SURGICAL TREATMENT OF BILATERAL NON TOXIC MULTINODULAR GOITRE: TOTAL VS SUB-TOTAL THYROIDECTOMY

2019 ◽  
Vol 13 (1) ◽  
pp. 13-18
Author(s):  
Atul M Bage ◽  
◽  
Lakshman Bhaskar M ◽  
Akshaya AC ◽  
◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Total Thyroidectomy ◽  
Multinodular Goitre

scholarly journals Surgical Treatment of Graves' Disease: Comparison between Total Thyroidectomy and Subtotal Thyroidectomy

2009 ◽  
Vol 77 (2) ◽  
pp. 82 ◽  
Author(s):  
Tae-Yon Sung ◽  
Yon Seon Kim ◽  
Sook Hyun Lee ◽  
Jong Ho Yoon ◽  
Suk-Joon Hong
Keyword(s):  
Surgical Treatment ◽  
Total Thyroidectomy ◽  
Subtotal Thyroidectomy ◽  
Graves Disease

scholarly journals Comparison of Complications between Total and Subtotal Thyroidectomy in Simple Multinodular Goitre

2018 ◽  
Vol 9 (2) ◽  
pp. 55-59
Author(s):  
Nadim Ahmed ◽  
Sami Ahmad ◽  
Farhad Uddin Ahmed ◽  
Muhammad Anwar Hossain ◽  
Krishna Pada Saha ◽  
...  
Keyword(s):  
Total Thyroidectomy ◽  
Subtotal Thyroidectomy ◽  
Fisher Exact Test ◽  
Multinodular Goitre ◽  
Chi Square ◽  
College Hospital ◽  
Nodular Goitre ◽  
Exact Test ◽  
Postoperative Haemorrhage ◽  
Significant Difference

Background: Multinodular goitre is one of the most common endocrine surgical problems. Because controversy still continues to surround the use of total thyroidectomy for management of simple nodular goitre, the present study was conducted to compare the complications between total and subtotal thyroidectomy for management of simple multinodular goitre.Materials & methods: The experimental study was conducted in the department of Surgery and ENT, Rajshahi Medical College Hospital over a period of 2 years from July 2011 to June 2013. Of the total 83 simple multinodular goitre patients – 38 were assigned to total and 45 to subtotal thyroidectomy groups. Student’s t-test was done to analyze the means of quantitative variables & Chi-square (X2) and Fisher Exact test was applied to analyze categorical variables.Results: Most (88.9%) of patients in subtotal thyroidectomy (STT) group and 86.8% in total thyroidectomy (TT) group did not receive any blood transfusion during operation. Only 1(2.2%) patient in STT group experienced significant intraoperative haemorrhage. All patients were successfully operated. However, few patients of either group experienced some complications. Tetany was developed in 7.89% patients of TT and 4.44% patients of STT group. The other complication was recurrent laryngeal nerve (RLN) palsy (5.3% in TT and 2.2% in STT groups). No case of postoperative haemorrhage (haematoma) or wound infection was occured in either group. In TT group 5 (13.16%) patients and in STT group 4 (8.89%) patients developed different complications with no significant difference between the groups (p=0.533). The mean postoperative hospital stay was higher in TT group than In STT group (6.21 ± 0.99 vs. 5.96 ± 0.79 days), though the difference is not statistically significant (p= 0.206).Conclusions: The study shows that total thyroidectomy can be performed without increasing risk of complications and is a better alternative to subtotal thyroidectomy for the treatment of simple multinodular goitre.J Shaheed Suhrawardy Med Coll, December 2017, Vol.9(2); 55-59

Impact of pre-operative serum 25-hydroxyvitamin D on post-operative serum calcium in patients undergoing total thyroidectomy for benign goitre: retrospective study of 246 patients

2017 ◽  
Vol 131 (10) ◽  
pp. 925-929 ◽  
Author(s):  
M Erlem ◽  
N Klopp-Dutote ◽  
A Biet-Hornstein ◽  
V Strunski ◽  
C Page
Keyword(s):  
Parathyroid Hormone ◽  
Retrospective Study ◽  
Total Thyroidectomy ◽  
Serum Calcium ◽  
Univariate Analysis ◽  
Multinodular Goitre ◽  
Serum Parathyroid Hormone ◽  
Single Centre ◽  
Hydroxyvitamin D ◽  
25 Hydroxyvitamin D

AbstractObjective:To determine whether pre-operative serum 25-hydroxyvitamin D has an impact on post-operative parathyroid hormone and serum calcium levels in patients undergoing total thyroidectomy for benign goitre.Methods:This single-centre, retrospective study comprised 246 unselected surgical patients who had undergone total thyroidectomy for bilateral, benign, multinodular goitre. The correlation between pre-operative serum 25-hydroxyvitamin D and post-operative serum parathyroid hormone and serum calcium was studied to determine whether low pre-operative serum 25-hydroxyvitamin D was predictive of post-operative hypocalcaemia.Results:Seventy-nine patients (32 per cent) had post-operative hypocalcaemia. Eighteen patients (7.32 per cent) experienced unintentional parathyroidectomy (1 parathyroid gland in 15 patients, 2 parathyroid glands in 3 patients). In univariate analysis, pre-operative serum 25-hydroxyvitamin D was not correlated with post-operative serum calcium (p = 0.69) or post-operative serum parathyroid hormone (p = 0.5804). Furthermore, in multivariate analysis, which took into account unintentional parathyroidectomy, no correlation was found (p = 0.33). Bilateral unintentional parathyroidectomy was statistically associated with post-operative hypocalcaemia (p = 0.032).Conclusion:Pre-operative serum 25-hydroxyvitamin D did not appear to have any impact on post-operative serum calcium in patients undergoing total thyroidectomy for benign goitre.

Total Thyroidectomy: The Procedure of Choice for Multinodular Goitre

2002 ◽  
Vol 168 (3) ◽  
pp. 196-196 ◽  
Author(s):  
M. Kaushal ◽  
G. Agarwal ◽  
S. K. Mishra
Keyword(s):  
Total Thyroidectomy ◽  
Multinodular Goitre

scholarly journals Association between multi nodular goitre and thyroid malignancy at a tertiary care centre

2021 ◽  
Vol 9 (1) ◽  
pp. 86
Author(s):  
Sreenidhi G. M. ◽  
Jyothi S.
Keyword(s):  
Total Thyroidectomy ◽  
Histopathological Examination ◽  
Tertiary Care ◽  
Histopathological Analysis ◽  
Multinodular Goitre ◽  
Thyroid Malignancy ◽  
Tertiary Care Centre ◽  
Cross Sectional ◽  
Nodular Goitre ◽  
Occult Malignancy

Background: Over the past few decades, the incidence of thyroid cancer has dramatically increased. Thyroid malignancy in multinodular goitre is considered to be high and these occult malignancies are detected only in post operative histopathological analysis. The study helps in finding association between multinodular goitre and thyroid malignancy. Objective was to find the association between multinodular goitre and thyroid malignancy in those who underwent total thyroidectomy.Methods: A cross sectional study conducted in department of general surgery, KIMS hospital, Bangalore. The 236 randomized cases of multinodular goitre who underwent total thyroidectomy were selected. Patients underwent thorough clinical examination pre operatively and were reassessed in post-operative period following surgery. Later, histopathology report on thyroidectomy specimen of the patients were obtained. This report was considered the gold standard for the diagnosis of thyroid malignancy.Results: Occult malignancies were commoner in middle aged females. Most of the patients in the study underwent total thyroidectomy. The prevalence of thyroid malignancy in our study was found to be 7.2%.  In the study, 17 incidental malignancies were papillary carcinomas. It revealed a highly significant relation between the lymphocytic thyroiditis and occult malignancy (p<0.0001)Conclusions: The prevalence of malignancy in multinodular goitre is 7.2%. The only variant of incidental malignancy detected in histopathological examination of excised thyroid was papillary carcinoma. There is a statistically significant association between presence of thyroiditis in preoperative FNA and presence of occult malignancy carcinoma.

scholarly journals Hemithyroidectomy for Thyroid Cancer: A Review

Medicina ◽  
2020 ◽  
Vol 56 (11) ◽  
pp. 586
Author(s):  
Noor Addasi ◽  
Abbey Fingeret ◽  
Whitney Goldner
Keyword(s):  
Thyroid Cancer ◽  
Surgical Treatment ◽  
Total Thyroidectomy ◽  
Low Risk ◽  
American Thyroid Association ◽  
Well Differentiated ◽  
Cancer Guidelines ◽  
Personalized Approach ◽  
Management Recommendations ◽  
Cancer Network

Thyroid cancer incidence is on the rise; however, fortunately, the death rate is stable. Most persons with well-differentiated thyroid cancer have a low risk of recurrence at the time of diagnosis and can expect a normal life expectancy. Over the last two decades, guidelines have recommended less aggressive therapy for low-risk cancer and a more personalized approach to treatment of thyroid cancer overall. The American Thyroid Association (ATA) and National Comprehensive Cancer Network (NCCN) thyroid cancer guidelines recommend hemithyroidectomy as an acceptable surgical treatment option for low-risk thyroid cancer. Given this change in treatment paradigms, an increasing number of people are undergoing hemithyroidectomy rather than total or near-total thyroidectomy as their primary surgical treatment of thyroid cancer. The postoperative follow-up of hemithyroidectomy patients differs from those who have undergone total or near-total thyroidectomy, and the long-term monitoring with imaging and biomarkers can also be different. This article reviews indications for hemithyroidectomy, as well as postoperative considerations and management recommendations for those who have undergone hemithyroidectomy.

Evaluation of Hypoparathyroidism following Total Thyroidectomy

2020 ◽  
Vol 26 (2) ◽  
pp. 116-120
Author(s):  
Md Nazmul Haque ◽  
Saif Rahman Khan ◽  
Moshammat Fatima Akhter ◽  
Mohammad Ashequr Rahman Bhuiyan ◽  
Mohammad Zakaria Sarker ◽  
...  
Keyword(s):  
Total Thyroidectomy ◽  
Neck Dissection ◽  
Serum Calcium ◽  
Calcium Supplementation ◽  
Follicular Carcinoma ◽  
Sampling Technique ◽  
Multinodular Goitre ◽  
Period 2 ◽  
Parathyroid Function ◽  
Malignant Lesions

The most common cause of hypoparathyroidism is damage to the glands during thyroid surgery. Parathyroid gland preservation during thyroidectomy is not only desirable, but essential for the effective management of surgical diseases of the thyroid gland Objective: To find out the incidence rate of hypoparathyroidism after total thyroidectomy. Methods: Study Period: 2 years from Jan 2017 to December 2018 Place of Study : National Institute of ENT, Tejgaon, Dhaka Study Design: Prospective Observational Study Sample size: 107 Sampling Technique: Convenient Sampling technique Results: Among the 107 cases 39 cases were malignant comprising 36.45% of the cases. toxic multinodular goitre were 6 cases among 107 cases (5.6%) and rest 62 cases were benign multinodular goitre with or without cystic change and follicular adenomas (57.94 %). 29 cases out of 39 malignant cases were papillary carcinoma of thyroid (74.36% of malignant lesions), 2 cases of medullary Ca thyroid (5.12 % of malignant lesions) rest 8 were follicular carcinoma (20.51% of malignant lesions). 26 out of 107 (24.30%) cases suffered from postoperative hypocalcaemic tetany within 1st-5th POD. Their parathyroid hormones were significantly reduced and serum calcium were also reduced and they required calcium supplementation. In 5 (4.67%) cases there was no sign and symptoms of tetany but their serum parathormone levels were little below normal level but serum calcium levels were normal and therefore no calcium supplementation were given. The rest 76 (71.03%) cases did not show any sign or symptoms of tetany and did not require calcium supplementation. Among the patients who suffered from tetany majority were cases of Carcinoma of thyroid (18 out of 26 patients of hypoparathyroidism) 69.23%, however lateral neck dissection did not seem to affect decline in parathyroid function as 10 out of 18 patients with thyroid malignancy who suffered from postoperative tetany undergone level II to level V neck dissection in addition to total thyroidectomy. Bangladesh J Otorhinolaryngol; October 2020; 26(2): 116-120

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