scholarly journals Metanephric adenoma: association between the imaging features of contrast-enhanced ultrasound and clinicopathological characteristics

Gland Surgery ◽  
2021 ◽  
Vol 10 (8) ◽  
pp. 2490-2499
Author(s):  
Dongmei Zhu ◽  
Lin Zhu ◽  
Ji Wu ◽  
Linghu Wu ◽  
Jian Li ◽  
...  
Keyword(s):  
Clinicopathological Characteristics ◽  
Imaging Features ◽  
Contrast Enhanced Ultrasound ◽  
Metanephric Adenoma ◽  
Contrast Enhanced

scholarly journals Imaging features of hepatic angiomyolipomas on real-time contrast-enhanced ultrasound

2010 ◽  
Vol 83 (989) ◽  
pp. 411-418 ◽  
Author(s):  
Z Wang ◽  
H-X Xu ◽  
X-Y Xie ◽  
X-H Xie ◽  
M Kuang ◽  
...  
Keyword(s):  
Real Time ◽  
Imaging Features ◽  
Contrast Enhanced Ultrasound ◽  
Contrast Enhanced

scholarly journals Contrast-Enhanced Ultrasound in the Differential Diagnosis of Primary Thyroid Lymphoma and Nodular Hashimoto’s Thyroiditis in a Background of Heterogeneous Parenchyma

2021 ◽  
Vol 10 ◽  
Author(s):  
Lulu Yang ◽  
Haina Zhao ◽  
Yushuang He ◽  
Xianglan Zhu ◽  
Can Yue ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Hashimoto’S Thyroiditis ◽  
Diagnostic Performance ◽  
Roc Curves ◽  
Hashimoto's Thyroiditis ◽  
Imaging Features ◽  
Contrast Enhanced Ultrasound ◽  
Thyroid Lymphoma ◽  
Contrast Enhanced ◽  
Primary Thyroid Lymphoma

ObjectiveTo investigate the diagnostic performance of contrast-enhanced ultrasound (CEUS) in the differentiation of primary thyroid lymphoma (PTL) and nodular Hashimoto’s thyroiditis (NHT) in patients with background of heterogeneous diffuse Hashimoto’s thyroiditis (HT).MethodsSixty HT patients with 64 thyroid nodules (31 PTL and 33 NHT) who had undergone CEUS examination were included in this study. With histopathological results as the reference, we evaluated the imaging features of each nodule on both conventional ultrasonography (US) and CEUS. Quantitative CEUS parameters including peak intensity (PI), time to peak (TTP), and area under the time–intensity curve (AUC) were gathered in the nodule and background parenchyma. The ratio indexes of theses parameters were calculated by the ratio of the lesion and the corresponding thyroid parenchyma. Logistic regression and receiver operating characteristic (ROC) curves analyses of valuable US indicators were further preformed to evaluate the diagnostic capability of CEUS in discrimination of PTL and NHT.ResultsAmong all the observed US imaging features and CEUS parameters, 10 indicators showed significant differences between PTL and NHT (all P < 0.05). All the significant indicators were ranked according to the odds ratios (ORs). Eight of them were CEUS associated including imaging features of enhancement pattern, degree, homogeneity, and quantification parameters of PI, AUC, ratios of PI, AUC, and TTP, while indicators on conventional US, including vascularity and size ranked the last two with ORs less than 3. The five single CEUS parameters showed good diagnostic performance in diagnosis of PTL with areas under ROC curves of 0.72–0.83 and accuracies of 70.3–75.0%. The combination of CEUS imaging features and the ratios of PI, AUC, and TTP demonstrated excellent diagnostic efficiency and achieved area under ROC curve of 0.92, which was significantly higher than any of the five single parameters (all P < 0.05), with a sensitivity of 83.9%, specificity of 87.9%, and accuracy of 85.9%.ConclusionsCEUS is an efficient diagnostic tool in the differential diagnosis of PTL and NHT for patients with diffuse HT. Conjoint analysis of CEUS imaging features and quantification parameters could improve the diagnostic values.

scholarly journals Contrast enhanced imaging features of liver metastasis from a meningeal solitary fibrous tumor: a case report

2018 ◽  
Vol 20 (3) ◽  
pp. 392 ◽  
Author(s):  
Beilei Lu ◽  
Qing Lu ◽  
Beijian Huang ◽  
Haixia Yuan ◽  
Chaolun Li
Keyword(s):  
Magnetic Resonance Imaging ◽  
Case Report ◽  
Liver Metastasis ◽  
Solitary Fibrous Tumor ◽  
Imaging Features ◽  
Contrast Enhanced Ultrasound ◽  
Resonance Imaging ◽  
Contrast Enhanced ◽  
Fibrous Tumor ◽  
Enhanced Imaging

A solitary fibrous tumor seldom originates from the meninges, and the accuracy of imaging modalities in the diagnosis of meningeal SFT metastasisis is perlexing. Contrast enhanced imaging modalities, such as contrast enhanced ultrasound and contrast enhanced magnetic resonance imaging are valuable in the differential diagnosis of hepatic neoplasms. This case report demonstrated the contrast enhanced ultrasound and enhanced magnetic resonance imaging features of one case of liver metastasis from a menigeal solitary fibrous tumor.

Conventional and contrast-enhanced ultrasound features in sclerosing adenosis and correlation with pathology

2020 ◽  
pp. 1-9
Author(s):  
Sihui Shao ◽  
Minghua Yao ◽  
Xin Li ◽  
Chunxiao Li ◽  
Jing Chen ◽  
...  
Keyword(s):  
Imaging Features ◽  
Contrast Enhanced Ultrasound ◽  
Exact Test ◽  
Contrast Enhanced ◽  
Chi Squared ◽  
Group 2 ◽  
Student’S T ◽  
Sensitivity Specificity ◽  
Sclerosing Adenosis ◽  
Group 1

OBJECTIVES: To evaluate the efficacy of conventional ultrasound (US) and contrast-enhanced ultrasound (CEUS) in differential diagnosis of sclerosing adenosis (SA) from malignance and investigate the correlated features with pathology. METHODS: We retrospectively enrolled 103 pathologically confirmed SA. All lesions were evaluated with conventional US while 31 lesions with CEUS. Lesions were divided into SA with or without benign lesions (Group 1, n = 81) and SA with malignancy (Group 2, n = 22). Performance of two methods were analyzed. The ultrasonographic characteristics were compared between two groups with Student’s t-test for measurement and chi-squared or Fisher’s exact test for count data. RESULTS: There were 22 lesions complicated with malignancy, and the mean age of Group 2 was higher than Group 1 (55.27 vs. 41.57, p <  0.001). The sensitivity, specificity and accuracy of conventional US and CEUS were 95.45%, 46.91%, 57.28% and 100%, 62.5%, 70.97%. Angularity (p <  0.001), spicules (p = 0.023), calcification (p = 0.026) and enlarged scope (p = 0.012) or crab claw-like enhancement (p = 0.008) in CEUS were more frequent detected in SA with malignancy. CONCLUSIONS: Though CEUS showed an improved accuracy, the performance of ultrasound in the diagnosis of SA was limited. Awareness and careful review of the histopathologically related imaging features can be helpful in the diagnosis of SA.

Value of contrast-enhanced malignancy imaging features in secondary grade diagnosis of BI-RADS-US type 4 breast lesions

2020 ◽  
pp. 030089162096571
Author(s):  
Junxi Gao ◽  
Wei Han ◽  
Di Li Mu La Ti Ai Si Mu Tu La ◽  
Xueqin Hou ◽  
Zhi Ming Li ◽  
...  
Keyword(s):  
Breast Imaging ◽  
Benign Lesion ◽  
Breast Lesions ◽  
Imaging Features ◽  
Contrast Enhanced Ultrasound ◽  
Contrast Enhanced ◽  
Peripheral Ring ◽  
Malignant Lesions ◽  
Type 3

Purpose: To explore the value of contrast-enhanced malignancy imaging features in secondary grade diagnosis of Breast Imaging Reporting and Data System for Ultrasonography (BI-RADS-US) type 4 breast lesions. Methods: After initial diagnosis by ultrasound, 124 BI-RADS-US type 4 patients with 130 lesions were examined by contrast-enhanced ultrasound (CEUS) and were classified again before surgery according to five contrast-enhanced malignancy imaging features: inhomogeneous enhancement, peripheral ring-like enhancement, expansive enhancement, internal filling defects, and surrounding radioactive convergence. Lesions with no contrast-enhanced features of malignancy were categorized as type 3; lesions with one, two, or three features of malignancy were categorized as type 4A, 4B, or 4C, respectively; and lesions with four or more indices of malignancy were categorized as type 5. The value of contrasted imaging features of malignancy in diagnosing BI-RADS-US type 4 breast lesions was analyzed. Results: The accuracy of CEUS diagnosis for type 3 lesions was 93.8% (46/49), 76.9% (10/13) for type 4A, 71.4% (5/7) for type 4B, 75.0% (9/12) for type 4C, and 93.8% (46/49) for type 5 lesions. The sensitivity of CEUS in diagnosing malignant lesions was 90.4%, specificity was 83.6%, and accuracy was 86.9%. CEUS decreased the benign lesion biopsy ratio to 68.5% (46/67) and increased the diagnosis ratio of malignant lesions to 73.0% (46/63). Conclusions: CEUS can further optimize the classification of BI-RADS-US type 4 breast lesions and may provide a better reference basis for clinical diagnosis and treatment of those breast lesions.

Analysis of contrast-enhanced ultrasound features of hepatocellular adenoma according to different pathological molecular classifications

2020 ◽  
Vol 76 (3) ◽  
pp. 391-403 ◽  
Author(s):  
Kailing Chen ◽  
Yi Dong ◽  
Weibin Zhang ◽  
Hong Han ◽  
Feng Mao ◽  
...  
Keyword(s):  
Late Phase ◽  
Hepatocellular Adenoma ◽  
World Health ◽  
Categorical Variables ◽  
Arterial Phase ◽  
Histopathological Diagnosis ◽  
Imaging Features ◽  
Continuous Variables ◽  
Contrast Enhanced Ultrasound ◽  
Contrast Enhanced

OBJECTIVE: To explore the specific contrast-enhanced ultrasound (CEUS) features of hepatocellular adenomas (HCA) according to their pathological molecular classifications. METHODS & MATERIALS: In this retrospective study, fifty-three histopathologically proved HCA lesions (mean size, 39.7±24.9 mm) were included. Final histopathological diagnosis of HCA lesions were identified by surgical resection (n = 51) or biopsy (n = 2) specimens. CEUS imaging features were compared among four subgroups according to World Health Organization (WHO) 2019 pathological molecular classifications standards. Analysis of variance (ANOVA) were used for statistical analysis of continuous variables. Fisher’s exact test were used for categorical variables. The sensitivity (SE), specificity (SP), and accuracy of CEUS feature in diagnosis of each HCA subtype were calculated and compared. RESULTS: Final histopathological diagnosis included HNF-1α inactivated HCAs (H-HCA, n = 12), β-catenin activated HCAs (B-HCA, n = 8), inflammatory HCAs (I-HCA, n = 31), and unclassified HCAs (U-HCA, n = 2). During arterial phase of CEUS, all HCAs were hyper-enhanced, 66.6% (8/12) of H-HCAs and 50% (4/8) of B-HCAs displayed complete hyperenhancement, whereas 58.0% (18/31) of I-HCAs showed centripetal filling hyperenhancement pattern (P = 0.016). Hyper-enhanced subcapsular arteries could be detected in 64.5% (20/31) I-HCAs during early arterial phase. During portal venous and late phase, sustained hyper- or iso-enhancement were observed in 91.7% (11/12) of H-HCAs, while most of I-HCAs (61.3%, 19/31) and B-HCAs (7/8, 87.5%) were hypo-enhanced (P = 0.000). Central unenhanced areas were most commonly observed in I-HCAs (29.0%, 9/31) (P = 0.034). CONCLUSION: Depending on its unique imaging features including enhancement filling pattern, hyper-enhanced subcapsular artery and presence of washout, CEUS might provide helpful diagnostic information for preoperative prediction of various HCA molecular subtypes.

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