent frequencies and compare its effectiveness in reducing chest pain if the application is given to the anterior or posterior of the chest.

scholarly journals Association of serum cystatin C levels with acute coronary syndrome in patients of advanced age

2019 ◽  
Vol 47 (5) ◽  
pp. 1987-1997 ◽  
Author(s):  
Qingyu Huang ◽  
Wei Shen ◽  
Jian Li ◽  
Xinping Luo ◽  
Haiming Shi ◽  
...  
Keyword(s):  
Acute Coronary Syndrome ◽  
Glomerular Filtration Rate ◽  
Glomerular Filtration ◽  
Coronary Arteries ◽  
Filtration Rate ◽  
Estimated Glomerular Filtration Rate ◽  
Advanced Age ◽  
Serum Cystatin C ◽  
Serum Cystatin ◽  
Coronary Syndrome

Objective This study was performed to investigate the relationship between the serum cystatin C (Cys C) level and acute coronary syndrome (ACS) in patients of advanced age. Methods The study included 184 patients with ACS and 46 healthy control subjects. Statistical analysis was performed using SPSS version 14.0 (SPSS Inc., Chicago, IL, USA). Results The serum Cys C level was significantly higher in patients with than without ACS (1.24 ± 0.30 vs. 1.42 ± 0.46 mg/L, respectively). Patients with more stenotic coronary arteries were significantly more likely to have higher median serum Cys C and creatinine levels and a lower estimated glomerular filtration rate. The multivariate logistic regression analysis demonstrated that the serum Cys C level was independently associated with the presence of ACS and the quantity of stenotic coronary arteries after adjustment for confounding factors. Additionally, the serum Cys C level was positively correlated with age, the creatinine level, and the N-terminal pro-B-type natriuretic peptide level in all patients but was negatively correlated with the estimated glomerular filtration rate. Conclusion A high serum Cys C level was independently associated with ACS and the quantity of stenotic coronary arteries in patients of advanced age regardless of renal function.

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