Physical activity types and risk of dementia in community-dwelling older people: the Three-City cohort.

Abstract Background Physical activity may decrease the risk of dementia; however, previous cohort studies seldom investigated the different types of physical activity and household activities. Our objective was to analyze the links between two physical activity types and dementia in older people. Methods The study used data from the prospective observational Three-city cohort and included 1550 community-dwelling individuals aged 72 to 87 without dementia at baseline. Physical activity was assessed with the Voorrips questionnaire. Two sub-scores were calculated to assess household/transportation activities and leisure/sport activities. Restricted cubic spline and proportional hazard Cox models were used to estimate the non-linear exposure-response curve for the dementia risk and the appropriate activity level thresholds. Models were adjusted for possible confounders, including socio-demographic variables, comorbidities, depressive symptoms and APOE genotype. Results The median age was 80 years, and 63.6% of participants were women. After a median follow-up of 4.6 years, dementia was diagnosed in 117 participants (7.6%). An inverse J-shaped association was found between household/transportation physical activity sub-score and dementia risk, which means that the risk is lowest for the moderately high values and then re-increases slightly for the highest values. The results remained significant when this sub-score was categorized in three classes (low, moderate, and high), with hazard ratios (95% confidence interval) of 0.55 (0.35-0.87) and 0.62 (0.38-1.01) for moderate and high activity levels, respectively. No significant effect was found for leisure/sport activities. Conclusions The 5-year risk of dementia was significantly and negatively associated with the household/transportation activity level, but not with the leisure and sport activity sub-score. This highlights the importance of considering all physical activity types in 72 years or older people.

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Physical activity types and risk of dementia in community-dwelling older people: the Three-City cohort.

10.21203/rs.2.17066/v4 ◽

2020 ◽

Author(s):

Caroline Dupré ◽

Bienvenue Bongue ◽

Catherine Helmer ◽

Jean François Dartigues ◽

David Hupin ◽

...

Keyword(s):

Physical Activity ◽

Older People ◽

Sport Activity ◽

Apoe Genotype ◽

Community Dwelling ◽

Activity Level ◽

Activity Levels ◽

Dementia Risk ◽

Sport Activities ◽

Activity Types

Abstract Background Physical activity may decrease the risk of dementia; however, previous cohort studies seldom investigated the different types of physical activity and household activities. Our objective was to analyze the links between two physical activity types and dementia in older people. Methods The study used data from the prospective observational Three-city cohort and included 1550 community-dwelling individuals aged 72 to 87 without dementia at baseline. Physical activity was assessed with the Voorrips questionnaire. Two sub-scores were calculated to assess household/transportation activities and leisure/sport activities. Restricted cubic spline and proportional hazard Cox models were used to estimate the non-linear exposure-response curve for the dementia risk and the appropriate activity level thresholds. Models were adjusted for possible confounders, including socio-demographic variables, comorbidities, depressive symptoms and APOE genotype. Results The median age was 80 years, and 63.6% of participants were women. After a median follow-up of 4.6 years, dementia was diagnosed in 117 participants (7.6%). An inverse J-shaped association was found between household/transportation physical activity sub-score and dementia risk, which means that the risk is lowest for the moderately high values and then re-increases slightly for the highest values. The results remained significant when this sub-score was categorized in three classes (low, moderate, and high), with hazard ratios (95% confidence interval) of 0.55 (0.35-0.87) and 0.62 (0.38-1.01) for moderate and high activity levels, respectively. No significant effect was found for leisure/sport activities. Conclusions The 5-year risk of dementia was significantly and negatively associated with the household/transportation activity level, but not with the leisure and sport activity sub-score. This highlights the importance of considering all physical activity types in 72 years or older people.

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Physical activity and risk of dementia in community-dwelling older people: the Three-City cohort.

10.21203/rs.2.17066/v1 ◽

2019 ◽

Author(s):

Caroline Dupré ◽

Bienvenue Bongue ◽

Catherine Helmer ◽

Jean François Dartigues ◽

David Hupin ◽

...

Keyword(s):

Physical Activity ◽

Older People ◽

Sport Activity ◽

Community Dwelling ◽

Activity Level ◽

Activity Levels ◽

Cox Models ◽

Dementia Risk ◽

Sport Activities ◽

Activity Types

Abstract Background Physical activity may decrease the risk of dementia; however, previous cohort studies seldom investigated the different types of physical activity and household activities. Our objective was to analyze the links between two physical activity types and dementia in older people.Methods The study used data from the prospective observational Three-city cohort and included 1550 community-dwelling individuals aged 72 to 87 without dementia at baseline. Physical activity was assessed with the Voorrips questionnaire. Two sub-scores were calculated to assess household/transportation activities and leisure/sport activities. Restricted cubic spline and proportional hazard Cox models were used to estimate the non-linear exposure-response curve for the dementia risk and the appropriate activity level thresholds. Models were adjusted for possible confounders, including socio-demographic variables, comorbidities, depressive symptoms and APOE genotype.Results The median age was 80 years, and 63.6% of participants were women. After a median follow-up of 4.6 years, dementia was diagnosed in 117 participants (7.6%). An inverse J-shaped association was found between household/transportation physical activity sub-score and dementia risk. The results remained significant when this sub-score was categorized in three classes (low, moderate, and high), with hazard ratios (95% confidence interval) of 0.55 (0.35-0.87) and 0.62 (0.38-1.01) for moderate and high activity levels, respectively. No significant protective effect was found for leisure/sport activities.Conclusions The 5-year risk of dementia was significantly and negatively associated with the household/transportation activity level, but not with the leisure and sport activity sub-score. This highlights the importance of considering all physical activity types in 72 years or older people.

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Physical activity types and risk of dementia in community-dwelling older people: the Three-City cohort

BMC Geriatrics ◽

10.1186/s12877-020-01538-3 ◽

2020 ◽

Vol 20 (1) ◽

Cited By ~ 2

Author(s):

Caroline Dupré ◽

Bienvenu Bongue ◽

Catherine Helmer ◽

Jean François Dartigues ◽

David Hupin ◽

...

Keyword(s):

Physical Activity ◽

Older People ◽

Community Dwelling ◽

Activity Types ◽

Community Dwelling Older People

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Lazy Sundays: role of day of the week and reactivity on objectively measured physical activity in older people

European Review of Aging and Physical Activity ◽

10.1186/s11556-019-0226-1 ◽

2019 ◽

Vol 16 (1) ◽

Cited By ~ 1

Author(s):

Jochen Klenk ◽

◽

Raphael Simon Peter ◽

Kilian Rapp ◽

Dhayana Dallmeier ◽

...

Keyword(s):

Physical Activity ◽

Older People ◽

Community Dwelling ◽

Activity Level ◽

Least Square ◽

Significant Difference ◽

Day Of The Week ◽

Linear Slope ◽

Objectively Measured ◽

Objectively Measured Physical Activity

Abstract Background The aim of this study was to assess the effect of day of the week and wearing a device (reactivity) on objectively measured physical activity (PA) in older people. Methods Walking duration as a measure for PA was recorded from 1333 German community-dwelling older people (≥65 years, 43.8% women) over 5 days using accelerometers (activPAL). Least-square means of PA with 95%-confidence intervals (95%-CI) from multi-level analysis were calculated for each day of the week and each measurement day (days after sensor attachment). Results Walking duration on Sundays was significantly lower compared to working days (Sunday vs. Monday-Friday: − 12.8 min (95%-CI: − 14.7; − 10.9)). No statistically significant difference compared to working days was present for Saturdays. The linear slope for measurement day and walking duration was marginal and not statistically significant. Conclusions Studies using PA sensors in older people should assess Sundays and working days to adequately determine the activity level of the participants.

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Factors influencing physical activity participation among older people with low activity levels

Ageing and Society ◽

10.1017/s0144686x1900076x ◽

2019 ◽

Vol 40 (12) ◽

pp. 2593-2613 ◽

Cited By ~ 1

Author(s):

Rajni Rai ◽

Michelle I. Jongenelis ◽

Ben Jackson ◽

Robert U. Newton ◽

Simone Pettigrew

Keyword(s):

Physical Activity ◽

Older People ◽

Physical Inactivity ◽

Vigorous Physical Activity ◽

Community Dwelling ◽

Activity Levels ◽

Older Individuals ◽

Structured Interviews ◽

Activity Promotion ◽

Low Activity

AbstractDespite the well-documented health benefits of physical activity in older adults, participation levels remain low. With rapid global population ageing, intensive efforts are needed to encourage higher levels of participation to ameliorate the negative effects of physical inactivity for older individuals and society as a whole. The aim of this qualitative study was to inform future physical activity promotion interventions by examining factors contributing to low activity levels among older people undertaking less than half the recommended level of moderate-to-vigorous physical activity (MVPA). Semi-structured interviews were conducted with 102 (65% female) community-dwelling Western Australians aged 60+ years (mean = 71.52, standard deviation = 6.26) who engaged in ⩽75 minutes of MVPA per week as measured by accelerometers. Several modifiable and unmodifiable barriers were identified, of which poor health featured most prominently. Lifetime physical inactivity, caring duties, low motivation, misperceptions of physical activity and ageing, and a lack of affordable and attractive options were the other barriers identified. The results suggest that strategies are needed to raise awareness of current physical activity guidelines, normalise engagement in MVPA throughout the lifespan, develop initiatives to motivate participation, improve the availability of affordable physical activity programmes that are attractive to this population segment, and facilitate participation among those with intensive caring responsibilities.

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Associations between physical activity types and multi-domain cognitive decline in older adults from the Three-city cohort

PLoS ONE ◽

10.1371/journal.pone.0252500 ◽

2021 ◽

Vol 16 (6) ◽

pp. e0252500

Author(s):

Caroline Dupré ◽

Catherine Helmer ◽

Bienvenu Bongue ◽

Jean François Dartigues ◽

Frédéric Roche ◽

...

Keyword(s):

Physical Activity ◽

Older Adults ◽

Cognitive Decline ◽

Cognitive Abilities ◽

Neuroprotective Effect ◽

Community Dwelling ◽

Sport Activities ◽

Trail Making ◽

Activity Types

Several studies suggest that physical activity improves cognitive functions and reduces cognitive decline, whereas others did not find any evidence of a neuroprotective effect. Furthermore, few cohort studies have analyzed the different physical activity types and particularly household activities. Our objective was to assess the association of two physical activity types with the decline in different cognitive domains in a large prospective cohort of community-dwelling older adults from the Three-city study. Physical activity (domestic/transportation activities and leisure/sport activities) was assessed with the Voorrips questionnaire, specific for older adults. Baseline sociodemographic and health history variables as well as cognitive performance data at baseline and during the 8-year follow-up (Mini-Mental State Examination, Benton Visual Retention Test, Trail Making Tests A and B, Isaac’s Set Test and Free and Cued Selective Reminding Test) were also available. Associations between physical activity scores and cognitive decline in different domains were tested using minimally- and multi-adjusted linear mixed models. The analysis included 1697 participants without dementia at baseline and with at least one follow-up visit. At baseline, participants with higher sub-scores for the two physical activity types had better cognitive performances. Interaction with time showed that decline in some cognitive scores (Trail Making Test B and Isaac’s Set Test) was significantly less pronounced in participants with higher household/transportation activity sub-scores. No significant effect over time was found for leisure/sport activities. This study shows that during an 8-year follow-up, executive functions and verbal fluency were better preserved in older adults who performed household/transportation activities at moderate to high level. Participation in domestic activities and using adapted transport means could allow older adults to maintain specific cognitive abilities.

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PHYSICAL INACTIVITY AND HIGH SEDENTARY BEHAVIOR ARE ASSOCIATED WITH HYPERTRIGLYCERIDEMIC WAIST IN ELDERLY

Estudos Interdisciplinares sobre o Envelhecimento ◽

10.22456/2316-2171.98245 ◽

2021 ◽

Vol 26 (1) ◽

Author(s):

Lucas Dos Santos ◽

Luciano Alves da Cruz Junior ◽

Luara Costa Fagunde ◽

Jessica Meira Mendes ◽

Thais Alves Brito ◽

...

Keyword(s):

Physical Activity ◽

Sedentary Behaviour ◽

Physical Activity Level ◽

Population Based ◽

Community Dwelling ◽

Activity Level ◽

Activity Levels ◽

Cross Sectional ◽

Hypertriglyceridemic Waist ◽

Physical Activity Levels

During aging, an increase in sedentary behaviour and a decrease in physical activity levels are observed. These factors may increase abdominal adiposity and triglyceride levels, which characterizes the hypertriglyceridemic waist (HW) phenotype, providing a high risk for cardiometabolic diseases. This study aimed to analyze the association between hypertriglyceridemic waist, physical activity level and sedentary behaviour in community-dwelling elderly. A population-based cross-sectional study was carried out, involving 316 elderlies (≥ 60 years) of both genders. The hypertriglyceridemic waist was diagnosed using high triglycerides (≥ 150 mg/dl) and increased waist circumference ≥ 88 and ≥ 102 cm values for women and men, respectively. The physical activity level and sedentary behaviour were evaluated using the IPAQ. The study included 173 women (54.7%) and 143 men (45.3%), with a mean age of 74.2 ± 9.8 years. The prevalence of HW was 27.1%, 47.7% insufficiently active and 24.1% high sedentary behaviour. The insufficiently active elderly (OR= 2.48; 95% CI: 1.31 - 4.71; p= 0.005) and with high sedentary behaviour (OR= 2.21; 95% CI: 1.04 - 4.32; p= 0.038) were associated positively with HW, indicating that elderly with insufficient physical activity levels and high sedentary behaviour showed themselves to approximately 2.5 and 2.2 times more likely to develop HW, respectively. Low physical activity level and high sedentary behaviour are associated with hypertriglyceridemic waist in community-dwelling elderly.

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Validation of the Human Activity Profile Questionnaire as a Measure of Physical Activity Levels in Older Community-Dwelling Women

Journal of Aging and Physical Activity ◽

10.1123/japa.2012-0283 ◽

2014 ◽

Vol 22 (3) ◽

pp. 348-356 ◽

Cited By ~ 9

Author(s):

Alessandra de Carvalho Bastone ◽

Bruno de Souza Moreira ◽

Renata Alvarenga Vieira ◽

Renata Noce Kirkwood ◽

João Marcos Domingues Dias ◽

...

Keyword(s):

Physical Activity ◽

Older Women ◽

Human Activity ◽

Community Dwelling ◽

Activity Level ◽

Activity Levels ◽

Accelerometer Data ◽

Activity Profile ◽

Physical Activity Levels ◽

Cutoff Points

The purpose of this study was to assess the validity of the Human Activity Profile (HAP) by comparing scores with accelerometer data and by objectively testing its cutoff points. This study included 120 older women (age 60–90 years). Average daily time spent in sedentary, moderate, and hard activity; counts; number of steps; and energy expenditure were measured using an accelerometer. Spearman rank order correlations were used to evaluate the correlation between the HAP scores and accelerometer variables. Significant relationships were detected (rho = .47−.75, p < .001), indicating that the HAP estimates physical activity at a group level well; however, scatterplots showed individual errors. Receiver operating characteristic curves were constructed to determine HAP cutoff points on the basis of physical activity level recommendations, and the cutoff points found were similar to the original HAP cutoff points. The HAP is a useful indicator of physical activity levels in older women.

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Do Automatic Habits Predict Physical Activity Engagement in Older People?

Innovation in Aging ◽

10.1093/geroni/igaa057.1602 ◽

2020 ◽

Vol 4 (Supplement_1) ◽

pp. 496-496

Author(s):

Sophie Andrews ◽

Dinaz Parekh ◽

Brooke Brady ◽

Kim Delbaere ◽

Simon Killcross ◽

...

Keyword(s):

Physical Activity ◽

Older People ◽

Physical Activity Behaviour ◽

Community Dwelling ◽

Self Report ◽

Depression Symptoms ◽

Activity Levels ◽

Online Questionnaire ◽

Vigorous Exercise ◽

Activity Engagement

Abstract Sufficient physical activity is crucial to maintaining independence, health and wellbeing during ageing, yet physical inactivity is common in older people. Identifying factors associated with physical activity engagement is essential to develop novel approaches to increase activity in older people. Automatic, context-dependent habits may play an important role in physical activity behaviour. The current study aimed to investigate the relationship between physical activity behaviours and their automaticity in older people. 123 community dwelling Australians aged over 65 – 88 years (M=72.2; 81 women), recruited from participant registries, hospital noticeboards and community groups, completed an online questionnaire. Current physical activity levels were measured using the Incidental and Planned Exercise Questionnaire, and automaticity of those physical activity behaviours were measured using the Self-Report Habit Automaticity Index. Participants also reported demographic information, body mass index (BMI), medical history and current mood symptoms. Participants reported an average of 2.28 hours planned walking (SD=2.33), 5.81 hours planned moderate/vigorous exercise (SD=4.02), and 20.5 hours incidental activity (SD=15.52) per week. Multiple regression analyses revealed that after controlling for age, gender, BMI and depression symptoms, higher automaticity scores were associated with more hours per week of planned walking (p=.012), moderate/vigorous exercise (p=.038), and incidental activity (p=.017). Supporting older people to make their physical activity more habitual could therefore be an effective approach to increase levels of physical activity in this population.

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