scholarly journals Three-dimensional speckle-tracking echocardiography detects different patterns of right atrial dysfunction in selected disorders: a short summary from the MAGYAR-Path Study

2018 ◽  
Vol 8 (2) ◽  
pp. 182、-186 ◽  
Author(s):  
Attila Nemes ◽  
Péter Domsik ◽  
Anita Kalapos ◽  
Árpád Kormányos ◽  
Nóra Ambrus ◽  
...  
2020 ◽  
Vol 21 (Supplement_1) ◽  
Author(s):  
A Kormanyos ◽  
A Kalapos ◽  
P Domsik ◽  
N Gyenes ◽  
N Ambrus ◽  
...  

Abstract Introduction Acromegaly is a chronic, rare hormonal disease associated with major cardiovascular comorbidities. The disease, in the majority of the cases, is caused by a benign human growth hormone secreting adenoma. Cardiovascular involvement is especially common in acromegaly patients from the most common hypertension to cardiomyopathy. It was set out to quantify right atrial (RA) morphology and function in a group of acromegaly patients using three-dimensional (3D) speckle-tracking echocardiography (3DSTE). Methods The study comprised 30 patients from which 8 patients were excluded due to inadequate image quality. Mean age of the remaining acromegaly patients were 53.7 ± 14.5 years (7 males). Ten patients were in active phase, while 12 subjects had inactive acromegaly. In the control group 40 healthy adults were enrolled (mean age: 52.3 ± 8.2 years, 15 males). In each case, complete two-dimensional Doppler echocardiography was performed followed by 3DSTE. Results Maximum (54.5 ± 14.4 ml vs. 47.2 ± 11.6 ml, p <0.05) and minimum (35.5 ± 10.2 ml vs. 29.2 ± 9.1 ml, p <0.05) RA volumes and RA volume before atrial contraction (45.1 ± 11.1 ml vs. 38.2 ± 10.3 ml, p <0.05) were significantly higher in case of acromegaly compared to the healthy controls. Both global and mean segmental peak 3D strain (-11.94 ± 7.52% vs. -8.07 ± 5.03%, p <0.05 and -17.16 ± 6.13% vs. -13.78 ± 5.35%, p <0.05) were higher in the acromegaly group compared to the controls. At atrial contraction, mean segmental radial strain (-13.22 ± 6.45% vs. -9.74 ± 4.58%, p <0.05) was significantly higher and mean segmental 3D strain (-9.78 ± 5.44% vs. -13.78 ± 5.35%, p <0.05) was significantly lower in the acromegaly group compared to the controls. Between the active and inactive group of acromegaly patients, mean segmental longitudinal strain (28.17 ± 4.89% vs. 35.34 ± 9.75%, p <0.05) was significantly different. Numerous independent strain parameters had significant correlations with different hormonal variables in the active acromegaly group. These correlations were not present in the inactive acromegaly subgroup. Conclusion Acromegaly is associated with significant RA volumetric and functional abnormalities.


2020 ◽  
Vol 21 (Supplement_1) ◽  
Author(s):  
A Nemes ◽  
A Kormanyos ◽  
P Domsik ◽  
A Kalapos ◽  
N Ambrus ◽  
...  

Abstract Introduction The right atrium (RA) has several roles including a systolic reservoir, early diastolic conduit and late-diastolic booster pump functions. The present study aimed to assess normal reference values of three-dimensional speckle-tracking echocardiography (3DSTE)-derived RA volumetric data and volume-based functional properties (stroke volumes, SVs and emptying fractions, EFs) in healthy adult subjects. Methods 260 healthy adult subjects in sinus rhythm with complete clinical and demographic dataset have been included in the present study. However, due to inferior image quality 110 subjects have been excluded. The remaining population comprised 150 cases (31.0 ± 11.6 years, 79 males). Complete two-dimensional Doppler echocardiography and 3DSTE have been performed in all subjects. Results While systolic maximum RA volume did not change over age decades, early and late-diastolic RA pre-atrial contraction volume and minimum RA volume increased over time. Significantly larger values could be detected in more than 50 year-old healthy subjects as compared to younger subjects. Total atrial SV remained almost unchanged over age decades with a significant reduction in subjects aged >50 years. Passive atrial SV showed a continuous reduction over age decades and significant difference could be demonstrated between subjects aged 18-29 years and >50 years. Active atrial SV increased over age decades with a significant reduction in subjects aged >50 years. Total atrial EF did not show any changes over age decades, but a significant reduction could be demonstrated in cases aged >50 years. Passive atrial EF showed significant continuous reduction over age decades. Active atrial EF did not change in younger ages, it was the highest at ages 40-49 years with a significant impairment after 50 years. Females proved to have tendentiously higher RA volumes respecting the cardiac cycle regardless of age. No significant differences could be demonstrated between RA stroke volumes between genders except between 40-49 years when females had tendentiously higher values. RA emptying fractions were non-significantly, but tendentiously higher in females as compared to that of males regardless of age. Conclusions Normal reference values of 3DSTE-derived RA volumes and volume-based functional properties and their age- and gender dependency were defined in healthy adult subjects.


2015 ◽  
Vol 156 (24) ◽  
pp. 972-978 ◽  
Author(s):  
Györgyike Ágnes Piros ◽  
Péter Domsik ◽  
Anita Kalapos ◽  
Csaba Lengyel ◽  
Andrea Orosz ◽  
...  

Introduction: Heart cycle includes systole and diastole when heart chambers are characterized by a complex motion. Aim: The present study was designed to test whether relationships exist between three-dimensional speckle-tracking echocardiography-derived right atrial and routine two-dimensional echocardiography-derived left ventricular volumetric and functional parameters is healthy subjects. Method: The present study comprised 20 healthy volunteers. Complete two-dimensional echocardiography and three-dimensional speckle-tracking echocardiography were perfomed in all cases. Results: Left ventricular ejection fraction showed correlations with systolic and diastolic right atrial volumes and area strain characterzing atrial contraction in diastole. Right atrial volumes respecting cardiac cycle correlated only with left ventricular end-systolic diameter and volume, while similar relationships could not be confirmed with end-diastolic parameters. Conclusions: Relationships could be demonstrated between three-dimensional speckle-tracking echocardiography-derived right atrial and two-dimensional echocardiography-derived left ventricular volumetric and functional parameters in healthy subjects. Orv. Hetil., 2015, 156(24), 972–978.


2020 ◽  
Vol 21 (Supplement_1) ◽  
Author(s):  
A Nemes ◽  
A Kormanyos ◽  
P Domsik ◽  
A Kalapos ◽  
N Ambrus ◽  
...  

Abstract Introduction Classic echocardiographic methodologies offer limited opportunities in assessing right atrial (RA) morphology and function. Three-dimensional (3D) speckle-tracking echocardiography (3DSTE) is a novel imaging method with objective 3D capability in assessing volumetric and functional properties of heart chambers. Normal reference values of different 3DSTE-derived RA strains are not available, therefore the aim of this prospective study was to establish these parameters in healthy subjects. Methods The present study comprised 295 healthy volunteers, from which 110 were excluded due to inadequate image quality. The final population consisted of 185 healthy subjects in the present study (mean age: 32.1 ± 12.2 years, 89 males). Complete two-dimensional echocardiography and 3DSTE have been performed in all cases. Results While radial strain (RS) does not change significantly over the years in males, RS increases with age most significantly between 40-49 years, and it starts to decline at the age of 50 years in females. While females have higher circumferential strain (CS) and area strain (AS) values, RS decreases with age in both gender. While longitudinal strain (LS) remains almost unchanged in females until 40-49 years and declines above the age of 50 years in females, it decreases over decades in males. 3D strain (3DS) increases with ages in both gender, but almost doubles in females in older ages. While RS at atrial contraction does not change over decades in males, an obvious increase could be seen in females with a higher value between 40-49 years and a decline over 50 years. A decrease could be seen in CS at atrial contraction in males over decades, it is almost tripled in value between 40-49 years in females. Although LS at atrial contraction is higher in females, it decreases over decades in both genders. AS decreases over decades in males, while females have almost doubled AS values at the ages 40-49 years. 3DS is almost unchanged in males, while doubled in older ages in females. During evaluations, 110 subjects were excluded due to inferior image quality from the total of 295 enrolled subjects, therefore the overall feasibility of 3DSTE-derived RA quantification was 185 out of 295 (63% overall feasibility). Conclusion 3DSTE-derived RA normal reference values with age- and gender-dependency are demonstrated in a healthy population.


2012 ◽  
Vol 153 (40) ◽  
pp. 1570-1577 ◽  
Author(s):  
Attila Nemes ◽  
Anita Kalapos ◽  
Péter Domsik ◽  
Tamás Forster

Three-dimensional speckle-tracking echocardiography is a new cardiac imaging methodology, which allows three-dimensional non-invasive evaluation of the myocardial mechanics. The aim of this review is to present this new tool emphasizing its diagnostic potentials and demonstrating its limitations, as well. Orv. Hetil., 2012, 153, 1570–1577.


Choonpa Igaku ◽  
2014 ◽  
Vol 41 (2) ◽  
pp. 155-163
Author(s):  
Yoshihiro SEO ◽  
Tomoko ISHIZU ◽  
Akiko ATSUMI ◽  
Ryo KAWAMURA ◽  
Kazutaka AONUMA

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