scholarly journals Acute toxicity of silver nitrate to in vitro fertilization of the sand dollar, Echinarachnius parma

SURG Journal ◽  
2011 ◽  
Vol 4 (2) ◽  
pp. 71-74
Author(s):  
Olivia Marie Knight

Considered one of the most toxic heavy metals, interest in silver (both ionic and bound forms) has increased over the past few years due to the production of consumer goods containing Ag⁺-releasing nanoparticles. Investigation into acceptable environmental limits has generated a substantial amount of evidence that even at very low concentrations, silver exposure is detrimental to organism health. This study employed the echinoderm fertilization assay to evaluate acute silver toxicity to a marine invertebrate, Echinarachnius parma. Gametes were procured from E. parma and fertilization success under control conditions was compared to that at varying treatment concentrations of silver nitrate. Exposure to silver nitrate significantly decreased percent fertilization in all treatment concentrations. Remarkably, at concentrations as low as 10⁻⁹ M AgNO₃ percent fertilization decreased by 20-30% compared to the control. The results of this study are consistent with the existing literature, adding to the expanding collection of data that emphasizes the need for more stringent environmental silver regulation criteria in order to ensure the protection of aquatic ecosystems.

2016 ◽  
Vol 1 (1) ◽  
pp. 8-15 ◽  
Author(s):  
Prashant Purohit ◽  
◽  
Mike Savvas ◽  

Author(s):  
Georgina L. Jones ◽  
Victoria Lang ◽  
Nicky Hudson

AbstractThe year 2018 marked 40 years since the birth of Louise Brown, the first baby born as a result of pioneering in vitro fertilization (IVF) treatment. Since then, advances have seen a wide range of reproductive technologies emerge into clinical practice, including adjuvant treatments often referred to as IVF “add-ons.” However, these “optional extras” have faced growing criticism, especially when they have often come at additional financial cost to the patient and have little evidence supporting their efficacy to improve pregnancy or birth rates. Despite this, according to the latest national patient survey by the Human Fertilisation and Embryology Authority, three quarters of patients who had fertility treatment in the United Kingdom in the past two years had at least one type of treatment add-on highlighting the growing demand for these interventions. This article uses a psychosocial perspective to consider the motivations behind patient and clinician behavior along with the wider societal and economic factors that may be impacting upon the increase in the use of adjuvant treatments in fertility clinics more widely. It suggests the reasons fertility patients use unproven “optional extras” are complex, with interpersonal, psychological, and social factors intertwining to generate an increase in the use of IVF add-ons.


2021 ◽  
Vol 75 ◽  
pp. 304-317
Author(s):  
Joanna Talarczyk-Desole ◽  
Mirosław Andrusiewicz ◽  
Małgorzata Chmielewska ◽  
Anna Berger ◽  
Leszek Pawelczyk ◽  
...  

Background: Estrogen receptor 1 (ESR1) and 2 (ESR2) play an important role in regulating fertility in the human reproductive system. Polymorphisms of these receptor genes have been implicated in male infertility in both Chinese and Caucasian populations. However, studies have produced inconsistent results. Spermatozoa defects that result in conception deficiencies could be related to estrogens, their receptors, or genes involved in estrogen-related pathways. This study aims to explore the potential association between the ESR1 and the ESR2 polymorphisms in relation to semen parameters of Caucasian males as well as fertilization success. Materials/Methods: A total of 116 males were included in this study. Forty couples underwent conventional in vitro fertilization, while 76 couples were treated by intracytoplasmic sperm injection. Standard semen analyses were performed according to the World Health Organization criteria. Polymerase chain reaction and restriction fragment length polymorphisms were used to determine genotype and allele distributions. Results: A strong association between the ESR1 rs2234693 recognized by PvuII enzyme, genotype/allele distribution and fertilization success was shown. The T allele occurrence was significantly lower in the case of fertilization failure (p = 0.02). Additionally, the TT genotype was absent in the same group (p=0.02). In the case of the remaining analyzed polymorphisms, little to no interdependence of genotype/allele distribution and fertilization success was noted. Conclusions: Apart from ESR1 rs2234693, the study failed to demonstrate that fertilization success was associated with the selected polymorphisms. In most cases, we did not discover a relationship between both estrogen receptors polymorphisms and sperm function.


2009 ◽  
Vol 24 (S1) ◽  
pp. 1-1
Author(s):  
M.I. Ramos-Fuentes ◽  
M.J. Cardoso-Moreno ◽  
F.J. Vaz-Leal ◽  
N. Fernandez-Sanchez ◽  
L. Rodriguez-Santos ◽  
...  

Objective:In the past few decades, new and more efficient techniques to help solve fertility problems have become widely available throughout the developed world. The aim of this study was to determine whether there were differences on psychopathology factors between women who had conceived after in vitro fertilization (IVF) and women who had conceived naturally.Methods:The sample was composed of 41 pregnant women of whom 28 women had conceived through assisted reproductive technology (IVF) and 13 had conceived naturally. Women were evaluated by week 20 of pregnancy at the Infanta Cristina University Hospital Obstetrics and Gynecology Service, in Badajoz. Women consented to complete the Symptom Checklist-90-Revised (SCL-90-R).Results:IVF women were characterized by higher scores on Anxiety Scale (t = 3.90; p = 0.045) and lower scores on Hostility Scale (t = 4.35; p = 0.041) than women who had conceived naturally. There were no differences in the others scales.Conclusions:IVF women appear to present a temperamental profile characterized by a tendency to anxiety. Further research is needed to firstly, confirm these preliminary findings, and secondly, to longitudinally explore its impact on pregnancy outcome and mother-infant attachment.


2019 ◽  
Vol 133 (1) ◽  
pp. 127S-127S
Author(s):  
Christopher D. Beyer ◽  
Dmitry Gounko ◽  
Stephanie Pan ◽  
Lee Joseph ◽  
Alan Copperman ◽  
...  

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